Team game results - 2021 Chicago Cubs
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/15/2021 | | | Mil | L | 2-4 | | Greinke, Z | R | Greinke, Z | | Gonsolin, T | R |
| 4/15/2021 | | @ | StL | W | 6-5 | | Montas, F | R | Montas, F | Rosenthal, T | Carrasco, C | R |
| 4/16/2021 | | | Mil | L | 2-5 | | Keuchel, D | L | Keuchel, D | | Kershaw, C | L |
| 4/16/2021 | | @ | StL | W | 2-1 | 11 | Happ, J | L | Gant, J | | Heaney, A | L |
| 4/17/2021 | | | Mil | W | 8-6 | | Happ, J | L | Scott, T | Bummer, A | Smith, C | L |
| 4/17/2021 | | @ | StL | W | 7-6 | | Greinke, Z | R | Treinen, B | Romano, J | Ray, R | L |
| 4/19/2021 | | | Cin | L | 9-10 | | Montas, F | R | Montas, F | | Lyles, J | R |
| 4/19/2021 | | @ | Pit | W | 13-4 | | Keuchel, D | L | Keuchel, D | | Samardzija, J | R |
| 4/20/2021 | | | Cin | W | 3-0 | | Greinke, Z | R | Greinke, Z | Bummer, A | Woodruff, B | R |
| 4/20/2021 | | @ | Pit | L | 3-5 | | Montas, F | R | Montas, F | | Davies, Z | R |
| 4/21/2021 | | | Cin | L | 4-5 | | Keuchel, D | L | Rosenthal, T | | Berrios, J | R |
| 4/21/2021 | | @ | Pit | W | 4-3 | | Happ, J | L | Happ, J | Romano, J | McCullers, L | R |
| 4/22/2021 | | | Pit | L | 1-3 | | Happ, J | L | Happ, J | | Senzatela, A | R |
| 4/22/2021 | | @ | Cin | W | 9-4 | | Greinke, Z | R | Greinke, Z | | Kikuchi, Y | L |
| 4/23/2021 | | | Pit | W | 4-3 | | Alzolay, A | R | Rosenthal, T | Bummer, A | McCullers, L | R |
| 4/23/2021 | | @ | Cin | W | 8-7 | | Keuchel, D | L | Keuchel, D | Romano, J | Plesac, Z | R |
| 4/24/2021 | | | Pit | W | 9-3 | | Greinke, Z | R | Greinke, Z | Scott, T | Samardzija, J | R |
| 4/24/2021 | | @ | Cin | L | 4-5 | | Montas, F | R | Treinen, B | | Woodruff, B | R |
| 4/26/2021 | | | StL | W | 7-6 | 11 | Montas, F | R | Treinen, B | | Newsome, L | R |
| 4/26/2021 | | @ | Mil | L | 0-1 | | Happ, J | L | Happ, J | | Gonsolin, T | R |
| 4/27/2021 | | | StL | W | 6-5 | | Keuchel, D | L | Rosenthal, T | | Carrasco, C | R |
| 4/27/2021 | | @ | Mil | W | 3-1 | | Greinke, Z | R | Greinke, Z | Rosenthal, T | Kershaw, C | L |
| 4/28/2021 | | | StL | W | 2-1 | | Alzolay, A | R | Rosenthal, T | | Heaney, A | L |
| 4/28/2021 | | @ | Mil | L | 1-8 | | Keuchel, D | L | Keuchel, D | | Brault, S | L |
| 5/13/2021 | | | TB | W | 10-2 | | Happ, J | L | Happ, J | | Canning, G | R |
| 5/13/2021 | | @ | Tex | W | 4-1 | | King, M | R | King, M | Romano, J | Sanchez, A | R |
| 5/14/2021 | | | TB | W | 5-4 | | Greinke, Z | R | Greinke, Z | Bummer, A | Smeltzer, D | L |
| 5/14/2021 | | @ | Tex | L | 7-8 | | Montas, F | R | May, T | | Thorpe, L | L |
| 5/15/2021 | | | TB | W | 14-3 | | Keuchel, D | L | Keuchel, D | | Anderson, B | L |
| 5/15/2021 | | @ | Tex | W | 16-2 | | Happ, J | L | Happ, J | | Eshelman, T | R |
| 5/17/2021 | | | Tor | W | 9-5 | | Montas, F | R | Treinen, B | | Velasquez, V | R |
| 5/17/2021 | | @ | Sea | L | 1-3 | | Greinke, Z | R | Greinke, Z | | Urquidy, J | R |
| 5/18/2021 | | | Tor | L | 3-7 | | Happ, J | L | Happ, J | | Miley, W | L |
| 5/18/2021 | | @ | Sea | W | 7-2 | | Keuchel, D | L | Keuchel, D | | Skubal, T | L |
| 5/19/2021 | | | Tor | W | 5-3 | | Greinke, Z | R | Greinke, Z | May, T | Roark, T | R |
| 5/19/2021 | | @ | Sea | L | 7-20 | | King, M | R | King, M | | Fedde, E | R |
| 5/21/2021 | | | Bal | L | 8-12 | | Greinke, Z | R | Greinke, Z | | Turnbull, S | R |
