Team game results - 2010 Chicago White Sox
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/7/2010 | | | Bal | W | 4-2 | | Blackburn, N | R | Blackburn, N | Nathan, J | Lohse, K | R |
| 4/7/2010 | | @ | Tam | W | 13-1 | | Sabathia, C | L | Sabathia, C | | Petit, Y | R |
| 4/8/2010 | | | Bal | L | 0-4 | | VandenHurk, R | R | VandenHurk, R | | Narveson, C | L |
| 4/8/2010 | | @ | Tam | W | 4-3 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Colon, B | R |
| 4/9/2010 | | @ | Bal | W | 8-4 | | VandenHurk, R | R | VandenHurk, R | | Pineiro, J | R |
| 4/9/2010 | | | Tam | W | 10-3 | | Sabathia, C | L | Sabathia, C | | Lerew, A | R |
| 4/10/2010 | | @ | Bal | L | 3-9 | | Latos, M | R | Latos, M | | Lohse, K | R |
| 4/10/2010 | | | Tam | W | 7-1 | | Bannister, B | R | Bannister, B | | Hill, S | R |
| 4/11/2010 | | @ | Bal | W | 6-4 | | Blackburn, N | R | Blackburn, N | Nathan, J | Kuroda, H | R |
| 4/11/2010 | | | Tam | W | 10-5 | | Gonzalez, G | L | Gonzalez, G | | Myers, B | R |
| 4/13/2010 | | | Tor | L | 2-3 | 11 | Blackburn, N | R | Betancourt, R | | Lincecum, T | R |
| 4/13/2010 | | @ | Oak | W | 7-6 | | Sabathia, C | L | Perez, C | Nathan, J | Garza, M | R |
| 4/14/2010 | | | Tor | W | 5-4 | | VandenHurk, R | R | Troncoso, R | | Verlander, J | R |
| 4/14/2010 | | @ | Oak | W | 12-2 | | Rowland-Smith, R | L | Rowland-Smith, R | | Duke, Z | L |
| 4/15/2010 | | | Tor | W | 2-1 | 10 | Sabathia, C | L | Nathan, J | | Anderson, B | L |
| 4/15/2010 | | @ | Oak | W | 9-1 | | VandenHurk, R | R | VandenHurk, R | | Chamberlain, J | R |
| 4/16/2010 | | | NYY | L | 2-3 | 11 | Bannister, B | R | Nathan, J | | Pavano, C | R |
| 4/16/2010 | | @ | Tex | L | 1-2 | | Latos, M | R | Latos, M | | Hanson, T | R |
| 4/17/2010 | | | NYY | L | 3-4 | | Blackburn, N | R | Ni, F | | Slowey, K | R |
| 4/17/2010 | | @ | Tex | L | 6-7 | | Blackburn, N | R | Blackburn, N | | Pettitte, A | L |
| 4/18/2010 | | | NYY | W | 6-4 | | VandenHurk, R | R | Seay, B | Betancourt, R | Johnson, J | R |
| 4/18/2010 | | @ | Tex | W | 3-1 | | Sabathia, C | L | Sabathia, C | | Suppan, J | R |
| 4/20/2010 | | | Tex | W | 6-2 | | Sabathia, C | L | Sabathia, C | | Suppan, J | R |
| 4/20/2010 | | @ | NYY | W | 11-4 | | Rowland-Smith, R | L | Perez, C | | Porcello, R | R |
| 4/21/2010 | | | Tex | W | 4-3 | | Bannister, B | R | Bannister, B | Nathan, J | Feldman, S | R |
| 4/21/2010 | | @ | NYY | L | 3-4 | | VandenHurk, R | R | VandenHurk, R | | Pavano, C | R |
| 4/22/2010 | | | Tex | W | 3-0 | | Blackburn, N | R | Blackburn, N | | Hanson, T | R |
| 4/22/2010 | | @ | NYY | L | 1-2 | | Latos, M | R | Latos, M | | Johnson, J | R |
| 5/13/2010 | | | Bos | L | 4-5 | 11 | Sabathia, C | L | Nathan, J | | Santana, E | R |
| 5/13/2010 | | @ | Sea | L | 0-7 | | Bannister, B | R | Bannister, B | | Mazzaro, V | R |
| 5/14/2010 | | | Bos | L | 2-4 | | Rowland-Smith, R | L | Rowland-Smith, R | | Wolf, R | L |
| 5/14/2010 | | @ | Sea | L | 3-4 | | Blackburn, N | R | Blackburn, N | | Medlen, K | R |
| 5/15/2010 | | | Bos | W | 1-0 | | Blackburn, N | R | Blackburn, N | Nathan, J | Bergesen, B | R |
| 5/15/2010 | | @ | Sea | L | 3-13 | | Sabathia, C | L | Sabathia, C | | Lester, J | L |
| 5/16/2010 | | | Bos | L | 3-7 | 13 | VandenHurk, R | R | Seay, B | | Sanchez, A | R |
| 5/16/2010 | | @ | Sea | W | 7-4 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Hammel, J | R |
| 5/17/2010 | | @ | LAA | W | 5-1 | | Latos, M | R | Latos, M | | Greinke, Z | R |
