Team game results - 2021 Houston Astros
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/15/2021 | | | Sea | L | 2-5 | | Walker, T | R | Walker, T | | Minor, M | L |
| 4/15/2021 | | @ | Oak | W | 3-2 | | Walker, T | R | Stammen, C | Gallegos, G | Scherzer, M | R |
| 4/16/2021 | | | Sea | L | 4-6 | | Dunn, J | R | Matzek, T | | Glasnow, T | R |
| 4/16/2021 | | @ | Oak | L | 0-1 | 11 | Dunn, J | R | Armstrong, S | | Cueto, J | R |
| 4/17/2021 | | | Sea | L | 3-9 | 12 | Hill, R | L | Stammen, C | | Skubal, T | L |
| 4/17/2021 | | @ | Oak | W | 6-5 | 11 | Gray, J | R | Stammen, C | Armstrong, S | Fried, M | L |
| 4/19/2021 | | | Tex | L | 3-4 | | Smyly, D | L | Guerra, J | | Fulmer, M | R |
| 4/19/2021 | | @ | LAA | L | 7-13 | | Hill, R | L | Hill, R | | Boyd, M | L |
| 4/20/2021 | | | Tex | L | 2-3 | | Walker, T | R | Walker, T | | McKenzie, T | R |
| 4/20/2021 | | @ | LAA | L | 0-3 | | Smyly, D | L | Smyly, D | | Darvish, Y | R |
| 4/21/2021 | | | Tex | W | 12-11 | 12 | Dunn, J | R | Gallegos, G | | Thorpe, L | L |
| 4/21/2021 | | @ | LAA | L | 1-4 | | Walker, T | R | Walker, T | | Yarbrough, R | L |
| 4/22/2021 | | | LAA | W | 4-0 | | Hill, R | L | Hill, R | | Toussaint, T | R |
| 4/22/2021 | | @ | Tex | L | 3-4 | 11 | Dunn, J | R | Armstrong, S | | Eshelman, T | R |
| 4/23/2021 | | | LAA | L | 5-13 | | Gray, J | R | Gray, J | | Yarbrough, R | L |
| 4/23/2021 | | @ | Tex | W | 7-2 | | Gray, J | R | Gray, J | | Sanchez, A | R |
| 4/24/2021 | | | LAA | L | 2-3 | | Walker, T | R | Hand, B | | Darvish, Y | R |
| 4/24/2021 | | @ | Tex | L | 5-7 | | Hill, R | L | Hill, R | | McKenzie, T | R |
| 4/26/2021 | | | Oak | W | 3-2 | | Smyly, D | L | Smyly, D | Hand, B | Fried, M | L |
| 4/26/2021 | | @ | Sea | W | 2-1 | | Smyly, D | L | Guerra, J | Gallegos, G | Urquidy, J | R |
| 4/27/2021 | | | Oak | L | 0-6 | | Dunn, J | R | Dunn, J | | Scherzer, M | R |
| 4/27/2021 | | @ | Sea | L | 4-6 | | Walker, T | R | Walker, T | | Glasnow, T | R |
| 4/28/2021 | | | Oak | L | 2-3 | 10 | Gray, J | R | Hand, B | | Kuhl, C | R |
| 4/28/2021 | | @ | Sea | L | 2-5 | | Dunn, J | R | Dunn, J | | Fedde, E | R |
| 5/13/2021 | | | StL | L | 2-7 | | Hill, R | L | Hill, R | | Carrasco, C | R |
| 5/13/2021 | | @ | Phi | L | 3-5 | | Walker, T | R | Walker, T | | Clevinger, M | R |
| 5/14/2021 | | | StL | W | 7-1 | | Walker, T | R | Walker, T | | Heaney, A | L |
| 5/14/2021 | | @ | Phi | W | 3-1 | | Dunn, J | R | Dunn, J | Hand, B | Castillo, L | R |
| 5/15/2021 | | | StL | W | 7-6 | | Dunn, J | R | Guerra, J | Hand, B | Ray, R | L |
| 5/15/2021 | | @ | Phi | L | 3-4 | | Gray, J | R | Gray, J | | Sheffield, J | L |
| 5/17/2021 | | @ | Atl | L | 1-2 | 11 | Hill, R | L | Guerra, J | | Barria, J | R |
| 5/17/2021 | | | Pit | W | 6-5 | | Smyly, D | L | Guerra, J | Hand, B | McCullers, L | R |
| 5/18/2021 | | @ | Atl | L | 3-4 | 16 | Smyly, D | L | Santana, D | | Castellani, R | R |
| 5/18/2021 | | | Pit | W | 7-1 | | Hill, R | L | Hill, R | Stammen, C | Davies, Z | R |
| 5/19/2021 | | @ | Atl | W | 5-1 | | Walker, T | R | Walker, T | | Milone, T | L |
| 5/19/2021 | | | Pit | W | 3-1 | | Gray, J | R | Gray, J | Hand, B | Sandoval, P | L |
| 5/21/2021 | | | ChC | W | 8-3 | | Walker, T | R | Walker, T | Matzek, T | Montas, F | R |
