Organization pitching register - 2008
Regular season
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| David Aardsma | Min | mr | 26 | 18.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 3 | 2 | 2 | 0 | 1 | 1 | 0 |
| Jeremy Accardo | Ari | cl | 26 | 3.59 | 4 | 10 | 33 | 68 | 0 | 0 | 0 | 85.1 | 88 | 36 | 34 | 20 | 87 | 6 | 3 |
| Manny Acosta | StL | mr | 27 | 1.95 | 4 | 1 | 2 | 21 | 0 | 0 | 0 | 27.2 | 17 | 6 | 6 | 11 | 25 | 3 | 6 |
| Jeremy Affeldt* | Tam | mr | 29 | 3.67 | 4 | 4 | 3 | 73 | 0 | 0 | 0 | 103.0 | 74 | 45 | 42 | 57 | 90 | 1 | 12 |
| Jonathan Albaladejo | StL | mr | 25 | 2.96 | 1 | 1 | 1 | 18 | 0 | 0 | 0 | 27.1 | 18 | 10 | 9 | 9 | 22 | 4 | 5 |
| Matt Albers | Tam | sp | 25 | 5.88 | 7 | 7 | 0 | 26 | 26 | 0 | 0 | 111.2 | 144 | 78 | 73 | 48 | 86 | 16 | 7 |
| Greg Aquino | Cin | mr | 30 | 1.26 | 1 | 0 | 0 | 8 | 0 | 0 | 0 | 14.1 | 11 | 2 | 2 | 4 | 15 | 2 | 2 |
| Tony Armas | Col | mr | 30 | 6.13 | 3 | 11 | 0 | 21 | 21 | 1 | 1 | 120.1 | 129 | 86 | 82 | 53 | 102 | 23 | 3 |
| Bronson Arroyo | Atl | sp | 31 | 4.51 | 11 | 16 | 0 | 40 | 40 | 2 | 1 | 245.2 | 251 | 134 | 123 | 70 | 190 | 20 | 12 |
| Jose Ascanio | Ari | mr | 23 | 6.14 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 7.1 | 11 | 5 | 5 | 3 | 10 | 5 | 1 |
| Luis Ayala | LAD | mr | 30 | 4.60 | 1 | 1 | 1 | 23 | 0 | 0 | 0 | 29.1 | 27 | 16 | 15 | 11 | 19 | 2 | 1 |
| Brandon Backe | NYY | sp | 30 | 1.71 | 4 | 1 | 0 | 6 | 6 | 0 | 0 | 42.0 | 34 | 12 | 8 | 16 | 19 | 4 | 8 |
| Mike Bacsik* | Atl | sp | 30 | 4.20 | 8 | 9 | 0 | 23 | 22 | 0 | 0 | 137.0 | 164 | 75 | 64 | 37 | 49 | 21 | 24 |
| Cha Seung Baek | StL | sp | 28 | 4.84 | 6 | 5 | 0 | 14 | 14 | 1 | 1 | 93.0 | 117 | 58 | 50 | 22 | 64 | 9 | 6 |
| Danys Baez | Pit | mr | 30 | 5.70 | 2 | 8 | 0 | 59 | 0 | 0 | 0 | 90.0 | 104 | 64 | 57 | 39 | 50 | 14 | 9 |
| Homer Bailey | LAD | sp | 22 | 5.12 | 2 | 5 | 0 | 10 | 10 | 0 | 0 | 51.0 | 42 | 30 | 29 | 45 | 37 | 4 | 6 |
| Scott Baker | NYM | sp | 26 | 3.52 | 7 | 12 | 0 | 27 | 23 | 3 | 2 | 158.1 | 150 | 70 | 62 | 27 | 110 | 13 | 10 |
| John Bale* | LAD | mr | 34 | 3.00 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 3.0 | 3 | 1 | 1 | 2 | 3 | 0 | 1 |
| Josh Banks | SF | mr | 25 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Brian Bannister | ChW | sp | 27 | 4.33 | 10 | 8 | 0 | 28 | 28 | 2 | 0 | 174.2 | 178 | 91 | 84 | 56 | 86 | 15 | 24 |
| Daniel Barone | Ari | mr | 25 | 6.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 2 | 2 | 2 | 1 | 0 | 2 | 0 |
| Miguel Batista | Was | sp | 37 | 4.47 | 11 | 10 | 0 | 31 | 31 | 2 | 2 | 177.1 | 177 | 98 | 88 | 82 | 142 | 14 | 11 |
| Yorman Bazardo | LAA | mr | 23 | 2.21 | 2 | 0 | 0 | 12 | 0 | 0 | 0 | 20.1 | 13 | 7 | 5 | 6 | 9 | 1 | 3 |
| Josh Beckett | Flo | sp | 28 | 3.49 | 14 | 12 | 0 | 31 | 31 | 5 | 2 | 216.1 | 201 | 97 | 84 | 43 | 206 | 21 | 11 |
| Erik Bedard* | Tor | sp | 29 | 3.15 | 17 | 11 | 0 | 36 | 36 | 8 | 3 | 248.2 | 214 | 92 | 87 | 79 | 310 | 23 | 19 |
| Joe Beimel* | ChC | mr | 31 | 2.99 | 4 | 4 | 2 | 70 | 0 | 0 | 0 | 90.1 | 89 | 32 | 30 | 26 | 50 | 4 | 16 |
| Matt Belisle | NYY | sp | 28 | 6.05 | 4 | 15 | 0 | 29 | 29 | 1 | 0 | 165.0 | 221 | 116 | 111 | 59 | 120 | 30 | 20 |
| Heath Bell | Ari | mr | 30 | 2.60 | 9 | 2 | 3 | 80 | 0 | 0 | 0 | 103.2 | 79 | 33 | 30 | 27 | 102 | 4 | 7 |
| Armando Benitez | Tam | mr | 35 | 2.16 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 16.2 | 13 | 4 | 4 | 4 | 19 | 2 | 1 |
| Jeff Bennett | Oak | sp | 28 | 2.41 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 18.2 | 18 | 5 | 5 | 5 | 18 | 0 | 1 |
| Joaquin Benoit | Oak | mr | 30 | 2.05 | 2 | 5 | 1 | 57 | 0 | 0 | 0 | 109.2 | 90 | 27 | 25 | 31 | 111 | 6 | 5 |
| Jason Bergmann | Cin | sp | 26 | 4.19 | 6 | 12 | 0 | 24 | 24 | 1 | 0 | 148.1 | 131 | 74 | 69 | 69 | 125 | 24 | 6 |
| Rafael Betancourt | ChW | mr | 33 | 1.35 | 7 | 4 | 6 | 64 | 0 | 0 | 0 | 107.0 | 61 | 17 | 16 | 3 | 110 | 6 | 6 |
| Chad Billingsley | Ari | mr | 23 | 4.72 | 11 | 8 | 0 | 34 | 27 | 0 | 0 | 179.1 | 183 | 99 | 94 | 88 | 157 | 25 | 24 |
| Kurt Birkins* | LAA | mr | 27 | 7.71 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 4 | 2 | 2 | 1 | 2 | 0 | 1 |
| Travis Blackley* | Cin | sp | 25 | 8.16 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 14.1 | 18 | 13 | 13 | 11 | 5 | 4 | 5 |
| Joe Blanton | NYY | sp | 27 | 4.93 | 7 | 17 | 0 | 32 | 32 | 0 | 0 | 210.0 | 255 | 125 | 115 | 40 | 145 | 16 | 23 |