| 5/21/2021 | | @ | Hou | L | 3-8 | | Montas, F | R | Montas, F | | Walker, T | R |
| 5/22/2021 | | | Bal | L | 0-1 | | Keuchel, D | L | Keuchel, D | | Mills, A | R |
| 5/22/2021 | | @ | Hou | W | 11-1 | | Happ, J | L | Happ, J | | Dunn, J | R |
| 5/23/2021 | | | Bal | W | 5-2 | | Happ, J | L | Happ, J | Bummer, A | Urias, J | L |
| 5/23/2021 | | @ | Hou | W | 8-0 | | Greinke, Z | R | Greinke, Z | | Hill, R | L |
| 5/24/2021 | | | Bos | L | 5-6 | | Montas, F | R | Montas, F | | Merryweather, J | R |
| 5/24/2021 | | @ | Oak | L | 3-7 | | Keuchel, D | L | Gant, J | | Dobnak, R | R |
| 5/25/2021 | | | Bos | W | 4-2 | | Alzolay, A | R | Alzolay, A | Bummer, A | Plutko, A | R |
| 5/25/2021 | | @ | Oak | L | 4-7 | | King, M | R | King, M | | Anderson, T | L |
| 5/26/2021 | | | Bos | L | 6-9 | | Greinke, Z | R | Greinke, Z | | Hudson, D | R |
| 5/26/2021 | | @ | Oak | W | 2-1 | | Montas, F | R | Montas, F | Romano, J | Scherzer, M | R |
| 5/28/2021 | | | NYY | W | 5-3 | | Keuchel, D | L | Keuchel, D | Bummer, A | Bundy, D | R |
| 5/28/2021 | | @ | LAA | W | 4-3 | | Happ, J | L | Happ, J | Rosenthal, T | Yarbrough, R | L |
| 5/29/2021 | | | NYY | W | 6-5 | | Happ, J | L | Treinen, B | Bummer, A | May, D | R |
| 5/29/2021 | | @ | LAA | L | 2-7 | | Greinke, Z | R | Greinke, Z | | Gomber, A | L |
| 5/30/2021 | | | NYY | L | 2-3 | | Alzolay, A | R | Scott, T | | Duffy, D | L |
| 5/30/2021 | | @ | LAA | W | 3-0 | | Keuchel, D | L | Keuchel, D | Scott, T | Pineda, M | R |
| 6/14/2021 | | | Ari | W | 10-3 | | Greinke, Z | R | Greinke, Z | Scott, T | Gallen, Z | R |
| 6/14/2021 | | @ | Mia | W | 3-2 | 11 | Greinke, Z | R | Gant, J | Rosenthal, T | Fleming, J | L |
| 6/15/2021 | | | Ari | W | 9-2 | | Keuchel, D | L | Keuchel, D | | Ryu, H | L |
| 6/15/2021 | | @ | Mia | W | 6-5 | | Keuchel, D | L | Rosenthal, T | Scott, T | Valdez, F | L |
| 6/16/2021 | | | Ari | L | 3-4 | | Happ, J | L | May, T | | Gray, S | R |
| 6/16/2021 | | @ | Mia | W | 7-6 | | King, M | R | King, M | Scott, T | Eflin, Z | R |
| 6/17/2021 | | | Col | L | 4-5 | | Montas, F | R | Gant, J | | Wainwright, A | R |
| 6/17/2021 | | @ | Phi | W | 5-1 | | Montas, F | R | Montas, F | Romano, J | Clevinger, M | R |
| 6/18/2021 | | | Col | W | 10-8 | 13 | Alzolay, A | R | Happ, J | | Godley, Z | R |
| 6/18/2021 | | @ | Phi | W | 5-2 | | Happ, J | L | Happ, J | Rosenthal, T | Hernandez, E | R |
| 6/19/2021 | | | Col | W | 4-0 | | Greinke, Z | R | Greinke, Z | | Cole, G | R |
| 6/19/2021 | | @ | Phi | W | 5-2 | | Greinke, Z | R | Greinke, Z | Romano, J | Castillo, L | R |
| 6/21/2021 | | @ | Atl | W | 8-4 | | King, M | R | King, M | | Bubic, K | L |
| 6/21/2021 | | | SF | W | 6-5 | | Keuchel, D | L | Bummer, A | | Peterson, D | L |
| 6/22/2021 | | @ | Atl | L | 1-2 | | Montas, F | R | Montas, F | | Castellani, R | R |
| 6/22/2021 | | | SF | W | 13-1 | | Happ, J | L | Happ, J | | Junis, J | R |
| 6/23/2021 | | @ | Atl | W | 3-2 | | Happ, J | L | Happ, J | Scott, T | Milone, T | L |
| 6/23/2021 | | | SF | L | 1-3 | | Alzolay, A | R | Bummer, A | | Hernandez, C | R |
| 6/24/2021 | | | SD | W | 12-1 | | Montas, F | R | Montas, F | | Giolito, L | R |
| 6/24/2021 | | @ | NYM | W | 12-9 | | Greinke, Z | R | Greinke, Z | Rosenthal, T | Pearson, N | R |
| 6/25/2021 | | | SD | W | 14-1 | | Greinke, Z | R | Greinke, Z | | Alcantara, S | R |
| 6/25/2021 | | @ | NYM | W | 6-3 | | King, M | R | King, M | Rosenthal, T | Mengden, D | R |