| 5/21/2021 | | @ | NYM | W | 6-0 | | Dunn, J | R | Dunn, J | | Mengden, D | R |
| 5/22/2021 | | | ChC | L | 1-11 | | Dunn, J | R | Dunn, J | | Happ, J | L |
| 5/22/2021 | | @ | NYM | W | 8-2 | | Ponce de Leon, D | R | Ponce de Leon, D | | Luzardo, J | L |
| 5/23/2021 | | | ChC | L | 0-8 | | Hill, R | L | Hill, R | | Greinke, Z | R |
| 5/23/2021 | | @ | NYM | W | 5-3 | | Hill, R | L | Hill, R | Gallegos, G | Dunning, D | R |
| 5/24/2021 | | | Cin | L | 3-6 | | Smyly, D | L | Guerra, J | | Lyles, J | R |
| 5/24/2021 | | @ | Was | L | 3-4 | | Smyly, D | L | Smyly, D | | Kelly, M | R |
| 5/25/2021 | | | Cin | L | 2-6 | | Gray, J | R | Gray, J | | Plesac, Z | R |
| 5/25/2021 | | @ | Was | L | 1-2 | | Walker, T | R | Walker, T | | Buehler, W | R |
| 5/26/2021 | | | Cin | W | 5-4 | 10 | Walker, T | R | Hand, B | | Woodruff, B | R |
| 5/26/2021 | | @ | Was | L | 4-7 | | Dunn, J | R | Dunn, J | | Hendricks, K | R |
| 5/28/2021 | | | Mil | W | 3-2 | | Dunn, J | R | Dunn, J | Hand, B | Richards, G | R |
| 5/28/2021 | | @ | Mia | L | 3-5 | | Gray, J | R | Gray, J | | Valdez, F | L |
| 5/29/2021 | | | Mil | L | 3-11 | | Hill, R | L | Hill, R | | Morton, C | R |
| 5/29/2021 | | @ | Mia | L | 3-14 | | Hill, R | L | Hill, R | | Eflin, Z | R |
| 5/30/2021 | | | Mil | W | 7-1 | | Gray, J | R | Gray, J | | Smith, C | L |
| 5/30/2021 | | @ | Mia | W | 6-4 | | Ponce de Leon, D | R | Ponce de Leon, D | | Tomlin, J | R |
| 6/14/2021 | | | Bal | L | 2-5 | | Ponce de Leon, D | R | Gallegos, G | | Mills, A | R |
| 6/14/2021 | | @ | ChW | L | 4-5 | | Walker, T | R | Guerra, J | | Eovaldi, N | R |
| 6/15/2021 | | | Bal | L | 2-5 | | Walker, T | R | Walker, T | | Cobb, A | R |
| 6/15/2021 | | @ | ChW | W | 4-3 | | Dunn, J | R | Dunn, J | Hand, B | Tanaka, M | R |
| 6/16/2021 | | | Bal | W | 3-2 | | Dunn, J | R | Dunn, J | Hand, B | Cahill, T | R |
| 6/16/2021 | | @ | ChW | L | 5-8 | | Gray, J | R | Gray, J | | Keller, M | R |
| 6/17/2021 | | | Bos | L | 0-6 | | Hill, R | L | Hill, R | | Hudson, D | R |
| 6/17/2021 | | @ | Min | L | 0-2 | | Hill, R | L | Hill, R | | Akin, K | L |
| 6/18/2021 | | | Bos | L | 5-10 | | Gray, J | R | Gray, J | | Webb, L | R |
| 6/18/2021 | | @ | Min | L | 1-2 | | Ponce de Leon, D | R | Ponce de Leon, D | | Mahle, T | R |
| 6/19/2021 | | | Bos | W | 3-2 | | Ponce de Leon, D | R | Ponce de Leon, D | Guerra, J | Ynoa, H | R |
| 6/19/2021 | | @ | Min | L | 3-7 | | Walker, T | R | Walker, T | | Nola, A | R |
| 6/21/2021 | | | NYY | W | 5-2 | | Walker, T | R | Walker, T | Hand, B | Burnes, C | R |
| 6/21/2021 | | @ | Cle | L | 1-5 | | Dunn, J | R | Dunn, J | | Keller, B | R |
| 6/22/2021 | | | NYY | W | 2-1 | | Dunn, J | R | Hand, B | | Bundy, D | R |
| 6/22/2021 | | @ | Cle | L | 0-6 | | Gray, J | R | Gray, J | | Zimmermann, J | R |
| 6/23/2021 | | | NYY | W | 6-3 | | Gray, J | R | Gallegos, G | | May, D | R |
| 6/23/2021 | | @ | Cle | L | 4-11 | | Hill, R | L | Hill, R | | Bielak, B | R |
| 6/24/2021 | | | TB | L | 2-3 | | Hill, R | L | Hand, B | | Wright, K | R |
| 6/24/2021 | | @ | Det | L | 4-5 | | Ponce de Leon, D | R | Ponce de Leon, D | | Bauer, T | R |
| 6/25/2021 | | | TB | W | 4-2 | | Ponce de Leon, D | R | Ponce de Leon, D | Hand, B | Canning, G | R |
| 6/25/2021 | | @ | Det | L | 0-1 | | Walker, T | R | Walker, T | | Marquez, G | R |