| Jeremy Bonderman | LAD | sp | 25 | 5.40 | 10 | 16 | 0 | 31 | 31 | 1 | 0 | 190.0 | 230 | 118 | 114 | 41 | 158 | 31 | 10 |
| Boof Bonser | LAA | sp | 26 | 3.69 | 5 | 4 | 0 | 12 | 12 | 0 | 0 | 75.2 | 72 | 36 | 31 | 22 | 56 | 8 | 3 |
| Chris Booker | Phi | mr | 31 | 28.93 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.2 | 12 | 15 | 15 | 9 | 1 | 1 | 0 |
| Chris Bootcheck | Min | mr | 29 | 6.68 | 1 | 0 | 2 | 24 | 0 | 0 | 0 | 33.2 | 46 | 25 | 25 | 9 | 29 | 6 | 3 |
| Dave Borkowski | Oak | mr | 31 | 3.29 | 1 | 0 | 2 | 27 | 0 | 0 | 0 | 38.1 | 41 | 17 | 14 | 18 | 30 | 5 | 5 |
| Joe Borowski | Sea | cl | 37 | 3.80 | 2 | 4 | 2 | 54 | 0 | 0 | 0 | 85.1 | 94 | 40 | 36 | 13 | 74 | 9 | 2 |
| Micah Bowie* | SD | mr | 33 | 2.79 | 5 | 0 | 0 | 10 | 9 | 0 | 0 | 48.1 | 42 | 16 | 15 | 28 | 35 | 2 | 6 |
| Blaine Boyer | Oak | mr | 26 | 0.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.2 | 5 | 0 | 0 | 0 | 1 | 0 | 0 |
| Dallas Braden* | Atl | sp | 24 | 5.94 | 3 | 3 | 0 | 14 | 12 | 0 | 0 | 69.2 | 82 | 47 | 46 | 21 | 53 | 16 | 4 |
| Chad Bradford | Ari | mr | 33 | 4.99 | 2 | 2 | 0 | 52 | 0 | 0 | 0 | 70.1 | 93 | 50 | 39 | 22 | 39 | 4 | 12 |
| Ryan Braun | NYY | mr | 27 | 5.85 | 0 | 0 | 0 | 24 | 0 | 0 | 0 | 47.2 | 61 | 33 | 31 | 25 | 33 | 9 | 4 |
| Chris Britton | Cin | mr | 25 | 0.40 | 3 | 0 | 1 | 15 | 0 | 0 | 0 | 22.2 | 9 | 1 | 1 | 9 | 6 | 1 | 1 |
| Lance Broadway | Flo | mr | 24 | 2.77 | 1 | 0 | 0 | 2 | 2 | 1 | 0 | 13.0 | 11 | 4 | 4 | 7 | 12 | 0 | 1 |
| Doug Brocail | Was | mr | 41 | 2.23 | 10 | 6 | 9 | 67 | 0 | 0 | 0 | 92.2 | 69 | 24 | 23 | 22 | 44 | 7 | 6 |
| Andrew Brown | Tam | mr | 27 | 2.99 | 7 | 2 | 4 | 36 | 0 | 0 | 0 | 69.1 | 55 | 26 | 23 | 22 | 77 | 5 | 6 |
| Jonathan Broxton | Flo | mr | 24 | 2.48 | 7 | 2 | 6 | 72 | 0 | 0 | 0 | 94.1 | 73 | 31 | 26 | 24 | 122 | 6 | 9 |
| Brian Bruney | Sea | mr | 26 | 4.97 | 4 | 1 | 1 | 42 | 0 | 0 | 0 | 54.1 | 51 | 32 | 30 | 35 | 51 | 5 | 5 |
| Clay Buchholz | Det | sp | 23 | 3.49 | 2 | 1 | 0 | 5 | 4 | 0 | 0 | 28.1 | 17 | 11 | 11 | 19 | 25 | 1 | 2 |
| Taylor Buchholz | Min | mr | 26 | 3.44 | 6 | 2 | 2 | 43 | 9 | 1 | 0 | 125.2 | 136 | 54 | 48 | 27 | 92 | 8 | 15 |
| Billy Buckner | Tex | sp | 24 | 5.36 | 0 | 3 | 0 | 6 | 6 | 1 | 0 | 40.1 | 37 | 29 | 24 | 18 | 21 | 8 | 5 |
| Mark Buehrle* | LAA | sp | 29 | 5.16 | 8 | 13 | 0 | 29 | 29 | 5 | 1 | 190.0 | 225 | 116 | 109 | 51 | 111 | 25 | 13 |
| Jason Bulger | ChC | mr | 29 | 1.23 | 1 | 1 | 0 | 7 | 0 | 0 | 0 | 14.2 | 10 | 2 | 2 | 5 | 9 | 0 | 2 |
| Bryan Bullington | Pit | sp | 27 | 6.15 | 3 | 3 | 0 | 7 | 6 | 0 | 0 | 26.1 | 38 | 18 | 18 | 10 | 8 | 5 | 2 |
| Ambiorix Burgos | Bos | mr | 24 | 0.50 | 5 | 2 | 1 | 23 | 0 | 0 | 0 | 36.1 | 13 | 2 | 2 | 18 | 37 | 2 | 1 |
| A.J. Burnett | Col | sp | 31 | 3.53 | 15 | 4 | 0 | 28 | 28 | 2 | 1 | 193.2 | 158 | 80 | 76 | 60 | 220 | 16 | 22 |
| Brian Burres* | Was | mr | 27 | 4.30 | 4 | 6 | 1 | 37 | 16 | 1 | 1 | 134.0 | 127 | 68 | 64 | 79 | 98 | 14 | 12 |
| Jared Burton | Bos | mr | 27 | 2.74 | 4 | 1 | 2 | 52 | 0 | 0 | 0 | 88.2 | 64 | 30 | 27 | 43 | 71 | 4 | 9 |
| Dave Bush | KC | sp | 28 | 5.11 | 10 | 21 | 0 | 35 | 35 | 1 | 0 | 202.2 | 229 | 123 | 115 | 80 | 161 | 17 | 12 |
| Paul Byrd | Pit | sp | 37 | 4.11 | 13 | 10 | 0 | 29 | 28 | 2 | 0 | 175.0 | 204 | 96 | 80 | 22 | 108 | 28 | 5 |
| Tim Byrdak* | Col | mr | 34 | 2.45 | 5 | 1 | 0 | 45 | 0 | 0 | 0 | 77.0 | 62 | 23 | 21 | 29 | 76 | 7 | 8 |
| Daniel Cabrera | Mil | sp | 27 | 4.51 | 11 | 19 | 0 | 35 | 33 | 1 | 0 | 213.2 | 220 | 117 | 107 | 91 | 187 | 28 | 15 |
| Fernando Cabrera | StL | mr | 26 | 2.25 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 3 | 1 | 1 | 2 | 6 | 0 | 0 |
| Matt Cain | SF | sp | 23 | 4.02 | 13 | 10 | 0 | 32 | 32 | 3 | 1 | 199.1 | 204 | 105 | 89 | 90 | 195 | 18 | 15 |
| Kiko Calero | ChW | mr | 33 | 6.94 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 11.2 | 12 | 11 | 9 | 4 | 9 | 2 | 1 |
| Kevin Cameron | Det | mr | 28 | 4.92 | 2 | 0 | 2 | 47 | 0 | 0 | 0 | 86.0 | 103 | 58 | 47 | 62 | 93 | 4 | 2 |
| Shawn Camp | Hou | mr | 32 | 10.92 | 1 | 3 | 0 | 42 | 0 | 0 | 0 | 57.2 | 119 | 74 | 70 | 18 | 58 | 12 | 8 |
| Jose Capellan | Hou | mr | 27 | 3.22 | 3 | 1 | 3 | 22 | 0 | 0 | 0 | 36.1 | 30 | 14 | 13 | 12 | 20 | 3 | 5 |
| Matt Capps | Was | mr | 24 | 1.78 | 6 | 2 | 33 | 51 | 0 | 0 | 0 | 60.2 | 48 | 12 | 12 | 15 | 49 | 4 | 2 |
