Team game results - 2021 Cleveland Indians
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/15/2021 | | | Min | L | 1-6 | | Civale, A | R | Civale, A | | Urena, J | R |
| 4/15/2021 | | @ | Det | L | 2-4 | | Civale, A | R | Civale, A | | Lester, J | L |
| 4/16/2021 | | | Min | W | 3-0 | | Keller, B | R | Keller, B | | Nola, A | R |
| 4/16/2021 | | @ | Det | W | 5-2 | | Keller, B | R | Keller, B | Martin, C | Marquez, G | R |
| 4/17/2021 | | | Min | L | 4-7 | | Sanchez, S | R | Hembree, H | | Musgrove, J | R |
| 4/17/2021 | | @ | Det | W | 1-0 | | Sanchez, S | R | Sanchez, S | Claudio, A | Cody, K | R |
| 4/19/2021 | | | ChW | W | 6-3 | | Weber, R | R | Weber, R | Martin, C | Eovaldi, N | R |
| 4/19/2021 | | @ | KC | W | 9-1 | | Weber, R | R | Weber, R | | Arrieta, J | R |
| 4/20/2021 | | | ChW | W | 6-5 | 13 | Civale, A | R | Fry, J | | Weaver, L | R |
| 4/20/2021 | | @ | KC | L | 0-2 | | Civale, A | R | Civale, A | | Lamet, D | R |
| 4/21/2021 | | | ChW | L | 6-8 | 10 | Keller, B | R | Hembree, H | | Freeland, K | L |
| 4/21/2021 | | @ | KC | L | 9-10 | 10 | Keller, B | R | Fry, J | | Rogers, T | L |
| 4/22/2021 | | @ | ChW | L | 1-4 | | Sanchez, S | R | Sanchez, S | | Keller, M | R |
| 4/22/2021 | | | KC | W | 8-7 | | Sanchez, S | R | Roe, C | | Singer, B | R |
| 4/23/2021 | | @ | ChW | L | 6-7 | | Castano, D | L | Lockett, W | | Eovaldi, N | R |
| 4/23/2021 | | | KC | W | 16-7 | | Castano, D | L | Castano, D | | Lindblom, J | R |
| 4/24/2021 | | @ | ChW | L | 2-4 | | Civale, A | R | Civale, A | | Tanaka, M | R |
| 4/24/2021 | | | KC | L | 4-11 | | Civale, A | R | Civale, A | | Lamet, D | R |
| 4/26/2021 | | | Det | L | 2-13 | | Weber, R | R | Weber, R | | Marquez, G | R |
| 4/26/2021 | | @ | Min | W | 7-3 | | Weber, R | R | Weber, R | Roe, C | Akin, K | L |
| 4/27/2021 | | | Det | L | 0-5 | | Keller, B | R | Keller, B | | Cody, K | R |
| 4/27/2021 | | @ | Min | L | 4-5 | | Keller, B | R | Keller, B | | Allard, K | L |
| 4/28/2021 | | | Det | W | 7-3 | | Castano, D | L | Castano, D | | Parker, B | R |
| 4/28/2021 | | @ | Min | L | 2-6 | | Castano, D | L | Castano, D | | Mahle, T | R |
| 5/13/2021 | | | Atl | W | 2-0 | | Sanchez, S | R | Sanchez, S | Martin, C | Milone, T | L |
| 5/13/2021 | | @ | Col | L | 1-5 | | Sanchez, S | R | Sanchez, S | | Wainwright, A | R |
| 5/14/2021 | | | Atl | L | 2-6 | | Civale, A | R | Civale, A | | Barria, J | R |
| 5/14/2021 | | @ | Col | L | 2-6 | | Civale, A | R | Civale, A | | Bieber, S | R |
| 5/15/2021 | | | Atl | W | 8-1 | | Keller, B | R | Keller, B | | Corbin, P | L |
| 5/15/2021 | | @ | Col | L | 4-6 | | Keller, B | R | Keller, B | | Cole, G | R |
| 5/17/2021 | | @ | LAD | L | 2-7 | | Weber, R | R | Claudio, A | | Houser, A | R |
| 5/17/2021 | | | Phi | L | 3-7 | | Weber, R | R | Lockett, W | | Manaea, S | L |
| 5/18/2021 | | @ | LAD | W | 4-3 | | Sanchez, S | R | Sanchez, S | Martin, C | Porcello, R | R |
| 5/18/2021 | | | Phi | L | 0-2 | | Sanchez, S | R | Roe, C | | Castillo, L | R |
| 5/19/2021 | | @ | LAD | L | 3-7 | | Castano, D | L | Castano, D | | Lopez, P | R |
| 5/19/2021 | | | Phi | W | 5-2 | | Castano, D | L | Doolittle, S | Martin, C | Hernandez, E | R |
| 5/21/2021 | | @ | SF | W | 5-0 | | Civale, A | R | Civale, A | | Wheeler, Z | R |