| 6/26/2021 | | | SD | W | 6-5 | 10 | Keuchel, D | L | Bummer, A | | Gausman, K | R |
| 6/26/2021 | | @ | NYM | L | 2-4 | | Keuchel, D | L | Keuchel, D | | Luzardo, J | L |
| 6/28/2021 | | | LAD | W | 2-0 | | Happ, J | L | Happ, J | Bummer, A | Porcello, R | R |
| 6/28/2021 | | @ | Was | L | 5-14 | | Happ, J | L | Happ, J | | Gonzales, M | L |
| 6/29/2021 | | | LAD | W | 8-4 | | Alzolay, A | R | Alzolay, A | | Snell, B | L |
| 6/29/2021 | | @ | Was | L | 6-7 | | Montas, F | R | May, T | | Buehler, W | R |
| 6/30/2021 | | | LAD | L | 3-5 | | Greinke, Z | R | Greinke, Z | | Lopez, P | R |
| 6/30/2021 | | @ | Was | W | 9-8 | | Greinke, Z | R | Gant, J | Rosenthal, T | Hendricks, K | R |
| 7/15/2021 | | | Cin | L | 8-12 | | Keuchel, D | L | Keuchel, D | | Woodruff, B | R |
| 7/15/2021 | | @ | Pit | W | 12-7 | | Montas, F | R | Montas, F | | Davies, Z | R |
| 7/16/2021 | | | Cin | L | 4-7 | | Alzolay, A | R | Alzolay, A | | Berrios, J | R |
| 7/16/2021 | | @ | Pit | W | 7-2 | | Keuchel, D | L | Keuchel, D | | McCullers, L | R |
| 7/17/2021 | | | Cin | L | 4-8 | | Greinke, Z | R | Greinke, Z | | Kikuchi, Y | L |
| 7/17/2021 | | @ | Pit | L | 3-5 | | King, M | R | King, M | | Senzatela, A | R |
| 7/19/2021 | | | StL | W | 6-2 | | Happ, J | L | Happ, J | | Newsome, L | R |
| 7/19/2021 | | @ | Mil | L | 3-4 | | Greinke, Z | R | Scott, T | | Gonsolin, T | R |
| 7/20/2021 | | | StL | W | 7-4 | | Keuchel, D | L | Keuchel, D | Bummer, A | Paxton, J | L |
| 7/20/2021 | | @ | Mil | L | 2-3 | | Montas, F | R | Montas, F | | Richards, G | R |
| 7/21/2021 | | | StL | W | 4-1 | | Alzolay, A | R | Alzolay, A | Rosenthal, T | Ray, R | L |
| 7/21/2021 | | @ | Mil | W | 10-3 | | Keuchel, D | L | Keuchel, D | | Kershaw, C | L |
| 7/22/2021 | | | Mil | L | 4-8 | | Greinke, Z | R | Greinke, Z | | Brault, S | L |
| 7/22/2021 | | @ | StL | L | 3-5 | | King, M | R | King, M | | Ray, R | L |
| 7/23/2021 | | | Mil | W | 9-3 | | Montas, F | R | Montas, F | | Richards, G | R |
| 7/23/2021 | | @ | StL | W | 4-3 | | Greinke, Z | R | Greinke, Z | Rosenthal, T | Paxton, J | L |
| 7/24/2021 | | | Mil | L | 0-4 | | Keuchel, D | L | Keuchel, D | | Kershaw, C | L |
| 7/24/2021 | | @ | StL | W | 3-1 | | Montas, F | R | Montas, F | Gant, J | Carrasco, C | R |
| 7/26/2021 | | | Pit | W | 7-1 | | Happ, J | L | Happ, J | Gant, J | Garcia, L | R |
| 7/26/2021 | | @ | Cin | W | 2-1 | | Keuchel, D | L | Keuchel, D | Gant, J | Lyles, J | R |
| 7/27/2021 | | | Pit | W | 12-6 | | Alzolay, A | R | Alzolay, A | | McCullers, L | R |
| 7/27/2021 | | @ | Cin | L | 6-7 | | King, M | R | King, M | | Berrios, J | R |
| 7/28/2021 | | | Pit | W | 7-4 | | Montas, F | R | Scott, T | Bummer, A | Mize, C | R |
| 7/28/2021 | | @ | Cin | L | 3-4 | | Greinke, Z | R | Treinen, B | | Plesac, Z | R |
| 8/13/2021 | | | Was | W | 10-7 | | Keuchel, D | L | Gant, J | Scott, T | Bassitt, C | R |
| 8/13/2021 | | @ | SD | L | 2-8 | | Montas, F | R | Montas, F | | Giolito, L | R |
| 8/14/2021 | | | Was | W | 7-2 | | Alzolay, A | R | Alzolay, A | | Gonzales, M | L |
| 8/14/2021 | | @ | SD | W | 6-4 | | Greinke, Z | R | Greinke, Z | Romano, J | Fiers, M | R |
| 8/15/2021 | | | Was | L | 4-8 | | Greinke, Z | R | Greinke, Z | | Hendricks, K | R |
| 8/15/2021 | | @ | SD | W | 4-3 | | Happ, J | L | Kelly, J | Rosenthal, T | Perez, M | L |
