Team game results - 2021 Minnesota Twins
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/15/2021 | | @ | Cle | W | 6-1 | | Urena, J | R | Urena, J | | Civale, A | R |
| 4/15/2021 | | | ChW | W | 11-5 | | Nola, A | R | Farmer, B | | Freeland, K | L |
| 4/16/2021 | | @ | Cle | L | 0-3 | | Nola, A | R | Nola, A | | Keller, B | R |
| 4/16/2021 | | | ChW | L | 4-7 | | Allard, K | L | Smith, W | | Tanaka, M | R |
| 4/17/2021 | | @ | Cle | W | 7-4 | | Musgrove, J | R | Musgrove, J | Colome, A | Sanchez, S | R |
| 4/17/2021 | | | ChW | W | 6-3 | | Musgrove, J | R | Musgrove, J | Colome, A | Odorizzi, J | R |
| 4/19/2021 | | @ | Det | W | 4-2 | | Akin, K | L | Kennedy, I | Colome, A | Flaherty, J | R |
| 4/19/2021 | | | KC | W | 7-2 | | Akin, K | L | Farmer, B | | Arrieta, J | R |
| 4/20/2021 | | @ | Det | L | 2-16 | | Kremer, D | R | Kremer, D | | Lester, J | L |
| 4/20/2021 | | | KC | W | 2-0 | | Nola, A | R | Nola, A | Colome, A | Lamet, D | R |
| 4/21/2021 | | @ | Det | W | 5-4 | | Urena, J | R | Urena, J | Colome, A | Marquez, G | R |
| 4/21/2021 | | | KC | L | 2-4 | | Allard, K | L | Farmer, B | | Rogers, T | L |
| 4/22/2021 | | @ | KC | W | 3-1 | | Nola, A | R | Nola, A | Farmer, B | Singer, B | R |
| 4/22/2021 | | | Det | W | 3-1 | | Musgrove, J | R | Musgrove, J | Colome, A | Cody, K | R |
| 4/23/2021 | | @ | KC | L | 2-6 | | Musgrove, J | R | Musgrove, J | | Lindblom, J | R |
| 4/23/2021 | | | Det | L | 4-5 | 11 | Mahle, T | R | Floro, D | | Fairbanks, P | R |
| 4/24/2021 | | @ | KC | W | 2-1 | | Akin, K | L | Akin, K | Colome, A | Lamet, D | R |
| 4/24/2021 | | | Det | W | 3-0 | | Nola, A | R | Nola, A | Farmer, B | Lester, J | L |
| 4/26/2021 | | @ | ChW | W | 1-0 | | Kremer, D | R | Kremer, D | Colome, A | Antone, T | R |
| 4/26/2021 | | | Cle | L | 3-7 | | Akin, K | L | Akin, K | | Weber, R | R |
| 4/27/2021 | | @ | ChW | L | 2-7 | | Urena, J | R | Urena, J | | Freeland, K | L |
| 4/27/2021 | | | Cle | W | 5-4 | | Allard, K | L | Allard, K | Colome, A | Keller, B | R |
| 4/28/2021 | | @ | ChW | L | 0-4 | | Nola, A | R | Nola, A | | Eovaldi, N | R |
| 4/28/2021 | | | Cle | W | 6-2 | | Mahle, T | R | Mahle, T | | Castano, D | L |
| 5/13/2021 | | @ | SD | W | 6-1 | | Nola, A | R | Nola, A | | Perez, M | L |
| 5/13/2021 | | | Phi | W | 6-3 | | Nola, A | R | Colome, A | | Castillo, L | R |
| 5/14/2021 | | @ | SD | W | 3-2 | | Mahle, T | R | Mahle, T | Colome, A | Giolito, L | R |
| 5/14/2021 | | | Phi | W | 2-1 | | Allard, K | L | Allard, K | Colome, A | Sheffield, J | L |
| 5/15/2021 | | @ | SD | L | 6-8 | | Allard, K | L | Allard, K | | Fiers, M | R |
| 5/15/2021 | | | Phi | W | 8-3 | | Musgrove, J | R | Musgrove, J | | Clevinger, M | R |
| 5/17/2021 | | | NYM | W | 12-2 | | Akin, K | L | Akin, K | | Erlin, R | L |
| 5/17/2021 | | @ | Ari | L | 5-6 | | Kremer, D | R | Floro, D | | Wojciechowski, A | R |
| 5/18/2021 | | | NYM | L | 2-5 | | Musgrove, J | R | Musgrove, J | | Gonzalez, G | L |
| 5/18/2021 | | @ | Ari | L | 0-7 | | Urena, J | R | Urena, J | | Ryu, H | L |
| 5/19/2021 | | | NYM | L | 0-2 | | Mahle, T | R | Mahle, T | | Dunning, D | R |
| 5/19/2021 | | @ | Ari | L | 0-1 | | Nola, A | R | Nola, A | | Gallen, Z | R |
| 5/21/2021 | | | Mia | W | 2-0 | | Nola, A | R | Nola, A | Colome, A | Valdez, F | L |