| 6/26/2021 | | | TB | W | 5-1 | | Walker, T | R | Walker, T | Guerra, J | Smeltzer, D | L |
| 6/26/2021 | | @ | Det | L | 3-4 | 10 | Dunn, J | R | Hand, B | | Cody, K | R |
| 6/28/2021 | | | Tor | W | 9-0 | | Dunn, J | R | Dunn, J | | Miley, W | L |
| 6/28/2021 | | @ | KC | L | 1-12 | | Gray, J | R | Gray, J | | Singer, B | R |
| 6/29/2021 | | | Tor | W | 7-2 | | Gray, J | R | Gray, J | | Roark, T | R |
| 6/29/2021 | | @ | KC | W | 5-0 | | Hill, R | L | Hill, R | | Lindblom, J | R |
| 6/30/2021 | | | Tor | W | 9-2 | | Ponce de Leon, D | R | Gallegos, G | | Lorenzen, M | R |
| 6/30/2021 | | @ | KC | W | 8-5 | | Ponce de Leon, D | R | Guerra, J | Hand, B | Rogers, T | L |
| 7/15/2021 | | | Tex | W | 6-4 | | Walker, T | R | Matzek, T | Hand, B | McKenzie, T | R |
| 7/15/2021 | | @ | LAA | W | 7-3 | | Walker, T | R | Walker, T | | Yarbrough, R | L |
| 7/16/2021 | | | Tex | L | 5-7 | | Dunn, J | R | Hand, B | | Teheran, J | R |
| 7/16/2021 | | @ | LAA | L | 3-13 | | Ponce de Leon, D | R | Ponce de Leon, D | | Darvish, Y | R |
| 7/17/2021 | | | Tex | W | 4-1 | | Hill, R | L | Hill, R | Matzek, T | Thorpe, L | L |
| 7/17/2021 | | @ | LAA | L | 1-4 | | Hill, R | L | Hill, R | | Gomber, A | L |
| 7/19/2021 | | | Oak | L | 2-5 | | Gray, J | R | Gray, J | | Kuhl, C | R |
| 7/19/2021 | | @ | Sea | L | 0-11 | | Dunn, J | R | Dunn, J | | Urquidy, J | R |
| 7/20/2021 | | | Oak | L | 2-3 | | Walker, T | R | Guerra, J | | Fried, M | L |
| 7/20/2021 | | @ | Sea | L | 2-7 | | Gray, J | R | Gray, J | | Minor, M | L |
| 7/21/2021 | | | Oak | W | 7-4 | | Ponce de Leon, D | R | Heller, B | Hand, B | Cueto, J | R |
| 7/21/2021 | | @ | Sea | L | 1-5 | | Walker, T | R | Walker, T | | Glasnow, T | R |
| 7/22/2021 | | | Sea | L | 2-14 | | Hill, R | L | Hill, R | | Keller, B | R |
| 7/22/2021 | | @ | Oak | L | 2-14 | | Ponce de Leon, D | R | Ponce de Leon, D | | Cueto, J | R |
| 7/23/2021 | | | Sea | L | 0-6 | | Dunn, J | R | Dunn, J | | Wisler, M | R |
| 7/23/2021 | | @ | Oak | L | 2-8 | | Hill, R | L | Hill, R | | Scherzer, M | R |
| 7/24/2021 | | | Sea | W | 3-2 | | Walker, T | R | Guerra, J | Hand, B | Fedde, E | R |
| 7/24/2021 | | @ | Oak | W | 3-0 | | Dunn, J | R | Dunn, J | Hand, B | Anderson, T | L |
| 7/26/2021 | | | LAA | L | 2-4 | | Gray, J | R | Gray, J | | Darvish, Y | R |
| 7/26/2021 | | @ | Tex | W | 4-2 | | Gray, J | R | Gray, J | Hand, B | Fulmer, M | R |
| 7/27/2021 | | | LAA | L | 2-4 | | Ponce de Leon, D | R | Guerra, J | | Toussaint, T | R |
| 7/27/2021 | | @ | Tex | L | 1-6 | | Walker, T | R | Walker, T | | Teheran, J | R |
| 7/28/2021 | | | LAA | W | 2-0 | | Dunn, J | R | Gallegos, G | Hand, B | Bumgarner, M | L |
| 7/28/2021 | | @ | Tex | W | 5-2 | | Ponce de Leon, D | R | Stammen, C | Hand, B | Sanchez, A | R |
| 8/13/2021 | | | Cle | W | 3-1 | | Walker, T | R | Walker, T | Hand, B | Civale, A | R |
| 8/13/2021 | | @ | TB | W | 4-2 | | Hill, R | L | Hill, R | Hand, B | Smeltzer, D | L |
| 8/14/2021 | | | Cle | W | 5-4 | | Ponce de Leon, D | R | Ponce de Leon, D | Hand, B | Bielak, B | R |
| 8/14/2021 | | @ | TB | W | 4-3 | | Smyly, D | L | Smyly, D | Hand, B | Canning, G | R |
| 8/15/2021 | | | Cle | W | 5-0 | | Smyly, D | L | Smyly, D | Matzek, T | Castano, D | L |
| 8/15/2021 | | @ | TB | L | 3-5 | | Gray, J | R | Gray, J | | Anderson, B | L |