| 5/18/2010 | | @ | LAA | L | 4-12 | | Bannister, B | R | Bannister, B | | Haren, D | R |
| 5/19/2010 | | @ | LAA | L | 1-2 | | Blackburn, N | R | Blackburn, N | | Buehrle, M | L |
| 5/21/2010 | | | LAA | L | 4-7 | | Blackburn, N | R | Blackburn, N | | Buehrle, M | L |
| 5/22/2010 | | | LAA | W | 10-4 | | VandenHurk, R | R | VandenHurk, R | | Greinke, Z | R |
| 5/23/2010 | | | LAA | W | 8-4 | | Bannister, B | R | Bannister, B | | Maholm, P | L |
| 5/24/2010 | | @ | Bos | L | 0-4 | | Bannister, B | R | Bannister, B | | de la Rosa, J | L |
| 5/24/2010 | | | Sea | W | 12-2 | | Bannister, B | R | Bannister, B | | Mazzaro, V | R |
| 5/25/2010 | | @ | Bos | W | 5-0 | | Latos, M | R | Latos, M | Seay, B | Palmer, M | R |
| 5/25/2010 | | | Sea | W | 7-0 | | Sabathia, C | L | Sabathia, C | | Young, C | R |
| 5/26/2010 | | @ | Bos | L | 2-4 | | Blackburn, N | R | Blackburn, N | | Sanchez, A | R |
| 5/26/2010 | | | Sea | W | 4-3 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Vargas, J | L |
| 5/27/2010 | | | Cle | L | 4-5 | 10 | Blackburn, N | R | Betancourt, R | | Liriano, F | L |
| 5/27/2010 | | @ | Min | W | 2-0 | | Sabathia, C | L | Sabathia, C | Nathan, J | Carpenter, C | R |
| 5/28/2010 | | | Cle | W | 5-4 | | VandenHurk, R | R | VandenHurk, R | Nathan, J | Lee, C | L |
| 5/28/2010 | | @ | Min | L | 1-7 | | Rowland-Smith, R | L | Rowland-Smith, R | | Dempster, R | R |
| 5/29/2010 | | | Cle | W | 6-2 | | Bannister, B | R | Bannister, B | | Harang, A | R |
| 5/29/2010 | | @ | Min | L | 2-7 | | Bannister, B | R | Bannister, B | | Rodriguez, W | L |
| 6/14/2010 | | | Oak | W | 5-1 | | Lowe, D | R | Lowe, D | Nathan, J | Maloney, M | L |
| 6/14/2010 | | @ | Tor | L | 3-7 | | Lowe, D | R | Lowe, D | | Bedard, E | L |
| 6/15/2010 | | | Oak | W | 5-1 | | VandenHurk, R | R | VandenHurk, R | | Johnson, R | L |
| 6/15/2010 | | @ | Tor | W | 2-0 | | Hudson, D | R | Hudson, D | Nathan, J | Anderson, B | L |
| 6/16/2010 | | | Oak | W | 6-5 | | Latos, M | R | Nathan, J | | Garza, M | R |
| 6/16/2010 | | @ | Tor | W | 12-2 | | Sabathia, C | L | Sabathia, C | | Moehler, B | R |
| 6/18/2010 | | @ | Bal | L | 2-3 | 10 | Bannister, B | R | Perez, C | | Hernandez, F | R |
| 6/18/2010 | | | Tam | W | 9-2 | | Sabathia, C | L | Sabathia, C | | Myers, B | R |
| 6/19/2010 | | @ | Bal | L | 3-5 | | Blackburn, N | R | Blackburn, N | | Zimmermann, J | R |
| 6/19/2010 | | | Tam | W | 10-3 | | Rowland-Smith, R | L | Rowland-Smith, R | | Hochevar, L | R |
| 6/20/2010 | | @ | Bal | W | 3-2 | | Lowe, D | R | Lowe, D | Nathan, J | Pineiro, J | R |
| 6/20/2010 | | | Tam | W | 10-2 | | Lowe, D | R | Lowe, D | | Smoltz, J | R |
| 6/21/2010 | | @ | Bos | W | 6-2 | | Hudson, D | R | Gervacio, S | Nathan, J | Palmer, M | R |
| 6/21/2010 | | | Sea | L | 1-4 | | VandenHurk, R | R | VandenHurk, R | | Hammel, J | R |
| 6/22/2010 | | @ | Bos | L | 1-4 | | Sabathia, C | L | Sabathia, C | | de la Rosa, J | L |
| 6/22/2010 | | | Sea | W | 6-5 | 10 | Sabathia, C | L | Ni, F | | Meche, G | R |
| 6/23/2010 | | @ | Bos | W | 4-1 | | Bannister, B | R | Bannister, B | Nathan, J | Bergesen, B | R |
| 6/23/2010 | | | Sea | L | 8-9 | 11 | Rowland-Smith, R | L | Perez, C | | Young, C | R |
| 6/25/2010 | | | Det | W | 10-5 | | Lowe, D | R | Troncoso, R | | Buchholz, C | R |
| 6/25/2010 | | @ | KC | L | 3-6 | | Blackburn, N | R | Blackburn, N | | Figueroa, N | R |
| 6/26/2010 | | | Det | W | 6-3 | | VandenHurk, R | R | VandenHurk, R | Nathan, J | Zambrano, C | R |