| 5/21/2021 | | | NYM | W | 14-3 | | Civale, A | R | Civale, A | | Mengden, D | R |
| 5/22/2021 | | @ | SF | W | 2-0 | | Keller, B | R | Keller, B | Martin, C | Peterson, D | L |
| 5/22/2021 | | | NYM | W | 2-1 | | Keller, B | R | Keller, B | Martin, C | Luzardo, J | L |
| 5/23/2021 | | @ | SF | W | 4-1 | | Sanchez, S | R | Sanchez, S | Martin, C | Anderson, I | R |
| 5/23/2021 | | | NYM | W | 9-6 | | Sanchez, S | R | Sanchez, S | Roe, C | Gonzalez, G | L |
| 5/24/2021 | | @ | SD | L | 5-19 | | Weber, R | R | Weber, R | | Gausman, K | R |
| 5/24/2021 | | | Mia | L | 1-7 | | Weber, R | R | Weber, R | | Benjamin, W | L |
| 5/25/2021 | | @ | SD | L | 3-5 | | Castano, D | L | Castano, D | | Cease, D | R |
| 5/25/2021 | | | Mia | L | 1-6 | | Castano, D | L | Castano, D | | Fleming, J | L |
| 5/26/2021 | | @ | SD | L | 1-15 | | Civale, A | R | Civale, A | | Giolito, L | R |
| 5/26/2021 | | | Mia | L | 1-5 | | Civale, A | R | Civale, A | | Valdez, F | L |
| 5/28/2021 | | | Was | L | 8-14 | | Keller, B | R | Keller, B | | Bassitt, C | R |
| 5/28/2021 | | @ | Ari | W | 3-2 | | Keller, B | R | Keller, B | Martin, C | Gray, S | R |
| 5/29/2021 | | | Was | L | 2-3 | | Sanchez, S | R | Lockett, W | | Kelly, M | R |
| 5/29/2021 | | @ | Ari | W | 4-3 | | Sanchez, S | R | Claudio, A | | Ryu, H | L |
| 5/30/2021 | | | Was | W | 9-8 | | Castano, D | L | Martin, C | | Gsellman, R | R |
| 5/30/2021 | | @ | Ari | L | 7-8 | | Castano, D | L | Claudio, A | | Gallen, Z | R |
| 6/14/2021 | | | LAA | L | 3-4 | | Civale, A | R | Civale, A | | Darvish, Y | R |
| 6/14/2021 | | @ | Tor | W | 10-3 | | Civale, A | R | Civale, A | | Roark, T | R |
| 6/15/2021 | | | LAA | W | 2-0 | | Keller, B | R | Keller, B | Martin, C | Bumgarner, M | L |
| 6/15/2021 | | @ | Tor | L | 3-4 | 10 | Keller, B | R | Fry, J | | Brewer, C | R |
| 6/16/2021 | | | LAA | L | 5-9 | | Zimmermann, J | R | Zimmermann, J | | Yarbrough, R | L |
| 6/16/2021 | | @ | Tor | L | 2-9 | | Zimmermann, J | R | Zimmermann, J | | Clarke, T | R |
| 6/17/2021 | | @ | Bos | L | 3-4 | | Weber, R | R | Martin, C | | Plutko, A | R |
| 6/17/2021 | | | Tex | W | 6-3 | | Weber, R | R | Weber, R | | Teheran, J | R |
| 6/18/2021 | | @ | Bos | L | 3-5 | | Bielak, B | R | Bielak, B | | Webb, L | R |
| 6/18/2021 | | | Tex | W | 7-2 | | Bielak, B | R | Bielak, B | | Fulmer, M | R |
| 6/19/2021 | | @ | Bos | L | 4-8 | | Civale, A | R | Civale, A | | Kim, K | L |
| 6/19/2021 | | | Tex | W | 14-4 | | Civale, A | R | Civale, A | | Crowe, W | R |
| 6/21/2021 | | | Hou | W | 5-1 | | Keller, B | R | Keller, B | | Dunn, J | R |
| 6/21/2021 | | @ | NYY | L | 0-1 | | Keller, B | R | Keller, B | | Bundy, D | R |
| 6/22/2021 | | | Hou | W | 6-0 | | Zimmermann, J | R | Zimmermann, J | Claudio, A | Gray, J | R |
| 6/22/2021 | | @ | NYY | L | 8-10 | | Zimmermann, J | R | Zimmermann, J | | Duffy, D | L |
| 6/23/2021 | | | Hou | W | 11-4 | | Bielak, B | R | Claudio, A | | Hill, R | L |
| 6/23/2021 | | @ | NYY | L | 1-2 | | Bielak, B | R | Perez, C | | May, D | R |
| 6/24/2021 | | @ | Bal | L | 2-5 | | Weber, R | R | Weber, R | | Cahill, T | R |
| 6/24/2021 | | | Sea | L | 4-6 | | Weber, R | R | Weber, R | | Minor, M | L |
| 6/25/2021 | | @ | Bal | L | 3-4 | 13 | Civale, A | R | Roe, C | | Turnbull, S | R |