| 5/21/2021 | | @ | Col | L | 6-11 | | Mahle, T | R | Mahle, T | | Bieber, S | R |
| 5/22/2021 | | | Mia | L | 4-6 | | Allard, K | L | Floro, D | | Eflin, Z | R |
| 5/22/2021 | | @ | Col | L | 3-4 | 14 | Allard, K | L | Smith, W | | Cole, G | R |
| 5/23/2021 | | | Mia | W | 8-4 | | Musgrove, J | R | Musgrove, J | | Tomlin, J | R |
| 5/23/2021 | | @ | Col | L | 2-5 | | Kremer, D | R | Kremer, D | | Wainwright, A | R |
| 5/24/2021 | | @ | LAD | W | 8-7 | | Urena, J | R | Smith, W | | Houser, A | R |
| 5/24/2021 | | | Was | W | 4-1 | | Akin, K | L | Akin, K | Colome, A | Gsellman, R | R |
| 5/25/2021 | | @ | LAD | L | 1-5 | | Nola, A | R | Nola, A | | Lopez, P | R |
| 5/25/2021 | | | Was | L | 0-4 | | Mahle, T | R | Mahle, T | | Buehler, W | R |
| 5/26/2021 | | @ | LAD | L | 3-12 | | Mahle, T | R | Mahle, T | | Snell, B | L |
| 5/26/2021 | | | Was | W | 2-0 | | Nola, A | R | Nola, A | | Gonzales, M | L |
| 5/28/2021 | | @ | SF | W | 5-1 | | Allard, K | L | Leibrandt, B | | Peterson, D | L |
| 5/28/2021 | | | Atl | L | 4-5 | | Allard, K | L | Allard, K | | Barria, J | R |
| 5/29/2021 | | @ | SF | W | 8-4 | | Kremer, D | R | Leibrandt, B | | Anderson, I | R |
| 5/29/2021 | | | Atl | W | 1-0 | | Musgrove, J | R | Floro, D | Colome, A | Bubic, K | L |
| 5/30/2021 | | @ | SF | L | 6-7 | | Urena, J | R | Urena, J | | Junis, J | R |
| 5/30/2021 | | | Atl | W | 10-9 | | Mahle, T | R | Floro, D | | Corbin, P | L |
| 6/14/2021 | | @ | Bal | L | 4-8 | | Allard, K | L | Allard, K | | Turnbull, S | R |
| 6/14/2021 | | | Tex | L | 0-5 | | Nola, A | R | Nola, A | | Sanchez, A | R |
| 6/15/2021 | | @ | Bal | W | 7-3 | | Nola, A | R | Nola, A | Colome, A | Mills, A | R |
| 6/15/2021 | | | Tex | W | 4-3 | | Allard, K | L | Allard, K | Colome, A | Thorpe, L | L |
| 6/16/2021 | | @ | Bal | L | 6-8 | | Mahle, T | R | Mahle, T | | Cobb, A | R |
| 6/16/2021 | | | Tex | W | 10-1 | | Musgrove, J | R | Musgrove, J | | Stripling, R | R |
| 6/17/2021 | | | Hou | W | 2-0 | | Akin, K | L | Akin, K | Colome, A | Hill, R | L |
| 6/17/2021 | | @ | TB | W | 13-0 | | Urena, J | R | Urena, J | | Lopez, R | R |
| 6/18/2021 | | | Hou | W | 2-1 | | Mahle, T | R | Mahle, T | Colome, A | Ponce de Leon, D | R |
| 6/18/2021 | | @ | TB | L | 2-7 | | Kremer, D | R | Kremer, D | | Wright, K | R |
| 6/19/2021 | | | Hou | W | 7-3 | | Nola, A | R | Nola, A | | Walker, T | R |
| 6/19/2021 | | @ | TB | L | 2-6 | | Allard, K | L | Covey, D | | Canning, G | R |
| 6/21/2021 | | | Sea | L | 3-12 | | Allard, K | L | Allard, K | | Wisler, M | R |
| 6/21/2021 | | @ | Tor | W | 5-2 | | Nola, A | R | Nola, A | Colome, A | Brewer, C | R |
| 6/22/2021 | | | Sea | W | 6-5 | | Musgrove, J | R | Colome, A | | Fedde, E | R |
| 6/22/2021 | | @ | Tor | W | 7-4 | | Mahle, T | R | Mahle, T | Colome, A | Clarke, T | R |
| 6/23/2021 | | | Sea | L | 2-5 | | Mahle, T | R | Farmer, B | | Shoemaker, M | R |
| 6/23/2021 | | @ | Tor | L | 2-5 | | Urena, J | R | Urena, J | | Newcomb, S | L |
| 6/24/2021 | | @ | Bos | L | 0-7 | | Kremer, D | R | Kremer, D | | Plutko, A | R |
| 6/24/2021 | | | Oak | W | 6-4 | | Akin, K | L | Floro, D | Colome, A | Dobnak, R | R |
| 6/25/2021 | | @ | Bos | W | 3-2 | | Allard, K | L | Farmer, B | Colome, A | Kim, K | L |
| 6/25/2021 | | | Oak | W | 10-3 | | Nola, A | R | Nola, A | Colome, A | Clippard, T | R |
