Team game results - 2021 Cincinnati Reds
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/15/2021 | | | Pit | W | 4-1 | | Woodruff, B | R | Woodruff, B | Rogers, T | Davies, Z | R |
| 4/15/2021 | | @ | Mil | L | 1-2 | 12 | Woodruff, B | R | Stashak, C | | Richards, G | R |
| 4/16/2021 | | | Pit | W | 13-5 | | Berrios, J | R | Berrios, J | Castillo, D | Mize, C | R |
| 4/16/2021 | | @ | Mil | W | 13-7 | | Berrios, J | R | Berrios, J | | Kershaw, C | L |
| 4/17/2021 | | | Pit | W | 7-6 | | Kikuchi, Y | L | Stashak, C | | Senzatela, A | R |
| 4/17/2021 | | @ | Mil | L | 0-10 | | Kikuchi, Y | L | Kikuchi, Y | | Morton, C | R |
| 4/19/2021 | | @ | ChC | W | 10-9 | | Lyles, J | R | Lyles, J | Kline, B | Montas, F | R |
| 4/19/2021 | | | StL | W | 9-1 | | Lyles, J | R | Lyles, J | | Oviedo, J | R |
| 4/20/2021 | | @ | ChC | L | 0-3 | | Woodruff, B | R | Woodruff, B | | Greinke, Z | R |
| 4/20/2021 | | | StL | W | 5-1 | | Woodruff, B | R | Woodruff, B | Rogers, T | Newsome, L | R |
| 4/21/2021 | | @ | ChC | W | 5-4 | | Berrios, J | R | Castillo, D | Stashak, C | Keuchel, D | L |
| 4/21/2021 | | | StL | W | 11-7 | | Berrios, J | R | Lail, B | | Carrasco, C | R |
| 4/22/2021 | | | ChC | L | 4-9 | | Kikuchi, Y | L | Kikuchi, Y | | Greinke, Z | R |
| 4/22/2021 | | @ | StL | W | 5-4 | | Kikuchi, Y | L | Stashak, C | | Ray, R | L |
| 4/23/2021 | | | ChC | L | 7-8 | | Plesac, Z | R | Plesac, Z | | Keuchel, D | L |
| 4/23/2021 | | @ | StL | W | 2-0 | | Plesac, Z | R | Plesac, Z | Kline, B | Paxton, J | L |
| 4/24/2021 | | | ChC | W | 5-4 | | Woodruff, B | R | Woodruff, B | Lugo, S | Montas, F | R |
| 4/24/2021 | | @ | StL | W | 7-4 | | Woodruff, B | R | Woodruff, B | Lail, B | Carrasco, C | R |
| 4/26/2021 | | | Mil | L | 6-14 | | Lyles, J | R | Ramirez, N | | Brault, S | L |
| 4/26/2021 | | @ | Pit | W | 9-3 | | Lyles, J | R | Lyles, J | | Samardzija, J | R |
| 4/27/2021 | | | Mil | W | 7-6 | | Berrios, J | R | Rogers, T | Lugo, S | Morton, C | R |
| 4/27/2021 | | @ | Pit | L | 4-5 | | Berrios, J | R | Castillo, D | | McCullers, L | R |
| 4/28/2021 | | | Mil | L | 5-6 | | Plesac, Z | R | Castillo, D | | Gonsolin, T | R |
| 4/28/2021 | | @ | Pit | W | 4-2 | 10 | Plesac, Z | R | Stashak, C | | Montgomery, J | L |
| 5/13/2021 | | | Bal | L | 1-9 | | Kikuchi, Y | L | Kikuchi, Y | | Cobb, A | R |
| 5/13/2021 | | @ | LAA | W | 5-2 | | Kikuchi, Y | L | Kikuchi, Y | | Gomber, A | L |
| 5/14/2021 | | | Bal | W | 10-3 | | Woodruff, B | R | Woodruff, B | | Turnbull, S | R |
| 5/14/2021 | | @ | LAA | L | 5-7 | | Woodruff, B | R | Castillo, D | | Darvish, Y | R |
| 5/15/2021 | | | Bal | L | 6-7 | | Berrios, J | R | Berrios, J | | Mills, A | R |
| 5/15/2021 | | @ | LAA | L | 1-9 | | Berrios, J | R | Berrios, J | | Yarbrough, R | L |
| 5/17/2021 | | | Bos | L | 1-8 | | Lyles, J | R | Lyles, J | | Javier, C | R |
| 5/17/2021 | | @ | Tex | W | 18-4 | | Lyles, J | R | Lyles, J | | Fulmer, M | R |
| 5/18/2021 | | | Bos | L | 5-13 | | Kikuchi, Y | L | Kikuchi, Y | | Webb, L | R |
| 5/18/2021 | | @ | Tex | W | 9-6 | | Kikuchi, Y | L | Lail, B | Stashak, C | Eshelman, T | R |
| 5/19/2021 | | | Bos | W | 8-3 | | Plesac, Z | R | Plesac, Z | | Medina, A | R |
| 5/19/2021 | | @ | Tex | W | 11-1 | | Plesac, Z | R | Plesac, Z | | Sanchez, A | R |
| 5/21/2021 | | | NYY | W | 6-4 | | Woodruff, B | R | Rogers, T | | Burnes, C | R |