| 6/25/2021 | | | Sea | L | 2-3 | 13 | Civale, A | R | Fry, J | | Urquidy, J | R |
| 6/26/2021 | | @ | Bal | L | 3-6 | | Keller, B | R | Fry, J | | Mills, A | R |
| 6/26/2021 | | | Sea | L | 0-2 | | Keller, B | R | Keller, B | | Wisler, M | R |
| 6/28/2021 | | | Oak | L | 4-7 | | Zimmermann, J | R | Zimmermann, J | | Scherzer, M | R |
| 6/28/2021 | | @ | TB | W | 6-2 | | Zimmermann, J | R | Zimmermann, J | | Anderson, B | L |
| 6/29/2021 | | | Oak | W | 7-4 | | Bielak, B | R | Fry, J | Martin, C | Dobnak, R | R |
| 6/29/2021 | | @ | TB | W | 9-4 | | Bielak, B | R | Perez, C | | Wright, K | R |
| 6/30/2021 | | | Oak | L | 6-9 | | Weber, R | R | Hembree, H | | Cueto, J | R |
| 6/30/2021 | | @ | TB | L | 5-7 | | Civale, A | R | Civale, A | | Canning, G | R |
| 7/15/2021 | | | ChW | L | 2-13 | | Civale, A | R | Civale, A | | Weaver, L | R |
| 7/15/2021 | | @ | KC | L | 2-8 | | Civale, A | R | Civale, A | | Lamet, D | R |
| 7/16/2021 | | | ChW | L | 3-5 | | Bielak, B | R | Bielak, B | | Freeland, K | L |
| 7/16/2021 | | @ | KC | L | 2-15 | | Bielak, B | R | Bielak, B | | Voth, A | R |
| 7/17/2021 | | | ChW | L | 7-9 | | Sanchez, S | R | Fry, J | | Odorizzi, J | R |
| 7/17/2021 | | @ | KC | L | 0-3 | | Sanchez, S | R | Sanchez, S | | Singer, B | R |
| 7/19/2021 | | | Det | W | 7-4 | | Houck, T | R | Oswalt, C | Fry, J | Marquez, G | R |
| 7/19/2021 | | @ | Min | L | 0-16 | | Houck, T | R | Houck, T | | Akin, K | L |
| 7/20/2021 | | | Det | L | 0-9 | | Civale, A | R | Civale, A | | Cody, K | R |
| 7/20/2021 | | @ | Min | L | 3-5 | | Civale, A | R | Civale, A | | Nola, A | R |
| 7/21/2021 | | | Det | L | 3-9 | | Bielak, B | R | Bielak, B | | Lester, J | L |
| 7/21/2021 | | @ | Min | L | 4-14 | | Bielak, B | R | Bielak, B | | Allard, K | L |
| 7/22/2021 | | | Min | L | 9-15 | | Sanchez, S | R | Sanchez, S | | Urena, J | R |
| 7/22/2021 | | @ | Det | L | 0-8 | | Sanchez, S | R | Sanchez, S | | Lester, J | L |
| 7/23/2021 | | | Min | L | 2-3 | | Shoemaker, M | R | McGowin, K | | Musgrove, J | R |
| 7/23/2021 | | @ | Det | L | 1-3 | | Shoemaker, M | R | Shoemaker, M | | Cody, K | R |
| 7/24/2021 | | | Min | L | 3-6 | | Civale, A | R | Civale, A | | Nola, A | R |
| 7/24/2021 | | @ | Det | L | 2-7 | | Civale, A | R | Civale, A | | Marquez, G | R |
| 7/26/2021 | | @ | ChW | L | 3-7 | | Houck, T | R | Houck, T | | Antone, T | R |
| 7/26/2021 | | | KC | W | 6-5 | 11 | Houck, T | R | Doolittle, S | | Arrieta, J | R |
| 7/27/2021 | | @ | ChW | L | 6-7 | | Bielak, B | R | Fry, J | | Tanaka, M | R |
| 7/27/2021 | | | KC | L | 12-17 | | Bielak, B | R | Doolittle, S | | Voth, A | R |
| 7/28/2021 | | @ | ChW | L | 7-9 | | Shoemaker, M | R | Weber, R | | Eovaldi, N | R |
| 7/28/2021 | | | KC | W | 9-6 | | Shoemaker, M | R | Bacus, D | Weber, R | Lindblom, J | R |
| 8/13/2021 | | @ | Hou | L | 1-3 | | Civale, A | R | Civale, A | | Walker, T | R |
| 8/13/2021 | | | Tor | L | 3-13 | | Civale, A | R | Civale, A | | Lorenzen, M | R |
| 8/14/2021 | | @ | Hou | L | 4-5 | | Bielak, B | R | Bielak, B | | Ponce de Leon, D | R |
| 8/14/2021 | | | Tor | L | 5-9 | | Bielak, B | R | Bielak, B | | Newcomb, S | L |
| 8/15/2021 | | @ | Hou | L | 0-5 | | Castano, D | L | Castano, D | | Smyly, D | L |
| 8/15/2021 | | | Tor | L | 5-17 | | Castano, D | L | Castano, D | | Miley, W | L |