| 8/16/2021 | | | Atl | L | 2-3 | | Happ, J | L | Happ, J | | Corbin, P | L |
| 8/16/2021 | | @ | Ari | W | 16-8 | | King, M | R | Scott, T | | Wojciechowski, A | R |
| 8/17/2021 | | | Atl | W | 10-5 | | Montas, F | R | Romano, J | | Castellani, R | R |
| 8/17/2021 | | @ | Ari | W | 8-2 | | Keuchel, D | L | Keuchel, D | | Gallen, Z | R |
| 8/18/2021 | | | Atl | W | 6-3 | | Keuchel, D | L | Keuchel, D | Scott, T | Bubic, K | L |
| 8/18/2021 | | @ | Ari | L | 1-12 | | Montas, F | R | Montas, F | | Ryu, H | L |
| 8/20/2021 | | | Phi | W | 7-0 | | Alzolay, A | R | Alzolay, A | | Castillo, L | R |
| 8/20/2021 | | @ | Col | W | 10-6 | | Greinke, Z | R | Greinke, Z | | Means, J | L |
| 8/21/2021 | | | Phi | W | 4-3 | 11 | Greinke, Z | R | Romano, J | | Sheffield, J | L |
| 8/21/2021 | | @ | Col | L | 3-4 | 11 | Happ, J | L | Scott, T | | Wainwright, A | R |
| 8/22/2021 | | | Phi | W | 17-3 | | Montas, F | R | Montas, F | | Schmidt, C | R |
| 8/22/2021 | | @ | Col | L | 2-12 | | King, M | R | King, M | | Bieber, S | R |
| 8/23/2021 | | | NYM | W | 15-3 | | Happ, J | L | Happ, J | | Erlin, R | L |
| 8/23/2021 | | @ | LAD | L | 1-6 | | Montas, F | R | Montas, F | | deGrom, J | R |
| 8/24/2021 | | | NYM | L | 5-7 | | Keuchel, D | L | Bummer, A | | Gonzalez, G | L |
| 8/24/2021 | | @ | LAD | W | 9-4 | | Keuchel, D | L | Keuchel, D | | Porcello, R | R |
| 8/25/2021 | | | NYM | L | 0-2 | | Alzolay, A | R | Alzolay, A | | Mengden, D | R |
| 8/25/2021 | | @ | LAD | W | 9-2 | | Greinke, Z | R | Greinke, Z | | Lopez, P | R |
| 8/27/2021 | | | Mia | W | 4-3 | | Greinke, Z | R | Scott, T | Romano, J | Eflin, Z | R |
| 8/27/2021 | | @ | SF | W | 3-0 | | Happ, J | L | Happ, J | Scott, T | Anderson, I | R |
| 8/28/2021 | | | Mia | L | 8-12 | | Montas, F | R | Montas, F | | Tomlin, J | R |
| 8/28/2021 | | @ | SF | L | 6-8 | | King, M | R | Romano, J | | Junis, J | R |
| 8/29/2021 | | | Mia | L | 2-4 | | Keuchel, D | L | Keuchel, D | | Brubaker, J | R |
| 8/29/2021 | | @ | SF | L | 0-2 | | Montas, F | R | Montas, F | | Wheeler, Z | R |
| 9/13/2021 | | | StL | W | 2-0 | | Keuchel, D | L | Keuchel, D | Gant, J | Ray, R | L |
| 9/13/2021 | | @ | Mil | L | 5-9 | | Montas, F | R | Montas, F | | Richards, G | R |
| 9/14/2021 | | | StL | L | 4-10 | | Greinke, Z | R | Greinke, Z | | Heaney, A | L |
| 9/14/2021 | | @ | Mil | L | 2-18 | | Kelly, J | R | Kelly, J | | Gonsolin, T | R |
| 9/15/2021 | | | StL | W | 9-1 | | Happ, J | L | Happ, J | | Newsome, L | R |
| 9/15/2021 | | @ | Mil | W | 7-4 | | Keuchel, D | L | Keuchel, D | Treinen, B | Morton, C | R |
| 9/17/2021 | | | Pit | W | 6-5 | | Kelly, J | R | Gant, J | | Montgomery, J | L |
| 9/17/2021 | | @ | Cin | W | 6-3 | | King, M | R | King, M | Rosenthal, T | Plesac, Z | R |
| 9/18/2021 | | | Pit | W | 9-0 | | Keuchel, D | L | Keuchel, D | | Davies, Z | R |
| 9/18/2021 | | @ | Cin | L | 3-4 | 10 | Montas, F | R | Gant, J | | Woodruff, B | R |
| 9/19/2021 | | | Pit | W | 5-3 | | Greinke, Z | R | Greinke, Z | Scott, T | Senzatela, A | R |
| 9/19/2021 | | @ | Cin | W | 4-3 | | Greinke, Z | R | Greinke, Z | Rosenthal, T | Berrios, J | R |
| 9/20/2021 | | | Cin | W | 5-1 | | Happ, J | L | Happ, J | | Woodruff, B | R |
| 9/20/2021 | | @ | Pit | W | 6-2 | | Kelly, J | R | Treinen, B | | Montgomery, J | L |
| 9/21/2021 | | | Cin | L | 4-5 | | Montas, F | R | Montas, F | | Lyles, J | R |