| Chris Capuano* | NYY | sp | 29 | 5.33 | 7 | 18 | 0 | 26 | 26 | 1 | 0 | 158.2 | 194 | 97 | 94 | 66 | 146 | 18 | 11 |
| Buddy Carlyle | Atl | sp | 30 | 4.30 | 6 | 7 | 0 | 20 | 20 | 0 | 0 | 121.1 | 124 | 62 | 58 | 41 | 81 | 15 | 12 |
| Fausto Carmona | SD | sp | 27 | 3.03 | 19 | 9 | 0 | 33 | 32 | 3 | 1 | 223.0 | 195 | 81 | 75 | 58 | 135 | 15 | 34 |
| Chris Carpenter | Min | sp | 33 | 3.12 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 8.2 | 11 | 3 | 3 | 4 | 5 | 0 | 0 |
| Marcos Carvajal | Oak | mr | 23 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Santiago Casilla | Col | mr | 27 | 5.45 | 0 | 1 | 1 | 42 | 0 | 0 | 0 | 67.2 | 65 | 41 | 41 | 33 | 71 | 14 | 3 |
| Jack Cassel | Tex | sp | 27 | 4.08 | 1 | 0 | 0 | 6 | 5 | 0 | 0 | 28.2 | 41 | 13 | 13 | 17 | 15 | 1 | 6 |
| Fabio Castro* | ChW | mr | 23 | 11.25 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 4.0 | 5 | 5 | 5 | 9 | 2 | 0 | 1 |
| Gustavo Chacin* | LAD | sp | 27 | 5.25 | 1 | 1 | 0 | 7 | 7 | 0 | 0 | 36.0 | 40 | 22 | 21 | 4 | 17 | 6 | 5 |
| Shawn Chacon | Cin | mr | 30 | 4.75 | 3 | 2 | 1 | 67 | 0 | 0 | 0 | 106.0 | 107 | 63 | 56 | 65 | 85 | 15 | 15 |
| Joba Chamberlain | Oak | mr | 22 | 2.53 | 1 | 1 | 5 | 21 | 0 | 0 | 0 | 32.0 | 21 | 9 | 9 | 16 | 44 | 3 | 1 |
| Rocky Cherry | Was | mr | 28 | 1.21 | 1 | 0 | 1 | 18 | 0 | 0 | 0 | 22.1 | 16 | 3 | 3 | 7 | 17 | 2 | 3 |
| Matt Chico* | Det | sp | 25 | 6.13 | 10 | 7 | 0 | 32 | 32 | 0 | 0 | 152.2 | 181 | 115 | 104 | 75 | 96 | 19 | 13 |
| Vinnie Chulk | KC | mr | 29 | 2.55 | 8 | 5 | 1 | 76 | 0 | 0 | 0 | 116.1 | 104 | 36 | 33 | 42 | 99 | 6 | 8 |
| Roger Clemens | SD | sp | 45 | 3.65 | 14 | 1 | 0 | 20 | 20 | 0 | 0 | 125.2 | 127 | 57 | 51 | 36 | 81 | 11 | 11 |
| Tyler Clippard | Ari | sp | 23 | 2.76 | 3 | 1 | 0 | 6 | 6 | 0 | 0 | 32.2 | 27 | 11 | 10 | 11 | 20 | 6 | 2 |
| Todd Coffey | SF | mr | 27 | 8.64 | 1 | 3 | 0 | 31 | 0 | 0 | 0 | 41.2 | 70 | 43 | 40 | 18 | 28 | 6 | 7 |
| Jesus Colome | Pit | mr | 30 | 4.53 | 8 | 2 | 2 | 71 | 1 | 0 | 0 | 111.1 | 144 | 67 | 56 | 51 | 79 | 10 | 7 |
| Bartolo Colon | Tor | sp | 35 | 6.92 | 6 | 16 | 0 | 31 | 31 | 1 | 1 | 161.1 | 234 | 143 | 124 | 52 | 139 | 30 | 16 |
| Jose Contreras | Bal | sp | 36 | 6.55 | 4 | 20 | 0 | 29 | 29 | 3 | 0 | 169.0 | 215 | 135 | 123 | 71 | 107 | 24 | 17 |
| Aaron Cook | Atl | sp | 29 | 3.39 | 12 | 10 | 0 | 31 | 30 | 4 | 0 | 218.0 | 228 | 100 | 82 | 56 | 76 | 20 | 27 |
| Chad Cordero | SF | cl | 26 | 3.62 | 6 | 5 | 14 | 52 | 0 | 0 | 0 | 69.2 | 71 | 33 | 28 | 28 | 66 | 6 | 5 |
| Francisco Cordero | Oak | cl | 33 | 2.59 | 3 | 4 | 25 | 54 | 0 | 0 | 0 | 66.0 | 53 | 20 | 19 | 27 | 88 | 2 | 4 |
| Bryan Corey | Tam | mr | 34 | 3.38 | 2 | 2 | 0 | 7 | 0 | 0 | 0 | 13.1 | 14 | 5 | 5 | 10 | 10 | 1 | 5 |
| Lance Cormier | Flo | sp | 27 | 8.23 | 0 | 6 | 0 | 12 | 12 | 0 | 0 | 50.1 | 65 | 49 | 46 | 25 | 32 | 13 | 4 |
| Manny Corpas | Sea | mr | 25 | 1.45 | 4 | 2 | 31 | 62 | 0 | 0 | 0 | 74.2 | 46 | 13 | 12 | 14 | 55 | 4 | 8 |
| Kevin Correia | LAA | mr | 27 | 3.16 | 0 | 0 | 1 | 41 | 0 | 0 | 0 | 62.2 | 51 | 23 | 22 | 20 | 46 | 5 | 7 |
| Neal Cotts* | Tam | mr | 28 | 3.45 | 0 | 0 | 0 | 20 | 0 | 0 | 0 | 31.1 | 25 | 12 | 12 | 15 | 30 | 2 | 2 |
| Jon Coutlangus* | Det | mr | 27 | 5.96 | 1 | 1 | 1 | 51 | 0 | 0 | 0 | 54.1 | 66 | 39 | 36 | 46 | 56 | 7 | 7 |
| Juan Cruz | Det | mr | 29 | 2.75 | 10 | 4 | 5 | 58 | 0 | 0 | 0 | 85.0 | 55 | 28 | 26 | 49 | 117 | 6 | 3 |
| John Danks* | Col | sp | 23 | 7.15 | 5 | 13 | 0 | 29 | 29 | 1 | 0 | 168.2 | 221 | 140 | 134 | 61 | 132 | 40 | 11 |
| Kyle Davies | Cin | sp | 24 | 6.48 | 4 | 12 | 0 | 25 | 24 | 0 | 0 | 125.0 | 153 | 95 | 90 | 59 | 93 | 31 | 4 |
| Doug Davis* | StL | sp | 32 | 3.91 | 11 | 10 | 0 | 32 | 32 | 1 | 0 | 200.0 | 211 | 95 | 87 | 88 | 156 | 16 | 19 |
| Jorge De La Rosa* | Bos | sp | 27 | 5.22 | 4 | 9 | 0 | 28 | 27 | 0 | 0 | 112.0 | 136 | 73 | 65 | 42 | 72 | 12 | 12 |
| Manny Delcarmen | Cle | mr | 26 | 3.00 | 5 | 4 | 3 | 47 | 0 | 0 | 0 | 69.0 | 56 | 24 | 23 | 27 | 63 | 8 | 5 |
| Ryan Dempster | Min | cl | 31 | 2.61 | 8 | 4 | 9 | 65 | 0 | 0 | 0 | 82.2 | 60 | 30 | 24 | 26 | 61 | 8 | 11 |
| Julio DePaula | NYY | mr | 25 | 9.45 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 20.0 | 33 | 21 | 21 | 9 | 5 | 5 | 4 |
| Matt DeSalvo | Phi | sp | 27 | 11.54 | 1 | 5 | 0 | 7 | 7 | 1 | 0 | 36.2 | 62 | 52 | 47 | 24 | 10 | 3 | 2 |
| Ross Detwiler* | Tex | mr | 22 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Joey Devine | Hou | mr | 24 | 9.24 | 1 | 2 | 0 | 13 | 0 | 0 | 0 | 12.2 | 21 | 16 | 13 | 16 | 13 | 2 | 1 |