| 8/16/2021 | | | Bal | L | 3-14 | | Houck, T | R | Houck, T | | Mills, A | R |
| 8/16/2021 | | @ | Oak | L | 0-8 | | Houck, T | R | Houck, T | | Cueto, J | R |
| 8/17/2021 | | | Bal | L | 1-3 | 11 | Shoemaker, M | R | Fry, J | | Lopez, J | R |
| 8/17/2021 | | @ | Oak | L | 0-1 | | Shoemaker, M | R | Fry, J | | Dobnak, R | R |
| 8/18/2021 | | | Bal | L | 4-7 | | Civale, A | R | Civale, A | | Turnbull, S | R |
| 8/18/2021 | | @ | Oak | L | 0-5 | | Civale, A | R | Civale, A | | Fried, M | L |
| 8/20/2021 | | | Bos | L | 1-10 | | Bielak, B | R | Bielak, B | | Plutko, A | R |
| 8/20/2021 | | @ | LAA | L | 1-3 | | Bielak, B | R | Bielak, B | | Pineda, M | R |
| 8/21/2021 | | | Bos | L | 4-10 | | Castano, D | L | Castano, D | | Medina, A | R |
| 8/21/2021 | | @ | LAA | W | 4-2 | 14 | Castano, D | L | Weber, R | | Gomber, A | L |
| 8/22/2021 | | | Bos | L | 5-15 | | Shoemaker, M | R | Shoemaker, M | | Webb, L | R |
| 8/22/2021 | | @ | LAA | L | 0-1 | | Shoemaker, M | R | Shoemaker, M | | Darvish, Y | R |
| 8/23/2021 | | | NYY | L | 0-2 | | Houck, T | R | Houck, T | | Burnes, C | R |
| 8/23/2021 | | @ | Tex | W | 5-4 | | Houck, T | R | Houck, T | Perez, C | Thorpe, L | L |
| 8/24/2021 | | | NYY | L | 5-6 | 10 | Civale, A | R | Fry, J | | Lynn, L | R |
| 8/24/2021 | | @ | Tex | L | 3-6 | | Civale, A | R | Civale, A | | Sanchez, A | R |
| 8/25/2021 | | | NYY | L | 2-3 | | Bielak, B | R | Bielak, B | | May, D | R |
| 8/25/2021 | | @ | Tex | W | 5-2 | | Bielak, B | R | Weber, R | | Teheran, J | R |
| 8/27/2021 | | | TB | W | 8-5 | | Castano, D | L | McGowin, K | Fry, J | Garrett, B | L |
| 8/27/2021 | | @ | Sea | L | 4-9 | | Castano, D | L | Castano, D | | Skubal, T | L |
| 8/28/2021 | | | TB | L | 1-5 | | Shoemaker, M | R | Shoemaker, M | | Anderson, B | L |
| 8/28/2021 | | @ | Sea | L | 1-4 | | Shoemaker, M | R | Shoemaker, M | | Fedde, E | R |
| 8/29/2021 | | | TB | W | 4-3 | | Civale, A | R | Civale, A | Fry, J | Miller, T | R |
| 8/29/2021 | | @ | Sea | L | 1-6 | | Civale, A | R | Civale, A | | Minor, M | L |
| 9/13/2021 | | | Det | L | 5-8 | | Sanchez, S | R | Hembree, H | | Martinez, C | R |
| 9/13/2021 | | @ | Min | W | 3-2 | | Sanchez, S | R | Sanchez, S | | Nola, A | R |
| 9/14/2021 | | | Det | L | 2-9 | | Suarez, J | L | Suarez, J | | Lester, J | L |
| 9/14/2021 | | @ | Min | L | 3-5 | | Suarez, J | L | Bielak, B | | Allard, K | L |
| 9/15/2021 | | | Det | L | 3-8 | | Castano, D | L | Bacus, D | | Bauer, T | R |
| 9/15/2021 | | @ | Min | L | 7-9 | | Weber, R | R | Weber, R | | Musgrove, J | R |
| 9/17/2021 | | @ | ChW | L | 3-6 | | Houck, T | R | Doolittle, S | | Antone, T | R |
| 9/17/2021 | | | KC | L | 4-5 | | Oswalt, C | R | Oswalt, C | | Arrieta, J | R |
| 9/18/2021 | | @ | ChW | W | 4-3 | | Sanchez, S | R | Sanchez, S | Fry, J | Freeland, K | L |
| 9/18/2021 | | | KC | L | 2-3 | | Sanchez, S | R | Hembree, H | | Lamet, D | R |
| 9/19/2021 | | @ | ChW | L | 10-21 | | Suarez, J | L | Suarez, J | | Tanaka, M | R |
| 9/19/2021 | | | KC | L | 5-14 | | Suarez, J | L | Suarez, J | | Voth, A | R |
| 9/20/2021 | | | ChW | L | 2-4 | 10 | Castano, D | L | Hembree, H | | Freeland, K | L |
| 9/20/2021 | | @ | KC | L | 4-11 | | Weber, R | R | Weber, R | | Singer, B | R |