| 5/21/2021 | | @ | Sea | W | 15-2 | | Woodruff, B | R | Woodruff, B | | Minor, M | L |
| 5/22/2021 | | | NYY | L | 0-9 | | Berrios, J | R | Berrios, J | | Bundy, D | R |
| 5/22/2021 | | @ | Sea | W | 5-2 | 13 | Berrios, J | R | Lail, B | | Glasnow, T | R |
| 5/23/2021 | | | NYY | L | 1-2 | | Kikuchi, Y | L | Kikuchi, Y | | May, D | R |
| 5/23/2021 | | @ | Sea | L | 3-4 | | Kikuchi, Y | L | Kikuchi, Y | | Skubal, T | L |
| 5/24/2021 | | | TB | W | 19-4 | | Lyles, J | R | Lyles, J | Lail, B | Lopez, R | R |
| 5/24/2021 | | @ | Hou | W | 6-3 | | Lyles, J | R | Lyles, J | Ramirez, N | Smyly, D | L |
| 5/25/2021 | | | TB | W | 6-0 | | Plesac, Z | R | Plesac, Z | | Canning, G | R |
| 5/25/2021 | | @ | Hou | W | 6-2 | | Plesac, Z | R | Plesac, Z | | Gray, J | R |
| 5/26/2021 | | | TB | W | 19-4 | | Woodruff, B | R | Woodruff, B | | Smeltzer, D | L |
| 5/26/2021 | | @ | Hou | L | 4-5 | 10 | Woodruff, B | R | Lail, B | | Walker, T | R |
| 5/28/2021 | | | Tor | L | 5-6 | | Berrios, J | R | Rogers, T | | Newcomb, S | L |
| 5/28/2021 | | @ | Oak | L | 5-6 | | Berrios, J | R | Berrios, J | | Cueto, J | R |
| 5/29/2021 | | | Tor | W | 16-5 | | Kikuchi, Y | L | Kikuchi, Y | Lail, B | Miley, W | L |
| 5/29/2021 | | @ | Oak | W | 12-0 | | Kikuchi, Y | L | Kikuchi, Y | | Fried, M | L |
| 5/30/2021 | | | Tor | W | 5-1 | | Plesac, Z | R | Plesac, Z | | Roark, T | R |
| 5/30/2021 | | @ | Oak | W | 10-9 | | Plesac, Z | R | Lugo, S | Stashak, C | Anderson, T | L |
| 6/14/2021 | | | SF | W | 5-0 | | Woodruff, B | R | Woodruff, B | | Wheeler, Z | R |
| 6/14/2021 | | @ | Was | W | 3-2 | 11 | Woodruff, B | R | Stashak, C | Castillo, D | Hendricks, K | R |
| 6/15/2021 | | | SF | W | 9-5 | | Berrios, J | R | Berrios, J | | Peterson, D | L |
| 6/15/2021 | | @ | Was | W | 9-4 | | Berrios, J | R | Berrios, J | | Bassitt, C | R |
| 6/16/2021 | | | SF | W | 10-2 | | Kikuchi, Y | L | Kikuchi, Y | | Brice, A | R |
| 6/16/2021 | | @ | Was | L | 7-8 | | Kikuchi, Y | L | Stashak, C | | Gonzales, M | L |
| 6/17/2021 | | | SD | W | 25-8 | | Lyles, J | R | Lyles, J | | Fiers, M | R |
| 6/17/2021 | | @ | Mia | L | 5-9 | | Lyles, J | R | Rogers, T | | Paddack, C | R |
| 6/18/2021 | | | SD | L | 0-5 | | Plesac, Z | R | Plesac, Z | | Giolito, L | R |
| 6/18/2021 | | @ | Mia | W | 5-4 | | Plesac, Z | R | Plesac, Z | | Tomlin, J | R |
| 6/19/2021 | | | SD | L | 3-4 | 14 | Woodruff, B | R | Poppen, S | | Alcantara, S | R |
| 6/19/2021 | | @ | Mia | W | 2-0 | | Woodruff, B | R | Woodruff, B | Stashak, C | Fleming, J | L |
| 6/21/2021 | | | LAD | W | 9-5 | | Berrios, J | R | Stock, R | Lugo, S | Houser, A | R |
| 6/21/2021 | | @ | Phi | W | 4-2 | 13 | Berrios, J | R | Lugo, S | Rogers, T | Sheffield, J | L |
| 6/22/2021 | | | LAD | W | 5-2 | | Kikuchi, Y | L | Kikuchi, Y | Lugo, S | Porcello, R | R |
| 6/22/2021 | | @ | Phi | W | 8-3 | | Kikuchi, Y | L | Kikuchi, Y | Rogers, T | Manaea, S | L |
| 6/23/2021 | | | LAD | L | 4-6 | 10 | Plesac, Z | R | Rogers, T | | Lopez, P | R |
| 6/23/2021 | | @ | Phi | W | 9-4 | | Plesac, Z | R | Plesac, Z | Poppen, S | Hernandez, E | R |
| 6/24/2021 | | @ | Atl | W | 8-5 | | Lyles, J | R | Lyles, J | Stashak, C | Barria, J | R |
| 6/24/2021 | | | Ari | L | 6-9 | 11 | Lyles, J | R | Lugo, S | | Wojciechowski, A | R |
| 6/25/2021 | | @ | Atl | W | 10-8 | | Woodruff, B | R | Woodruff, B | Castillo, D | Corbin, P | L |
