Draft Rookie Player draft -- Debut
| Draft Picks |
| Overall | Rd | # | Orig Team | Curr Team | # | Player |
| 1 | 1 | 1 | TB22 | | | 2022 Wander Franco |
| 2 | 1 | 2 | Tex22 | | | 2022 Jonathan India |
| 3 | 1 | 3 | Cle22 | | | 2022 Jarred Kelenic |
| 4 | 1 | 4 | NYM22 | | | 2022 Alek Manoah |
| 5 | 1 | 5 | StL22 | | | 2022 Alex Kirilloff |
| 6 | 1 | 6 | SF22 | | | 2022 Andrew Vaughn |
| 7 | 1 | 7 | Pit22 | | | 2022 Oneil Cruz |
| 8 | 1 | 8 | Phi22 | | | 2022 Shane McClanahan |
| 9 | 1 | 9 | KC22 | | | 2022 Logan Gilbert |
| 10 | 1 | 10 | Hou22 | | | 2022 Shane Baz |
| 11 | 1 | 11 | Tor22 | | | 2022 Edward Cabrera |
| 12 | 1 | 12 | Ari22 | | | 2022 Reid Detmers |
| 13 | 1 | 13 | Atl22 | | | 2022 Matt Manning |
| 14 | 1 | 14 | LAD22 | | | 2022 Brandon Marsh |
| 15 | 1 | 15 | Min22 | | | 2022 Daniel Lynch |
| 16 | 1 | 16 | Oak22 | StL22 | | 2022 Aaron Ashby |
| 17 | 1 | 17 | SD22 | TB22 | | 2022 Vidal Brujan |
| 18 | 1 | 18 | LAA22 | StL22 | | 2022 Josiah Gray |
| 19 | 1 | 19 | NYY22 | | | 2022 Joe Ryan |
| 20 | 1 | 20 | Cin22 | ChW22 | | 2022 Geraldo Perdomo |
| 21 | 1 | 21 | Col22 | | | 2022 Josh Lowe |
| 22 | 1 | 22 | ChC22 | Min22 | | 2022 Bryan De La Cruz |
| 23 | 1 | 23 | Mia22 | NYY22 | | 2022 Jarren Duran |
| 24 | 1 | 24 | Sea22 | Atl22 | | 2022 Ryan Weathers |
| 25 | 1 | 25 | ChW22 | Cin22 | | 2022 Akil Baddoo |
| 26 | 1 | 26 | Det22 | | | 2022 Kyle Isbel |
| 27 | 1 | 27 | Bos22 | Min22 | | 2022 Tylor Megill |
| 28 | 1 | 28 | Mil22 | Phi22 | | 2022 Seth Beer |
| 29 | 1 | 29 | Was22 | | | 2022 Roansy Contreras |
| 30 | 1 | 30 | Bal22 | | | 2022 Kyle Muller |
| 31 | 2 | 1 | TB22 | | | 2022 Trevor Larnach |
| 32 | 2 | 2 | Tex22 | ChC22 | | 2022 Cal Raleigh |
| 33 | 2 | 3 | Cle22 | | | 2022 Taylor Walls |
| 34 | 2 | 4 | NYM22 | | | |
| 35 | 2 | 5 | StL22 | | | 2022 Bailey Ober |
| 36 | 2 | 6 | SF22 | | | 2022 Gavin Sheets |
| 37 | 2 | 7 | Pit22 | | | 2022 Matt Vierling |
| 38 | 2 | 8 | Phi22 | | | 2022 A.J. Alexy |
| 39 | 2 | 9 | KC22 | | | 2022 Vladimir Gutierrez |
| 40 | 2 | 10 | Hou22 | | | 2022 Luis Gil |
| 41 | 2 | 11 | Tor22 | LAA22 | | 2022 Chas McCormick |
| 42 | 2 | 12 | Ari22 | | | 2022 Garrett Whitlock |
| 43 | 2 | 13 | Atl22 | | | 2022 Jake Meyers |
| 44 | 2 | 14 | LAD22 | | | 2022 Lars Nootbaar |
| 45 | 2 | 15 | Min22 | | | 2022 Jackson Kowar |
| 46 | 2 | 16 | Oak22 | StL22 | | 2022 Spencer Strider |
| 47 | 2 | 17 | SD22 | | | 2022 Otto Lopez |