| 6/26/2021 | | @ | Bos | L | 0-8 | | Nola, A | R | Nola, A | | Hudson, D | R |
| 6/26/2021 | | | Oak | W | 7-2 | | Allard, K | L | Floro, D | | Fried, M | L |
| 6/28/2021 | | | LAA | L | 2-7 | | Musgrove, J | R | Musgrove, J | | Yarbrough, R | L |
| 6/28/2021 | | @ | NYY | L | 2-3 | | Mahle, T | R | Floro, D | | May, D | R |
| 6/29/2021 | | | LAA | L | 0-6 | | Mahle, T | R | Mahle, T | | Darvish, Y | R |
| 6/29/2021 | | @ | NYY | W | 4-3 | | Urena, J | R | Urena, J | Colome, A | Duffy, D | L |
| 6/30/2021 | | | LAA | L | 1-6 | | Nola, A | R | Nola, A | | Toussaint, T | R |
| 6/30/2021 | | @ | NYY | L | 4-6 | | Kremer, D | R | Covey, D | | Lynn, L | R |
| 7/15/2021 | | @ | Det | W | 6-2 | | Mahle, T | R | Mahle, T | | Marquez, G | R |
| 7/15/2021 | | | KC | W | 3-1 | | Nola, A | R | Nola, A | Colome, A | Lamet, D | R |
| 7/16/2021 | | @ | Det | L | 3-5 | | Urena, J | R | Urena, J | | Bauer, T | R |
| 7/16/2021 | | | KC | W | 9-5 | | Allard, K | L | Covey, D | Floro, D | Voth, A | R |
| 7/17/2021 | | @ | Det | L | 0-4 | | Musgrove, J | R | Musgrove, J | | Lester, J | L |
| 7/17/2021 | | | KC | L | 1-5 | | Musgrove, J | R | Musgrove, J | | Singer, B | R |
| 7/19/2021 | | @ | ChW | L | 1-3 | | Nola, A | R | Nola, A | | Antone, T | R |
| 7/19/2021 | | | Cle | W | 16-0 | | Akin, K | L | Akin, K | Covey, D | Houck, T | R |
| 7/20/2021 | | @ | ChW | W | 4-3 | | Akin, K | L | Leibrandt, B | Colome, A | Freeland, K | L |
| 7/20/2021 | | | Cle | W | 5-3 | | Nola, A | R | Nola, A | Colome, A | Civale, A | R |
| 7/21/2021 | | @ | ChW | L | 11-12 | | Mahle, T | R | Colome, A | | Tanaka, M | R |
| 7/21/2021 | | | Cle | W | 14-4 | | Allard, K | L | Allard, K | | Bielak, B | R |
| 7/22/2021 | | @ | Cle | W | 15-9 | | Urena, J | R | Urena, J | | Sanchez, S | R |
| 7/22/2021 | | | ChW | L | 1-7 | | Musgrove, J | R | Musgrove, J | | Freeland, K | L |
| 7/23/2021 | | @ | Cle | W | 3-2 | | Musgrove, J | R | Musgrove, J | Barnes, M | Shoemaker, M | R |
| 7/23/2021 | | | ChW | L | 7-8 | | Mahle, T | R | Mahle, T | | Odorizzi, J | R |
| 7/24/2021 | | @ | Cle | W | 6-3 | | Nola, A | R | Nola, A | Floro, D | Civale, A | R |
| 7/24/2021 | | | ChW | L | 1-3 | | Nola, A | R | Floro, D | | Peralta, F | R |
| 7/26/2021 | | @ | KC | L | 4-10 | | Akin, K | L | Akin, K | | Arrieta, J | R |
| 7/26/2021 | | | Det | L | 1-4 | | Akin, K | L | Akin, K | | Cody, K | R |
| 7/27/2021 | | @ | KC | W | 9-1 | | Mahle, T | R | Mahle, T | | Voth, A | R |
| 7/27/2021 | | | Det | L | 3-9 | | Allard, K | L | Allard, K | | Bauer, T | R |
| 7/28/2021 | | @ | KC | L | 0-8 | | Urena, J | R | Urena, J | | Lindblom, J | R |
| 7/28/2021 | | | Det | W | 3-1 | | Mahle, T | R | Barnes, M | Colome, A | Lester, J | L |
| 8/13/2021 | | | Bal | W | 15-4 | | Nola, A | R | Nola, A | | Turnbull, S | R |
| 8/13/2021 | | @ | Tex | W | 7-5 | | Kremer, D | R | Reid-Foley, S | Colome, A | Sanchez, A | R |
| 8/14/2021 | | | Bal | L | 2-8 | | Allard, K | L | Allard, K | | Urias, J | L |
| 8/14/2021 | | @ | Tex | L | 1-5 | | Urena, J | R | Urena, J | | Teheran, J | R |
| 8/15/2021 | | | Bal | L | 4-9 | | Musgrove, J | R | Musgrove, J | | Cobb, A | R |
| 8/15/2021 | | @ | Tex | W | 5-2 | | Akin, K | L | Akin, K | Colome, A | Fulmer, M | R |
| 8/16/2021 | | | Bos | L | 0-4 | | Akin, K | L | Akin, K | | Plutko, A | R |