| 6/25/2021 | | | Ari | W | 6-2 | | Woodruff, B | R | Woodruff, B | | Gallen, Z | R |
| 6/26/2021 | | @ | Atl | L | 5-10 | | Berrios, J | R | Berrios, J | | Bubic, K | L |
| 6/26/2021 | | | Ari | W | 5-1 | | Berrios, J | R | Ramirez, N | Castillo, D | Ryu, H | L |
| 6/28/2021 | | | Col | L | 5-7 | | Kikuchi, Y | L | Kikuchi, Y | | Means, J | L |
| 6/28/2021 | | @ | NYM | L | 0-6 | | Kikuchi, Y | L | Kikuchi, Y | | Dunning, D | R |
| 6/29/2021 | | | Col | W | 7-6 | | Plesac, Z | R | Rogers, T | Lugo, S | Wainwright, A | R |
| 6/29/2021 | | @ | NYM | W | 5-2 | | Plesac, Z | R | Plesac, Z | | Howard, S | R |
| 6/30/2021 | | | Col | L | 4-10 | | Woodruff, B | R | Woodruff, B | | Godley, Z | R |
| 6/30/2021 | | @ | NYM | L | 3-5 | 10 | Woodruff, B | R | Lugo, S | | Mengden, D | R |
| 7/15/2021 | | @ | ChC | W | 12-8 | | Woodruff, B | R | Woodruff, B | Lugo, S | Keuchel, D | L |
| 7/15/2021 | | | StL | W | 5-0 | | Woodruff, B | R | Woodruff, B | | Ray, R | L |
| 7/16/2021 | | @ | ChC | W | 7-4 | | Berrios, J | R | Berrios, J | Castillo, D | Alzolay, A | R |
| 7/16/2021 | | | StL | W | 7-6 | | Berrios, J | R | Lugo, S | | Carrasco, C | R |
| 7/17/2021 | | @ | ChC | W | 8-4 | | Kikuchi, Y | L | Castillo, D | Stashak, C | Greinke, Z | R |
| 7/17/2021 | | | StL | W | 9-1 | | Kikuchi, Y | L | Kikuchi, Y | | Oviedo, J | R |
| 7/19/2021 | | | Mil | L | 4-9 | | Lyles, J | R | Lyles, J | | Kershaw, C | L |
| 7/19/2021 | | @ | Pit | L | 0-8 | | Lyles, J | R | Lyles, J | | Senzatela, A | R |
| 7/20/2021 | | | Mil | L | 0-4 | | Woodruff, B | R | Woodruff, B | | Slegers, A | R |
| 7/20/2021 | | @ | Pit | W | 8-3 | 11 | Woodruff, B | R | Lugo, S | | McCullers, L | R |
| 7/21/2021 | | | Mil | L | 0-12 | | Berrios, J | R | Berrios, J | | Gonsolin, T | R |
| 7/21/2021 | | @ | Pit | L | 5-7 | | Berrios, J | R | Lugo, S | | Davies, Z | R |
| 7/22/2021 | | | Pit | W | 5-1 | | Kikuchi, Y | L | Kikuchi, Y | | Senzatela, A | R |
| 7/22/2021 | | @ | Mil | L | 3-6 | | Kikuchi, Y | L | Kikuchi, Y | | Morton, C | R |
| 7/23/2021 | | | Pit | L | 5-12 | | Plesac, Z | R | Plesac, Z | | Mize, C | R |
| 7/23/2021 | | @ | Mil | W | 5-0 | | Plesac, Z | R | Plesac, Z | | Brault, S | L |
| 7/24/2021 | | | Pit | W | 7-2 | | Woodruff, B | R | Woodruff, B | Rogers, T | Davies, Z | R |
| 7/24/2021 | | @ | Mil | L | 1-7 | | Woodruff, B | R | Woodruff, B | | Smith, C | L |
| 7/26/2021 | | | ChC | L | 1-2 | | Lyles, J | R | Lyles, J | | Keuchel, D | L |
| 7/26/2021 | | @ | StL | W | 6-1 | | Lyles, J | R | Lyles, J | | Harvey, M | R |
| 7/27/2021 | | | ChC | W | 7-6 | | Berrios, J | R | Berrios, J | | King, M | R |
| 7/27/2021 | | @ | StL | W | 7-4 | | Berrios, J | R | Berrios, J | Stashak, C | Heaney, A | L |
| 7/28/2021 | | | ChC | W | 4-3 | | Plesac, Z | R | Plesac, Z | | Greinke, Z | R |
| 7/28/2021 | | @ | StL | W | 7-2 | | Plesac, Z | R | Plesac, Z | | Paxton, J | L |
| 8/13/2021 | | | Phi | W | 7-6 | 10 | Woodruff, B | R | Lugo, S | | Manaea, S | L |
| 8/13/2021 | | @ | SF | W | 9-2 | | Woodruff, B | R | Woodruff, B | | Wheeler, Z | R |
| 8/14/2021 | | | Phi | W | 7-1 | | Berrios, J | R | Berrios, J | | Castillo, L | R |
| 8/14/2021 | | @ | SF | W | 2-1 | | Berrios, J | R | Berrios, J | Lugo, S | Peterson, D | L |
| 8/15/2021 | | | Phi | W | 9-0 | | Strasburg, S | R | Strasburg, S | Stashak, C | Sheffield, J | L |
| 8/15/2021 | | @ | SF | L | 1-10 | | Strasburg, S | R | Strasburg, S | | Anderson, I | R |