| 8/16/2021 | | | KC | L | 1-4 | | Gray, J | R | Guerra, J | | Arrieta, J | R |
| 8/16/2021 | | @ | Tor | W | 5-2 | | Walker, T | R | Walker, T | Heller, B | Velasquez, V | R |
| 8/17/2021 | | | KC | L | 4-7 | | Dunn, J | R | Gallegos, G | | Lindblom, J | R |
| 8/17/2021 | | @ | Tor | L | 4-9 | | Ponce de Leon, D | R | Ponce de Leon, D | | Newcomb, S | L |
| 8/18/2021 | | | KC | W | 1-0 | | Walker, T | R | Matzek, T | Hand, B | Lamet, D | R |
| 8/18/2021 | | @ | Tor | W | 4-0 | | Hill, R | L | Hill, R | | Roark, T | R |
| 8/20/2021 | | | Min | L | 3-6 | | Ponce de Leon, D | R | Ponce de Leon, D | | Urena, J | R |
| 8/20/2021 | | @ | Bos | W | 7-4 | | Smyly, D | L | Smyly, D | Hand, B | Webb, L | R |
| 8/21/2021 | | | Min | W | 5-4 | | Smyly, D | L | Smyly, D | Hand, B | Akin, K | L |
| 8/21/2021 | | @ | Bos | L | 2-6 | | Gray, J | R | Gray, J | | Ynoa, H | R |
| 8/22/2021 | | | Min | L | 3-7 | 17 | Dunn, J | R | Magill, M | | Mahle, T | R |
| 8/22/2021 | | @ | Bos | L | 3-7 | | Walker, T | R | Walker, T | | Plutko, A | R |
| 8/23/2021 | | | ChW | L | 4-10 | | Gray, J | R | Gray, J | | Eovaldi, N | R |
| 8/23/2021 | | @ | NYY | L | 0-2 | | Ponce de Leon, D | R | Ponce de Leon, D | | Bundy, D | R |
| 8/24/2021 | | | ChW | W | 4-0 | | Walker, T | R | Walker, T | | Weaver, L | R |
| 8/24/2021 | | @ | NYY | L | 1-11 | | Hill, R | L | Hill, R | | Lynn, L | R |
| 8/25/2021 | | | ChW | L | 1-5 | | Ponce de Leon, D | R | Ponce de Leon, D | | Tanaka, M | R |
| 8/25/2021 | | @ | NYY | W | 3-0 | | Smyly, D | L | Smyly, D | Hand, B | May, D | R |
| 8/27/2021 | | | Det | L | 0-5 | | Smyly, D | L | Smyly, D | | Marquez, G | R |
| 8/27/2021 | | @ | Bal | L | 1-4 | | Gray, J | R | Gray, J | | Cobb, A | R |
| 8/28/2021 | | | Det | L | 0-13 | | Dunn, J | R | Dunn, J | | Bauer, T | R |
| 8/28/2021 | | @ | Bal | L | 0-8 | | Walker, T | R | Walker, T | | Urias, J | L |
| 8/29/2021 | | | Det | L | 2-8 | | Walker, T | R | Walker, T | | Flaherty, J | R |
| 8/29/2021 | | @ | Bal | L | 1-4 | | Ponce de Leon, D | R | Matzek, T | | Turnbull, S | R |
| 9/13/2021 | | | Oak | W | 2-1 | | Hamels, C | L | Hand, B | | Fried, M | L |
| 9/13/2021 | | @ | Sea | L | 2-5 | | Smyly, D | L | Smyly, D | | Minor, M | L |
| 9/14/2021 | | | Oak | L | 2-4 | 10 | Verlander, J | R | Hand, B | | Scherzer, M | R |
| 9/14/2021 | | @ | Sea | L | 0-3 | | Dunn, J | R | Dunn, J | | Glasnow, T | R |
| 9/15/2021 | | | Oak | L | 2-11 | | Ponce de Leon, D | R | Ponce de Leon, D | | Gibson, K | R |
| 9/15/2021 | | @ | Sea | L | 2-5 | | Hill, R | L | Hill, R | | Skubal, T | L |
| 9/17/2021 | | | LAA | L | 2-3 | 13 | Dunn, J | R | Stammen, C | | Darvish, Y | R |
| 9/17/2021 | | @ | Tex | W | 6-2 | | Walker, T | R | Walker, T | | Stripling, R | R |
| 9/18/2021 | | | LAA | L | 2-7 | | Hamels, C | L | Hamels, C | | Toussaint, T | R |
| 9/18/2021 | | @ | Tex | L | 0-2 | | Gray, J | R | Gray, J | | McKenzie, T | R |
| 9/19/2021 | | | LAA | W | 4-3 | | Verlander, J | R | Matzek, T | | Gomber, A | L |
| 9/19/2021 | | @ | Tex | W | 2-1 | | Smyly, D | L | Smyly, D | Gallegos, G | Eshelman, T | R |
| 9/20/2021 | | | Tex | L | 6-8 | 10 | Ponce de Leon, D | R | Hand, B | | Teheran, J | R |
| 9/20/2021 | | @ | LAA | L | 5-6 | | Dunn, J | R | Guerra, J | | Gomber, A | L |