| 6/26/2010 | | @ | KC | W | 8-3 | | Lowe, D | R | Lowe, D | | Harrison, M | L |
| 6/27/2010 | | | Det | W | 5-2 | | Sabathia, C | L | Sabathia, C | Seay, B | Tallet, B | L |
| 6/27/2010 | | @ | KC | L | 3-4 | | Hudson, D | R | Gervacio, S | | Correia, K | R |
| 6/28/2010 | | | Det | W | 7-4 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Martis, S | R |
| 6/28/2010 | | @ | KC | W | 2-0 | 10 | Sabathia, C | L | Nathan, J | | Cueto, J | R |
| 7/12/2010 | | | Min | L | 1-6 | | Blackburn, N | R | Blackburn, N | | Guthrie, J | R |
| 7/12/2010 | | @ | Cle | L | 1-8 | | Blackburn, N | R | Blackburn, N | | Looper, B | R |
| 7/13/2010 | | | Min | L | 1-2 | | Sabathia, C | L | Sabathia, C | | Rodriguez, W | L |
| 7/13/2010 | | @ | Cle | W | 6-0 | | Bannister, B | R | Bannister, B | | Vazquez, J | R |
| 7/14/2010 | | | Min | L | 1-2 | | Rowland-Smith, R | L | Rowland-Smith, R | | Carpenter, C | R |
| 7/14/2010 | | @ | Cle | W | 12-4 | | Latos, M | R | Latos, M | | Liriano, F | L |
| 7/16/2010 | | | KC | W | 12-1 | | Lowe, D | R | Lowe, D | | Martin, J | R |
| 7/16/2010 | | @ | Det | W | 4-2 | | Sabathia, C | L | Nathan, J | | Garcia, F | R |
| 7/17/2010 | | | KC | W | 8-3 | | Bannister, B | R | Bannister, B | | Correia, K | R |
| 7/17/2010 | | @ | Det | W | 3-2 | | Lowe, D | R | Lowe, D | Wagner, B | Zambrano, C | R |
| 7/18/2010 | | | KC | W | 13-6 | | Blackburn, N | R | Blackburn, N | | Cueto, J | R |
| 7/18/2010 | | @ | Det | W | 13-2 | | Blackburn, N | R | Blackburn, N | | Tallet, B | L |
| 7/19/2010 | | | NYY | W | 4-1 | | Sabathia, C | L | Sabathia, C | Nathan, J | Porcello, R | R |
| 7/19/2010 | | @ | Tex | W | 9-7 | | Bannister, B | R | Bannister, B | Nathan, J | Feldman, S | R |
| 7/20/2010 | | | NYY | W | 5-3 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Slowey, K | R |
| 7/20/2010 | | @ | Tex | W | 9-1 | | Latos, M | R | Latos, M | | Detwiler, R | L |
| 7/21/2010 | | | NYY | W | 5-4 | | Bannister, B | R | Betancourt, R | | Johnson, J | R |
| 7/21/2010 | | @ | Tex | L | 6-7 | | Sabathia, C | L | Nathan, J | | Pettitte, A | L |
| 7/23/2010 | | | Tex | L | 4-7 | | Blackburn, N | R | Blackburn, N | | Buckner, B | R |
| 7/23/2010 | | @ | NYY | W | 9-2 | | Lowe, D | R | Lowe, D | | Porcello, R | R |
| 7/24/2010 | | | Tex | W | 12-2 | | Sabathia, C | L | Sabathia, C | | Pettitte, A | L |
| 7/24/2010 | | @ | NYY | L | 1-5 | | Blackburn, N | R | Blackburn, N | | Johnson, J | R |
| 7/25/2010 | | | Tex | W | 10-5 | | Rowland-Smith, R | L | Rowland-Smith, R | | Suppan, J | R |
| 7/25/2010 | | @ | NYY | W | 6-3 | | Bannister, B | R | Bannister, B | Nathan, J | Pavano, C | R |
| 7/27/2010 | | | Bos | W | 3-1 | | Bannister, B | R | Bannister, B | Nathan, J | Wolf, R | L |
| 7/27/2010 | | @ | Sea | L | 7-10 | | Latos, M | R | Perez, C | | Lester, J | L |
| 7/28/2010 | | | Bos | L | 4-5 | | Blackburn, N | R | Blackburn, N | | Sanchez, A | R |
| 7/28/2010 | | @ | Sea | L | 4-6 | 13 | Sabathia, C | L | Perez, C | | Hammel, J | R |
| 8/12/2010 | | | Bal | L | 0-5 | | Bannister, B | R | Bannister, B | | Hernandez, F | R |
| 8/12/2010 | | @ | Tam | W | 12-8 | | Blackburn, N | R | Blackburn, N | Nathan, J | Hochevar, L | R |
| 8/13/2010 | | | Bal | W | 3-0 | | Latos, M | R | Latos, M | Nathan, J | Kuroda, H | R |
| 8/13/2010 | | @ | Tam | W | 4-3 | | Bannister, B | R | Bannister, B | Nathan, J | DiNardo, L | L |
| 8/14/2010 | | | Bal | W | 7-1 | | Blackburn, N | R | Blackburn, N | | Pineiro, J | R |