| 48 | 2 | 18 | LAA22 | | | 2022 Zach Thompson |
| 49 | 2 | 19 | NYY22 | Cle22 | | 2022 Griffin Jax |
| 50 | 2 | 20 | Cin22 | | | |
| 51 | 2 | 21 | Col22 | Phi22 | | 2022 Eli Morgan |
| 52 | 2 | 22 | ChC22 | Bal22 | | 2022 Ha-Seong Kim |
| 53 | 2 | 23 | Mia22 | Sea22 | | 2022 Hans Crouse |
| 54 | 2 | 24 | Sea22 | Cle22 | | 2022 Justin Steele |
| 55 | 2 | 25 | ChW22 | | | 2022 Taylor Trammell |
| 56 | 2 | 26 | Det22 | ChC22 | | 2022 Jake Burger |
| 57 | 2 | 27 | Bos22 | Min22 | | 2022 Ryan Vilade |
| 58 | 2 | 28 | Mil22 | | | 2022 Andy Ibanez |
| 59 | 2 | 29 | Was22 | | | 2022 Nick Gordon |
| 60 | 2 | 30 | Bal22 | Phi22 | | 2022 Kevin Smith |
| 61 | 3 | 1 | TB22 | | | 2022 Colton Welker |
| 62 | 3 | 2 | Tex22 | | | |
| 63 | 3 | 3 | Cle22 | | | 2022 Ben Rortvedt |
| 64 | 3 | 4 | NYM22 | | | 2022 Khalil Lee |
| 65 | 3 | 5 | StL22 | | | 2022 Tyler Wells |
| 66 | 3 | 6 | SF22 | | | 2022 Riley Adams |
| 67 | 3 | 7 | Pit22 | NYY22 | | 2022 Anthony Bender |
| 68 | 3 | 8 | Phi22 | | | 2022 Jake McCarthy |
| 69 | 3 | 9 | KC22 | SF22 | | 2022 Chris Rodriguez |
| 70 | 3 | 10 | Hou22 | | | 2022 Jose Devers |
| 71 | 3 | 11 | Tor22 | | | 2022 Sam Hentges |
| 72 | 3 | 12 | Ari22 | | | 2022 Alec Bettinger |
| 73 | 3 | 13 | Atl22 | ChC22 | | 2022 Camilo Doval |
| 74 | 3 | 14 | LAD22 | | | 2022 Joe Barlow |
| 75 | 3 | 15 | Min22 | NYM22 | | 2022 Jake Brentz |
| 76 | 3 | 16 | Oak22 | SF22 | | 2022 Keegan Thompson |
| 77 | 3 | 17 | SD22 | | | 2022 Connor Seabold |
| 78 | 3 | 18 | LAA22 | Pit22 | | 2022 Jose Siri |
| 79 | 3 | 19 | NYY22 | Tex22 | | 2022 Reiver Sanmartin |
| 80 | 3 | 20 | Cin22 | Cle22 | | 2022 Lucas Gilbreath |
| 81 | 3 | 21 | Col22 | | | 2022 Joan Adon |
| 82 | 3 | 22 | ChC22 | Hou22 | | 2022 Ryan McKenna |
| 83 | 3 | 23 | Mia22 | Tex22 | | 2022 Luke Williams |
| 84 | 3 | 24 | Sea22 | | | 2022 Andre Jackson |
| 85 | 3 | 25 | ChW22 | | | 2022 Tony Santillan |
| 86 | 3 | 26 | Det22 | | | 2022 Angel Zerpa |
| 87 | 3 | 27 | Bos22 | Cle22 | | 2022 Zach Pop |
| 88 | 3 | 28 | Mil22 | Hou22 | | 2022 Owen Miller |
| 89 | 3 | 29 | Was22 | | | 2022 Nick Sandlin |
| 90 | 3 | 30 | Bal22 | Bos22 | | 2022 Romy Gonzalez |
| 91 | 4 | 1 | TB22 | | | 2022 Tyler Gilbert |
| 92 | 4 | 2 | Tex22 | | | 2022 Hirokazu Sawamura |
| 93 | 4 | 3 | Cle22 | Atl22 | | 2022 Tucupita Marcano |
| 94 | 4 | 4 | NYM22 | | | |
| 95 | 4 | 5 | StL22 | | | 2022 Justin Bruihl |
| 96 | 4 | 6 | SF22 | Oak22 | | 2022 Yonny Hernandez |