| 9/21/2021 | | | Tex | L | 3-5 | | Kickham, M | L | Kickham, M | | Sanchez, A | R |
| 9/21/2021 | | @ | LAA | L | 0-3 | | Hill, R | L | Hill, R | | Pineda, M | R |
| 9/22/2021 | | | Tex | L | 2-6 | | Hamels, C | L | Hamels, C | | McKenzie, T | R |
| 9/22/2021 | | @ | LAA | W | 6-5 | | Walker, T | R | Heller, B | Hand, B | Boyd, M | L |
| 9/24/2021 | | | Sea | L | 3-4 | | Dunn, J | R | Guerra, J | | Minor, M | L |
| 9/24/2021 | | @ | Oak | L | 0-5 | | Hamels, C | L | Hamels, C | | Cueto, J | R |
| 9/25/2021 | | | Sea | L | 6-17 | | Verlander, J | R | Verlander, J | | Glasnow, T | R |
| 9/25/2021 | | @ | Oak | W | 4-3 | | Smyly, D | L | Guerra, J | Gallegos, G | Anderson, T | L |
| 9/26/2021 | | | Sea | W | 5-4 | | Kickham, M | L | Matzek, T | Hand, B | Rea, C | R |
| 9/26/2021 | | @ | Oak | L | 3-7 | | Verlander, J | R | Verlander, J | | Dobnak, R | R |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/15/2021 | | | Sea | L | | 2 | 5 | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/15/2021 | | @ | Oak | W | Grossman, R | 3 | 2 | 1 | 1 | .500 | 1-1 | W1 | 2 |
| 4/16/2021 | | | Sea | L | | 4 | 6 | 1 | 2 | .333 | 1-2 | L1 | 3 |
| 4/16/2021 | | @ | Oak | L | | 0 | 1 | 1 | 3 | .250 | 1-3 | L2 | 4 |
| 4/17/2021 | | | Sea | L | | 3 | 9 | 1 | 4 | .200 | 1-4 | L3 | 5 |
| 4/17/2021 | | @ | Oak | W | Braun, R | 6 | 5 | 2 | 4 | .333 | 2-4 | W1 | 6 |
| 4/19/2021 | | | Tex | L | | 3 | 4 | 2 | 5 | .286 | 2-5 | L1 | 7 |
| 4/19/2021 | | @ | LAA | L | | 7 | 13 | 2 | 6 | .250 | 2-6 | L2 | 8 |
| 4/20/2021 | | | Tex | L | | 2 | 3 | 2 | 7 | .222 | 2-7 | L3 | 9 |
| 4/20/2021 | | @ | LAA | L | | 0 | 3 | 2 | 8 | .200 | 2-8 | L4 | 10 |
| 4/21/2021 | | | Tex | W | Story, T | 12 | 11 | 3 | 8 | .273 | 3-7 | W1 | 11 |
| 4/21/2021 | | @ | LAA | L | | 1 | 4 | 3 | 9 | .250 | 2-8 | L1 | 12 |
| 4/22/2021 | | | LAA | W | Grossman, R | 4 | 0 | 4 | 9 | .308 | 3-7 | W1 | 13 |
| 4/22/2021 | | @ | Tex | L | | 3 | 4 | 4 | 10 | .286 | 3-7 | L1 | 14 |
| 4/23/2021 | | | LAA | L | | 5 | 13 | 4 | 11 | .267 | 3-7 | L2 | 15 |
| 4/23/2021 | | @ | Tex | W | Estrada, T | 7 | 2 | 5 | 11 | .313 | 3-7 | W1 | 16 |
| 4/24/2021 | | | LAA | L | | 2 | 3 | 5 | 12 | .294 | 3-7 | L1 | 17 |
| 4/24/2021 | | @ | Tex | L | | 5 | 7 | 5 | 13 | .278 | 3-7 | L2 | 18 |
| 4/26/2021 | | | Oak | W | Davidson, M | 3 | 2 | 6 | 13 | .316 | 4-6 | W1 | 19 |
| 4/26/2021 | | @ | Sea | W | Harper, B | 2 | 1 | 7 | 13 | .350 | 5-5 | W2 | 20 |
| 4/27/2021 | | | Oak | L | | 0 | 6 | 7 | 14 | .333 | 4-6 | L1 | 21 |
| 4/27/2021 | | @ | Sea | L | | 4 | 6 | 7 | 15 | .318 | 4-6 | L2 | 22 |
| 4/28/2021 | | | Oak | L | | 2 | 3 | 7 | 16 | .304 | 3-7 | L3 | 23 |
| 4/28/2021 | | @ | Sea | L | | 2 | 5 | 7 | 17 | .292 | 3-7 | L4 | 24 |
| 5/13/2021 | | | StL | L | | 2 | 7 | 7 | 18 | .280 | 3-7 | L5 | 25 |
| 5/13/2021 | | @ | Phi | L | | 3 | 5 | 7 | 19 | .269 | 2-8 | L6 | 26 |
| 5/14/2021 | | | StL | W | Harper, B | 7 | 1 | 8 | 19 | .296 | 3-7 | W1 | 27 |
| 5/14/2021 | | @ | Phi | W | Harper, B | 3 | 1 | 9 | 19 | .321 | 4-6 | W2 | 28 |
| 5/15/2021 | | | StL | W | Cano, R | 7 | 6 | 10 | 19 | .345 | 4-6 | W3 | 29 |
| 5/15/2021 | | @ | Phi | L | | 3 | 4 | 10 | 20 | .333 | 3-7 | L1 | 30 |
| 5/17/2021 | | @ | Atl | L | | 1 | 2 | 10 | 21 | .323 | 3-7 | L2 | 31 |
| 5/17/2021 | | | Pit | W | Cano, R | 6 | 5 | 11 | 21 | .344 | 4-6 | W1 | 32 |