| Lenny DiNardo* | Tam | sp | 28 | 4.04 | 14 | 10 | 0 | 28 | 28 | 1 | 1 | 160.1 | 168 | 81 | 72 | 66 | 85 | 16 | 29 |
| Scott Dohmann | KC | mr | 30 | 2.55 | 3 | 4 | 2 | 42 | 0 | 0 | 0 | 67.0 | 48 | 20 | 19 | 28 | 57 | 5 | 11 |
| Brendan Donnelly | Tor | mr | 36 | 4.12 | 3 | 1 | 2 | 37 | 0 | 0 | 0 | 63.1 | 49 | 30 | 29 | 20 | 35 | 4 | 3 |
| Octavio Dotel | Ari | cl | 34 | 13.50 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 7 | 6 | 6 | 0 | 5 | 2 | 0 |
| Scott Downs* | LAA | mr | 32 | 3.21 | 9 | 4 | 3 | 53 | 0 | 0 | 0 | 61.2 | 58 | 24 | 22 | 25 | 64 | 2 | 4 |
| Brandon Duckworth | Was | mr | 32 | 2.35 | 2 | 1 | 1 | 26 | 2 | 0 | 0 | 53.2 | 42 | 15 | 14 | 28 | 31 | 2 | 10 |
| Zach Duke* | Oak | sp | 25 | 7.13 | 2 | 16 | 0 | 22 | 21 | 0 | 0 | 120.0 | 189 | 103 | 95 | 39 | 50 | 15 | 19 |
| Phil Dumatrait* | NYM | sp | 26 | 12.38 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 8.0 | 17 | 11 | 11 | 11 | 3 | 0 | 1 |
| Chad Durbin | Bos | sp | 30 | 4.73 | 6 | 11 | 0 | 28 | 27 | 0 | 0 | 150.1 | 154 | 90 | 79 | 69 | 87 | 19 | 9 |
| J.D. Durbin | SF | sp | 26 | 8.28 | 0 | 1 | 0 | 7 | 6 | 0 | 0 | 29.1 | 49 | 28 | 27 | 24 | 15 | 1 | 8 |
| Adam Eaton | Bal | sp | 30 | 7.78 | 3 | 14 | 0 | 23 | 22 | 0 | 0 | 105.1 | 135 | 102 | 91 | 67 | 59 | 21 | 14 |
| Scott Elarton | Mil | sp | 32 | 8.49 | 0 | 6 | 0 | 10 | 8 | 0 | 0 | 35.0 | 53 | 33 | 33 | 18 | 12 | 10 | 5 |
| Alan Embree* | Bos | cl | 38 | 5.38 | 6 | 7 | 3 | 78 | 0 | 0 | 0 | 87.0 | 102 | 57 | 52 | 18 | 67 | 11 | 10 |
| Kelvim Escobar | Bal | sp | 32 | 2.07 | 18 | 8 | 0 | 33 | 33 | 7 | 2 | 239.1 | 168 | 58 | 55 | 74 | 186 | 9 | 35 |
| Dana Eveland* | KC | mr | 24 | 15.00 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 6.0 | 12 | 10 | 10 | 6 | 3 | 1 | 0 |
| Scott Eyre* | Was | mr | 36 | 4.40 | 2 | 2 | 1 | 39 | 0 | 0 | 0 | 43.0 | 44 | 23 | 21 | 34 | 32 | 2 | 3 |
| Kyle Farnsworth | Cle | mr | 32 | 3.95 | 1 | 5 | 2 | 54 | 0 | 0 | 0 | 84.1 | 83 | 41 | 37 | 28 | 61 | 12 | 4 |
| Scott Feldman | Tex | mr | 25 | 6.79 | 1 | 1 | 1 | 37 | 0 | 0 | 0 | 63.2 | 65 | 51 | 48 | 52 | 45 | 5 | 8 |
| Pedro Feliciano* | Oak | mr | 31 | 4.90 | 6 | 6 | 1 | 61 | 0 | 0 | 0 | 90.0 | 87 | 54 | 49 | 48 | 83 | 6 | 15 |
| Randy Flores* | Ari | mr | 32 | 3.28 | 2 | 1 | 1 | 32 | 0 | 0 | 0 | 35.2 | 46 | 13 | 13 | 9 | 24 | 2 | 3 |
| Ron Flores* | NYY | mr | 28 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 2 | 0 | 0 | 0 | 3 | 0 | 0 |
| Gavin Floyd | LAA | sp | 25 | 7.08 | 2 | 2 | 0 | 4 | 4 | 0 | 0 | 20.1 | 23 | 16 | 16 | 7 | 18 | 6 | 2 |
| Josh Fogg | Ari | sp | 31 | 6.13 | 1 | 8 | 0 | 19 | 19 | 0 | 0 | 94.0 | 112 | 68 | 64 | 28 | 63 | 14 | 7 |
| Casey Fossum* | Pit | mr | 30 | 8.20 | 3 | 8 | 0 | 20 | 20 | 0 | 0 | 82.1 | 137 | 79 | 75 | 28 | 53 | 13 | 10 |
| Jeff Francis* | LAD | sp | 27 | 3.32 | 13 | 12 | 0 | 34 | 34 | 4 | 2 | 222.1 | 243 | 95 | 82 | 66 | 165 | 13 | 23 |
| Frank Francisco | Min | mr | 28 | 3.57 | 6 | 3 | 1 | 45 | 0 | 0 | 0 | 53.0 | 48 | 24 | 21 | 24 | 39 | 2 | 2 |
| Ryan Franklin | ChC | mr | 35 | 2.02 | 7 | 3 | 8 | 56 | 0 | 0 | 0 | 75.2 | 56 | 17 | 17 | 8 | 45 | 8 | 1 |
| Jason Frasor | StL | mr | 30 | 2.12 | 4 | 5 | 1 | 52 | 0 | 0 | 0 | 72.1 | 56 | 20 | 17 | 24 | 74 | 1 | 3 |
| Brian Fuentes* | Tor | cl | 32 | 2.98 | 4 | 7 | 27 | 50 | 0 | 0 | 0 | 66.1 | 58 | 28 | 22 | 33 | 69 | 4 | 0 |
| Aaron Fultz* | Tex | mr | 34 | 5.74 | 6 | 7 | 4 | 54 | 0 | 0 | 0 | 73.2 | 75 | 50 | 47 | 44 | 67 | 5 | 2 |
| Kason Gabbard* | LAD | sp | 26 | 4.08 | 7 | 6 | 0 | 18 | 18 | 2 | 0 | 110.1 | 86 | 52 | 50 | 50 | 78 | 13 | 13 |
| Eric Gagne | NYM | cl | 32 | 3.26 | 5 | 9 | 15 | 62 | 0 | 0 | 0 | 77.1 | 69 | 29 | 28 | 32 | 66 | 5 | 9 |
| Armando Galarraga | KC | mr | 26 | 5.36 | 3 | 11 | 0 | 19 | 19 | 0 | 0 | 92.1 | 81 | 59 | 55 | 64 | 65 | 18 | 5 |
| Sean Gallagher | Tex | mr | 22 | 10.80 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.1 | 3 | 4 | 4 | 6 | 1 | 0 | 1 |
| Yovani Gallardo | StL | sp | 22 | 3.90 | 8 | 6 | 0 | 20 | 20 | 3 | 1 | 136.0 | 138 | 69 | 59 | 40 | 121 | 18 | 14 |
| Freddy Garcia | Det | sp | 32 | 6.00 | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 15.0 | 15 | 12 | 10 | 5 | 14 | 4 | 0 |
| Harvey Garcia | SF | mr | 24 | 9.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.0 | 1 | 1 | 1 | 0 | 3 | 1 | 0 |