| 8/16/2021 | | | NYM | W | 5-4 | | Plesac, Z | R | Plesac, Z | Lugo, S | Patino, L | R |
| 8/16/2021 | | @ | SD | L | 4-5 | | Plesac, Z | R | Plesac, Z | | Gausman, K | R |
| 8/17/2021 | | | NYM | W | 8-2 | | Lyles, J | R | Lyles, J | | Luzardo, J | L |
| 8/17/2021 | | @ | SD | L | 7-10 | | Lyles, J | R | Lyles, J | | Cease, D | R |
| 8/18/2021 | | | NYM | L | 2-3 | | Woodruff, B | R | Woodruff, B | | Erlin, R | L |
| 8/18/2021 | | @ | SD | L | 5-6 | 10 | Woodruff, B | R | Lugo, S | | Giolito, L | R |
| 8/20/2021 | | | Mia | L | 8-12 | | Berrios, J | R | Berrios, J | | Paddack, C | R |
| 8/20/2021 | | @ | Ari | W | 9-5 | | Berrios, J | R | Castillo, D | | Gray, S | R |
| 8/21/2021 | | | Mia | W | 10-4 | | Strasburg, S | R | Strasburg, S | | Eflin, Z | R |
| 8/21/2021 | | @ | Ari | W | 7-2 | | Strasburg, S | R | Stashak, C | | Ryu, H | L |
| 8/22/2021 | | | Mia | W | 8-1 | | Lyles, J | R | Lyles, J | Guilbeau, T | Tomlin, J | R |
| 8/22/2021 | | @ | Ari | L | 6-12 | | Lyles, J | R | Lyles, J | | Gallen, Z | R |
| 8/23/2021 | | | Was | L | 3-6 | | Plesac, Z | R | Plesac, Z | | Gsellman, R | R |
| 8/23/2021 | | @ | Col | W | 17-8 | | Plesac, Z | R | Plesac, Z | | Mejia, H | R |
| 8/24/2021 | | | Was | L | 4-5 | | Woodruff, B | R | Woodruff, B | | Bassitt, C | R |
| 8/24/2021 | | @ | Col | W | 11-4 | | Woodruff, B | R | Woodruff, B | | Cole, G | R |
| 8/25/2021 | | | Was | W | 9-8 | 12 | Berrios, J | R | Castillo, D | | Gonzales, M | L |
| 8/25/2021 | | @ | Col | L | 5-11 | | Berrios, J | R | Berrios, J | | Means, J | L |
| 8/27/2021 | | | Atl | W | 1-0 | | Strasburg, S | R | Strasburg, S | Lugo, S | Castellani, R | R |
| 8/27/2021 | | @ | LAD | W | 18-3 | | Strasburg, S | R | Stashak, C | Rogers, T | Houser, A | R |
| 8/28/2021 | | | Atl | W | 8-4 | | Lyles, J | R | Lyles, J | | Young, A | L |
| 8/28/2021 | | @ | LAD | L | 13-14 | 12 | Lyles, J | R | Guilbeau, T | | Snell, B | L |
| 8/29/2021 | | | Atl | W | 4-0 | | Woodruff, B | R | Woodruff, B | | LeBlanc, W | L |
| 8/29/2021 | | @ | LAD | L | 5-7 | | Woodruff, B | R | Woodruff, B | | Porcello, R | R |
| 9/13/2021 | | | Mil | W | 1-0 | | Woodruff, B | R | Woodruff, B | Lugo, S | Slegers, A | R |
| 9/13/2021 | | @ | Pit | L | 2-5 | | Strasburg, S | R | Strasburg, S | | Davies, Z | R |
| 9/14/2021 | | | Mil | L | 2-6 | | Berrios, J | R | Berrios, J | | Gonsolin, T | R |
| 9/14/2021 | | @ | Pit | W | 4-2 | | Berrios, J | R | Claudio, A | | Senzatela, A | R |
| 9/15/2021 | | | Mil | L | 6-11 | | Strasburg, S | R | Castillo, D | | Richards, G | R |
| 9/15/2021 | | @ | Pit | W | 11-6 | | Woodruff, B | R | Woodruff, B | | Montgomery, J | L |
| 9/17/2021 | | | ChC | L | 3-6 | | Plesac, Z | R | Plesac, Z | | King, M | R |
| 9/17/2021 | | @ | StL | L | 5-6 | | Lugo, S | R | Lugo, S | | Harvey, M | R |
| 9/18/2021 | | | ChC | W | 4-3 | 10 | Woodruff, B | R | Lugo, S | | Montas, F | R |
| 9/18/2021 | | @ | StL | W | 1-0 | 11 | Strasburg, S | R | Alvarez, J | | Carrasco, C | R |
| 9/19/2021 | | | ChC | L | 3-4 | | Berrios, J | R | Berrios, J | | Greinke, Z | R |
| 9/19/2021 | | @ | StL | L | 2-4 | | Berrios, J | R | Berrios, J | | Heaney, A | L |
| 9/20/2021 | | @ | ChC | L | 1-5 | | Woodruff, B | R | Woodruff, B | | Happ, J | L |
| 9/20/2021 | | | StL | W | 8-3 | | Strasburg, S | R | Strasburg, S | | Heaney, A | L |