| 8/14/2010 | | @ | Tam | W | 4-1 | | Sabathia, C | L | Sabathia, C | Wagner, B | Petit, Y | R |
| 8/15/2010 | | | Bal | L | 5-6 | | Sabathia, C | L | Nathan, J | | Nieve, F | R |
| 8/15/2010 | | @ | Tam | L | 3-6 | | Rowland-Smith, R | L | Rowland-Smith, R | | Colon, B | R |
| 8/16/2010 | | @ | LAA | L | 3-4 | 10 | VandenHurk, R | R | Perez, C | | Greinke, Z | R |
| 8/17/2010 | | @ | LAA | W | 6-5 | | Blackburn, N | R | Blackburn, N | Nathan, J | Haren, D | R |
| 8/18/2010 | | @ | LAA | W | 4-2 | | Bannister, B | R | Bannister, B | Nathan, J | Buehrle, M | L |
| 8/20/2010 | | | LAA | W | 5-2 | | Lowe, D | R | Ni, F | Nathan, J | Buehrle, M | L |
| 8/21/2010 | | | LAA | W | 1-0 | | Bannister, B | R | Bannister, B | | Greinke, Z | R |
| 8/22/2010 | | | LAA | W | 4-2 | | Blackburn, N | R | Blackburn, N | Nathan, J | Maholm, P | L |
| 8/23/2010 | | | Oak | W | 4-1 | | Sabathia, C | L | Sabathia, C | Nathan, J | Chamberlain, J | R |
| 8/23/2010 | | @ | Tor | W | 5-1 | | Sabathia, C | L | Troncoso, R | | Lincecum, T | R |
| 8/24/2010 | | | Oak | L | 1-2 | | Lowe, D | R | Nathan, J | | Maine, J | R |
| 8/24/2010 | | @ | Tor | W | 6-4 | | VandenHurk, R | R | VandenHurk, R | Nathan, J | Bedard, E | L |
| 8/25/2010 | | | Oak | L | 3-4 | | Bannister, B | R | Bannister, B | | Duke, Z | L |
| 8/25/2010 | | @ | Tor | W | 5-4 | | Bannister, B | R | Bannister, B | Nathan, J | Anderson, B | L |
| 8/27/2010 | | | Cle | W | 10-5 | | Blackburn, N | R | Blackburn, N | | Looper, B | R |
| 8/27/2010 | | @ | Min | W | 3-2 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Contreras, J | R |
| 8/28/2010 | | | Cle | W | 7-6 | | Sabathia, C | L | Ni, F | | Harang, A | R |
| 8/28/2010 | | @ | Min | W | 4-3 | | Blackburn, N | R | Betancourt, R | Nathan, J | Rodriguez, W | L |
| 8/29/2010 | | | Cle | L | 4-7 | | Lowe, D | R | Lowe, D | | Lee, C | L |
| 8/29/2010 | | @ | Min | L | 0-1 | | Sabathia, C | L | Sabathia, C | | Carpenter, C | R |
| 9/12/2010 | | | Tor | W | 6-1 | | Lowe, D | R | Lowe, D | | Moehler, B | R |
| 9/12/2010 | | @ | Oak | L | 2-6 | | Latos, M | R | Latos, M | | Ray, R | R |
| 9/13/2010 | | | Tor | W | 4-3 | | Rowland-Smith, R | L | Ni, F | | Anderson, B | L |
| 9/13/2010 | | @ | Oak | W | 6-2 | 10 | Sabathia, C | L | Nathan, J | | Maine, J | R |
| 9/14/2010 | | | Tor | W | 6-5 | | Blackburn, N | R | Ni, F | Nathan, J | Verlander, J | R |
| 9/14/2010 | | @ | Oak | W | 7-3 | | Rowland-Smith, R | L | Rowland-Smith, R | | Johnson, R | L |
| 9/15/2010 | | | Det | W | 3-2 | 10 | Blackburn, N | R | Nathan, J | | Wakefield, T | R |
| 9/15/2010 | | @ | KC | L | 2-8 | | Bannister, B | R | Bannister, B | | Correia, K | R |
| 9/16/2010 | | | Det | L | 2-5 | | Sabathia, C | L | Sabathia, C | | Martis, S | R |
| 9/16/2010 | | @ | KC | W | 4-3 | | Lowe, D | R | Lowe, D | Wagner, B | Cueto, J | R |
| 9/17/2010 | | | Det | W | 4-0 | | Bannister, B | R | Bannister, B | | Garcia, F | R |
| 9/17/2010 | | @ | KC | W | 12-1 | | Latos, M | R | Latos, M | | Romero, R | L |
| 9/18/2010 | | | KC | W | 8-6 | | Blackburn, N | R | Betancourt, R | Nathan, J | Correia, K | R |
| 9/18/2010 | | @ | Det | L | 1-3 | | Sabathia, C | L | Betancourt, R | | Wakefield, T | R |
| 9/19/2010 | | | KC | W | 10-5 | | Sabathia, C | L | Sabathia, C | | Cueto, J | R |
| 9/19/2010 | | @ | Det | W | 4-2 | | Rowland-Smith, R | L | Rowland-Smith, R | Nathan, J | Zambrano, C | R |