| Lee Gardner | Bos | mr | 33 | 2.96 | 4 | 6 | 7 | 69 | 0 | 0 | 0 | 100.1 | 95 | 37 | 33 | 23 | 57 | 3 | 15 |
| Jon Garland | Pit | sp | 28 | 3.45 | 13 | 10 | 0 | 32 | 32 | 5 | 0 | 211.1 | 211 | 93 | 81 | 50 | 91 | 15 | 21 |
| Matt Garza | Oak | sp | 24 | 4.54 | 4 | 7 | 0 | 17 | 17 | 2 | 0 | 107.0 | 110 | 66 | 54 | 36 | 104 | 11 | 10 |
| Chad Gaudin | NYM | sp | 25 | 4.70 | 7 | 14 | 0 | 34 | 34 | 1 | 1 | 191.2 | 188 | 105 | 100 | 96 | 148 | 22 | 22 |
| Geoff Geary | Flo | mr | 31 | 4.09 | 5 | 0 | 1 | 58 | 0 | 0 | 0 | 99.0 | 119 | 50 | 45 | 35 | 63 | 6 | 15 |
| Justin Germano | StL | sp | 25 | 3.26 | 7 | 9 | 0 | 25 | 25 | 0 | 0 | 163.0 | 144 | 68 | 59 | 39 | 96 | 17 | 9 |
| Tom Glavine* | ChC | sp | 42 | 6.54 | 13 | 5 | 0 | 28 | 27 | 2 | 1 | 150.0 | 202 | 121 | 109 | 55 | 68 | 25 | 17 |
| Gary Glover | Mil | mr | 31 | 4.05 | 1 | 1 | 2 | 65 | 0 | 0 | 0 | 91.0 | 98 | 44 | 41 | 27 | 79 | 14 | 7 |
| Jimmy Gobble* | Flo | mr | 26 | 9.24 | 1 | 3 | 1 | 34 | 0 | 0 | 0 | 38.0 | 60 | 39 | 39 | 14 | 33 | 7 | 4 |
| Edgar Gonzalez | Col | mr | 25 | 5.50 | 6 | 8 | 0 | 18 | 18 | 3 | 0 | 121.0 | 131 | 76 | 74 | 40 | 75 | 17 | 13 |
| Mike Gonzalez* | Atl | mr | 30 | 5.23 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 10.1 | 13 | 6 | 6 | 10 | 8 | 0 | 0 |
| Tom Gordon | Phi | mr | 40 | 6.48 | 3 | 3 | 1 | 47 | 0 | 0 | 0 | 76.1 | 87 | 64 | 55 | 41 | 61 | 16 | 8 |
| Tom Gorzelanny* | Pit | sp | 25 | 4.55 | 7 | 13 | 0 | 33 | 33 | 0 | 0 | 194.0 | 220 | 115 | 98 | 69 | 137 | 20 | 12 |
| John Grabow* | Bal | mr | 29 | 4.79 | 4 | 2 | 1 | 60 | 0 | 0 | 0 | 88.1 | 99 | 50 | 47 | 43 | 72 | 7 | 9 |
| Sean Green | Min | mr | 29 | 3.42 | 1 | 2 | 2 | 39 | 0 | 0 | 0 | 47.1 | 57 | 19 | 18 | 21 | 41 | 2 | 9 |
| Kevin Gregg | Det | cl | 30 | 2.97 | 6 | 5 | 14 | 72 | 0 | 0 | 0 | 109.0 | 72 | 36 | 36 | 54 | 127 | 8 | 7 |
| Zack Greinke | LAA | mr | 24 | 4.21 | 10 | 12 | 0 | 31 | 31 | 2 | 2 | 194.1 | 203 | 100 | 91 | 47 | 185 | 22 | 12 |
| Jason Grilli | Phi | mr | 31 | 5.93 | 3 | 7 | 3 | 56 | 0 | 0 | 0 | 71.1 | 96 | 54 | 47 | 27 | 66 | 8 | 5 |
| Eddie Guardado* | Mil | mr | 37 | 7.20 | 0 | 2 | 2 | 18 | 0 | 0 | 0 | 20.0 | 33 | 16 | 16 | 8 | 15 | 3 | 3 |
| Matt Guerrier | Sea | mr | 29 | 3.18 | 3 | 4 | 5 | 53 | 0 | 0 | 0 | 73.2 | 73 | 32 | 26 | 19 | 61 | 8 | 7 |
| Jeremy Guthrie | Min | sp | 29 | 2.93 | 17 | 8 | 0 | 34 | 29 | 4 | 2 | 218.0 | 189 | 83 | 71 | 67 | 156 | 25 | 27 |
| Juan Gutierrez | SD | mr | 24 | 5.02 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 14.1 | 14 | 8 | 8 | 2 | 10 | 2 | 1 |
| Roy Halladay | Hou | sp | 31 | 3.34 | 14 | 9 | 0 | 32 | 32 | 11 | 2 | 231.2 | 235 | 103 | 86 | 45 | 136 | 16 | 29 |
| Cole Hamels* | Flo | sp | 24 | 3.72 | 11 | 7 | 0 | 29 | 29 | 0 | 0 | 191.0 | 161 | 84 | 79 | 58 | 193 | 19 | 13 |
| Jason Hammel | Sea | sp | 25 | 6.08 | 2 | 0 | 0 | 13 | 1 | 0 | 0 | 23.2 | 27 | 16 | 16 | 8 | 13 | 5 | 3 |
| Justin Hampson* | SD | mr | 28 | 3.44 | 2 | 3 | 0 | 43 | 0 | 0 | 0 | 55.0 | 55 | 24 | 21 | 14 | 38 | 4 | 3 |
| Joel Hanrahan | NYM | sp | 26 | 12.51 | 0 | 4 | 0 | 5 | 4 | 0 | 0 | 13.2 | 28 | 21 | 19 | 11 | 6 | 4 | 0 |
| Aaron Harang | Cle | sp | 30 | 4.24 | 21 | 9 | 0 | 34 | 34 | 3 | 2 | 240.0 | 233 | 118 | 113 | 71 | 224 | 24 | 15 |
| Rich Harden | Col | sp | 26 | 2.66 | 2 | 2 | 0 | 4 | 4 | 0 | 0 | 23.2 | 13 | 7 | 7 | 6 | 33 | 3 | 1 |
| Dan Haren | LAA | sp | 27 | 3.15 | 15 | 11 | 0 | 33 | 33 | 3 | 1 | 234.1 | 200 | 96 | 82 | 53 | 195 | 27 | 11 |
| Kevin Hart | LAA | mr | 25 | 1.80 | 1 | 1 | 0 | 8 | 0 | 0 | 0 | 15.0 | 4 | 5 | 3 | 8 | 14 | 0 | 3 |
| LaTroy Hawkins | Tex | mr | 35 | 4.95 | 1 | 3 | 11 | 50 | 0 | 0 | 0 | 67.1 | 70 | 37 | 37 | 21 | 39 | 6 | 7 |
| Aaron Heilman | Hou | mr | 29 | 2.52 | 8 | 4 | 4 | 72 | 0 | 0 | 0 | 110.2 | 95 | 34 | 31 | 22 | 92 | 7 | 5 |
| Mark Hendrickson* | Sea | mr | 34 | 4.42 | 13 | 7 | 2 | 41 | 18 | 0 | 0 | 146.2 | 152 | 82 | 72 | 40 | 117 | 17 | 12 |
| Sean Henn* | Flo | mr | 27 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Brad Hennessey | Flo | cl | 28 | 4.65 | 0 | 2 | 1 | 45 | 0 | 0 | 0 | 69.2 | 77 | 40 | 36 | 32 | 47 | 10 | 12 |
| Clay Hensley | Ari | sp | 28 | 3.52 | 1 | 0 | 0 | 8 | 0 | 0 | 0 | 15.1 | 17 | 7 | 6 | 8 | 11 | 1 | 4 |
| Matt Herges | Pit | mr | 38 | 1.53 | 6 | 3 | 2 | 34 | 0 | 0 | 0 | 53.0 | 25 | 9 | 9 | 8 | 33 | 6 | 3 |
| Felix Hernandez | Bal | sp | 22 | 4.10 | 12 | 13 | 0 | 34 | 34 | 1 | 0 | 208.1 | 243 | 104 | 95 | 74 | 196 | 20 | 25 |