| 5/18/2021 | | @ | Atl | L | | 3 | 4 | 11 | 22 | .333 | 4-6 | L1 | 33 |
| 5/18/2021 | | | Pit | W | Braun, R | 7 | 1 | 12 | 22 | .353 | 5-5 | W1 | 34 |
| 5/19/2021 | | @ | Atl | W | Story, T | 5 | 1 | 13 | 22 | .371 | 6-4 | W2 | 35 |
| 5/19/2021 | | | Pit | W | Harper, B | 3 | 1 | 14 | 22 | .389 | 7-3 | W3 | 36 |
| 5/21/2021 | | | ChC | W | Story, T | 8 | 3 | 15 | 22 | .405 | 7-3 | W4 | 37 |
| 5/21/2021 | | @ | NYM | W | Cano, R | 6 | 0 | 16 | 22 | .421 | 7-3 | W5 | 38 |
| 5/22/2021 | | | ChC | L | | 1 | 11 | 16 | 23 | .410 | 6-4 | L1 | 39 |
| 5/22/2021 | | @ | NYM | W | Harper, B | 8 | 2 | 17 | 23 | .425 | 7-3 | W1 | 40 |
| 5/23/2021 | | | ChC | L | | 0 | 8 | 17 | 24 | .415 | 7-3 | L1 | 41 |
| 5/23/2021 | | @ | NYM | W | Story, T | 5 | 3 | 18 | 24 | .429 | 7-3 | W1 | 42 |
| 5/24/2021 | | | Cin | L | | 3 | 6 | 18 | 25 | .419 | 7-3 | L1 | 43 |
| 5/24/2021 | | @ | Was | L | | 3 | 4 | 18 | 26 | .409 | 6-4 | L2 | 44 |
| 5/25/2021 | | | Cin | L | | 2 | 6 | 18 | 27 | .400 | 5-5 | L3 | 45 |
| 5/25/2021 | | @ | Was | L | | 1 | 2 | 18 | 28 | .391 | 4-6 | L4 | 46 |
| 5/26/2021 | | | Cin | W | Cano, R | 5 | 4 | 19 | 28 | .404 | 4-6 | W1 | 47 |
| 5/26/2021 | | @ | Was | L | | 4 | 7 | 19 | 29 | .396 | 3-7 | L1 | 48 |
| 5/28/2021 | | | Mil | W | | 3 | 2 | 20 | 29 | .408 | 4-6 | W1 | 49 |
| 5/28/2021 | | @ | Mia | L | | 3 | 5 | 20 | 30 | .400 | 3-7 | L1 | 50 |
| 5/29/2021 | | | Mil | L | | 3 | 11 | 20 | 31 | .392 | 3-7 | L2 | 51 |
| 5/29/2021 | | @ | Mia | L | | 3 | 14 | 20 | 32 | .385 | 2-8 | L3 | 52 |
| 5/30/2021 | | | Mil | W | Harper, B | 7 | 1 | 21 | 32 | .396 | 3-7 | W1 | 53 |
| 5/30/2021 | | @ | Mia | W | Cano, R | 6 | 4 | 22 | 32 | .407 | 4-6 | W2 | 54 |
| 6/14/2021 | | | Bal | L | | 2 | 5 | 22 | 33 | .400 | 4-6 | L1 | 55 |
| 6/14/2021 | | @ | ChW | L | | 4 | 5 | 22 | 34 | .393 | 4-6 | L2 | 56 |
| 6/15/2021 | | | Bal | L | | 2 | 5 | 22 | 35 | .386 | 3-7 | L3 | 57 |
| 6/15/2021 | | @ | ChW | W | Cano, R | 4 | 3 | 23 | 35 | .397 | 4-6 | W1 | 58 |
| 6/16/2021 | | | Bal | W | Dubon, M | 3 | 2 | 24 | 35 | .407 | 4-6 | W2 | 59 |
| 6/16/2021 | | @ | ChW | L | | 5 | 8 | 24 | 36 | .400 | 4-6 | L1 | 60 |
| 6/17/2021 | | | Bos | L | | 0 | 6 | 24 | 37 | .393 | 4-6 | L2 | 61 |
| 6/17/2021 | | @ | Min | L | | 0 | 2 | 24 | 38 | .387 | 4-6 | L3 | 62 |
| 6/18/2021 | | | Bos | L | | 5 | 10 | 24 | 39 | .381 | 3-7 | L4 | 63 |
| 6/18/2021 | | @ | Min | L | | 1 | 2 | 24 | 40 | .375 | 2-8 | L5 | 64 |
| 6/19/2021 | | | Bos | W | Cano, R | 3 | 2 | 25 | 40 | .385 | 3-7 | W1 | 65 |
| 6/19/2021 | | @ | Min | L | | 3 | 7 | 25 | 41 | .379 | 3-7 | L1 | 66 |
| 6/21/2021 | | | NYY | W | Bryant, K | 5 | 2 | 26 | 41 | .388 | 4-6 | W1 | 67 |
| 6/21/2021 | | @ | Cle | L | | 1 | 5 | 26 | 42 | .382 | 3-7 | L1 | 68 |
| 6/22/2021 | | | NYY | W | Story, T | 2 | 1 | 27 | 42 | .391 | 3-7 | W1 | 69 |
| 6/22/2021 | | @ | Cle | L | | 0 | 6 | 27 | 43 | .386 | 3-7 | L1 | 70 |
| 6/23/2021 | | | NYY | W | Cano, R | 6 | 3 | 28 | 43 | .394 | 4-6 | W1 | 71 |
| 6/23/2021 | | @ | Cle | L | | 4 | 11 | 28 | 44 | .389 | 4-6 | L1 | 72 |
| 6/24/2021 | | | TB | L | | 2 | 3 | 28 | 45 | .384 | 4-6 | L2 | 73 |
| 6/24/2021 | | @ | Det | L | | 4 | 5 | 28 | 46 | .378 | 4-6 | L3 | 74 |
| 6/25/2021 | | | TB | W | | 4 | 2 | 29 | 46 | .387 | 4-6 | W1 | 75 |
| 6/25/2021 | | @ | Det | L | | 0 | 1 | 29 | 47 | .382 | 4-6 | L1 | 76 |