| 9/20/2010 | | | KC | L | 3-7 | | Bannister, B | R | Bannister, B | | Romero, R | L |
| 9/20/2010 | | @ | Det | L | 1-3 | | Blackburn, N | R | Blackburn, N | | Huff, D | L |
| 9/21/2010 | | | KC | W | 10-3 | | Lowe, D | R | Lowe, D | | Moyer, J | L |
| 9/21/2010 | | @ | Det | W | 8-3 | | Bannister, B | R | Bannister, B | Hudson, D | Tallet, B | L |
| 9/23/2010 | | | Min | W | 6-5 | | Blackburn, N | R | Ni, F | | Carpenter, C | R |
| 9/23/2010 | | @ | Cle | L | 0-1 | | Latos, M | R | Latos, M | | Lee, C | L |
| 9/24/2010 | | | Min | W | 2-1 | | Sabathia, C | L | Sabathia, C | Nathan, J | Guthrie, J | R |
| 9/24/2010 | | @ | Cle | W | 7-1 | | Sabathia, C | L | Sabathia, C | | Looper, B | R |
| 9/25/2010 | | | Min | W | 6-1 | | Bannister, B | R | Bannister, B | | Hudson, T | R |
| 9/25/2010 | | @ | Cle | W | 4-1 | | Gonzalez, G | L | Smith, J | Perez, C | Vazquez, J | R |
| 9/26/2010 | | | Min | W | 6-5 | | Lowe, D | R | Lowe, D | Nathan, J | Dempster, R | R |
| 9/26/2010 | | @ | Cle | W | 15-1 | | Blackburn, N | R | Blackburn, N | | Liriano, F | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/7/2010 | | | Bal | W | Lopez, F | 4 | 2 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/7/2010 | | @ | Tam | W | Zobrist, B | 13 | 1 | 2 | 0 | 1.000 | 2-0 | W2 | 2 |
| 4/8/2010 | | | Bal | L | | 0 | 4 | 2 | 1 | .667 | 2-1 | L1 | 3 |
| 4/8/2010 | | @ | Tam | W | Gross, G | 4 | 3 | 3 | 1 | .750 | 3-1 | W1 | 4 |
| 4/9/2010 | | @ | Bal | W | Chavez, E | 8 | 4 | 4 | 1 | .800 | 4-1 | W2 | 5 |
| 4/9/2010 | | | Tam | W | Beltran, C | 10 | 3 | 5 | 1 | .833 | 5-1 | W3 | 6 |
| 4/10/2010 | | @ | Bal | L | | 3 | 9 | 5 | 2 | .714 | 5-2 | L1 | 7 |
| 4/10/2010 | | | Tam | W | Inge, B | 7 | 1 | 6 | 2 | .750 | 6-2 | W1 | 8 |
| 4/11/2010 | | @ | Bal | W | Zobrist, B | 6 | 4 | 7 | 2 | .778 | 7-2 | W2 | 9 |
| 4/11/2010 | | | Tam | W | Lopez, F | 10 | 5 | 8 | 2 | .800 | 8-2 | W3 | 10 |
| 4/13/2010 | | | Tor | L | | 2 | 3 | 8 | 3 | .727 | 7-3 | L1 | 11 |
| 4/13/2010 | | @ | Oak | W | Youkilis, K | 7 | 6 | 9 | 3 | .750 | 7-3 | W1 | 12 |
| 4/14/2010 | | | Tor | W | Lopez, F | 5 | 4 | 10 | 3 | .769 | 8-2 | W2 | 13 |
| 4/14/2010 | | @ | Oak | W | Zobrist, B | 12 | 2 | 11 | 3 | .786 | 8-2 | W3 | 14 |
| 4/15/2010 | | | Tor | W | Lopez, F | 2 | 1 | 12 | 3 | .800 | 8-2 | W4 | 15 |
| 4/15/2010 | | @ | Oak | W | Gomez, C | 9 | 1 | 13 | 3 | .813 | 8-2 | W5 | 16 |
| 4/16/2010 | | | NYY | L | | 2 | 3 | 13 | 4 | .765 | 8-2 | L1 | 17 |
| 4/16/2010 | | @ | Tex | L | | 1 | 2 | 13 | 5 | .722 | 7-3 | L2 | 18 |
| 4/17/2010 | | | NYY | L | | 3 | 4 | 13 | 6 | .684 | 6-4 | L3 | 19 |
| 4/17/2010 | | @ | Tex | L | | 6 | 7 | 13 | 7 | .650 | 5-5 | L4 | 20 |
| 4/18/2010 | | | NYY | W | Inge, B | 6 | 4 | 14 | 7 | .667 | 6-4 | W1 | 21 |
| 4/18/2010 | | @ | Tex | W | Gomez, C | 3 | 1 | 15 | 7 | .682 | 6-4 | W2 | 22 |
| 4/20/2010 | | | Tex | W | Zobrist, B | 6 | 2 | 16 | 7 | .696 | 6-4 | W3 | 23 |
| 4/20/2010 | | @ | NYY | W | Milledge, L | 11 | 4 | 17 | 7 | .708 | 6-4 | W4 | 24 |
| 4/21/2010 | | | Tex | W | Youkilis, K | 4 | 3 | 18 | 7 | .720 | 6-4 | W5 | 25 |
| 4/21/2010 | | @ | NYY | L | | 3 | 4 | 18 | 8 | .692 | 5-5 | L1 | 26 |
| 4/22/2010 | | | Tex | W | Zobrist, B | 3 | 0 | 19 | 8 | .704 | 6-4 | W1 | 27 |
| 4/22/2010 | | @ | NYY | L | | 1 | 2 | 19 | 9 | .679 | 6-4 | L1 | 28 |
| 5/13/2010 | | | Bos | L | | 4 | 5 | 19 | 10 | .655 | 6-4 | L2 | 29 |
| 5/13/2010 | | @ | Sea | L | | 0 | 7 | 19 | 11 | .633 | 6-4 | L3 | 30 |
| 5/14/2010 | | | Bos | L | | 2 | 4 | 19 | 12 | .613 | 5-5 | L4 | 31 |