| 9/21/2021 | | @ | Pit | W | 3-2 | | King, M | R | King, M | Rosenthal, T | Mize, C | R |
| 9/22/2021 | | | Cin | L | 4-8 | | Keuchel, D | L | Keuchel, D | | Strasburg, S | R |
| 9/22/2021 | | @ | Pit | W | 5-4 | | Montas, F | R | Montas, F | Scott, T | Davies, Z | R |
| 9/24/2021 | | | Mil | W | 4-0 | | Kelly, J | R | Reed, C | | Gonsolin, T | R |
| 9/24/2021 | | @ | StL | L | 8-9 | | King, M | R | King, M | | Harvey, M | R |
| 9/25/2021 | | | Mil | L | 3-4 | 10 | Greinke, Z | R | Scott, T | | Brault, S | L |
| 9/25/2021 | | @ | StL | L | 6-7 | | Kelly, J | R | Romano, J | | Heaney, A | L |
| 9/26/2021 | | | Mil | L | 6-7 | 11 | Montas, F | R | May, T | | Morton, C | R |
| 9/26/2021 | | @ | StL | W | 5-4 | | Montas, F | R | Montas, F | Gant, J | Paxton, J | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/15/2021 | | | Mil | L | | 2 | 4 | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/15/2021 | | @ | StL | W | Ruiz, R | 6 | 5 | 1 | 1 | .500 | 1-1 | W1 | 2 |
| 4/16/2021 | | | Mil | L | | 2 | 5 | 1 | 2 | .333 | 1-2 | L1 | 3 |
| 4/16/2021 | | @ | StL | W | Cespedes, Y | 2 | 1 | 2 | 2 | .500 | 2-2 | W1 | 4 |
| 4/17/2021 | | | Mil | W | Ramos, W | 8 | 6 | 3 | 2 | .600 | 3-2 | W2 | 5 |
| 4/17/2021 | | @ | StL | W | Moreland, M | 7 | 6 | 4 | 2 | .667 | 4-2 | W3 | 6 |
| 4/19/2021 | | | Cin | L | | 9 | 10 | 4 | 3 | .571 | 4-3 | L1 | 7 |
| 4/19/2021 | | @ | Pit | W | Heyward, J | 13 | 4 | 5 | 3 | .625 | 5-3 | W1 | 8 |
| 4/20/2021 | | | Cin | W | Moreland, M | 3 | 0 | 6 | 3 | .667 | 6-3 | W2 | 9 |
| 4/20/2021 | | @ | Pit | L | | 3 | 5 | 6 | 4 | .600 | 6-4 | L1 | 10 |
| 4/21/2021 | | | Cin | L | | 4 | 5 | 6 | 5 | .545 | 6-4 | L2 | 11 |
| 4/21/2021 | | @ | Pit | W | Moreland, M | 4 | 3 | 7 | 5 | .583 | 6-4 | W1 | 12 |
| 4/22/2021 | | | Pit | L | | 1 | 3 | 7 | 6 | .538 | 6-4 | L1 | 13 |
| 4/22/2021 | | @ | Cin | W | Garcia, A | 9 | 4 | 8 | 6 | .571 | 6-4 | W1 | 14 |
| 4/23/2021 | | | Pit | W | Dalbec, B | 4 | 3 | 9 | 6 | .600 | 6-4 | W2 | 15 |
| 4/23/2021 | | @ | Cin | W | Moreland, M | 8 | 7 | 10 | 6 | .625 | 6-4 | W3 | 16 |
| 4/24/2021 | | | Pit | W | Myers, W | 9 | 3 | 11 | 6 | .647 | 7-3 | W4 | 17 |
| 4/24/2021 | | @ | Cin | L | | 4 | 5 | 11 | 7 | .611 | 6-4 | L1 | 18 |
| 4/26/2021 | | | StL | W | Maybin, C | 7 | 6 | 12 | 7 | .632 | 6-4 | W1 | 19 |
| 4/26/2021 | | @ | Mil | L | | 0 | 1 | 12 | 8 | .600 | 6-4 | L1 | 20 |
| 4/27/2021 | | | StL | W | Ruiz, R | 6 | 5 | 13 | 8 | .619 | 7-3 | W1 | 21 |
| 4/27/2021 | | @ | Mil | W | Garcia, A | 3 | 1 | 14 | 8 | .636 | 7-3 | W2 | 22 |
| 4/28/2021 | | | StL | W | Moreland, M | 2 | 1 | 15 | 8 | .652 | 8-2 | W3 | 23 |
| 4/28/2021 | | @ | Mil | L | | 1 | 8 | 15 | 9 | .625 | 7-3 | L1 | 24 |
| 5/13/2021 | | | TB | W | Heyward, J | 10 | 2 | 16 | 9 | .640 | 7-3 | W1 | 25 |
| 5/13/2021 | | @ | Tex | W | Myers, W | 4 | 1 | 17 | 9 | .654 | 7-3 | W2 | 26 |
| 5/14/2021 | | | TB | W | | 5 | 4 | 18 | 9 | .667 | 7-3 | W3 | 27 |
| 5/14/2021 | | @ | Tex | L | | 7 | 8 | 18 | 10 | .643 | 7-3 | L1 | 28 |
| 5/15/2021 | | | TB | W | Dalbec, B | 14 | 3 | 19 | 10 | .655 | 7-3 | W1 | 29 |
| 5/15/2021 | | @ | Tex | W | Choo, S | 16 | 2 | 20 | 10 | .667 | 8-2 | W2 | 30 |
| 5/17/2021 | | | Tor | W | Moreland, M | 9 | 5 | 21 | 10 | .677 | 8-2 | W3 | 31 |
| 5/17/2021 | | @ | Sea | L | | 1 | 3 | 21 | 11 | .656 | 7-3 | L1 | 32 |
| 5/18/2021 | | | Tor | L | | 3 | 7 | 21 | 12 | .636 | 6-4 | L2 | 33 |