| 8/16/2021 | | @ | Sea | L | 1-7 | | Mahle, T | R | Mahle, T | | Urquidy, J | R |
| 8/17/2021 | | | Bos | L | 3-6 | | Mahle, T | R | Colome, A | | Webb, L | R |
| 8/17/2021 | | @ | Sea | L | 2-3 | | Allard, K | L | Borucki, R | | Fedde, E | R |
| 8/18/2021 | | | Bos | L | 1-8 | | Nola, A | R | Nola, A | | Kim, K | L |
| 8/18/2021 | | @ | Sea | L | 1-5 | | Kremer, D | R | Kremer, D | | Minor, M | L |
| 8/20/2021 | | @ | Hou | W | 6-3 | | Urena, J | R | Urena, J | | Ponce de Leon, D | R |
| 8/20/2021 | | | NYY | W | 3-2 | | Allard, K | L | Allard, K | Colome, A | May, D | R |
| 8/21/2021 | | @ | Hou | L | 4-5 | | Akin, K | L | Akin, K | | Smyly, D | L |
| 8/21/2021 | | | NYY | W | 4-3 | 11 | Musgrove, J | R | Barnes, M | | Duffy, D | L |
| 8/22/2021 | | @ | Hou | W | 7-3 | 17 | Mahle, T | R | Floro, D | DeSclafani, A | Dunn, J | R |
| 8/22/2021 | | | NYY | L | 1-8 | | Mahle, T | R | Mahle, T | | Bundy, D | R |
| 8/23/2021 | | | TB | W | 9-5 | 10 | Akin, K | L | Colome, A | | Miller, T | R |
| 8/23/2021 | | @ | Oak | L | 4-13 | | Allard, K | L | Allard, K | | Cueto, J | R |
| 8/24/2021 | | | TB | W | 4-1 | | Nola, A | R | Nola, A | Colome, A | Smeltzer, D | L |
| 8/24/2021 | | @ | Oak | L | 0-3 | | Kremer, D | R | Kremer, D | | Fried, M | L |
| 8/25/2021 | | | TB | L | 3-5 | | Allard, K | L | Allard, K | | Soroka, M | R |
| 8/25/2021 | | @ | Oak | W | 3-2 | | Urena, J | R | Urena, J | Borucki, R | Anderson, T | L |
| 8/27/2021 | | | Tor | W | 4-3 | | Musgrove, J | R | Colome, A | | Brewer, C | R |
| 8/27/2021 | | @ | LAA | L | 0-1 | 11 | Akin, K | L | Floro, D | | Gomber, A | L |
| 8/28/2021 | | | Tor | W | 9-2 | | Mahle, T | R | Mahle, T | | Roark, T | R |
| 8/28/2021 | | @ | LAA | L | 1-5 | | Mahle, T | R | Farmer, B | | Darvish, Y | R |
| 8/29/2021 | | | Tor | W | 7-6 | | Nola, A | R | Colome, A | | Lorenzen, M | R |
| 8/29/2021 | | @ | LAA | W | 9-7 | | Allard, K | L | Barnes, M | Colome, A | Boyd, M | L |
| 9/13/2021 | | @ | ChW | L | 1-12 | | Musgrove, J | R | Musgrove, J | | Freeland, K | L |
| 9/13/2021 | | | Cle | L | 2-3 | | Nola, A | R | Nola, A | | Sanchez, S | R |
| 9/14/2021 | | @ | ChW | L | 4-5 | | Kremer, D | R | Smith, W | | Tanaka, M | R |
| 9/14/2021 | | | Cle | W | 5-3 | | Allard, K | L | Floro, D | Colome, A | Suarez, J | L |
| 9/15/2021 | | @ | ChW | W | 5-4 | | Nola, A | R | DeSclafani, A | Colome, A | Eovaldi, N | R |
| 9/15/2021 | | | Cle | W | 9-7 | | Musgrove, J | R | DeSclafani, A | Colome, A | Weber, R | R |
| 9/17/2021 | | @ | KC | L | 8-10 | | Akin, K | L | Barnes, M | | Arrieta, J | R |
| 9/17/2021 | | | Det | L | 4-5 | 12 | Akin, K | L | Farmer, B | | Cody, K | R |
| 9/18/2021 | | @ | KC | L | 0-1 | 13 | Urena, J | R | Colome, A | | Lamet, D | R |
| 9/18/2021 | | | Det | L | 2-4 | | Nola, A | R | Nola, A | | Flaherty, J | R |
| 9/19/2021 | | @ | KC | W | 15-2 | | Musgrove, J | R | Musgrove, J | DeSclafani, A | Voth, A | R |
| 9/19/2021 | | | Det | L | 2-5 | | Allard, K | L | Allard, K | | Marquez, G | R |
| 9/20/2021 | | @ | Det | L | 6-9 | | Kremer, D | R | Kremer, D | | Flaherty, J | R |
| 9/20/2021 | | | KC | L | 4-8 | | Musgrove, J | R | Borucki, R | | Singer, B | R |
| 9/21/2021 | | @ | Det | W | 2-1 | | Nola, A | R | Nola, A | Floro, D | Lester, J | L |
| 9/21/2021 | | | KC | W | 11-2 | | Mahle, T | R | Mahle, T | Farmer, B | Lindblom, J | R |