| 97 | 4 | 7 | Pit22 | | | 2022 Rodolfo Castro |
| 98 | 4 | 8 | Phi22 | | | 2022 Alejo Lopez |
| 99 | 4 | 9 | KC22 | | | 2022 Sebastian Rivero |
| 100 | 4 | 10 | Hou22 | | | 2022 Mike Baumann |
| 101 | 4 | 11 | Tor22 | | | 2022 Nick Maton |
| 102 | 4 | 12 | Ari22 | | | 2022 Cooper Criswell |
| 103 | 4 | 13 | Atl22 | | | |
| 104 | 4 | 14 | LAD22 | | | 2022 Hoy Jun Park |
| 105 | 4 | 15 | Min22 | ChC22 | | 2022 TJ Friedl |
| 106 | 4 | 16 | Oak22 | | | 2022 Stephen Ridings |
| 107 | 4 | 17 | SD22 | | | 2022 Gilberto Celestino |
| 108 | 4 | 18 | LAA22 | | | 2022 Ernie Clement |
| 109 | 4 | 19 | NYY22 | Bos22 | | 2022 Mario Feliciano |
| 110 | 4 | 20 | Cin22 | Hou22 | | 2022 Kervin Castro |
| 111 | 4 | 21 | Col22 | | | 2022 Jake Cousins |
| 112 | 4 | 22 | ChC22 | | | 2022 Louis Head |
| 113 | 4 | 23 | Mia22 | | | 2022 Marcos Diplan |
| 114 | 4 | 24 | Sea22 | Pit22 | | 2022 Dylan Coleman |
| 115 | 4 | 25 | ChW22 | Cin22 | | 2022 Jordan Sheffield |
| 116 | 4 | 26 | Det22 | | | 2022 Alfonso Rivas |
| 117 | 4 | 27 | Bos22 | | | 2022 Tyler Nevin |
| 118 | 4 | 28 | Mil22 | Phi22 | | 2022 Tyler Ivey |
| 119 | 4 | 29 | Was22 | | | 2022 Alan Trejo |
| 120 | 4 | 30 | Bal22 | | | 2022 Glenn Otto |
| 121 | 5 | 1 | TB22 | | | 2022 DJ Peters |
| 122 | 5 | 2 | Tex22 | | | 2022 Mason Thompson |
| 123 | 5 | 3 | Cle22 | | | |
| 124 | 5 | 4 | NYM22 | | | 2022 Trevor Stephan |
| 125 | 5 | 5 | StL22 | | | 2022 Zac Lowther |
| 126 | 5 | 6 | SF22 | | | 2022 Tayler Saucedo |
| 127 | 5 | 7 | Pit22 | | | 2022 Max Kranick |
| 128 | 5 | 8 | Phi22 | | | |
| 129 | 5 | 9 | KC22 | | | 2022 Jose Rojas |
| 130 | 5 | 10 | Hou22 | | | 2022 Drew Ellis |
| 131 | 5 | 11 | Tor22 | | | |
| 132 | 5 | 12 | Ari22 | | | 2022 Kutter Crawford |
| 133 | 5 | 13 | Atl22 | | | 2022 Yohel Pozo |
| 134 | 5 | 14 | LAD22 | | | 2022 Brent Honeywell |
| 135 | 5 | 15 | Min22 | ChC22 | | 2022 Janson Junk |
| 136 | 5 | 16 | Oak22 | Sea22 | | 2022 Bailey Falter |
| 137 | 5 | 17 | SD22 | | | 2022 Curtis Terry |
| 138 | 5 | 18 | LAA22 | Phi22 | | 2022 Sammy Long |
| 139 | 5 | 19 | NYY22 | | | 2022 Luke Raley |
| 140 | 5 | 20 | Cin22 | Bos22 | | 2022 Angel Rondon |
| 141 | 5 | 21 | Col22 | | | 2022 Emmanuel Rivera |
| 142 | 5 | 22 | ChC22 | Det22 | | 2022 Austin Warren |
| 143 | 5 | 23 | Mia22 | | | 2022 Matt Peacock |
| 144 | 5 | 24 | Sea22 | | | 2022 Luis Barrera |
| 145 | 5 | 25 | ChW22 | | | 2022 Zack Short |
| 146 | 5 | 26 | Det22 | | | 2022 Edwin Uceta |