| 9/21/2021 | | | ChW | L | 4-11 | | Weber, R | R | Doolittle, S | | Weaver, L | R |
| 9/21/2021 | | @ | KC | L | 1-5 | | Oswalt, C | R | Oswalt, C | | Lindblom, J | R |
| 9/22/2021 | | | ChW | L | 2-11 | | Sanchez, S | R | Sanchez, S | | Peralta, F | R |
| 9/22/2021 | | @ | KC | W | 4-3 | | Lockett, W | R | Lockett, W | Hembree, H | Lamet, D | R |
| 9/24/2021 | | | Min | L | 2-7 | | Oswalt, C | R | Oswalt, C | | Urena, J | R |
| 9/24/2021 | | @ | Det | L | 4-5 | | Sanchez, S | R | Bielak, B | | Cody, K | R |
| 9/25/2021 | | | Min | W | 6-1 | | Suarez, J | L | Suarez, J | | Musgrove, J | R |
| 9/25/2021 | | @ | Det | L | 0-14 | | Suarez, J | L | Suarez, J | | Marquez, G | R |
| 9/26/2021 | | | Min | L | 2-5 | | Weber, R | R | Weber, R | | Kremer, D | R |
| 9/26/2021 | | @ | Det | W | 7-5 | 10 | Oswalt, C | R | Weber, R | | Lester, J | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/15/2021 | | | Min | L | | 1 | 6 | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/15/2021 | | @ | Det | L | | 2 | 4 | 0 | 2 | .000 | 0-2 | L2 | 2 |
| 4/16/2021 | | | Min | W | Bichette, B | 3 | 0 | 1 | 2 | .333 | 1-2 | W1 | 3 |
| 4/16/2021 | | @ | Det | W | Olivares, E | 5 | 2 | 2 | 2 | .500 | 2-2 | W2 | 4 |
| 4/17/2021 | | | Min | L | | 4 | 7 | 2 | 3 | .400 | 2-3 | L1 | 5 |
| 4/17/2021 | | @ | Det | W | Jansen, D | 1 | 0 | 3 | 3 | .500 | 3-3 | W1 | 6 |
| 4/19/2021 | | | ChW | W | Lewis, K | 6 | 3 | 4 | 3 | .571 | 4-3 | W2 | 7 |
| 4/19/2021 | | @ | KC | W | Jansen, D | 9 | 1 | 5 | 3 | .625 | 5-3 | W3 | 8 |
| 4/20/2021 | | | ChW | W | Mercer, J | 6 | 5 | 6 | 3 | .667 | 6-3 | W4 | 9 |
| 4/20/2021 | | @ | KC | L | | 0 | 2 | 6 | 4 | .600 | 6-4 | L1 | 10 |
| 4/21/2021 | | | ChW | L | | 6 | 8 | 6 | 5 | .545 | 6-4 | L2 | 11 |
| 4/21/2021 | | @ | KC | L | | 9 | 10 | 6 | 6 | .500 | 6-4 | L3 | 12 |
| 4/22/2021 | | @ | ChW | L | | 1 | 4 | 6 | 7 | .462 | 5-5 | L4 | 13 |
| 4/22/2021 | | | KC | W | Lewis, K | 8 | 7 | 7 | 7 | .500 | 5-5 | W1 | 14 |
| 4/23/2021 | | @ | ChW | L | | 6 | 7 | 7 | 8 | .467 | 5-5 | L1 | 15 |
| 4/23/2021 | | | KC | W | Bichette, B | 16 | 7 | 8 | 8 | .500 | 5-5 | W1 | 16 |
| 4/24/2021 | | @ | ChW | L | | 2 | 4 | 8 | 9 | .471 | 4-6 | L1 | 17 |
| 4/24/2021 | | | KC | L | | 4 | 11 | 8 | 10 | .444 | 3-7 | L2 | 18 |
| 4/26/2021 | | | Det | L | | 2 | 13 | 8 | 11 | .421 | 2-8 | L3 | 19 |
| 4/26/2021 | | @ | Min | W | Romine, A | 7 | 3 | 9 | 11 | .450 | 3-7 | W1 | 20 |
| 4/27/2021 | | | Det | L | | 0 | 5 | 9 | 12 | .429 | 3-7 | L1 | 21 |
| 4/27/2021 | | @ | Min | L | | 4 | 5 | 9 | 13 | .409 | 3-7 | L2 | 22 |
| 4/28/2021 | | | Det | W | Olivares, E | 7 | 3 | 10 | 13 | .435 | 4-6 | W1 | 23 |
| 4/28/2021 | | @ | Min | L | | 2 | 6 | 10 | 14 | .417 | 3-7 | L1 | 24 |
| 5/13/2021 | | | Atl | W | Lewis, K | 2 | 0 | 11 | 14 | .440 | 4-6 | W1 | 25 |
| 5/13/2021 | | @ | Col | L | | 1 | 5 | 11 | 15 | .423 | 3-7 | L1 | 26 |
| 5/14/2021 | | | Atl | L | | 2 | 6 | 11 | 16 | .407 | 3-7 | L2 | 27 |
| 5/14/2021 | | @ | Col | L | | 2 | 6 | 11 | 17 | .393 | 3-7 | L3 | 28 |
| 5/15/2021 | | | Atl | W | Romine, A | 8 | 1 | 12 | 17 | .414 | 4-6 | W1 | 29 |
| 5/15/2021 | | @ | Col | L | | 4 | 6 | 12 | 18 | .400 | 3-7 | L1 | 30 |
| 5/17/2021 | | @ | LAD | L | | 2 | 7 | 12 | 19 | .387 | 3-7 | L2 | 31 |
| 5/17/2021 | | | Phi | L | | 3 | 7 | 12 | 20 | .375 | 3-7 | L3 | 32 |