| 9/21/2021 | | @ | ChC | W | 5-4 | | Lyles, J | R | Tarpley, S | Rogers, T | Montas, F | R |
| 9/21/2021 | | | StL | W | 11-4 | | Lyles, J | R | Lyles, J | | Newsome, L | R |
| 9/22/2021 | | @ | ChC | W | 8-4 | | Strasburg, S | R | Goody, N | | Keuchel, D | L |
| 9/22/2021 | | | StL | L | 7-8 | | Lugo, S | R | Claudio, A | | Oviedo, J | R |
| 9/24/2021 | | | Pit | W | 4-3 | | Plesac, Z | R | Plesac, Z | Lugo, S | Montgomery, J | L |
| 9/24/2021 | | @ | Mil | L | 1-7 | | Lugo, S | R | Lugo, S | | Kershaw, C | L |
| 9/25/2021 | | | Pit | W | 7-0 | | Berrios, J | R | Berrios, J | Rogers, T | Senzatela, A | R |
| 9/25/2021 | | @ | Mil | L | 0-9 | | Berrios, J | R | Berrios, J | | Gonsolin, T | R |
| 9/26/2021 | | | Pit | L | 3-4 | 10 | Lyles, J | R | Lugo, S | | McCullers, L | R |
| 9/26/2021 | | @ | Mil | L | 1-10 | | Lyles, J | R | Lyles, J | | Brault, S | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/15/2021 | | | Pit | W | | 4 | 1 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/15/2021 | | @ | Mil | L | | 1 | 2 | 1 | 1 | .500 | 1-1 | L1 | 2 |
| 4/16/2021 | | | Pit | W | Frazier, C | 13 | 5 | 2 | 1 | .667 | 2-1 | W1 | 3 |
| 4/16/2021 | | @ | Mil | W | Urshela, G | 13 | 7 | 3 | 1 | .750 | 3-1 | W2 | 4 |
| 4/17/2021 | | | Pit | W | Frazier, C | 7 | 6 | 4 | 1 | .800 | 4-1 | W3 | 5 |
| 4/17/2021 | | @ | Mil | L | | 0 | 10 | 4 | 2 | .667 | 4-2 | L1 | 6 |
| 4/19/2021 | | @ | ChC | W | Molina, Y | 10 | 9 | 5 | 2 | .714 | 5-2 | W1 | 7 |
| 4/19/2021 | | | StL | W | Tatis, F | 9 | 1 | 6 | 2 | .750 | 6-2 | W2 | 8 |
| 4/20/2021 | | @ | ChC | L | | 0 | 3 | 6 | 3 | .667 | 6-3 | L1 | 9 |
| 4/20/2021 | | | StL | W | Aquino, A | 5 | 1 | 7 | 3 | .700 | 7-3 | W1 | 10 |
| 4/21/2021 | | @ | ChC | W | Acuna, R | 5 | 4 | 8 | 3 | .727 | 7-3 | W2 | 11 |
| 4/21/2021 | | | StL | W | Aquino, A | 11 | 7 | 9 | 3 | .750 | 8-2 | W3 | 12 |
| 4/22/2021 | | | ChC | L | | 4 | 9 | 9 | 4 | .692 | 7-3 | L1 | 13 |
| 4/22/2021 | | @ | StL | W | Frazier, C | 5 | 4 | 10 | 4 | .714 | 7-3 | W1 | 14 |
| 4/23/2021 | | | ChC | L | | 7 | 8 | 10 | 5 | .667 | 6-4 | L1 | 15 |
| 4/23/2021 | | @ | StL | W | Locastro, T | 2 | 0 | 11 | 5 | .688 | 7-3 | W1 | 16 |
| 4/24/2021 | | | ChC | W | | 5 | 4 | 12 | 5 | .706 | 7-3 | W2 | 17 |
| 4/24/2021 | | @ | StL | W | Acuna, R | 7 | 4 | 13 | 5 | .722 | 7-3 | W3 | 18 |
| 4/26/2021 | | | Mil | L | | 6 | 14 | 13 | 6 | .684 | 7-3 | L1 | 19 |
| 4/26/2021 | | @ | Pit | W | Frazier, C | 9 | 3 | 14 | 6 | .700 | 7-3 | W1 | 20 |
| 4/27/2021 | | | Mil | W | Tatis, F | 7 | 6 | 15 | 6 | .714 | 7-3 | W2 | 21 |
| 4/27/2021 | | @ | Pit | L | | 4 | 5 | 15 | 7 | .682 | 6-4 | L1 | 22 |
| 4/28/2021 | | | Mil | L | | 5 | 6 | 15 | 8 | .652 | 6-4 | L2 | 23 |
| 4/28/2021 | | @ | Pit | W | Frazier, C | 4 | 2 | 16 | 8 | .667 | 6-4 | W1 | 24 |
| 5/13/2021 | | | Bal | L | | 1 | 9 | 16 | 9 | .640 | 6-4 | L1 | 25 |
| 5/13/2021 | | @ | LAA | W | Tatis, F | 5 | 2 | 17 | 9 | .654 | 6-4 | W1 | 26 |
| 5/14/2021 | | | Bal | W | Tatis, F | 10 | 3 | 18 | 9 | .667 | 6-4 | W2 | 27 |
| 5/14/2021 | | @ | LAA | L | | 5 | 7 | 18 | 10 | .643 | 5-5 | L1 | 28 |
| 5/15/2021 | | | Bal | L | | 6 | 7 | 18 | 11 | .621 | 5-5 | L2 | 29 |
| 5/15/2021 | | @ | LAA | L | | 1 | 9 | 18 | 12 | .600 | 4-6 | L3 | 30 |
| 5/17/2021 | | | Bos | L | | 1 | 8 | 18 | 13 | .581 | 3-7 | L4 | 31 |
| 5/17/2021 | | @ | Tex | W | | 18 | 4 | 19 | 13 | .594 | 4-6 | W1 | 32 |
| 5/18/2021 | | | Bos | L | | 5 | 13 | 19 | 14 | .576 | 4-6 | L1 | 33 |