| 5/14/2010 | | @ | Sea | L | | 3 | 4 | 19 | 13 | .594 | 4-6 | L5 | 32 |
| 5/15/2010 | | | Bos | W | LaRoche, A | 1 | 0 | 20 | 13 | .606 | 4-6 | W1 | 33 |
| 5/15/2010 | | @ | Sea | L | | 3 | 13 | 20 | 14 | .588 | 3-7 | L1 | 34 |
| 5/16/2010 | | | Bos | L | | 3 | 7 | 20 | 15 | .571 | 2-8 | L2 | 35 |
| 5/16/2010 | | @ | Sea | W | Zobrist, B | 7 | 4 | 21 | 15 | .583 | 3-7 | W1 | 36 |
| 5/17/2010 | | @ | LAA | W | Youkilis, K | 5 | 1 | 22 | 15 | .595 | 3-7 | W2 | 37 |
| 5/18/2010 | | @ | LAA | L | | 4 | 12 | 22 | 16 | .579 | 3-7 | L1 | 38 |
| 5/19/2010 | | @ | LAA | L | | 1 | 2 | 22 | 17 | .564 | 3-7 | L2 | 39 |
| 5/21/2010 | | | LAA | L | | 4 | 7 | 22 | 18 | .550 | 3-7 | L3 | 40 |
| 5/22/2010 | | | LAA | W | Youkilis, K | 10 | 4 | 23 | 18 | .561 | 4-6 | W1 | 41 |
| 5/23/2010 | | | LAA | W | Inge, B | 8 | 4 | 24 | 18 | .571 | 5-5 | W2 | 42 |
| 5/24/2010 | | @ | Bos | L | | 0 | 4 | 24 | 19 | .558 | 4-6 | L1 | 43 |
| 5/24/2010 | | | Sea | W | Lopez, F | 12 | 2 | 25 | 19 | .568 | 5-5 | W1 | 44 |
| 5/25/2010 | | @ | Bos | W | Mathis, J | 5 | 0 | 26 | 19 | .578 | 6-4 | W2 | 45 |
| 5/25/2010 | | | Sea | W | Youkilis, K | 7 | 0 | 27 | 19 | .587 | 6-4 | W3 | 46 |
| 5/26/2010 | | @ | Bos | L | | 2 | 4 | 27 | 20 | .574 | 5-5 | L1 | 47 |
| 5/26/2010 | | | Sea | W | Milledge, L | 4 | 3 | 28 | 20 | .583 | 6-4 | W1 | 48 |
| 5/27/2010 | | | Cle | L | | 4 | 5 | 28 | 21 | .571 | 6-4 | L1 | 49 |
| 5/27/2010 | | @ | Min | W | LaRoche, A | 2 | 0 | 29 | 21 | .580 | 7-3 | W1 | 50 |
| 5/28/2010 | | | Cle | W | Inge, B | 5 | 4 | 30 | 21 | .588 | 7-3 | W2 | 51 |
| 5/28/2010 | | @ | Min | L | | 1 | 7 | 30 | 22 | .577 | 6-4 | L1 | 52 |
| 5/29/2010 | | | Cle | W | Inge, B | 6 | 2 | 31 | 22 | .585 | 7-3 | W1 | 53 |
| 5/29/2010 | | @ | Min | L | | 2 | 7 | 31 | 23 | .574 | 6-4 | L1 | 54 |
| 6/14/2010 | | | Oak | W | Zobrist, B | 5 | 1 | 32 | 23 | .582 | 6-4 | W1 | 55 |
| 6/14/2010 | | @ | Tor | L | | 3 | 7 | 32 | 24 | .571 | 5-5 | L1 | 56 |
| 6/15/2010 | | | Oak | W | | 5 | 1 | 33 | 24 | .579 | 6-4 | W1 | 57 |
| 6/15/2010 | | @ | Tor | W | Gomez, C | 2 | 0 | 34 | 24 | .586 | 6-4 | W2 | 58 |
| 6/16/2010 | | | Oak | W | Inge, B | 6 | 5 | 35 | 24 | .593 | 7-3 | W3 | 59 |
| 6/16/2010 | | @ | Tor | W | Zobrist, B | 12 | 2 | 36 | 24 | .600 | 7-3 | W4 | 60 |
| 6/18/2010 | | @ | Bal | L | | 2 | 3 | 36 | 25 | .590 | 6-4 | L1 | 61 |
| 6/18/2010 | | | Tam | W | Youkilis, K | 9 | 2 | 37 | 25 | .597 | 7-3 | W1 | 62 |
| 6/19/2010 | | @ | Bal | L | | 3 | 5 | 37 | 26 | .587 | 6-4 | L1 | 63 |
| 6/19/2010 | | | Tam | W | Gross, G | 10 | 3 | 38 | 26 | .594 | 7-3 | W1 | 64 |
| 6/20/2010 | | @ | Bal | W | Gross, G | 3 | 2 | 39 | 26 | .600 | 7-3 | W2 | 65 |
| 6/20/2010 | | | Tam | W | Youkilis, K | 10 | 2 | 40 | 26 | .606 | 8-2 | W3 | 66 |
| 6/21/2010 | | @ | Bos | W | Zobrist, B | 6 | 2 | 41 | 26 | .612 | 8-2 | W4 | 67 |
| 6/21/2010 | | | Sea | L | | 1 | 4 | 41 | 27 | .603 | 7-3 | L1 | 68 |
| 6/22/2010 | | @ | Bos | L | | 1 | 4 | 41 | 28 | .594 | 6-4 | L2 | 69 |
| 6/22/2010 | | | Sea | W | Zobrist, B | 6 | 5 | 42 | 28 | .600 | 6-4 | W1 | 70 |
| 6/23/2010 | | @ | Bos | W | Zobrist, B | 4 | 1 | 43 | 28 | .606 | 7-3 | W2 | 71 |
| 6/23/2010 | | | Sea | L | | 8 | 9 | 43 | 29 | .597 | 6-4 | L1 | 72 |
| 6/25/2010 | | | Det | W | Gross, G | 10 | 5 | 44 | 29 | .603 | 7-3 | W1 | 73 |
| 6/25/2010 | | @ | KC | L | | 3 | 6 | 44 | 30 | .595 | 6-4 | L1 | 74 |
| 6/26/2010 | | | Det | W | Inge, B | 6 | 3 | 45 | 30 | .600 | 6-4 | W1 | 75 |