| 5/18/2021 | | @ | LAD | W | Jansen, D | 4 | 3 | 13 | 20 | .394 | 3-7 | W1 | 33 |
| 5/18/2021 | | | Phi | L | | 0 | 2 | 13 | 21 | .382 | 3-7 | L1 | 34 |
| 5/19/2021 | | @ | LAD | L | | 3 | 7 | 13 | 22 | .371 | 2-8 | L2 | 35 |
| 5/19/2021 | | | Phi | W | Gordon, A | 5 | 2 | 14 | 22 | .389 | 3-7 | W1 | 36 |
| 5/21/2021 | | @ | SF | W | Seager, K | 5 | 0 | 15 | 22 | .405 | 4-6 | W2 | 37 |
| 5/21/2021 | | | NYM | W | Hoskins, R | 14 | 3 | 16 | 22 | .421 | 5-5 | W3 | 38 |
| 5/22/2021 | | @ | SF | W | Romine, A | 2 | 0 | 17 | 22 | .436 | 5-5 | W4 | 39 |
| 5/22/2021 | | | NYM | W | Arauz, J | 2 | 1 | 18 | 22 | .450 | 6-4 | W5 | 40 |
| 5/23/2021 | | @ | SF | W | Jansen, D | 4 | 1 | 19 | 22 | .463 | 7-3 | W6 | 41 |
| 5/23/2021 | | | NYM | W | Lewis, K | 9 | 6 | 20 | 22 | .476 | 8-2 | W7 | 42 |
| 5/24/2021 | | @ | SD | L | | 5 | 19 | 20 | 23 | .465 | 7-3 | L1 | 43 |
| 5/24/2021 | | | Mia | L | | 1 | 7 | 20 | 24 | .455 | 7-3 | L2 | 44 |
| 5/25/2021 | | @ | SD | L | | 3 | 5 | 20 | 25 | .444 | 7-3 | L3 | 45 |
| 5/25/2021 | | | Mia | L | | 1 | 6 | 20 | 26 | .435 | 6-4 | L4 | 46 |
| 5/26/2021 | | @ | SD | L | | 1 | 15 | 20 | 27 | .426 | 5-5 | L5 | 47 |
| 5/26/2021 | | | Mia | L | | 1 | 5 | 20 | 28 | .417 | 4-6 | L6 | 48 |
| 5/28/2021 | | | Was | L | | 8 | 14 | 20 | 29 | .408 | 3-7 | L7 | 49 |
| 5/28/2021 | | @ | Ari | W | Seager, K | 3 | 2 | 21 | 29 | .420 | 3-7 | W1 | 50 |
| 5/29/2021 | | | Was | L | | 2 | 3 | 21 | 30 | .412 | 2-8 | L1 | 51 |
| 5/29/2021 | | @ | Ari | W | Lewis, K | 4 | 3 | 22 | 30 | .423 | 2-8 | W1 | 52 |
| 5/30/2021 | | | Was | W | Arauz, J | 9 | 8 | 23 | 30 | .434 | 3-7 | W2 | 53 |
| 5/30/2021 | | @ | Ari | L | | 7 | 8 | 23 | 31 | .426 | 3-7 | L1 | 54 |
| 6/14/2021 | | | LAA | L | | 3 | 4 | 23 | 32 | .418 | 3-7 | L2 | 55 |
| 6/14/2021 | | @ | Tor | W | Hoskins, R | 10 | 3 | 24 | 32 | .429 | 4-6 | W1 | 56 |
| 6/15/2021 | | | LAA | W | Lewis, K | 2 | 0 | 25 | 32 | .439 | 5-5 | W2 | 57 |
| 6/15/2021 | | @ | Tor | L | | 3 | 4 | 25 | 33 | .431 | 5-5 | L1 | 58 |
| 6/16/2021 | | | LAA | L | | 5 | 9 | 25 | 34 | .424 | 5-5 | L2 | 59 |
| 6/16/2021 | | @ | Tor | L | | 2 | 9 | 25 | 35 | .417 | 4-6 | L3 | 60 |
| 6/17/2021 | | @ | Bos | L | | 3 | 4 | 25 | 36 | .410 | 4-6 | L4 | 61 |
| 6/17/2021 | | | Tex | W | Jansen, D | 6 | 3 | 26 | 36 | .419 | 4-6 | W1 | 62 |
| 6/18/2021 | | @ | Bos | L | | 3 | 5 | 26 | 37 | .413 | 3-7 | L1 | 63 |
| 6/18/2021 | | | Tex | W | Schrock, M | 7 | 2 | 27 | 37 | .422 | 4-6 | W1 | 64 |
| 6/19/2021 | | @ | Bos | L | | 4 | 8 | 27 | 38 | .415 | 4-6 | L1 | 65 |
| 6/19/2021 | | | Tex | W | Gordon, A | 14 | 4 | 28 | 38 | .424 | 4-6 | W1 | 66 |
| 6/21/2021 | | | Hou | W | Seager, K | 5 | 1 | 29 | 38 | .433 | 4-6 | W2 | 67 |
| 6/21/2021 | | @ | NYY | L | | 0 | 1 | 29 | 39 | .426 | 4-6 | L1 | 68 |
| 6/22/2021 | | | Hou | W | Hoskins, R | 6 | 0 | 30 | 39 | .435 | 5-5 | W1 | 69 |
| 6/22/2021 | | @ | NYY | L | | 8 | 10 | 30 | 40 | .429 | 5-5 | L1 | 70 |
| 6/23/2021 | | | Hou | W | Seager, K | 11 | 4 | 31 | 40 | .437 | 6-4 | W1 | 71 |
| 6/23/2021 | | @ | NYY | L | | 1 | 2 | 31 | 41 | .431 | 5-5 | L1 | 72 |
| 6/24/2021 | | @ | Bal | L | | 2 | 5 | 31 | 42 | .425 | 5-5 | L2 | 73 |
| 6/24/2021 | | | Sea | L | | 4 | 6 | 31 | 43 | .419 | 4-6 | L3 | 74 |
| 6/25/2021 | | @ | Bal | L | | 3 | 4 | 31 | 44 | .413 | 4-6 | L4 | 75 |