| Livan Hernandez | Atl | sp | 33 | 6.44 | 12 | 20 | 0 | 38 | 38 | 3 | 0 | 211.0 | 268 | 166 | 151 | 92 | 87 | 42 | 20 |
| Orlando Hernandez | ChC | sp | 38 | 4.28 | 16 | 4 | 0 | 28 | 26 | 2 | 0 | 162.0 | 132 | 79 | 77 | 80 | 141 | 32 | 10 |
| Roberto Hernandez | Atl | mr | 43 | 7.85 | 1 | 6 | 2 | 43 | 0 | 0 | 0 | 55.0 | 79 | 50 | 48 | 22 | 31 | 7 | 6 |
| Rich Hill* | ChC | sp | 28 | 3.92 | 12 | 12 | 0 | 31 | 31 | 1 | 0 | 193.0 | 164 | 88 | 84 | 73 | 176 | 30 | 8 |
| Shawn Hill | Tam | sp | 27 | 4.74 | 5 | 12 | 0 | 21 | 21 | 1 | 1 | 138.2 | 135 | 77 | 73 | 46 | 95 | 15 | 12 |
| Jason Hirsh | Ari | sp | 26 | 5.88 | 7 | 8 | 0 | 18 | 18 | 0 | 0 | 104.0 | 112 | 73 | 68 | 40 | 69 | 24 | 9 |
| Luke Hochevar | Mil | mr | 24 | 2.61 | 0 | 0 | 1 | 3 | 1 | 0 | 0 | 10.1 | 7 | 5 | 3 | 2 | 1 | 0 | 1 |
| Jim Hoey | NYM | mr | 25 | 9.00 | 0 | 2 | 0 | 15 | 0 | 0 | 0 | 17.0 | 23 | 17 | 17 | 19 | 9 | 2 | 3 |
| Trevor Hoffman | SD | cl | 40 | 2.06 | 4 | 1 | 0 | 52 | 0 | 0 | 0 | 78.2 | 63 | 21 | 18 | 13 | 50 | 4 | 3 |
| D.J. Houlton | Flo | mr | 28 | 6.35 | 1 | 1 | 0 | 8 | 0 | 0 | 0 | 17.0 | 18 | 12 | 12 | 6 | 13 | 2 | 1 |
| J.P. Howell* | Flo | sp | 25 | 6.49 | 2 | 1 | 0 | 8 | 8 | 0 | 0 | 34.2 | 49 | 25 | 25 | 11 | 40 | 5 | 2 |
| Bob Howry | ChC | mr | 34 | 3.03 | 2 | 0 | 1 | 61 | 0 | 0 | 0 | 101.0 | 90 | 34 | 34 | 28 | 85 | 9 | 9 |
| Tim Hudson | Min | sp | 32 | 3.72 | 15 | 11 | 0 | 34 | 34 | 5 | 2 | 232.1 | 229 | 118 | 96 | 60 | 168 | 16 | 31 |
| Phil Hughes | SF | sp | 22 | 3.82 | 6 | 6 | 0 | 16 | 16 | 2 | 1 | 106.0 | 87 | 46 | 45 | 43 | 84 | 12 | 4 |
| Philip Humber | LAA | mr | 25 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Kei Igawa* | KC | sp | 28 | 7.09 | 5 | 18 | 0 | 33 | 33 | 0 | 0 | 167.2 | 181 | 145 | 132 | 96 | 137 | 36 | 14 |
| Jason Isringhausen | LAA | cl | 35 | 2.98 | 4 | 6 | 13 | 37 | 0 | 0 | 0 | 45.1 | 27 | 15 | 15 | 17 | 36 | 8 | 9 |
| Edwin Jackson | Hou | sp | 24 | 4.27 | 17 | 7 | 0 | 33 | 33 | 0 | 0 | 173.0 | 180 | 89 | 82 | 67 | 148 | 22 | 11 |
| Chuck James* | ChW | sp | 26 | 4.58 | 10 | 7 | 0 | 25 | 25 | 0 | 0 | 127.2 | 128 | 73 | 65 | 50 | 96 | 24 | 3 |
| Casey Janssen | LAA | mr | 26 | 4.52 | 3 | 6 | 3 | 45 | 0 | 0 | 0 | 65.2 | 64 | 40 | 33 | 29 | 36 | 2 | 5 |
| Bobby Jenks | Pit | cl | 27 | 1.06 | 4 | 2 | 30 | 66 | 0 | 0 | 0 | 93.0 | 61 | 17 | 11 | 9 | 80 | 1 | 4 |
| Jason Jennings | Cle | sp | 29 | 4.93 | 4 | 3 | 0 | 9 | 9 | 1 | 1 | 49.1 | 56 | 27 | 27 | 19 | 39 | 5 | 2 |
| Ubaldo Jimenez | NYY | sp | 24 | 6.35 | 4 | 10 | 0 | 15 | 15 | 0 | 0 | 85.0 | 89 | 72 | 60 | 44 | 71 | 15 | 6 |
| Josh Johnson | NYY | sp | 24 | 19.57 | 0 | 4 | 0 | 5 | 5 | 0 | 0 | 13.1 | 31 | 31 | 29 | 16 | 9 | 6 | 4 |
| Randy Johnson* | NYM | sp | 44 | 3.69 | 1 | 7 | 0 | 13 | 13 | 1 | 0 | 83.0 | 68 | 34 | 34 | 19 | 114 | 16 | 3 |
| Tyler Johnson* | Cle | mr | 27 | 2.93 | 1 | 2 | 4 | 36 | 0 | 0 | 0 | 43.0 | 30 | 14 | 14 | 10 | 35 | 2 | 1 |
| Todd Jones | ChC | cl | 40 | 3.23 | 6 | 0 | 4 | 60 | 0 | 0 | 0 | 100.1 | 101 | 40 | 36 | 27 | 50 | 7 | 14 |
| Jorge Julio | Phi | mr | 29 | 7.12 | 4 | 3 | 1 | 47 | 0 | 0 | 0 | 79.2 | 100 | 71 | 63 | 47 | 80 | 9 | 11 |
| Jair Jurrjens | Mil | sp | 22 | 2.04 | 1 | 1 | 0 | 7 | 5 | 0 | 0 | 35.1 | 20 | 8 | 8 | 13 | 15 | 4 | 2 |
| Jeff Karstens | Cin | mr | 25 | 11.47 | 0 | 2 | 0 | 5 | 4 | 0 | 0 | 13.1 | 26 | 22 | 17 | 14 | 5 | 2 | 1 |
| Scott Kazmir* | SF | sp | 24 | 3.31 | 13 | 10 | 0 | 34 | 34 | 1 | 0 | 209.2 | 200 | 83 | 77 | 83 | 237 | 14 | 15 |
| Kyle Kendrick | LAD | sp | 23 | 4.57 | 10 | 6 | 0 | 21 | 21 | 2 | 0 | 126.0 | 142 | 65 | 64 | 29 | 43 | 21 | 20 |
| Ian Kennedy | Phi | sp | 23 | 3.38 | 1 | 1 | 0 | 4 | 4 | 0 | 0 | 26.2 | 27 | 12 | 10 | 12 | 25 | 2 | 1 |
| Joe Kennedy* | Phi | mr | 29 | 7.24 | 8 | 13 | 0 | 25 | 25 | 0 | 0 | 136.2 | 173 | 118 | 110 | 63 | 59 | 21 | 11 |
| Logan Kensing | Mil | mr | 25 | 3.29 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 13.2 | 6 | 5 | 5 | 5 | 12 | 1 | 2 |
| Byung-Hyun Kim | Tam | sp | 29 | 4.13 | 1 | 4 | 0 | 14 | 14 | 0 | 0 | 52.1 | 46 | 25 | 24 | 28 | 45 | 8 | 2 |
| Ray King* | KC | mr | 34 | 6.75 | 1 | 1 | 1 | 68 | 0 | 0 | 0 | 78.2 | 85 | 60 | 59 | 60 | 44 | 12 | 11 |
| Steve Kline* | StL | mr | 35 | 5.77 | 2 | 1 | 3 | 40 | 0 | 0 | 0 | 53.0 | 80 | 40 | 34 | 18 | 19 | 4 | 5 |
| Mike Koplove | Col | mr | 31 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 2 | 2 | 0 | 2 | 1 | 0 | 0 |