| 6/26/2010 | | @ | KC | W | Mathis, J | 8 | 3 | 46 | 30 | .605 | 6-4 | W2 | 76 |
| 6/27/2010 | | | Det | W | Escobar, Y | 5 | 2 | 47 | 30 | .610 | 6-4 | W3 | 77 |
| 6/27/2010 | | @ | KC | L | | 3 | 4 | 47 | 31 | .603 | 6-4 | L1 | 78 |
| 6/28/2010 | | | Det | W | Sweeney, R | 7 | 4 | 48 | 31 | .608 | 7-3 | W1 | 79 |
| 6/28/2010 | | @ | KC | W | Inge, B | 2 | 0 | 49 | 31 | .613 | 7-3 | W2 | 80 |
| 7/12/2010 | | | Min | L | | 1 | 6 | 49 | 32 | .605 | 6-4 | L1 | 81 |
| 7/12/2010 | | @ | Cle | L | | 1 | 8 | 49 | 33 | .598 | 6-4 | L2 | 82 |
| 7/13/2010 | | | Min | L | | 1 | 2 | 49 | 34 | .590 | 5-5 | L3 | 83 |
| 7/13/2010 | | @ | Cle | W | LaRoche, A | 6 | 0 | 50 | 34 | .595 | 6-4 | W1 | 84 |
| 7/14/2010 | | | Min | L | | 1 | 2 | 50 | 35 | .588 | 5-5 | L1 | 85 |
| 7/14/2010 | | @ | Cle | W | | 12 | 4 | 51 | 35 | .593 | 5-5 | W1 | 86 |
| 7/16/2010 | | | KC | W | Inge, B | 12 | 1 | 52 | 35 | .598 | 5-5 | W2 | 87 |
| 7/16/2010 | | @ | Det | W | Inge, B | 4 | 2 | 53 | 35 | .602 | 6-4 | W3 | 88 |
| 7/17/2010 | | | KC | W | Youkilis, K | 8 | 3 | 54 | 35 | .607 | 6-4 | W4 | 89 |
| 7/17/2010 | | @ | Det | W | Gross, G | 3 | 2 | 55 | 35 | .611 | 6-4 | W5 | 90 |
| 7/18/2010 | | | KC | W | Lopez, F | 13 | 6 | 56 | 35 | .615 | 7-3 | W6 | 91 |
| 7/18/2010 | | @ | Det | W | LaRoche, A | 13 | 2 | 57 | 35 | .620 | 8-2 | W7 | 92 |
| 7/19/2010 | | | NYY | W | Escobar, Y | 4 | 1 | 58 | 35 | .624 | 9-1 | W8 | 93 |
| 7/19/2010 | | @ | Tex | W | LaRoche, A | 9 | 7 | 59 | 35 | .628 | 9-1 | W9 | 94 |
| 7/20/2010 | | | NYY | W | Youkilis, K | 5 | 3 | 60 | 35 | .632 | 10-0 | W10 | 95 |
| 7/20/2010 | | @ | Tex | W | Inge, B | 9 | 1 | 61 | 35 | .635 | 10-0 | W11 | 96 |
| 7/21/2010 | | | NYY | W | Youkilis, K | 5 | 4 | 62 | 35 | .639 | 10-0 | W12 | 97 |
| 7/21/2010 | | @ | Tex | L | | 6 | 7 | 62 | 36 | .633 | 9-1 | L1 | 98 |
| 7/23/2010 | | | Tex | L | | 4 | 7 | 62 | 37 | .626 | 8-2 | L2 | 99 |
| 7/23/2010 | | @ | NYY | W | LaRoche, A | 9 | 2 | 63 | 37 | .630 | 8-2 | W1 | 100 |
| 7/24/2010 | | | Tex | W | Hanigan, R | 12 | 2 | 64 | 37 | .634 | 8-2 | W2 | 101 |
| 7/24/2010 | | @ | NYY | L | | 1 | 5 | 64 | 38 | .627 | 7-3 | L1 | 102 |
| 7/25/2010 | | | Tex | W | Youkilis, K | 10 | 5 | 65 | 38 | .631 | 7-3 | W1 | 103 |
| 7/25/2010 | | @ | NYY | W | | 6 | 3 | 66 | 38 | .635 | 7-3 | W2 | 104 |
| 7/27/2010 | | | Bos | W | Milledge, L | 3 | 1 | 67 | 38 | .638 | 7-3 | W3 | 105 |
| 7/27/2010 | | @ | Sea | L | | 7 | 10 | 67 | 39 | .632 | 6-4 | L1 | 106 |
| 7/28/2010 | | | Bos | L | | 4 | 5 | 67 | 40 | .626 | 5-5 | L2 | 107 |
| 7/28/2010 | | @ | Sea | L | | 4 | 6 | 67 | 41 | .620 | 5-5 | L3 | 108 |
| 8/12/2010 | | | Bal | L | | 0 | 5 | 67 | 42 | .615 | 5-5 | L4 | 109 |
| 8/12/2010 | | @ | Tam | W | Inge, B | 12 | 8 | 68 | 42 | .618 | 5-5 | W1 | 110 |
| 8/13/2010 | | | Bal | W | Hanigan, R | 3 | 0 | 69 | 42 | .622 | 5-5 | W2 | 111 |
| 8/13/2010 | | @ | Tam | W | LaRoche, A | 4 | 3 | 70 | 42 | .625 | 6-4 | W3 | 112 |
| 8/14/2010 | | | Bal | W | Sweeney, R | 7 | 1 | 71 | 42 | .628 | 6-4 | W4 | 113 |
| 8/14/2010 | | @ | Tam | W | Escobar, Y | 4 | 1 | 72 | 42 | .632 | 6-4 | W5 | 114 |
| 8/15/2010 | | | Bal | L | | 5 | 6 | 72 | 43 | .626 | 5-5 | L1 | 115 |
| 8/15/2010 | | @ | Tam | L | | 3 | 6 | 72 | 44 | .621 | 5-5 | L2 | 116 |
| 8/16/2010 | | @ | LAA | L | | 3 | 4 | 72 | 45 | .615 | 5-5 | L3 | 117 |
| 8/17/2010 | | @ | LAA | W | Lopez, F | 6 | 5 | 73 | 45 | .619 | 6-4 | W1 | 118 |
| 8/18/2010 | | @ | LAA | W | Lopez, F | 4 | 2 | 74 | 45 | .622 | 7-3 | W2 | 119 |