| 6/25/2021 | | | Sea | L | | 2 | 3 | 31 | 45 | .408 | 3-7 | L5 | 76 |
| 6/26/2021 | | @ | Bal | L | | 3 | 6 | 31 | 46 | .403 | 2-8 | L6 | 77 |
| 6/26/2021 | | | Sea | L | | 0 | 2 | 31 | 47 | .397 | 2-8 | L7 | 78 |
| 6/28/2021 | | | Oak | L | | 4 | 7 | 31 | 48 | .392 | 1-9 | L8 | 79 |
| 6/28/2021 | | @ | TB | W | Smoak, J | 6 | 2 | 32 | 48 | .400 | 2-8 | W1 | 80 |
| 6/29/2021 | | | Oak | W | Seager, K | 7 | 4 | 33 | 48 | .407 | 2-8 | W2 | 81 |
| 6/29/2021 | | @ | TB | W | Gordon, A | 9 | 4 | 34 | 48 | .415 | 3-7 | W3 | 82 |
| 6/30/2021 | | | Oak | L | | 6 | 9 | 34 | 49 | .410 | 3-7 | L1 | 83 |
| 6/30/2021 | | @ | TB | L | | 5 | 7 | 34 | 50 | .405 | 3-7 | L2 | 84 |
| 7/15/2021 | | | ChW | L | | 2 | 13 | 34 | 51 | .400 | 3-7 | L3 | 85 |
| 7/15/2021 | | @ | KC | L | | 2 | 8 | 34 | 52 | .395 | 3-7 | L4 | 86 |
| 7/16/2021 | | | ChW | L | | 3 | 5 | 34 | 53 | .391 | 3-7 | L5 | 87 |
| 7/16/2021 | | @ | KC | L | | 2 | 15 | 34 | 54 | .386 | 3-7 | L6 | 88 |
| 7/17/2021 | | | ChW | L | | 7 | 9 | 34 | 55 | .382 | 3-7 | L7 | 89 |
| 7/17/2021 | | @ | KC | L | | 0 | 3 | 34 | 56 | .378 | 2-8 | L8 | 90 |
| 7/19/2021 | | | Det | W | Lewis, K | 7 | 4 | 35 | 56 | .385 | 2-8 | W1 | 91 |
| 7/19/2021 | | @ | Min | L | | 0 | 16 | 35 | 57 | .380 | 1-9 | L1 | 92 |
| 7/20/2021 | | | Det | L | | 0 | 9 | 35 | 58 | .376 | 1-9 | L2 | 93 |
| 7/20/2021 | | @ | Min | L | | 3 | 5 | 35 | 59 | .372 | 1-9 | L3 | 94 |
| 7/21/2021 | | | Det | L | | 3 | 9 | 35 | 60 | .368 | 1-9 | L4 | 95 |
| 7/21/2021 | | @ | Min | L | | 4 | 14 | 35 | 61 | .365 | 1-9 | L5 | 96 |
| 7/22/2021 | | | Min | L | | 9 | 15 | 35 | 62 | .361 | 1-9 | L6 | 97 |
| 7/22/2021 | | @ | Det | L | | 0 | 8 | 35 | 63 | .357 | 1-9 | L7 | 98 |
| 7/23/2021 | | | Min | L | | 2 | 3 | 35 | 64 | .354 | 1-9 | L8 | 99 |
| 7/23/2021 | | @ | Det | L | | 1 | 3 | 35 | 65 | .350 | 1-9 | L9 | 100 |
| 7/24/2021 | | | Min | L | | 3 | 6 | 35 | 66 | .347 | 0-10 | L10 | 101 |
| 7/24/2021 | | @ | Det | L | | 2 | 7 | 35 | 67 | .343 | 0-10 | L11 | 102 |
| 7/26/2021 | | @ | ChW | L | | 3 | 7 | 35 | 68 | .340 | 0-10 | L12 | 103 |
| 7/26/2021 | | | KC | W | Arauz, J | 6 | 5 | 36 | 68 | .346 | 1-9 | W1 | 104 |
| 7/27/2021 | | @ | ChW | L | | 6 | 7 | 36 | 69 | .343 | 1-9 | L1 | 105 |
| 7/27/2021 | | | KC | L | | 12 | 17 | 36 | 70 | .340 | 1-9 | L2 | 106 |
| 7/28/2021 | | @ | ChW | L | | 7 | 9 | 36 | 71 | .336 | 1-9 | L3 | 107 |
| 7/28/2021 | | | KC | W | Gordon, A | 9 | 6 | 37 | 71 | .343 | 2-8 | W1 | 108 |
| 8/13/2021 | | @ | Hou | L | | 1 | 3 | 37 | 72 | .339 | 2-8 | L1 | 109 |
| 8/13/2021 | | | Tor | L | | 3 | 13 | 37 | 73 | .336 | 2-8 | L2 | 110 |
| 8/14/2021 | | @ | Hou | L | | 4 | 5 | 37 | 74 | .333 | 2-8 | L3 | 111 |
| 8/14/2021 | | | Tor | L | | 5 | 9 | 37 | 75 | .330 | 2-8 | L4 | 112 |
| 8/15/2021 | | @ | Hou | L | | 0 | 5 | 37 | 76 | .327 | 2-8 | L5 | 113 |
| 8/15/2021 | | | Tor | L | | 5 | 17 | 37 | 77 | .325 | 1-9 | L6 | 114 |
| 8/16/2021 | | | Bal | L | | 3 | 14 | 37 | 78 | .322 | 1-9 | L7 | 115 |
| 8/16/2021 | | @ | Oak | L | | 0 | 8 | 37 | 79 | .319 | 1-9 | L8 | 116 |
| 8/17/2021 | | | Bal | L | | 1 | 3 | 37 | 80 | .316 | 1-9 | L9 | 117 |
| 8/17/2021 | | @ | Oak | L | | 0 | 1 | 37 | 81 | .314 | 0-10 | L10 | 118 |
| 8/18/2021 | | | Bal | L | | 4 | 7 | 37 | 82 | .311 | 0-10 | L11 | 119 |