| 9/22/2021 | | @ | Det | L | 2-8 | | Akin, K | L | Akin, K | | Bauer, T | R |
| 9/22/2021 | | | KC | W | 2-1 | | Nola, A | R | Farmer, B | | Lamet, D | R |
| 9/24/2021 | | @ | Cle | W | 7-2 | | Urena, J | R | Urena, J | | Oswalt, C | R |
| 9/24/2021 | | | ChW | L | 4-10 | | Akin, K | L | Akin, K | | Braymer, B | L |
| 9/25/2021 | | @ | Cle | L | 1-6 | | Musgrove, J | R | Musgrove, J | | Suarez, J | L |
| 9/25/2021 | | | ChW | L | 3-4 | | Allard, K | L | Allard, K | | Tanaka, M | R |
| 9/26/2021 | | @ | Cle | W | 5-2 | | Kremer, D | R | Kremer, D | | Weber, R | R |
| 9/26/2021 | | | ChW | L | 4-7 | | Mahle, T | R | Reid-Foley, S | | Freeland, K | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/15/2021 | | @ | Cle | W | Bregman, A | 6 | 1 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/15/2021 | | | ChW | W | Tucker, K | 11 | 5 | 2 | 0 | 1.000 | 2-0 | W2 | 2 |
| 4/16/2021 | | @ | Cle | L | | 0 | 3 | 2 | 1 | .667 | 2-1 | L1 | 3 |
| 4/16/2021 | | | ChW | L | | 4 | 7 | 2 | 2 | .500 | 2-2 | L2 | 4 |
| 4/17/2021 | | @ | Cle | W | Swanson, D | 7 | 4 | 3 | 2 | .600 | 3-2 | W1 | 5 |
| 4/17/2021 | | | ChW | W | Freeman, F | 6 | 3 | 4 | 2 | .667 | 4-2 | W2 | 6 |
| 4/19/2021 | | @ | Det | W | Bregman, A | 4 | 2 | 5 | 2 | .714 | 5-2 | W3 | 7 |
| 4/19/2021 | | | KC | W | Lopez, N | 7 | 2 | 6 | 2 | .750 | 6-2 | W4 | 8 |
| 4/20/2021 | | @ | Det | L | | 2 | 16 | 6 | 3 | .667 | 6-3 | L1 | 9 |
| 4/20/2021 | | | KC | W | Swanson, D | 2 | 0 | 7 | 3 | .700 | 7-3 | W1 | 10 |
| 4/21/2021 | | @ | Det | W | Tucker, K | 5 | 4 | 8 | 3 | .727 | 7-3 | W2 | 11 |
| 4/21/2021 | | | KC | L | | 2 | 4 | 8 | 4 | .667 | 6-4 | L1 | 12 |
| 4/22/2021 | | @ | KC | W | Freeman, F | 3 | 1 | 9 | 4 | .692 | 7-3 | W1 | 13 |
| 4/22/2021 | | | Det | W | Hays, A | 3 | 1 | 10 | 4 | .714 | 8-2 | W2 | 14 |
| 4/23/2021 | | @ | KC | L | | 2 | 6 | 10 | 5 | .667 | 7-3 | L1 | 15 |
| 4/23/2021 | | | Det | L | | 4 | 5 | 10 | 6 | .625 | 6-4 | L2 | 16 |
| 4/24/2021 | | @ | KC | W | Freeman, F | 2 | 1 | 11 | 6 | .647 | 6-4 | W1 | 17 |
| 4/24/2021 | | | Det | W | Hays, A | 3 | 0 | 12 | 6 | .667 | 6-4 | W2 | 18 |
| 4/26/2021 | | @ | ChW | W | Narvaez, O | 1 | 0 | 13 | 6 | .684 | 7-3 | W3 | 19 |
| 4/26/2021 | | | Cle | L | | 3 | 7 | 13 | 7 | .650 | 6-4 | L1 | 20 |
| 4/27/2021 | | @ | ChW | L | | 2 | 7 | 13 | 8 | .619 | 5-5 | L2 | 21 |
| 4/27/2021 | | | Cle | W | Freeman, F | 5 | 4 | 14 | 8 | .636 | 6-4 | W1 | 22 |
| 4/28/2021 | | @ | ChW | L | | 0 | 4 | 14 | 9 | .609 | 5-5 | L1 | 23 |
| 4/28/2021 | | | Cle | W | | 6 | 2 | 15 | 9 | .625 | 5-5 | W1 | 24 |
| 5/13/2021 | | @ | SD | W | Riley, A | 6 | 1 | 16 | 9 | .640 | 6-4 | W2 | 25 |
| 5/13/2021 | | | Phi | W | Hays, A | 6 | 3 | 17 | 9 | .654 | 7-3 | W3 | 26 |
| 5/14/2021 | | @ | SD | W | Lopez, N | 3 | 2 | 18 | 9 | .667 | 7-3 | W4 | 27 |
| 5/14/2021 | | | Phi | W | Riley, A | 2 | 1 | 19 | 9 | .679 | 7-3 | W5 | 28 |
| 5/15/2021 | | @ | SD | L | | 6 | 8 | 19 | 10 | .655 | 6-4 | L1 | 29 |
| 5/15/2021 | | | Phi | W | Bregman, A | 8 | 3 | 20 | 10 | .667 | 7-3 | W1 | 30 |
| 5/17/2021 | | | NYM | W | Bregman, A | 12 | 2 | 21 | 10 | .677 | 8-2 | W2 | 31 |
| 5/17/2021 | | @ | Ari | L | | 5 | 6 | 21 | 11 | .656 | 7-3 | L1 | 32 |
| 5/18/2021 | | | NYM | L | | 2 | 5 | 21 | 12 | .636 | 7-3 | L2 | 33 |