| 147 | 5 | 27 | Bos22 | NYM22 | | 2022 Stuart Fairchild |
| 148 | 5 | 28 | Mil22 | | | 2022 Peter Solomon |
| 149 | 5 | 29 | Was22 | | | 2022 Andrew Wantz |
| 150 | 5 | 30 | Bal22 | | | 2022 Luis Frias |
| 151 | 6 | 1 | TB22 | | | 2022 Nick Fortes |
| 152 | 6 | 2 | Tex22 | LAA22 | | 2022 Gregory Santos |
| 153 | 6 | 3 | Cle22 | | | 2022 Sam Clay |
| 154 | 6 | 4 | NYM22 | | | 2022 Ka'ai Tom |
| 155 | 6 | 5 | StL22 | | | |
| 156 | 6 | 6 | SF22 | NYM22 | | 2022 J.C. Mejia |
| 157 | 6 | 7 | Pit22 | | | 2022 Jon Heasley |
| 158 | 6 | 8 | Phi22 | | | 2022 Patrick Mazeika |
| 159 | 6 | 9 | KC22 | | | 2022 Luis Oviedo |
| 160 | 6 | 10 | Hou22 | SD22 | | 2022 Jhonathan Diaz |
| 161 | 6 | 11 | Tor22 | | | 2022 Kohei Arihara |
| 162 | 6 | 12 | Ari22 | | | 2022 Ryan Feltner |
| 163 | 6 | 13 | Atl22 | Tor22 | | 2022 Kyle Tyler |
| 164 | 6 | 14 | LAD22 | | | 2022 Brett De Geus |
| 165 | 6 | 15 | Min22 | NYM22 | | 2022 Zach Reks |
| 166 | 6 | 16 | Oak22 | | | 2022 Michael Rucker |
| 167 | 6 | 17 | SD22 | ChW22 | | 2022 Ralph Garza |
| 168 | 6 | 18 | LAA22 | Tor22 | | 2022 Cody Poteet |
| 169 | 6 | 19 | NYY22 | ChC22 | | 2022 Reiss Knehr |
| 170 | 6 | 20 | Cin22 | | | 2022 Scott Effross |
| 171 | 6 | 21 | Col22 | | | 2022 Johneshwy Fargas |
| 172 | 6 | 22 | ChC22 | | | |
| 173 | 6 | 23 | Mia22 | Det22 | | 2022 Connor Wong |
| 174 | 6 | 24 | Sea22 | | | 2022 Manuel Rodriguez |
| 175 | 6 | 25 | ChW22 | NYM22 | | 2022 Thomas Szapucki |
| 176 | 6 | 26 | Det22 | Tex22 | | 2022 Alexander Wells |
| 177 | 6 | 27 | Bos22 | | | 2022 Jovani Moran |
| 178 | 6 | 28 | Mil22 | | | 2022 Greg Deichmann |
| 179 | 6 | 29 | Was22 | | | 2022 Kent Emanuel |
| 180 | 6 | 30 | Bal22 | | | 2022 Jose Marte |
| 181 | 7 | 1 | TB22 | | | 2022 Charlie Barnes |
| 182 | 7 | 2 | Pit22 | | | 2022 Jake Latz |
| 183 | 7 | 3 | KC22 | | | 2022 Francisco Perez |
| 184 | 7 | 15 | Min22 | Tor22 | | 2022 Spenser Watkins |
| 185 | 7 | 18 | LAA22 | ChW22 | | 2022 Webster Rivas |
| 186 | 7 | 19 | NYY22 | ChC22 | | 2022 Kevin Padlo |
| 187 | 7 | 23 | Mia22 | Col22 | | 2022 Domingo Acevedo |
| 188 | 7 | 8 | Sea22 | | | 2022 Alex Lange |
| 189 | 7 | 25 | ChW22 | NYM22 | | 2022 Jacob Robson |
| 190 | 7 | 10 | Det22 | | | 2022 Miguel Sanchez |
| 191 | 7 | 11 | Bos22 | | | 2022 Oliver Ortega |
| 192 | 7 | 12 | Mil22 | | | 2022 Darien Nunez |
| 193 | 7 | 13 | Was22 | | | 2022 Jake Reed |
| 194 | 7 | 14 | Bal22 | | | 2022 Cory Abbott |