| 5/18/2021 | | @ | Sea | W | Garcia, L | 7 | 2 | 22 | 12 | .647 | 7-3 | W1 | 34 |
| 5/19/2021 | | | Tor | W | Ramos, W | 5 | 3 | 23 | 12 | .657 | 7-3 | W2 | 35 |
| 5/19/2021 | | @ | Sea | L | | 7 | 20 | 23 | 13 | .639 | 6-4 | L1 | 36 |
| 5/21/2021 | | | Bal | L | | 8 | 12 | 23 | 14 | .622 | 5-5 | L2 | 37 |
| 5/21/2021 | | @ | Hou | L | | 3 | 8 | 23 | 15 | .605 | 5-5 | L3 | 38 |
| 5/22/2021 | | | Bal | L | | 0 | 1 | 23 | 16 | .590 | 4-6 | L4 | 39 |
| 5/22/2021 | | @ | Hou | W | Gregorius, D | 11 | 1 | 24 | 16 | .600 | 4-6 | W1 | 40 |
| 5/23/2021 | | | Bal | W | Myers, W | 5 | 2 | 25 | 16 | .610 | 4-6 | W2 | 41 |
| 5/23/2021 | | @ | Hou | W | Garcia, L | 8 | 0 | 26 | 16 | .619 | 5-5 | W3 | 42 |
| 5/24/2021 | | | Bos | L | | 5 | 6 | 26 | 17 | .605 | 5-5 | L1 | 43 |
| 5/24/2021 | | @ | Oak | L | | 3 | 7 | 26 | 18 | .591 | 4-6 | L2 | 44 |
| 5/25/2021 | | | Bos | W | Dalbec, B | 4 | 2 | 27 | 18 | .600 | 4-6 | W1 | 45 |
| 5/25/2021 | | @ | Oak | L | | 4 | 7 | 27 | 19 | .587 | 4-6 | L1 | 46 |
| 5/26/2021 | | | Bos | L | | 6 | 9 | 27 | 20 | .574 | 4-6 | L2 | 47 |
| 5/26/2021 | | @ | Oak | W | Moreland, M | 2 | 1 | 28 | 20 | .583 | 5-5 | W1 | 48 |
| 5/28/2021 | | | NYY | W | Ramos, W | 5 | 3 | 29 | 20 | .592 | 6-4 | W2 | 49 |
| 5/28/2021 | | @ | LAA | W | Gregorius, D | 4 | 3 | 30 | 20 | .600 | 6-4 | W3 | 50 |
| 5/29/2021 | | | NYY | W | Ramos, W | 6 | 5 | 31 | 20 | .608 | 6-4 | W4 | 51 |
| 5/29/2021 | | @ | LAA | L | | 2 | 7 | 31 | 21 | .596 | 5-5 | L1 | 52 |
| 5/30/2021 | | | NYY | L | | 2 | 3 | 31 | 22 | .585 | 5-5 | L2 | 53 |
| 5/30/2021 | | @ | LAA | W | Moreland, M | 3 | 0 | 32 | 22 | .593 | 6-4 | W1 | 54 |
| 6/14/2021 | | | Ari | W | Gregorius, D | 10 | 3 | 33 | 22 | .600 | 6-4 | W2 | 55 |
| 6/14/2021 | | @ | Mia | W | Gregorius, D | 3 | 2 | 34 | 22 | .607 | 7-3 | W3 | 56 |
| 6/15/2021 | | | Ari | W | Dalbec, B | 9 | 2 | 35 | 22 | .614 | 8-2 | W4 | 57 |
| 6/15/2021 | | @ | Mia | W | Garcia, A | 6 | 5 | 36 | 22 | .621 | 8-2 | W5 | 58 |
| 6/16/2021 | | | Ari | L | | 3 | 4 | 36 | 23 | .610 | 7-3 | L1 | 59 |
| 6/16/2021 | | @ | Mia | W | Wendle, J | 7 | 6 | 37 | 23 | .617 | 7-3 | W1 | 60 |
| 6/17/2021 | | | Col | L | | 4 | 5 | 37 | 24 | .607 | 6-4 | L1 | 61 |
| 6/17/2021 | | @ | Phi | W | Choo, S | 5 | 1 | 38 | 24 | .613 | 7-3 | W1 | 62 |
| 6/18/2021 | | | Col | W | Ramos, W | 10 | 8 | 39 | 24 | .619 | 8-2 | W2 | 63 |
| 6/18/2021 | | @ | Phi | W | Choo, S | 5 | 2 | 40 | 24 | .625 | 8-2 | W3 | 64 |
| 6/19/2021 | | | Col | W | Fuentes, J | 4 | 0 | 41 | 24 | .631 | 8-2 | W4 | 65 |
| 6/19/2021 | | @ | Phi | W | Heyward, J | 5 | 2 | 42 | 24 | .636 | 8-2 | W5 | 66 |
| 6/21/2021 | | @ | Atl | W | Perez, M | 8 | 4 | 43 | 24 | .642 | 8-2 | W6 | 67 |
| 6/21/2021 | | | SF | W | Fuentes, J | 6 | 5 | 44 | 24 | .647 | 8-2 | W7 | 68 |
| 6/22/2021 | | @ | Atl | L | | 1 | 2 | 44 | 25 | .638 | 8-2 | L1 | 69 |
| 6/22/2021 | | | SF | W | Dalbec, B | 13 | 1 | 45 | 25 | .643 | 8-2 | W1 | 70 |
| 6/23/2021 | | @ | Atl | W | Bishop, B | 3 | 2 | 46 | 25 | .648 | 9-1 | W2 | 71 |
| 6/23/2021 | | | SF | L | | 1 | 3 | 46 | 26 | .639 | 8-2 | L1 | 72 |
| 6/24/2021 | | | SD | W | Gregorius, D | 12 | 1 | 47 | 26 | .644 | 8-2 | W1 | 73 |
| 6/24/2021 | | @ | NYM | W | Perez, M | 12 | 9 | 48 | 26 | .649 | 8-2 | W2 | 74 |
| 6/25/2021 | | | SD | W | Ramos, W | 14 | 1 | 49 | 26 | .653 | 8-2 | W3 | 75 |
| 6/25/2021 | | @ | NYM | W | Ramos, W | 6 | 3 | 50 | 26 | .658 | 8-2 | W4 | 76 |