| 5/18/2021 | | @ | Ari | L | | 0 | 7 | 21 | 13 | .618 | 6-4 | L3 | 34 |
| 5/19/2021 | | | NYM | L | | 0 | 2 | 21 | 14 | .600 | 5-5 | L4 | 35 |
| 5/19/2021 | | @ | Ari | L | | 0 | 1 | 21 | 15 | .583 | 4-6 | L5 | 36 |
| 5/21/2021 | | | Mia | W | Riley, A | 2 | 0 | 22 | 15 | .595 | 4-6 | W1 | 37 |
| 5/21/2021 | | @ | Col | L | | 6 | 11 | 22 | 16 | .579 | 3-7 | L1 | 38 |
| 5/22/2021 | | | Mia | L | | 4 | 6 | 22 | 17 | .564 | 3-7 | L2 | 39 |
| 5/22/2021 | | @ | Col | L | | 3 | 4 | 22 | 18 | .550 | 2-8 | L3 | 40 |
| 5/23/2021 | | | Mia | W | Hays, A | 8 | 4 | 23 | 18 | .561 | 2-8 | W1 | 41 |
| 5/23/2021 | | @ | Col | L | | 2 | 5 | 23 | 19 | .548 | 2-8 | L1 | 42 |
| 5/24/2021 | | @ | LAD | W | Hays, A | 8 | 7 | 24 | 19 | .558 | 3-7 | W1 | 43 |
| 5/24/2021 | | | Was | W | Riley, A | 4 | 1 | 25 | 19 | .568 | 4-6 | W2 | 44 |
| 5/25/2021 | | @ | LAD | L | | 1 | 5 | 25 | 20 | .556 | 4-6 | L1 | 45 |
| 5/25/2021 | | | Was | L | | 0 | 4 | 25 | 21 | .543 | 4-6 | L2 | 46 |
| 5/26/2021 | | @ | LAD | L | | 3 | 12 | 25 | 22 | .532 | 3-7 | L3 | 47 |
| 5/26/2021 | | | Was | W | Bregman, A | 2 | 0 | 26 | 22 | .542 | 4-6 | W1 | 48 |
| 5/28/2021 | | @ | SF | W | | 5 | 1 | 27 | 22 | .551 | 5-5 | W2 | 49 |
| 5/28/2021 | | | Atl | L | | 4 | 5 | 27 | 23 | .540 | 5-5 | L1 | 50 |
| 5/29/2021 | | @ | SF | W | Riley, A | 8 | 4 | 28 | 23 | .549 | 5-5 | W1 | 51 |
| 5/29/2021 | | | Atl | W | Lopez, N | 1 | 0 | 29 | 23 | .558 | 6-4 | W2 | 52 |
| 5/30/2021 | | @ | SF | L | | 6 | 7 | 29 | 24 | .547 | 5-5 | L1 | 53 |
| 5/30/2021 | | | Atl | W | Swanson, D | 10 | 9 | 30 | 24 | .556 | 5-5 | W1 | 54 |
| 6/14/2021 | | @ | Bal | L | | 4 | 8 | 30 | 25 | .545 | 5-5 | L1 | 55 |
| 6/14/2021 | | | Tex | L | | 0 | 5 | 30 | 26 | .536 | 5-5 | L2 | 56 |
| 6/15/2021 | | @ | Bal | W | Lopez, N | 7 | 3 | 31 | 26 | .544 | 6-4 | W1 | 57 |
| 6/15/2021 | | | Tex | W | Riley, A | 4 | 3 | 32 | 26 | .552 | 6-4 | W2 | 58 |
| 6/16/2021 | | @ | Bal | L | | 6 | 8 | 32 | 27 | .542 | 5-5 | L1 | 59 |
| 6/16/2021 | | | Tex | W | Bregman, A | 10 | 1 | 33 | 27 | .550 | 6-4 | W1 | 60 |
| 6/17/2021 | | | Hou | W | Bregman, A | 2 | 0 | 34 | 27 | .557 | 6-4 | W2 | 61 |
| 6/17/2021 | | @ | TB | W | Riley, A | 13 | 0 | 35 | 27 | .565 | 6-4 | W3 | 62 |
| 6/18/2021 | | | Hou | W | Swanson, D | 2 | 1 | 36 | 27 | .571 | 7-3 | W4 | 63 |
| 6/18/2021 | | @ | TB | L | | 2 | 7 | 36 | 28 | .563 | 6-4 | L1 | 64 |
| 6/19/2021 | | | Hou | W | Tucker, K | 7 | 3 | 37 | 28 | .569 | 7-3 | W1 | 65 |
| 6/19/2021 | | @ | TB | L | | 2 | 6 | 37 | 29 | .561 | 7-3 | L1 | 66 |
| 6/21/2021 | | | Sea | L | | 3 | 12 | 37 | 30 | .552 | 6-4 | L2 | 67 |
| 6/21/2021 | | @ | Tor | W | Freeman, F | 5 | 2 | 38 | 30 | .559 | 6-4 | W1 | 68 |
| 6/22/2021 | | | Sea | W | Hays, A | 6 | 5 | 39 | 30 | .565 | 7-3 | W2 | 69 |
| 6/22/2021 | | @ | Tor | W | Tucker, K | 7 | 4 | 40 | 30 | .571 | 7-3 | W3 | 70 |
| 6/23/2021 | | | Sea | L | | 2 | 5 | 40 | 31 | .563 | 6-4 | L1 | 71 |
| 6/23/2021 | | @ | Tor | L | | 2 | 5 | 40 | 32 | .556 | 5-5 | L2 | 72 |
| 6/24/2021 | | @ | Bos | L | | 0 | 7 | 40 | 33 | .548 | 4-6 | L3 | 73 |
| 6/24/2021 | | | Oak | W | Riley, A | 6 | 4 | 41 | 33 | .554 | 5-5 | W1 | 74 |
| 6/25/2021 | | @ | Bos | W | Camargo, J | 3 | 2 | 42 | 33 | .560 | 5-5 | W2 | 75 |
| 6/25/2021 | | | Oak | W | Riley, A | 10 | 3 | 43 | 33 | .566 | 6-4 | W3 | 76 |