| 8/20/2010 | | | LAA | W | Inge, B | 5 | 2 | 75 | 45 | .625 | 7-3 | W3 | 120 |
| 8/21/2010 | | | LAA | W | | 1 | 0 | 76 | 45 | .628 | 7-3 | W4 | 121 |
| 8/22/2010 | | | LAA | W | Beltran, C | 4 | 2 | 77 | 45 | .631 | 7-3 | W5 | 122 |
| 8/23/2010 | | | Oak | W | Lopez, F | 4 | 1 | 78 | 45 | .634 | 7-3 | W6 | 123 |
| 8/23/2010 | | @ | Tor | W | Zobrist, B | 5 | 1 | 79 | 45 | .637 | 7-3 | W7 | 124 |
| 8/24/2010 | | | Oak | L | | 1 | 2 | 79 | 46 | .632 | 7-3 | L1 | 125 |
| 8/24/2010 | | @ | Tor | W | Zobrist, B | 6 | 4 | 80 | 46 | .635 | 8-2 | W1 | 126 |
| 8/25/2010 | | | Oak | L | | 3 | 4 | 80 | 47 | .630 | 8-2 | L1 | 127 |
| 8/25/2010 | | @ | Tor | W | Zobrist, B | 5 | 4 | 81 | 47 | .633 | 8-2 | W1 | 128 |
| 8/27/2010 | | | Cle | W | Youkilis, K | 10 | 5 | 82 | 47 | .636 | 8-2 | W2 | 129 |
| 8/27/2010 | | @ | Min | W | Zobrist, B | 3 | 2 | 83 | 47 | .638 | 8-2 | W3 | 130 |
| 8/28/2010 | | | Cle | W | Zobrist, B | 7 | 6 | 84 | 47 | .641 | 8-2 | W4 | 131 |
| 8/28/2010 | | @ | Min | W | Zobrist, B | 4 | 3 | 85 | 47 | .644 | 8-2 | W5 | 132 |
| 8/29/2010 | | | Cle | L | | 4 | 7 | 85 | 48 | .639 | 7-3 | L1 | 133 |
| 8/29/2010 | | @ | Min | L | | 0 | 1 | 85 | 49 | .634 | 6-4 | L2 | 134 |
| 9/12/2010 | | | Tor | W | | 6 | 1 | 86 | 49 | .637 | 7-3 | W1 | 135 |
| 9/12/2010 | | @ | Oak | L | | 2 | 6 | 86 | 50 | .632 | 6-4 | L1 | 136 |
| 9/13/2010 | | | Tor | W | Inge, B | 4 | 3 | 87 | 50 | .635 | 7-3 | W1 | 137 |
| 9/13/2010 | | @ | Oak | W | Gross, G | 6 | 2 | 88 | 50 | .638 | 7-3 | W2 | 138 |
| 9/14/2010 | | | Tor | W | Youkilis, K | 6 | 5 | 89 | 50 | .640 | 7-3 | W3 | 139 |
| 9/14/2010 | | @ | Oak | W | Youkilis, K | 7 | 3 | 90 | 50 | .643 | 7-3 | W4 | 140 |
| 9/15/2010 | | | Det | W | | 3 | 2 | 91 | 50 | .645 | 7-3 | W5 | 141 |
| 9/15/2010 | | @ | KC | L | | 2 | 8 | 91 | 51 | .641 | 6-4 | L1 | 142 |
| 9/16/2010 | | | Det | L | | 2 | 5 | 91 | 52 | .636 | 6-4 | L2 | 143 |
| 9/16/2010 | | @ | KC | W | LaRoche, A | 4 | 3 | 92 | 52 | .639 | 7-3 | W1 | 144 |
| 9/17/2010 | | | Det | W | Youkilis, K | 4 | 0 | 93 | 52 | .641 | 7-3 | W2 | 145 |
| 9/17/2010 | | @ | KC | W | Beltran, C | 12 | 1 | 94 | 52 | .644 | 8-2 | W3 | 146 |
| 9/18/2010 | | | KC | W | Inge, B | 8 | 6 | 95 | 52 | .646 | 8-2 | W4 | 147 |
| 9/18/2010 | | @ | Det | L | | 1 | 3 | 95 | 53 | .642 | 7-3 | L1 | 148 |
| 9/19/2010 | | | KC | W | Escobar, Y | 10 | 5 | 96 | 53 | .644 | 7-3 | W1 | 149 |
| 9/19/2010 | | @ | Det | W | Sweeney, R | 4 | 2 | 97 | 53 | .647 | 7-3 | W2 | 150 |
| 9/20/2010 | | | KC | L | | 3 | 7 | 97 | 54 | .642 | 6-4 | L1 | 151 |
| 9/20/2010 | | @ | Det | L | | 1 | 3 | 97 | 55 | .638 | 6-4 | L2 | 152 |
| 9/21/2010 | | | KC | W | Beltran, C | 10 | 3 | 98 | 55 | .641 | 7-3 | W1 | 153 |
| 9/21/2010 | | @ | Det | W | Hanigan, R | 8 | 3 | 99 | 55 | .643 | 7-3 | W2 | 154 |
| 9/23/2010 | | | Min | W | Escobar, Y | 6 | 5 | 100 | 55 | .645 | 7-3 | W3 | 155 |
| 9/23/2010 | | @ | Cle | L | | 0 | 1 | 100 | 56 | .641 | 6-4 | L1 | 156 |
| 9/24/2010 | | | Min | W | Sweeney, R | 2 | 1 | 101 | 56 | .643 | 6-4 | W1 | 157 |
| 9/24/2010 | | @ | Cle | W | Youkilis, K | 7 | 1 | 102 | 56 | .646 | 7-3 | W2 | 158 |
| 9/25/2010 | | | Min | W | Lopez, F | 6 | 1 | 103 | 56 | .648 | 7-3 | W3 | 159 |
| 9/25/2010 | | @ | Cle | W | Youkilis, K | 4 | 1 | 104 | 56 | .650 | 7-3 | W4 | 160 |
| 9/26/2010 | | | Min | W | Youkilis, K | 6 | 5 | 105 | 56 | .652 | 8-2 | W5 | 161 |
| 9/26/2010 | | @ | Cle | W | | 15 | 1 | 106 | 56 | .654 | 9-1 | W6 | 162 |