| 6/26/2021 | | | TB | W | Estrada, T | 5 | 1 | 30 | 47 | .390 | 4-6 | W1 | 77 |
| 6/26/2021 | | @ | Det | L | | 3 | 4 | 30 | 48 | .385 | 4-6 | L1 | 78 |
| 6/28/2021 | | | Tor | W | Story, T | 9 | 0 | 31 | 48 | .392 | 4-6 | W1 | 79 |
| 6/28/2021 | | @ | KC | L | | 1 | 12 | 31 | 49 | .387 | 4-6 | L1 | 80 |
| 6/29/2021 | | | Tor | W | Story, T | 7 | 2 | 32 | 49 | .395 | 4-6 | W1 | 81 |
| 6/29/2021 | | @ | KC | W | Cano, R | 5 | 0 | 33 | 49 | .402 | 5-5 | W2 | 82 |
| 6/30/2021 | | | Tor | W | Estrada, T | 9 | 2 | 34 | 49 | .410 | 6-4 | W3 | 83 |
| 6/30/2021 | | @ | KC | W | Cano, R | 8 | 5 | 35 | 49 | .417 | 7-3 | W4 | 84 |
| 7/15/2021 | | | Tex | W | Bryant, K | 6 | 4 | 36 | 49 | .424 | 7-3 | W5 | 85 |
| 7/15/2021 | | @ | LAA | W | Stassi, M | 7 | 3 | 37 | 49 | .430 | 8-2 | W6 | 86 |
| 7/16/2021 | | | Tex | L | | 5 | 7 | 37 | 50 | .425 | 7-3 | L1 | 87 |
| 7/16/2021 | | @ | LAA | L | | 3 | 13 | 37 | 51 | .420 | 7-3 | L2 | 88 |
| 7/17/2021 | | | Tex | W | | 4 | 1 | 38 | 51 | .427 | 7-3 | W1 | 89 |
| 7/17/2021 | | @ | LAA | L | | 1 | 4 | 38 | 52 | .422 | 7-3 | L1 | 90 |
| 7/19/2021 | | | Oak | L | | 2 | 5 | 38 | 53 | .418 | 6-4 | L2 | 91 |
| 7/19/2021 | | @ | Sea | L | | 0 | 11 | 38 | 54 | .413 | 5-5 | L3 | 92 |
| 7/20/2021 | | | Oak | L | | 2 | 3 | 38 | 55 | .409 | 4-6 | L4 | 93 |
| 7/20/2021 | | @ | Sea | L | | 2 | 7 | 38 | 56 | .404 | 3-7 | L5 | 94 |
| 7/21/2021 | | | Oak | W | Brown, S | 7 | 4 | 39 | 56 | .411 | 3-7 | W1 | 95 |
| 7/21/2021 | | @ | Sea | L | | 1 | 5 | 39 | 57 | .406 | 2-8 | L1 | 96 |
| 7/22/2021 | | | Sea | L | | 2 | 14 | 39 | 58 | .402 | 2-8 | L2 | 97 |
| 7/22/2021 | | @ | Oak | L | | 2 | 14 | 39 | 59 | .398 | 2-8 | L3 | 98 |
| 7/23/2021 | | | Sea | L | | 0 | 6 | 39 | 60 | .394 | 1-9 | L4 | 99 |
| 7/23/2021 | | @ | Oak | L | | 2 | 8 | 39 | 61 | .390 | 1-9 | L5 | 100 |
| 7/24/2021 | | | Sea | W | Oliva, J | 3 | 2 | 40 | 61 | .396 | 2-8 | W1 | 101 |
| 7/24/2021 | | @ | Oak | W | Story, T | 3 | 0 | 41 | 61 | .402 | 3-7 | W2 | 102 |
| 7/26/2021 | | | LAA | L | | 2 | 4 | 41 | 62 | .398 | 3-7 | L1 | 103 |
| 7/26/2021 | | @ | Tex | W | Bryant, K | 4 | 2 | 42 | 62 | .404 | 4-6 | W1 | 104 |
| 7/27/2021 | | | LAA | L | | 2 | 4 | 42 | 63 | .400 | 3-7 | L1 | 105 |
| 7/27/2021 | | @ | Tex | L | | 1 | 6 | 42 | 64 | .396 | 3-7 | L2 | 106 |
| 7/28/2021 | | | LAA | W | Young, A | 2 | 0 | 43 | 64 | .402 | 4-6 | W1 | 107 |
| 7/28/2021 | | @ | Tex | W | Story, T | 5 | 2 | 44 | 64 | .407 | 5-5 | W2 | 108 |
| 8/13/2021 | | | Cle | W | Harper, B | 3 | 1 | 45 | 64 | .413 | 6-4 | W3 | 109 |
| 8/13/2021 | | @ | TB | W | Stassi, M | 4 | 2 | 46 | 64 | .418 | 7-3 | W4 | 110 |
| 8/14/2021 | | | Cle | W | Murphy, D | 5 | 4 | 47 | 64 | .423 | 7-3 | W5 | 111 |
| 8/14/2021 | | @ | TB | W | Dubon, M | 4 | 3 | 48 | 64 | .429 | 7-3 | W6 | 112 |
| 8/15/2021 | | | Cle | W | Dubon, M | 5 | 0 | 49 | 64 | .434 | 8-2 | W7 | 113 |
| 8/15/2021 | | @ | TB | L | | 3 | 5 | 49 | 65 | .430 | 7-3 | L1 | 114 |
| 8/16/2021 | | | KC | L | | 1 | 4 | 49 | 66 | .426 | 7-3 | L2 | 115 |
| 8/16/2021 | | @ | Tor | W | Estrada, T | 5 | 2 | 50 | 66 | .431 | 8-2 | W1 | 116 |
| 8/17/2021 | | | KC | L | | 4 | 7 | 50 | 67 | .427 | 7-3 | L1 | 117 |
| 8/17/2021 | | @ | Tor | L | | 4 | 9 | 50 | 68 | .424 | 6-4 | L2 | 118 |
| 8/18/2021 | | | KC | W | Barnhart, T | 1 | 0 | 51 | 68 | .429 | 6-4 | W1 | 119 |