| 5/18/2021 | | @ | Tex | W | Tatis, F | 9 | 6 | 20 | 14 | .588 | 4-6 | W1 | 34 |
| 5/19/2021 | | | Bos | W | Urshela, G | 8 | 3 | 21 | 14 | .600 | 5-5 | W2 | 35 |
| 5/19/2021 | | @ | Tex | W | Acuna, R | 11 | 1 | 22 | 14 | .611 | 5-5 | W3 | 36 |
| 5/21/2021 | | | NYY | W | Tellez, R | 6 | 4 | 23 | 14 | .622 | 5-5 | W4 | 37 |
| 5/21/2021 | | @ | Sea | W | Mondesi, A | 15 | 2 | 24 | 14 | .632 | 6-4 | W5 | 38 |
| 5/22/2021 | | | NYY | L | | 0 | 9 | 24 | 15 | .615 | 6-4 | L1 | 39 |
| 5/22/2021 | | @ | Sea | W | Tatis, F | 5 | 2 | 25 | 15 | .625 | 7-3 | W1 | 40 |
| 5/23/2021 | | | NYY | L | | 1 | 2 | 25 | 16 | .610 | 7-3 | L1 | 41 |
| 5/23/2021 | | @ | Sea | L | | 3 | 4 | 25 | 17 | .595 | 6-4 | L2 | 42 |
| 5/24/2021 | | | TB | W | Tellez, R | 19 | 4 | 26 | 17 | .605 | 7-3 | W1 | 43 |
| 5/24/2021 | | @ | Hou | W | Tatis, F | 6 | 3 | 27 | 17 | .614 | 7-3 | W2 | 44 |
| 5/25/2021 | | | TB | W | Frazier, C | 6 | 0 | 28 | 17 | .622 | 7-3 | W3 | 45 |
| 5/25/2021 | | @ | Hou | W | Tellez, R | 6 | 2 | 29 | 17 | .630 | 7-3 | W4 | 46 |
| 5/26/2021 | | | TB | W | Mondesi, A | 19 | 4 | 30 | 17 | .638 | 7-3 | W5 | 47 |
| 5/26/2021 | | @ | Hou | L | | 4 | 5 | 30 | 18 | .625 | 6-4 | L1 | 48 |
| 5/28/2021 | | | Tor | L | | 5 | 6 | 30 | 19 | .612 | 6-4 | L2 | 49 |
| 5/28/2021 | | @ | Oak | L | | 5 | 6 | 30 | 20 | .600 | 5-5 | L3 | 50 |
| 5/29/2021 | | | Tor | W | Locastro, T | 16 | 5 | 31 | 20 | .608 | 6-4 | W1 | 51 |
| 5/29/2021 | | @ | Oak | W | Tellez, R | 12 | 0 | 32 | 20 | .615 | 7-3 | W2 | 52 |
| 5/30/2021 | | | Tor | W | Frazier, C | 5 | 1 | 33 | 20 | .623 | 7-3 | W3 | 53 |
| 5/30/2021 | | @ | Oak | W | Tellez, R | 10 | 9 | 34 | 20 | .630 | 7-3 | W4 | 54 |
| 6/14/2021 | | | SF | W | Tellez, R | 5 | 0 | 35 | 20 | .636 | 7-3 | W5 | 55 |
| 6/14/2021 | | @ | Was | W | Molina, Y | 3 | 2 | 36 | 20 | .643 | 7-3 | W6 | 56 |
| 6/15/2021 | | | SF | W | Tatis, F | 9 | 5 | 37 | 20 | .649 | 7-3 | W7 | 57 |
| 6/15/2021 | | @ | Was | W | Acuna, R | 9 | 4 | 38 | 20 | .655 | 8-2 | W8 | 58 |
| 6/16/2021 | | | SF | W | Urshela, G | 10 | 2 | 39 | 20 | .661 | 9-1 | W9 | 59 |
| 6/16/2021 | | @ | Was | L | | 7 | 8 | 39 | 21 | .650 | 9-1 | L1 | 60 |
| 6/17/2021 | | | SD | W | Tatis, F | 25 | 8 | 40 | 21 | .656 | 9-1 | W1 | 61 |
| 6/17/2021 | | @ | Mia | L | | 5 | 9 | 40 | 22 | .645 | 8-2 | L1 | 62 |
| 6/18/2021 | | | SD | L | | 0 | 5 | 40 | 23 | .635 | 7-3 | L2 | 63 |
| 6/18/2021 | | @ | Mia | W | Acuna, R | 5 | 4 | 41 | 23 | .641 | 7-3 | W1 | 64 |
| 6/19/2021 | | | SD | L | | 3 | 4 | 41 | 24 | .631 | 6-4 | L1 | 65 |
| 6/19/2021 | | @ | Mia | W | Marte, K | 2 | 0 | 42 | 24 | .636 | 6-4 | W1 | 66 |
| 6/21/2021 | | | LAD | W | Marte, K | 9 | 5 | 43 | 24 | .642 | 6-4 | W2 | 67 |
| 6/21/2021 | | @ | Phi | W | Tatis, F | 4 | 2 | 44 | 24 | .647 | 6-4 | W3 | 68 |
| 6/22/2021 | | | LAD | W | Tatis, F | 5 | 2 | 45 | 24 | .652 | 6-4 | W4 | 69 |
| 6/22/2021 | | @ | Phi | W | Tellez, R | 8 | 3 | 46 | 24 | .657 | 7-3 | W5 | 70 |
| 6/23/2021 | | | LAD | L | | 4 | 6 | 46 | 25 | .648 | 6-4 | L1 | 71 |
| 6/23/2021 | | @ | Phi | W | Urshela, G | 9 | 4 | 47 | 25 | .653 | 7-3 | W1 | 72 |
| 6/24/2021 | | @ | Atl | W | Locastro, T | 8 | 5 | 48 | 25 | .658 | 8-2 | W2 | 73 |
| 6/24/2021 | | | Ari | L | | 6 | 9 | 48 | 26 | .649 | 7-3 | L1 | 74 |
| 6/25/2021 | | @ | Atl | W | Locastro, T | 10 | 8 | 49 | 26 | .653 | 8-2 | W1 | 75 |