| 8/18/2021 | | @ | Oak | L | | 0 | 5 | 37 | 83 | .308 | 0-10 | L12 | 120 |
| 8/20/2021 | | | Bos | L | | 1 | 10 | 37 | 84 | .306 | 0-10 | L13 | 121 |
| 8/20/2021 | | @ | LAA | L | | 1 | 3 | 37 | 85 | .303 | 0-10 | L14 | 122 |
| 8/21/2021 | | | Bos | L | | 4 | 10 | 37 | 86 | .301 | 0-10 | L15 | 123 |
| 8/21/2021 | | @ | LAA | W | Hoskins, R | 4 | 2 | 38 | 86 | .306 | 1-9 | W1 | 124 |
| 8/22/2021 | | | Bos | L | | 5 | 15 | 38 | 87 | .304 | 1-9 | L1 | 125 |
| 8/22/2021 | | @ | LAA | L | | 0 | 1 | 38 | 88 | .302 | 1-9 | L2 | 126 |
| 8/23/2021 | | | NYY | L | | 0 | 2 | 38 | 89 | .299 | 1-9 | L3 | 127 |
| 8/23/2021 | | @ | Tex | W | Lewis, K | 5 | 4 | 39 | 89 | .305 | 2-8 | W1 | 128 |
| 8/24/2021 | | | NYY | L | | 5 | 6 | 39 | 90 | .302 | 2-8 | L1 | 129 |
| 8/24/2021 | | @ | Tex | L | | 3 | 6 | 39 | 91 | .300 | 2-8 | L2 | 130 |
| 8/25/2021 | | | NYY | L | | 2 | 3 | 39 | 92 | .298 | 2-8 | L3 | 131 |
| 8/25/2021 | | @ | Tex | W | Dyson, J | 5 | 2 | 40 | 92 | .303 | 3-7 | W1 | 132 |
| 8/27/2021 | | | TB | W | Arauz, J | 8 | 5 | 41 | 92 | .308 | 4-6 | W2 | 133 |
| 8/27/2021 | | @ | Sea | L | | 4 | 9 | 41 | 93 | .306 | 3-7 | L1 | 134 |
| 8/28/2021 | | | TB | L | | 1 | 5 | 41 | 94 | .304 | 3-7 | L2 | 135 |
| 8/28/2021 | | @ | Sea | L | | 1 | 4 | 41 | 95 | .301 | 3-7 | L3 | 136 |
| 8/29/2021 | | | TB | W | Hoskins, R | 4 | 3 | 42 | 95 | .307 | 4-6 | W1 | 137 |
| 8/29/2021 | | @ | Sea | L | | 1 | 6 | 42 | 96 | .304 | 3-7 | L1 | 138 |
| 9/13/2021 | | | Det | L | | 5 | 8 | 42 | 97 | .302 | 3-7 | L2 | 139 |
| 9/13/2021 | | @ | Min | W | Jansen, D | 3 | 2 | 43 | 97 | .307 | 4-6 | W1 | 140 |
| 9/14/2021 | | | Det | L | | 2 | 9 | 43 | 98 | .305 | 4-6 | L1 | 141 |
| 9/14/2021 | | @ | Min | L | | 3 | 5 | 43 | 99 | .303 | 3-7 | L2 | 142 |
| 9/15/2021 | | | Det | L | | 3 | 8 | 43 | 100 | .301 | 2-8 | L3 | 143 |
| 9/15/2021 | | @ | Min | L | | 7 | 9 | 43 | 101 | .299 | 2-8 | L4 | 144 |
| 9/17/2021 | | @ | ChW | L | | 3 | 6 | 43 | 102 | .297 | 2-8 | L5 | 145 |
| 9/17/2021 | | | KC | L | | 4 | 5 | 43 | 103 | .295 | 2-8 | L6 | 146 |
| 9/18/2021 | | @ | ChW | W | Olivares, E | 4 | 3 | 44 | 103 | .299 | 2-8 | W1 | 147 |
| 9/18/2021 | | | KC | L | | 2 | 3 | 44 | 104 | .297 | 2-8 | L1 | 148 |
| 9/19/2021 | | @ | ChW | L | | 10 | 21 | 44 | 105 | .295 | 2-8 | L2 | 149 |
| 9/19/2021 | | | KC | L | | 5 | 14 | 44 | 106 | .293 | 1-9 | L3 | 150 |
| 9/20/2021 | | | ChW | L | | 2 | 4 | 44 | 107 | .291 | 1-9 | L4 | 151 |
| 9/20/2021 | | @ | KC | L | | 4 | 11 | 44 | 108 | .289 | 1-9 | L5 | 152 |
| 9/21/2021 | | | ChW | L | | 4 | 11 | 44 | 109 | .288 | 1-9 | L6 | 153 |
| 9/21/2021 | | @ | KC | L | | 1 | 5 | 44 | 110 | .286 | 1-9 | L7 | 154 |
| 9/22/2021 | | | ChW | L | | 2 | 11 | 44 | 111 | .284 | 1-9 | L8 | 155 |
| 9/22/2021 | | @ | KC | W | Lewis, K | 4 | 3 | 45 | 111 | .288 | 2-8 | W1 | 156 |
| 9/24/2021 | | | Min | L | | 2 | 7 | 45 | 112 | .287 | 1-9 | L1 | 157 |
| 9/24/2021 | | @ | Det | L | | 4 | 5 | 45 | 113 | .285 | 1-9 | L2 | 158 |
| 9/25/2021 | | | Min | W | Smoak, J | 6 | 1 | 46 | 113 | .289 | 2-8 | W1 | 159 |
| 9/25/2021 | | @ | Det | L | | 0 | 14 | 46 | 114 | .287 | 2-8 | L1 | 160 |
| 9/26/2021 | | | Min | L | | 2 | 5 | 46 | 115 | .286 | 2-8 | L2 | 161 |
| 9/26/2021 | | @ | Det | W | Hoskins, R | 7 | 5 | 47 | 115 | .290 | 3-7 | W1 | 162 |