| 6/26/2021 | | | SD | W | Ramos, W | 6 | 5 | 51 | 26 | .662 | 8-2 | W5 | 77 |
| 6/26/2021 | | @ | NYM | L | | 2 | 4 | 51 | 27 | .654 | 7-3 | L1 | 78 |
| 6/28/2021 | | | LAD | W | Moreland, M | 2 | 0 | 52 | 27 | .658 | 8-2 | W1 | 79 |
| 6/28/2021 | | @ | Was | L | | 5 | 14 | 52 | 28 | .650 | 7-3 | L1 | 80 |
| 6/29/2021 | | | LAD | W | Dalbec, B | 8 | 4 | 53 | 28 | .654 | 7-3 | W1 | 81 |
| 6/29/2021 | | @ | Was | L | | 6 | 7 | 53 | 29 | .646 | 7-3 | L1 | 82 |
| 6/30/2021 | | | LAD | L | | 3 | 5 | 53 | 30 | .639 | 6-4 | L2 | 83 |
| 6/30/2021 | | @ | Was | W | Myers, W | 9 | 8 | 54 | 30 | .643 | 6-4 | W1 | 84 |
| 7/15/2021 | | | Cin | L | | 8 | 12 | 54 | 31 | .635 | 5-5 | L1 | 85 |
| 7/15/2021 | | @ | Pit | W | Choo, S | 12 | 7 | 55 | 31 | .640 | 5-5 | W1 | 86 |
| 7/16/2021 | | | Cin | L | | 4 | 7 | 55 | 32 | .632 | 4-6 | L1 | 87 |
| 7/16/2021 | | @ | Pit | W | Diaz, A | 7 | 2 | 56 | 32 | .636 | 5-5 | W1 | 88 |
| 7/17/2021 | | | Cin | L | | 4 | 8 | 56 | 33 | .629 | 4-6 | L1 | 89 |
| 7/17/2021 | | @ | Pit | L | | 3 | 5 | 56 | 34 | .622 | 4-6 | L2 | 90 |
| 7/19/2021 | | | StL | W | Dalbec, B | 6 | 2 | 57 | 34 | .626 | 4-6 | W1 | 91 |
| 7/19/2021 | | @ | Mil | L | | 3 | 4 | 57 | 35 | .620 | 4-6 | L1 | 92 |
| 7/20/2021 | | | StL | W | Maybin, C | 7 | 4 | 58 | 35 | .624 | 5-5 | W1 | 93 |
| 7/20/2021 | | @ | Mil | L | | 2 | 3 | 58 | 36 | .617 | 4-6 | L1 | 94 |
| 7/21/2021 | | | StL | W | Gregorius, D | 4 | 1 | 59 | 36 | .621 | 5-5 | W1 | 95 |
| 7/21/2021 | | @ | Mil | W | Moreland, M | 10 | 3 | 60 | 36 | .625 | 5-5 | W2 | 96 |
| 7/22/2021 | | | Mil | L | | 4 | 8 | 60 | 37 | .619 | 5-5 | L1 | 97 |
| 7/22/2021 | | @ | StL | L | | 3 | 5 | 60 | 38 | .612 | 4-6 | L2 | 98 |
| 7/23/2021 | | | Mil | W | Myers, W | 9 | 3 | 61 | 38 | .616 | 5-5 | W1 | 99 |
| 7/23/2021 | | @ | StL | W | Ruiz, R | 4 | 3 | 62 | 38 | .620 | 6-4 | W2 | 100 |
| 7/24/2021 | | | Mil | L | | 0 | 4 | 62 | 39 | .614 | 5-5 | L1 | 101 |
| 7/24/2021 | | @ | StL | W | | 3 | 1 | 63 | 39 | .618 | 6-4 | W1 | 102 |
| 7/26/2021 | | | Pit | W | Wendle, J | 7 | 1 | 64 | 39 | .621 | 6-4 | W2 | 103 |
| 7/26/2021 | | @ | Cin | W | Heyward, J | 2 | 1 | 65 | 39 | .625 | 7-3 | W3 | 104 |
| 7/27/2021 | | | Pit | W | Dalbec, B | 12 | 6 | 66 | 39 | .629 | 7-3 | W4 | 105 |
| 7/27/2021 | | @ | Cin | L | | 6 | 7 | 66 | 40 | .623 | 6-4 | L1 | 106 |
| 7/28/2021 | | | Pit | W | Wendle, J | 7 | 4 | 67 | 40 | .626 | 7-3 | W1 | 107 |
| 7/28/2021 | | @ | Cin | L | | 3 | 4 | 67 | 41 | .620 | 7-3 | L1 | 108 |
| 8/13/2021 | | | Was | W | Fuentes, J | 10 | 7 | 68 | 41 | .624 | 7-3 | W1 | 109 |
| 8/13/2021 | | @ | SD | L | | 2 | 8 | 68 | 42 | .618 | 6-4 | L1 | 110 |
| 8/14/2021 | | | Was | W | Fuentes, J | 7 | 2 | 69 | 42 | .622 | 7-3 | W1 | 111 |
| 8/14/2021 | | @ | SD | W | Myers, W | 6 | 4 | 70 | 42 | .625 | 7-3 | W2 | 112 |
| 8/15/2021 | | | Was | L | | 4 | 8 | 70 | 43 | .619 | 6-4 | L1 | 113 |
| 8/15/2021 | | @ | SD | W | | 4 | 3 | 71 | 43 | .623 | 6-4 | W1 | 114 |
| 8/16/2021 | | | Atl | L | | 2 | 3 | 71 | 44 | .617 | 5-5 | L1 | 115 |
| 8/16/2021 | | @ | Ari | W | Ruiz, R | 16 | 8 | 72 | 44 | .621 | 6-4 | W1 | 116 |
| 8/17/2021 | | | Atl | W | Fuentes, J | 10 | 5 | 73 | 44 | .624 | 6-4 | W2 | 117 |
| 8/17/2021 | | @ | Ari | W | Myers, W | 8 | 2 | 74 | 44 | .627 | 7-3 | W3 | 118 |
| 8/18/2021 | | | Atl | W | Ramos, W | 6 | 3 | 75 | 44 | .630 | 7-3 | W4 | 119 |