| 6/26/2021 | | @ | Bos | L | | 0 | 8 | 43 | 34 | .558 | 6-4 | L1 | 77 |
| 6/26/2021 | | | Oak | W | Riley, A | 7 | 2 | 44 | 34 | .564 | 6-4 | W1 | 78 |
| 6/28/2021 | | | LAA | L | | 2 | 7 | 44 | 35 | .557 | 5-5 | L1 | 79 |
| 6/28/2021 | | @ | NYY | L | | 2 | 3 | 44 | 36 | .550 | 4-6 | L2 | 80 |
| 6/29/2021 | | | LAA | L | | 0 | 6 | 44 | 37 | .543 | 4-6 | L3 | 81 |
| 6/29/2021 | | @ | NYY | W | Tucker, K | 4 | 3 | 45 | 37 | .549 | 5-5 | W1 | 82 |
| 6/30/2021 | | | LAA | L | | 1 | 6 | 45 | 38 | .542 | 5-5 | L1 | 83 |
| 6/30/2021 | | @ | NYY | L | | 4 | 6 | 45 | 39 | .536 | 4-6 | L2 | 84 |
| 7/15/2021 | | @ | Det | W | Tucker, K | 6 | 2 | 46 | 39 | .541 | 4-6 | W1 | 85 |
| 7/15/2021 | | | KC | W | Verdugo, A | 3 | 1 | 47 | 39 | .547 | 4-6 | W2 | 86 |
| 7/16/2021 | | @ | Det | L | | 3 | 5 | 47 | 40 | .540 | 4-6 | L1 | 87 |
| 7/16/2021 | | | KC | W | Lopez, N | 9 | 5 | 48 | 40 | .545 | 4-6 | W1 | 88 |
| 7/17/2021 | | @ | Det | L | | 0 | 4 | 48 | 41 | .539 | 4-6 | L1 | 89 |
| 7/17/2021 | | | KC | L | | 1 | 5 | 48 | 42 | .533 | 4-6 | L2 | 90 |
| 7/19/2021 | | @ | ChW | L | | 1 | 3 | 48 | 43 | .527 | 4-6 | L3 | 91 |
| 7/19/2021 | | | Cle | W | Tucker, K | 16 | 0 | 49 | 43 | .533 | 4-6 | W1 | 92 |
| 7/20/2021 | | @ | ChW | W | Lopez, N | 4 | 3 | 50 | 43 | .538 | 5-5 | W2 | 93 |
| 7/20/2021 | | | Cle | W | Hays, A | 5 | 3 | 51 | 43 | .543 | 6-4 | W3 | 94 |
| 7/21/2021 | | @ | ChW | L | | 11 | 12 | 51 | 44 | .537 | 5-5 | L1 | 95 |
| 7/21/2021 | | | Cle | W | Swanson, D | 14 | 4 | 52 | 44 | .542 | 5-5 | W1 | 96 |
| 7/22/2021 | | @ | Cle | W | Tucker, K | 15 | 9 | 53 | 44 | .546 | 6-4 | W2 | 97 |
| 7/22/2021 | | | ChW | L | | 1 | 7 | 53 | 45 | .541 | 5-5 | L1 | 98 |
| 7/23/2021 | | @ | Cle | W | Tucker, K | 3 | 2 | 54 | 45 | .545 | 6-4 | W1 | 99 |
| 7/23/2021 | | | ChW | L | | 7 | 8 | 54 | 46 | .540 | 6-4 | L1 | 100 |
| 7/24/2021 | | @ | Cle | W | Freeman, F | 6 | 3 | 55 | 46 | .545 | 7-3 | W1 | 101 |
| 7/24/2021 | | | ChW | L | | 1 | 3 | 55 | 47 | .539 | 6-4 | L1 | 102 |
| 7/26/2021 | | @ | KC | L | | 4 | 10 | 55 | 48 | .534 | 5-5 | L2 | 103 |
| 7/26/2021 | | | Det | L | | 1 | 4 | 55 | 49 | .529 | 4-6 | L3 | 104 |
| 7/27/2021 | | @ | KC | W | Tucker, K | 9 | 1 | 56 | 49 | .533 | 5-5 | W1 | 105 |
| 7/27/2021 | | | Det | L | | 3 | 9 | 56 | 50 | .528 | 4-6 | L1 | 106 |
| 7/28/2021 | | @ | KC | L | | 0 | 8 | 56 | 51 | .523 | 3-7 | L2 | 107 |
| 7/28/2021 | | | Det | W | Verdugo, A | 3 | 1 | 57 | 51 | .528 | 4-6 | W1 | 108 |
| 8/13/2021 | | | Bal | W | Bregman, A | 15 | 4 | 58 | 51 | .532 | 4-6 | W2 | 109 |
| 8/13/2021 | | @ | Tex | W | Verdugo, A | 7 | 5 | 59 | 51 | .536 | 5-5 | W3 | 110 |
| 8/14/2021 | | | Bal | L | | 2 | 8 | 59 | 52 | .532 | 4-6 | L1 | 111 |
| 8/14/2021 | | @ | Tex | L | | 1 | 5 | 59 | 53 | .527 | 4-6 | L2 | 112 |
| 8/15/2021 | | | Bal | L | | 4 | 9 | 59 | 54 | .522 | 4-6 | L3 | 113 |
| 8/15/2021 | | @ | Tex | W | Torrens, L | 5 | 2 | 60 | 54 | .526 | 5-5 | W1 | 114 |
| 8/16/2021 | | | Bos | L | | 0 | 4 | 60 | 55 | .522 | 4-6 | L1 | 115 |
| 8/16/2021 | | @ | Sea | L | | 1 | 7 | 60 | 56 | .517 | 4-6 | L2 | 116 |
| 8/17/2021 | | | Bos | L | | 3 | 6 | 60 | 57 | .513 | 4-6 | L3 | 117 |
| 8/17/2021 | | @ | Sea | L | | 2 | 3 | 60 | 58 | .508 | 3-7 | L4 | 118 |
| 8/18/2021 | | | Bos | L | | 1 | 8 | 60 | 59 | .504 | 2-8 | L5 | 119 |
| 8/18/2021 | | @ | Sea | L | | 1 | 5 | 60 | 60 | .500 | 1-9 | L6 | 120 |