| Hong-Chih Kuo* | Sea | sp | 26 | 0.93 | 1 | 0 | 0 | 4 | 1 | 0 | 0 | 9.2 | 6 | 1 | 1 | 3 | 3 | 0 | 2 |
| John Lackey | Hou | sp | 29 | 3.47 | 16 | 6 | 0 | 34 | 34 | 3 | 0 | 238.2 | 249 | 99 | 92 | 46 | 202 | 23 | 25 |
| Aaron Laffey* | ChW | sp | 23 | 4.11 | 5 | 1 | 0 | 10 | 10 | 2 | 2 | 70.0 | 66 | 32 | 32 | 14 | 37 | 4 | 19 |
| John Lannan* | Mil | sp | 23 | 8.90 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 31.1 | 50 | 33 | 31 | 19 | 3 | 3 | 6 |
| Brian Lawrence | Phi | sp | 32 | 14.04 | 0 | 6 | 0 | 6 | 6 | 0 | 0 | 25.0 | 52 | 45 | 39 | 20 | 15 | 5 | 2 |
| Cliff Lee* | Cle | sp | 29 | 7.21 | 5 | 7 | 0 | 19 | 19 | 0 | 0 | 92.1 | 124 | 84 | 74 | 41 | 67 | 19 | 4 |
| Jon Lester* | Sea | sp | 24 | 3.38 | 7 | 4 | 0 | 15 | 15 | 1 | 0 | 85.1 | 68 | 32 | 32 | 35 | 51 | 7 | 7 |
| Jensen Lewis | Min | mr | 24 | 1.83 | 4 | 2 | 14 | 31 | 0 | 0 | 0 | 39.1 | 32 | 8 | 8 | 15 | 41 | 2 | 1 |
| Brad Lidge | Atl | cl | 31 | 2.95 | 8 | 8 | 32 | 79 | 0 | 0 | 0 | 97.2 | 77 | 35 | 32 | 26 | 134 | 14 | 6 |
| Jon Lieber | Phi | sp | 38 | 6.78 | 4 | 6 | 0 | 13 | 13 | 2 | 0 | 77.0 | 108 | 61 | 58 | 23 | 64 | 7 | 10 |
| Ted Lilly* | Hou | sp | 32 | 3.56 | 14 | 6 | 0 | 33 | 33 | 4 | 3 | 225.0 | 202 | 97 | 89 | 53 | 189 | 29 | 13 |
| Tim Lincecum | Tor | sp | 24 | 4.38 | 7 | 11 | 0 | 27 | 27 | 1 | 0 | 154.0 | 151 | 84 | 75 | 61 | 171 | 21 | 5 |
| Matt Lindstrom | Bos | mr | 28 | 2.34 | 5 | 7 | 20 | 72 | 0 | 0 | 0 | 96.0 | 103 | 28 | 25 | 41 | 94 | 4 | 10 |
| Scott Linebrink | Mil | mr | 31 | 5.02 | 3 | 6 | 3 | 66 | 0 | 0 | 0 | 86.0 | 84 | 53 | 48 | 30 | 74 | 15 | 8 |
| Jesse Litsch | Cin | sp | 23 | 3.21 | 7 | 3 | 0 | 16 | 16 | 0 | 0 | 106.2 | 95 | 41 | 38 | 37 | 44 | 10 | 19 |
| Wes Littleton | Cin | mr | 25 | 3.22 | 3 | 3 | 4 | 46 | 0 | 0 | 0 | 64.1 | 53 | 25 | 23 | 18 | 26 | 11 | 8 |
| Bobby Livingston* | Col | sp | 25 | 6.83 | 8 | 11 | 0 | 28 | 28 | 2 | 0 | 162.0 | 248 | 129 | 123 | 23 | 88 | 22 | 16 |
| Radhames Liz | Bal | mr | 25 | 6.98 | 0 | 4 | 1 | 12 | 6 | 0 | 0 | 38.2 | 39 | 30 | 30 | 41 | 35 | 9 | 2 |
| Esteban Loaiza | Flo | sp | 36 | 12.54 | 1 | 5 | 0 | 8 | 8 | 0 | 0 | 28.0 | 47 | 46 | 39 | 25 | 18 | 16 | 1 |
| Kameron Loe | Bos | sp | 26 | 6.24 | 4 | 11 | 2 | 33 | 28 | 0 | 0 | 150.0 | 190 | 111 | 104 | 57 | 107 | 20 | 19 |
| Adam Loewen* | LAA | sp | 24 | 2.50 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 18.0 | 10 | 6 | 5 | 11 | 19 | 1 | 1 |
| Boone Logan* | Cle | mr | 23 | 3.60 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 15.0 | 18 | 8 | 6 | 8 | 6 | 2 | 2 |
| Kyle Lohse | Bal | sp | 29 | 4.64 | 9 | 15 | 0 | 31 | 31 | 3 | 0 | 188.0 | 207 | 111 | 97 | 83 | 125 | 14 | 18 |
| Braden Looper | Cle | sp | 33 | 3.65 | 20 | 4 | 0 | 32 | 32 | 6 | 1 | 222.0 | 203 | 98 | 90 | 59 | 133 | 24 | 28 |
| Aquilino Lopez | Sea | mr | 33 | 6.75 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
| Javier Lopez* | Col | mr | 30 | 5.23 | 2 | 7 | 2 | 51 | 0 | 0 | 0 | 63.2 | 59 | 38 | 37 | 33 | 36 | 9 | 7 |
| Rodrigo Lopez | StL | sp | 32 | 4.36 | 6 | 9 | 0 | 17 | 17 | 1 | 0 | 109.1 | 124 | 58 | 53 | 33 | 61 | 11 | 10 |
| Derek Lowe | ChW | sp | 35 | 3.84 | 17 | 8 | 0 | 32 | 32 | 4 | 1 | 210.2 | 200 | 100 | 90 | 89 | 155 | 23 | 25 |
| Mark Lowe | StL | mr | 25 | 15.00 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 3.0 | 7 | 5 | 5 | 2 | 3 | 1 | 0 |
| Noah Lowry* | Mil | sp | 27 | 5.18 | 8 | 14 | 0 | 28 | 28 | 0 | 0 | 156.1 | 180 | 102 | 90 | 95 | 103 | 29 | 23 |
| Ruddy Lugo | KC | mr | 28 | 5.56 | 0 | 4 | 1 | 54 | 0 | 0 | 0 | 103.2 | 104 | 70 | 64 | 56 | 82 | 13 | 7 |
| Brandon Lyon | Tam | mr | 28 | 2.40 | 8 | 7 | 3 | 72 | 0 | 0 | 0 | 105.0 | 88 | 30 | 28 | 34 | 65 | 3 | 8 |
| Mike MacDougal | Bal | mr | 31 | 4.56 | 1 | 0 | 0 | 22 | 0 | 0 | 0 | 25.2 | 33 | 18 | 13 | 14 | 28 | 3 | 0 |
| Greg Maddux | ChC | sp | 42 | 4.00 | 19 | 8 | 0 | 35 | 35 | 1 | 1 | 214.0 | 244 | 103 | 95 | 31 | 134 | 20 | 16 |
| Ryan Madson | NYM | mr | 27 | 2.40 | 6 | 0 | 0 | 52 | 0 | 0 | 0 | 93.2 | 76 | 27 | 25 | 28 | 69 | 4 | 9 |
| Ron Mahay* | Det | mr | 37 | 3.34 | 5 | 2 | 4 | 62 | 0 | 0 | 0 | 72.2 | 65 | 30 | 27 | 46 | 72 | 3 | 6 |
| Paul Maholm* | LAA | sp | 26 | 4.66 | 9 | 9 | 0 | 24 | 24 | 1 | 0 | 150.2 | 154 | 81 | 78 | 41 | 91 | 22 | 16 |
| John Maine | Oak | sp | 27 | 3.71 | 14 | 13 | 0 | 34 | 33 | 3 | 0 | 213.2 | 174 | 97 | 88 | 77 | 208 | 24 | 12 |