| 8/18/2021 | | @ | Ari | L | | 1 | 12 | 75 | 45 | .625 | 7-3 | L1 | 120 |
| 8/20/2021 | | | Phi | W | Myers, W | 7 | 0 | 76 | 45 | .628 | 7-3 | W1 | 121 |
| 8/20/2021 | | @ | Col | W | Myers, W | 10 | 6 | 77 | 45 | .631 | 7-3 | W2 | 122 |
| 8/21/2021 | | | Phi | W | Moreland, M | 4 | 3 | 78 | 45 | .634 | 8-2 | W3 | 123 |
| 8/21/2021 | | @ | Col | L | | 3 | 4 | 78 | 46 | .629 | 7-3 | L1 | 124 |
| 8/22/2021 | | | Phi | W | Fuentes, J | 17 | 3 | 79 | 46 | .632 | 8-2 | W1 | 125 |
| 8/22/2021 | | @ | Col | L | | 2 | 12 | 79 | 47 | .627 | 7-3 | L1 | 126 |
| 8/23/2021 | | | NYM | W | Maybin, C | 15 | 3 | 80 | 47 | .630 | 7-3 | W1 | 127 |
| 8/23/2021 | | @ | LAD | L | | 1 | 6 | 80 | 48 | .625 | 6-4 | L1 | 128 |
| 8/24/2021 | | | NYM | L | | 5 | 7 | 80 | 49 | .620 | 5-5 | L2 | 129 |
| 8/24/2021 | | @ | LAD | W | Maybin, C | 9 | 4 | 81 | 49 | .623 | 6-4 | W1 | 130 |
| 8/25/2021 | | | NYM | L | | 0 | 2 | 81 | 50 | .618 | 5-5 | L1 | 131 |
| 8/25/2021 | | @ | LAD | W | Wendle, J | 9 | 2 | 82 | 50 | .621 | 5-5 | W1 | 132 |
| 8/27/2021 | | | Mia | W | Gregorius, D | 4 | 3 | 83 | 50 | .624 | 5-5 | W2 | 133 |
| 8/27/2021 | | @ | SF | W | Wendle, J | 3 | 0 | 84 | 50 | .627 | 6-4 | W3 | 134 |
| 8/28/2021 | | | Mia | L | | 8 | 12 | 84 | 51 | .622 | 5-5 | L1 | 135 |
| 8/28/2021 | | @ | SF | L | | 6 | 8 | 84 | 52 | .618 | 5-5 | L2 | 136 |
| 8/29/2021 | | | Mia | L | | 2 | 4 | 84 | 53 | .613 | 4-6 | L3 | 137 |
| 8/29/2021 | | @ | SF | L | | 0 | 2 | 84 | 54 | .609 | 4-6 | L4 | 138 |
| 9/13/2021 | | | StL | W | Fuentes, J | 2 | 0 | 85 | 54 | .612 | 5-5 | W1 | 139 |
| 9/13/2021 | | @ | Mil | L | | 5 | 9 | 85 | 55 | .607 | 4-6 | L1 | 140 |
| 9/14/2021 | | | StL | L | | 4 | 10 | 85 | 56 | .603 | 4-6 | L2 | 141 |
| 9/14/2021 | | @ | Mil | L | | 2 | 18 | 85 | 57 | .599 | 3-7 | L3 | 142 |
| 9/15/2021 | | | StL | W | Myers, W | 9 | 1 | 86 | 57 | .601 | 3-7 | W1 | 143 |
| 9/15/2021 | | @ | Mil | W | Gregorius, D | 7 | 4 | 87 | 57 | .604 | 3-7 | W2 | 144 |
| 9/17/2021 | | | Pit | W | Ramos, W | 6 | 5 | 88 | 57 | .607 | 4-6 | W3 | 145 |
| 9/17/2021 | | @ | Cin | W | Moreland, M | 6 | 3 | 89 | 57 | .610 | 5-5 | W4 | 146 |
| 9/18/2021 | | | Pit | W | Wendle, J | 9 | 0 | 90 | 57 | .612 | 6-4 | W5 | 147 |
| 9/18/2021 | | @ | Cin | L | | 3 | 4 | 90 | 58 | .608 | 6-4 | L1 | 148 |
| 9/19/2021 | | | Pit | W | Heyward, J | 5 | 3 | 91 | 58 | .611 | 6-4 | W1 | 149 |
| 9/19/2021 | | @ | Cin | W | Wendle, J | 4 | 3 | 92 | 58 | .613 | 7-3 | W2 | 150 |
| 9/20/2021 | | | Cin | W | Moreland, M | 5 | 1 | 93 | 58 | .616 | 8-2 | W3 | 151 |
| 9/20/2021 | | @ | Pit | W | Myers, W | 6 | 2 | 94 | 58 | .618 | 9-1 | W4 | 152 |
| 9/21/2021 | | | Cin | L | | 4 | 5 | 94 | 59 | .614 | 8-2 | L1 | 153 |
| 9/21/2021 | | @ | Pit | W | Wendle, J | 3 | 2 | 95 | 59 | .617 | 8-2 | W1 | 154 |
| 9/22/2021 | | | Cin | L | | 4 | 8 | 95 | 60 | .613 | 7-3 | L1 | 155 |
| 9/22/2021 | | @ | Pit | W | | 5 | 4 | 96 | 60 | .615 | 7-3 | W1 | 156 |
| 9/24/2021 | | | Mil | W | Myers, W | 4 | 0 | 97 | 60 | .618 | 7-3 | W2 | 157 |
| 9/24/2021 | | @ | StL | L | | 8 | 9 | 97 | 61 | .614 | 7-3 | L1 | 158 |
| 9/25/2021 | | | Mil | L | | 3 | 4 | 97 | 62 | .610 | 6-4 | L2 | 159 |
| 9/25/2021 | | @ | StL | L | | 6 | 7 | 97 | 63 | .606 | 5-5 | L3 | 160 |
| 9/26/2021 | | | Mil | L | | 6 | 7 | 97 | 64 | .602 | 4-6 | L4 | 161 |
| 9/26/2021 | | @ | StL | W | Ramos, W | 5 | 4 | 98 | 64 | .605 | 4-6 | W1 | 162 |