| 8/20/2021 | | @ | Hou | W | Freeman, F | 6 | 3 | 61 | 60 | .504 | 2-8 | W1 | 121 |
| 8/20/2021 | | | NYY | W | Riley, A | 3 | 2 | 62 | 60 | .508 | 3-7 | W2 | 122 |
| 8/21/2021 | | @ | Hou | L | | 4 | 5 | 62 | 61 | .504 | 3-7 | L1 | 123 |
| 8/21/2021 | | | NYY | W | Verdugo, A | 4 | 3 | 63 | 61 | .508 | 3-7 | W1 | 124 |
| 8/22/2021 | | @ | Hou | W | Swanson, D | 7 | 3 | 64 | 61 | .512 | 4-6 | W2 | 125 |
| 8/22/2021 | | | NYY | L | | 1 | 8 | 64 | 62 | .508 | 4-6 | L1 | 126 |
| 8/23/2021 | | | TB | W | Tucker, K | 9 | 5 | 65 | 62 | .512 | 5-5 | W1 | 127 |
| 8/23/2021 | | @ | Oak | L | | 4 | 13 | 65 | 63 | .508 | 5-5 | L1 | 128 |
| 8/24/2021 | | | TB | W | Caratini, V | 4 | 1 | 66 | 63 | .512 | 6-4 | W1 | 129 |
| 8/24/2021 | | @ | Oak | L | | 0 | 3 | 66 | 64 | .508 | 6-4 | L1 | 130 |
| 8/25/2021 | | | TB | L | | 3 | 5 | 66 | 65 | .504 | 5-5 | L2 | 131 |
| 8/25/2021 | | @ | Oak | W | Torrens, L | 3 | 2 | 67 | 65 | .508 | 5-5 | W1 | 132 |
| 8/27/2021 | | | Tor | W | Freeman, F | 4 | 3 | 68 | 65 | .511 | 6-4 | W2 | 133 |
| 8/27/2021 | | @ | LAA | L | | 0 | 1 | 68 | 66 | .507 | 5-5 | L1 | 134 |
| 8/28/2021 | | | Tor | W | Tucker, K | 9 | 2 | 69 | 66 | .511 | 5-5 | W1 | 135 |
| 8/28/2021 | | @ | LAA | L | | 1 | 5 | 69 | 67 | .507 | 5-5 | L1 | 136 |
| 8/29/2021 | | | Tor | W | Verdugo, A | 7 | 6 | 70 | 67 | .511 | 5-5 | W1 | 137 |
| 8/29/2021 | | @ | LAA | W | Freeman, F | 9 | 7 | 71 | 67 | .514 | 6-4 | W2 | 138 |
| 9/13/2021 | | @ | ChW | L | | 1 | 12 | 71 | 68 | .511 | 5-5 | L1 | 139 |
| 9/13/2021 | | | Cle | L | | 2 | 3 | 71 | 69 | .507 | 5-5 | L2 | 140 |
| 9/14/2021 | | @ | ChW | L | | 4 | 5 | 71 | 70 | .504 | 5-5 | L3 | 141 |
| 9/14/2021 | | | Cle | W | Verdugo, A | 5 | 3 | 72 | 70 | .507 | 5-5 | W1 | 142 |
| 9/15/2021 | | @ | ChW | W | Bregman, A | 5 | 4 | 73 | 70 | .510 | 5-5 | W2 | 143 |
| 9/15/2021 | | | Cle | W | Caratini, V | 9 | 7 | 74 | 70 | .514 | 6-4 | W3 | 144 |
| 9/17/2021 | | @ | KC | L | | 8 | 10 | 74 | 71 | .510 | 5-5 | L1 | 145 |
| 9/17/2021 | | | Det | L | | 4 | 5 | 74 | 72 | .507 | 5-5 | L2 | 146 |
| 9/18/2021 | | @ | KC | L | | 0 | 1 | 74 | 73 | .503 | 4-6 | L3 | 147 |
| 9/18/2021 | | | Det | L | | 2 | 4 | 74 | 74 | .500 | 3-7 | L4 | 148 |
| 9/19/2021 | | @ | KC | W | Freeman, F | 15 | 2 | 75 | 74 | .503 | 4-6 | W1 | 149 |
| 9/19/2021 | | | Det | L | | 2 | 5 | 75 | 75 | .500 | 4-6 | L1 | 150 |
| 9/20/2021 | | @ | Det | L | | 6 | 9 | 75 | 76 | .497 | 4-6 | L2 | 151 |
| 9/20/2021 | | | KC | L | | 4 | 8 | 75 | 77 | .493 | 3-7 | L3 | 152 |
| 9/21/2021 | | @ | Det | W | Bregman, A | 2 | 1 | 76 | 77 | .497 | 3-7 | W1 | 153 |
| 9/21/2021 | | | KC | W | Bregman, A | 11 | 2 | 77 | 77 | .500 | 3-7 | W2 | 154 |
| 9/22/2021 | | @ | Det | L | | 2 | 8 | 77 | 78 | .497 | 3-7 | L1 | 155 |
| 9/22/2021 | | | KC | W | Tucker, K | 2 | 1 | 78 | 78 | .500 | 4-6 | W1 | 156 |
| 9/24/2021 | | @ | Cle | W | Swanson, D | 7 | 2 | 79 | 78 | .503 | 5-5 | W2 | 157 |
| 9/24/2021 | | | ChW | L | | 4 | 10 | 79 | 79 | .500 | 5-5 | L1 | 158 |
| 9/25/2021 | | @ | Cle | L | | 1 | 6 | 79 | 80 | .497 | 4-6 | L2 | 159 |
| 9/25/2021 | | | ChW | L | | 3 | 4 | 79 | 81 | .494 | 4-6 | L3 | 160 |
| 9/26/2021 | | @ | Cle | W | Riley, A | 5 | 2 | 80 | 81 | .497 | 5-5 | W1 | 161 |
| 9/26/2021 | | | ChW | L | | 4 | 7 | 80 | 82 | .494 | 5-5 | L1 | 162 |