| 6/25/2021 | | | Ari | W | Marte, K | 6 | 2 | 50 | 26 | .658 | 8-2 | W2 | 76 |
| 6/26/2021 | | @ | Atl | L | | 5 | 10 | 50 | 27 | .649 | 7-3 | L1 | 77 |
| 6/26/2021 | | | Ari | W | Acuna, R | 5 | 1 | 51 | 27 | .654 | 7-3 | W1 | 78 |
| 6/28/2021 | | | Col | L | | 5 | 7 | 51 | 28 | .646 | 6-4 | L1 | 79 |
| 6/28/2021 | | @ | NYM | L | | 0 | 6 | 51 | 29 | .637 | 5-5 | L2 | 80 |
| 6/29/2021 | | | Col | W | Tatis, F | 7 | 6 | 52 | 29 | .642 | 6-4 | W1 | 81 |
| 6/29/2021 | | @ | NYM | W | Aquino, A | 5 | 2 | 53 | 29 | .646 | 6-4 | W2 | 82 |
| 6/30/2021 | | | Col | L | | 4 | 10 | 53 | 30 | .639 | 5-5 | L1 | 83 |
| 6/30/2021 | | @ | NYM | L | | 3 | 5 | 53 | 31 | .631 | 5-5 | L2 | 84 |
| 7/15/2021 | | @ | ChC | W | Tatis, F | 12 | 8 | 54 | 31 | .635 | 5-5 | W1 | 85 |
| 7/15/2021 | | | StL | W | Tellez, R | 5 | 0 | 55 | 31 | .640 | 5-5 | W2 | 86 |
| 7/16/2021 | | @ | ChC | W | Acuna, R | 7 | 4 | 56 | 31 | .644 | 6-4 | W3 | 87 |
| 7/16/2021 | | | StL | W | Braun, R | 7 | 6 | 57 | 31 | .648 | 6-4 | W4 | 88 |
| 7/17/2021 | | @ | ChC | W | | 8 | 4 | 58 | 31 | .652 | 7-3 | W5 | 89 |
| 7/17/2021 | | | StL | W | Frazier, C | 9 | 1 | 59 | 31 | .656 | 8-2 | W6 | 90 |
| 7/19/2021 | | | Mil | L | | 4 | 9 | 59 | 32 | .648 | 7-3 | L1 | 91 |
| 7/19/2021 | | @ | Pit | L | | 0 | 8 | 59 | 33 | .641 | 6-4 | L2 | 92 |
| 7/20/2021 | | | Mil | L | | 0 | 4 | 59 | 34 | .634 | 6-4 | L3 | 93 |
| 7/20/2021 | | @ | Pit | W | Tatis, F | 8 | 3 | 60 | 34 | .638 | 7-3 | W1 | 94 |
| 7/21/2021 | | | Mil | L | | 0 | 12 | 60 | 35 | .632 | 6-4 | L1 | 95 |
| 7/21/2021 | | @ | Pit | L | | 5 | 7 | 60 | 36 | .625 | 5-5 | L2 | 96 |
| 7/22/2021 | | | Pit | W | Mondesi, A | 5 | 1 | 61 | 36 | .629 | 5-5 | W1 | 97 |
| 7/22/2021 | | @ | Mil | L | | 3 | 6 | 61 | 37 | .622 | 4-6 | L1 | 98 |
| 7/23/2021 | | | Pit | L | | 5 | 12 | 61 | 38 | .616 | 3-7 | L2 | 99 |
| 7/23/2021 | | @ | Mil | W | Braun, R | 5 | 0 | 62 | 38 | .620 | 3-7 | W1 | 100 |
| 7/24/2021 | | | Pit | W | Tellez, R | 7 | 2 | 63 | 38 | .624 | 4-6 | W2 | 101 |
| 7/24/2021 | | @ | Mil | L | | 1 | 7 | 63 | 39 | .618 | 4-6 | L1 | 102 |
| 7/26/2021 | | | ChC | L | | 1 | 2 | 63 | 40 | .612 | 4-6 | L2 | 103 |
| 7/26/2021 | | @ | StL | W | Urshela, G | 6 | 1 | 64 | 40 | .615 | 4-6 | W1 | 104 |
| 7/27/2021 | | | ChC | W | Acuna, R | 7 | 6 | 65 | 40 | .619 | 5-5 | W2 | 105 |
| 7/27/2021 | | @ | StL | W | Frazier, C | 7 | 4 | 66 | 40 | .623 | 6-4 | W3 | 106 |
| 7/28/2021 | | | ChC | W | Acuna, R | 4 | 3 | 67 | 40 | .626 | 6-4 | W4 | 107 |
| 7/28/2021 | | @ | StL | W | Braun, R | 7 | 2 | 68 | 40 | .630 | 7-3 | W5 | 108 |
| 8/13/2021 | | | Phi | W | Molina, Y | 7 | 6 | 69 | 40 | .633 | 8-2 | W6 | 109 |
| 8/13/2021 | | @ | SF | W | Shaw, T | 9 | 2 | 70 | 40 | .636 | 8-2 | W7 | 110 |
| 8/14/2021 | | | Phi | W | Urshela, G | 7 | 1 | 71 | 40 | .640 | 8-2 | W8 | 111 |
| 8/14/2021 | | @ | SF | W | Braun, R | 2 | 1 | 72 | 40 | .643 | 9-1 | W9 | 112 |
| 8/15/2021 | | | Phi | W | Tatis, F | 9 | 0 | 73 | 40 | .646 | 10-0 | W10 | 113 |
| 8/15/2021 | | @ | SF | L | | 1 | 10 | 73 | 41 | .640 | 9-1 | L1 | 114 |
| 8/16/2021 | | | NYM | W | Shaw, T | 5 | 4 | 74 | 41 | .643 | 9-1 | W1 | 115 |
| 8/16/2021 | | @ | SD | L | | 4 | 5 | 74 | 42 | .638 | 8-2 | L1 | 116 |
| 8/17/2021 | | | NYM | W | Garver, M | 8 | 2 | 75 | 42 | .641 | 8-2 | W1 | 117 |
| 8/17/2021 | | @ | SD | L | | 7 | 10 | 75 | 43 | .636 | 7-3 | L1 | 118 |
| 8/18/2021 | | | NYM | L | | 2 | 3 | 75 | 44 | .630 | 6-4 | L2 | 119 |