| 8/18/2021 | | @ | Tor | W | Story, T | 4 | 0 | 52 | 68 | .433 | 6-4 | W2 | 120 |
| 8/20/2021 | | | Min | L | | 3 | 6 | 52 | 69 | .430 | 5-5 | L1 | 121 |
| 8/20/2021 | | @ | Bos | W | Stassi, M | 7 | 4 | 53 | 69 | .434 | 5-5 | W1 | 122 |
| 8/21/2021 | | | Min | W | Harper, B | 5 | 4 | 54 | 69 | .439 | 5-5 | W2 | 123 |
| 8/21/2021 | | @ | Bos | L | | 2 | 6 | 54 | 70 | .435 | 5-5 | L1 | 124 |
| 8/22/2021 | | | Min | L | | 3 | 7 | 54 | 71 | .432 | 5-5 | L2 | 125 |
| 8/22/2021 | | @ | Bos | L | | 3 | 7 | 54 | 72 | .429 | 4-6 | L3 | 126 |
| 8/23/2021 | | | ChW | L | | 4 | 10 | 54 | 73 | .425 | 4-6 | L4 | 127 |
| 8/23/2021 | | @ | NYY | L | | 0 | 2 | 54 | 74 | .422 | 4-6 | L5 | 128 |
| 8/24/2021 | | | ChW | W | Harper, B | 4 | 0 | 55 | 74 | .426 | 4-6 | W1 | 129 |
| 8/24/2021 | | @ | NYY | L | | 1 | 11 | 55 | 75 | .423 | 3-7 | L1 | 130 |
| 8/25/2021 | | | ChW | L | | 1 | 5 | 55 | 76 | .420 | 3-7 | L2 | 131 |
| 8/25/2021 | | @ | NYY | W | Murphy, D | 3 | 0 | 56 | 76 | .424 | 3-7 | W1 | 132 |
| 8/27/2021 | | | Det | L | | 0 | 5 | 56 | 77 | .421 | 2-8 | L1 | 133 |
| 8/27/2021 | | @ | Bal | L | | 1 | 4 | 56 | 78 | .418 | 2-8 | L2 | 134 |
| 8/28/2021 | | | Det | L | | 0 | 13 | 56 | 79 | .415 | 2-8 | L3 | 135 |
| 8/28/2021 | | @ | Bal | L | | 0 | 8 | 56 | 80 | .412 | 2-8 | L4 | 136 |
| 8/29/2021 | | | Det | L | | 2 | 8 | 56 | 81 | .409 | 2-8 | L5 | 137 |
| 8/29/2021 | | @ | Bal | L | | 1 | 4 | 56 | 82 | .406 | 2-8 | L6 | 138 |
| 9/13/2021 | | | Oak | W | Story, T | 2 | 1 | 57 | 82 | .410 | 2-8 | W1 | 139 |
| 9/13/2021 | | @ | Sea | L | | 2 | 5 | 57 | 83 | .407 | 2-8 | L1 | 140 |
| 9/14/2021 | | | Oak | L | | 2 | 4 | 57 | 84 | .404 | 2-8 | L2 | 141 |
| 9/14/2021 | | @ | Sea | L | | 0 | 3 | 57 | 85 | .401 | 1-9 | L3 | 142 |
| 9/15/2021 | | | Oak | L | | 2 | 11 | 57 | 86 | .399 | 1-9 | L4 | 143 |
| 9/15/2021 | | @ | Sea | L | | 2 | 5 | 57 | 87 | .396 | 1-9 | L5 | 144 |
| 9/17/2021 | | | LAA | L | | 2 | 3 | 57 | 88 | .393 | 1-9 | L6 | 145 |
| 9/17/2021 | | @ | Tex | W | Harper, B | 6 | 2 | 58 | 88 | .397 | 2-8 | W1 | 146 |
| 9/18/2021 | | | LAA | L | | 2 | 7 | 58 | 89 | .395 | 2-8 | L1 | 147 |
| 9/18/2021 | | @ | Tex | L | | 0 | 2 | 58 | 90 | .392 | 2-8 | L2 | 148 |
| 9/19/2021 | | | LAA | W | Dubon, M | 4 | 3 | 59 | 90 | .396 | 2-8 | W1 | 149 |
| 9/19/2021 | | @ | Tex | W | Drury, B | 2 | 1 | 60 | 90 | .400 | 3-7 | W2 | 150 |
| 9/20/2021 | | | Tex | L | | 6 | 8 | 60 | 91 | .397 | 3-7 | L1 | 151 |
| 9/20/2021 | | @ | LAA | L | | 5 | 6 | 60 | 92 | .395 | 3-7 | L2 | 152 |
| 9/21/2021 | | | Tex | L | | 3 | 5 | 60 | 93 | .392 | 3-7 | L3 | 153 |
| 9/21/2021 | | @ | LAA | L | | 0 | 3 | 60 | 94 | .390 | 3-7 | L4 | 154 |
| 9/22/2021 | | | Tex | L | | 2 | 6 | 60 | 95 | .387 | 3-7 | L5 | 155 |
| 9/22/2021 | | @ | LAA | W | Noll, J | 6 | 5 | 61 | 95 | .391 | 3-7 | W1 | 156 |
| 9/24/2021 | | | Sea | L | | 3 | 4 | 61 | 96 | .389 | 3-7 | L1 | 157 |
| 9/24/2021 | | @ | Oak | L | | 0 | 5 | 61 | 97 | .386 | 3-7 | L2 | 158 |
| 9/25/2021 | | | Sea | L | | 6 | 17 | 61 | 98 | .384 | 2-8 | L3 | 159 |
| 9/25/2021 | | @ | Oak | W | Stassi, M | 4 | 3 | 62 | 98 | .387 | 2-8 | W1 | 160 |
| 9/26/2021 | | | Sea | W | Oliva, J | 5 | 4 | 63 | 98 | .391 | 3-7 | W2 | 161 |
| 9/26/2021 | | @ | Oak | L | | 3 | 7 | 63 | 99 | .389 | 3-7 | L1 | 162 |