| 8/18/2021 | | @ | SD | L | | 5 | 6 | 75 | 45 | .625 | 5-5 | L3 | 120 |
| 8/20/2021 | | | Mia | L | | 8 | 12 | 75 | 46 | .620 | 4-6 | L4 | 121 |
| 8/20/2021 | | @ | Ari | W | McMahon, R | 9 | 5 | 76 | 46 | .623 | 4-6 | W1 | 122 |
| 8/21/2021 | | | Mia | W | Urshela, G | 10 | 4 | 77 | 46 | .626 | 4-6 | W2 | 123 |
| 8/21/2021 | | @ | Ari | W | Shaw, T | 7 | 2 | 78 | 46 | .629 | 5-5 | W3 | 124 |
| 8/22/2021 | | | Mia | W | Urshela, G | 8 | 1 | 79 | 46 | .632 | 5-5 | W4 | 125 |
| 8/22/2021 | | @ | Ari | L | | 6 | 12 | 79 | 47 | .627 | 5-5 | L1 | 126 |
| 8/23/2021 | | | Was | L | | 3 | 6 | 79 | 48 | .622 | 4-6 | L2 | 127 |
| 8/23/2021 | | @ | Col | W | Molina, Y | 17 | 8 | 80 | 48 | .625 | 5-5 | W1 | 128 |
| 8/24/2021 | | | Was | L | | 4 | 5 | 80 | 49 | .620 | 5-5 | L1 | 129 |
| 8/24/2021 | | @ | Col | W | Molina, Y | 11 | 4 | 81 | 49 | .623 | 6-4 | W1 | 130 |
| 8/25/2021 | | | Was | W | Molina, Y | 9 | 8 | 82 | 49 | .626 | 7-3 | W2 | 131 |
| 8/25/2021 | | @ | Col | L | | 5 | 11 | 82 | 50 | .621 | 6-4 | L1 | 132 |
| 8/27/2021 | | | Atl | W | Vargas, I | 1 | 0 | 83 | 50 | .624 | 6-4 | W1 | 133 |
| 8/27/2021 | | @ | LAD | W | Molina, Y | 18 | 3 | 84 | 50 | .627 | 6-4 | W2 | 134 |
| 8/28/2021 | | | Atl | W | Tatis, F | 8 | 4 | 85 | 50 | .630 | 6-4 | W3 | 135 |
| 8/28/2021 | | @ | LAD | L | | 13 | 14 | 85 | 51 | .625 | 6-4 | L1 | 136 |
| 8/29/2021 | | | Atl | W | Mondesi, A | 4 | 0 | 86 | 51 | .628 | 7-3 | W1 | 137 |
| 8/29/2021 | | @ | LAD | L | | 5 | 7 | 86 | 52 | .623 | 6-4 | L1 | 138 |
| 9/13/2021 | | | Mil | W | Acuna, R | 1 | 0 | 87 | 52 | .626 | 7-3 | W1 | 139 |
| 9/13/2021 | | @ | Pit | L | | 2 | 5 | 87 | 53 | .621 | 6-4 | L1 | 140 |
| 9/14/2021 | | | Mil | L | | 2 | 6 | 87 | 54 | .617 | 5-5 | L2 | 141 |
| 9/14/2021 | | @ | Pit | W | Braun, R | 4 | 2 | 88 | 54 | .620 | 6-4 | W1 | 142 |
| 9/15/2021 | | | Mil | L | | 6 | 11 | 88 | 55 | .615 | 5-5 | L1 | 143 |
| 9/15/2021 | | @ | Pit | W | Shaw, T | 11 | 6 | 89 | 55 | .618 | 5-5 | W1 | 144 |
| 9/17/2021 | | | ChC | L | | 3 | 6 | 89 | 56 | .614 | 4-6 | L1 | 145 |
| 9/17/2021 | | @ | StL | L | | 5 | 6 | 89 | 57 | .610 | 4-6 | L2 | 146 |
| 9/18/2021 | | | ChC | W | Tatis, F | 4 | 3 | 90 | 57 | .612 | 4-6 | W1 | 147 |
| 9/18/2021 | | @ | StL | W | Braun, R | 1 | 0 | 91 | 57 | .615 | 5-5 | W2 | 148 |
| 9/19/2021 | | | ChC | L | | 3 | 4 | 91 | 58 | .611 | 4-6 | L1 | 149 |
| 9/19/2021 | | @ | StL | L | | 2 | 4 | 91 | 59 | .607 | 4-6 | L2 | 150 |
| 9/20/2021 | | @ | ChC | L | | 1 | 5 | 91 | 60 | .603 | 4-6 | L3 | 151 |
| 9/20/2021 | | | StL | W | Braun, R | 8 | 3 | 92 | 60 | .605 | 4-6 | W1 | 152 |
| 9/21/2021 | | @ | ChC | W | McMahon, R | 5 | 4 | 93 | 60 | .608 | 5-5 | W2 | 153 |
| 9/21/2021 | | | StL | W | McMahon, R | 11 | 4 | 94 | 60 | .610 | 5-5 | W3 | 154 |
| 9/22/2021 | | @ | ChC | W | Tatis, F | 8 | 4 | 95 | 60 | .613 | 6-4 | W4 | 155 |
| 9/22/2021 | | | StL | L | | 7 | 8 | 95 | 61 | .609 | 6-4 | L1 | 156 |
| 9/24/2021 | | | Pit | W | Shaw, T | 4 | 3 | 96 | 61 | .611 | 6-4 | W1 | 157 |
| 9/24/2021 | | @ | Mil | L | | 1 | 7 | 96 | 62 | .608 | 5-5 | L1 | 158 |
| 9/25/2021 | | | Pit | W | | 7 | 0 | 97 | 62 | .610 | 6-4 | W1 | 159 |
| 9/25/2021 | | @ | Mil | L | | 0 | 9 | 97 | 63 | .606 | 6-4 | L1 | 160 |
| 9/26/2021 | | | Pit | L | | 3 | 4 | 97 | 64 | .602 | 6-4 | L2 | 161 |
| 9/26/2021 | | @ | Mil | L | | 1 | 10 | 97 | 65 | .599 | 5-5 | L3 | 162 |