| Gary Majewski | Tex | mr | 28 | 6.75 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 16.0 | 24 | 14 | 12 | 1 | 10 | 3 | 1 |
| Shaun Marcum | Tam | sp | 26 | 3.26 | 17 | 7 | 0 | 30 | 30 | 2 | 2 | 201.2 | 172 | 77 | 73 | 57 | 161 | 33 | 21 |
| Carlos Marmol | Tam | mr | 25 | 1.32 | 4 | 3 | 34 | 59 | 0 | 0 | 0 | 81.2 | 45 | 13 | 12 | 41 | 108 | 1 | 5 |
| Jason Marquis | StL | sp | 29 | 3.99 | 13 | 12 | 0 | 30 | 30 | 1 | 0 | 191.2 | 204 | 91 | 85 | 80 | 108 | 17 | 25 |
| Jay Marshall* | Det | mr | 25 | 5.71 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 17.1 | 25 | 13 | 11 | 9 | 9 | 1 | 3 |
| Sean Marshall* | Flo | sp | 25 | 3.61 | 10 | 6 | 0 | 24 | 24 | 1 | 0 | 147.0 | 145 | 68 | 59 | 45 | 89 | 18 | 14 |
| Damaso Marte* | Ari | mr | 33 | 2.85 | 6 | 2 | 5 | 64 | 0 | 0 | 0 | 66.1 | 53 | 24 | 21 | 28 | 78 | 3 | 3 |
| Tom Martin* | Atl | mr | 38 | 7.04 | 2 | 2 | 2 | 65 | 0 | 0 | 0 | 94.2 | 142 | 80 | 74 | 35 | 33 | 20 | 4 |
| Carlos Martinez | Cin | mr | 26 | 20.25 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.0 | 7 | 9 | 9 | 2 | 2 | 4 | 0 |
| Pedro Martinez | Bos | sp | 36 | 2.65 | 3 | 1 | 0 | 6 | 6 | 0 | 0 | 34.0 | 35 | 12 | 10 | 10 | 45 | 2 | 0 |
| Nick Masset | Oak | mr | 26 | 19.50 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 6.0 | 12 | 13 | 13 | 7 | 3 | 2 | 0 |
| Tom Mastny | KC | mr | 27 | 4.65 | 3 | 3 | 2 | 64 | 0 | 0 | 0 | 127.2 | 132 | 72 | 66 | 50 | 130 | 15 | 13 |
| Julio Mateo | Cin | mr | 30 | 2.92 | 0 | 1 | 2 | 7 | 0 | 0 | 0 | 12.1 | 15 | 5 | 4 | 2 | 5 | 1 | 1 |
| Daisuke Matsuzaka | Cle | sp | 27 | 3.86 | 22 | 6 | 0 | 32 | 32 | 1 | 1 | 219.1 | 181 | 98 | 94 | 100 | 215 | 23 | 19 |
| Marcus McBeth | Bos | mr | 27 | 27.00 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 1.0 | 3 | 3 | 3 | 1 | 0 | 0 | 0 |
| Macay McBride* | Ari | mr | 25 | 3.04 | 0 | 0 | 0 | 26 | 0 | 0 | 0 | 23.2 | 16 | 9 | 8 | 12 | 22 | 0 | 4 |
| Brandon McCarthy | Ari | sp | 24 | 4.47 | 3 | 3 | 0 | 8 | 8 | 0 | 0 | 46.1 | 52 | 23 | 23 | 17 | 30 | 3 | 4 |
| Seth McClung | Mil | mr | 27 | 5.87 | 0 | 1 | 1 | 11 | 0 | 0 | 0 | 15.1 | 17 | 11 | 10 | 14 | 13 | 0 | 0 |
| Dustin McGowan | Sea | sp | 26 | 2.84 | 21 | 3 | 0 | 30 | 30 | 2 | 1 | 203.0 | 153 | 66 | 64 | 71 | 165 | 8 | 23 |
| Marty McLeary | NYM | mr | 33 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Mark McLemore* | NYY | mr | 27 | 8.82 | 0 | 2 | 0 | 12 | 0 | 0 | 0 | 16.1 | 22 | 17 | 16 | 13 | 20 | 3 | 0 |
| Gil Meche | Sea | sp | 29 | 3.31 | 21 | 7 | 0 | 34 | 34 | 4 | 1 | 242.1 | 216 | 98 | 89 | 49 | 166 | 25 | 35 |
| Brandon Medders | NYY | mr | 28 | 5.25 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 24.0 | 21 | 14 | 14 | 10 | 23 | 6 | 2 |
| Luis Mendoza | Mil | sp | 24 | 1.59 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 11.1 | 9 | 2 | 2 | 2 | 6 | 1 | 1 |
| Cla Meredith | Col | mr | 25 | 4.87 | 5 | 8 | 2 | 75 | 0 | 0 | 0 | 94.1 | 128 | 54 | 51 | 20 | 74 | 9 | 18 |
| Jose Mesa | NYM | mr | 42 | 3.93 | 0 | 2 | 0 | 24 | 0 | 0 | 0 | 34.1 | 33 | 18 | 15 | 18 | 18 | 4 | 4 |
| Randy Messenger | Phi | mr | 26 | 6.89 | 1 | 5 | 0 | 54 | 0 | 0 | 0 | 82.1 | 128 | 69 | 63 | 29 | 52 | 13 | 10 |
| Dan Meyer* | Oak | sp | 26 | 9.95 | 2 | 4 | 0 | 7 | 6 | 0 | 0 | 31.2 | 51 | 36 | 35 | 22 | 16 | 8 | 1 |
| Andrew Miller* | Mil | sp | 23 | 10.97 | 1 | 10 | 0 | 13 | 13 | 0 | 0 | 53.1 | 86 | 68 | 65 | 46 | 48 | 13 | 6 |
| Justin Miller | LAD | mr | 30 | 3.56 | 2 | 1 | 2 | 41 | 0 | 0 | 0 | 60.2 | 56 | 24 | 24 | 25 | 69 | 4 | 5 |
| Trever Miller* | Phi | mr | 35 | 5.97 | 2 | 2 | 2 | 23 | 0 | 0 | 0 | 37.2 | 54 | 27 | 25 | 19 | 30 | 6 | 3 |
| Kevin Millwood | StL | sp | 33 | 3.87 | 8 | 9 | 0 | 23 | 23 | 0 | 0 | 148.2 | 167 | 78 | 64 | 40 | 106 | 10 | 11 |
| Zach Miner | Pit | mr | 26 | 4.34 | 1 | 4 | 1 | 29 | 2 | 0 | 0 | 56.0 | 74 | 30 | 27 | 18 | 27 | 4 | 7 |
| Patrick Misch* | NYM | mr | 26 | 7.07 | 0 | 2 | 0 | 8 | 1 | 0 | 0 | 14.0 | 23 | 11 | 11 | 1 | 6 | 1 | 2 |
| Sergio Mitre | Cin | sp | 27 | 4.28 | 6 | 11 | 0 | 26 | 26 | 1 | 1 | 147.1 | 176 | 76 | 70 | 46 | 81 | 10 | 18 |
| Brian Moehler | Tor | mr | 36 | 3.71 | 2 | 0 | 4 | 60 | 0 | 0 | 0 | 131.0 | 139 | 55 | 54 | 41 | 88 | 12 | 24 |
| Franklin Morales* | Flo | sp | 22 | 3.31 | 6 | 3 | 0 | 11 | 11 | 0 | 0 | 65.1 | 57 | 26 | 24 | 23 | 41 | 6 | 6 |
| Juan Morillo | Bos | mr | 24 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Matt Morris | Oak | sp | 33 | 4.53 | 15 | 12 | 0 | 34 | 34 | 2 | 0 | 222.1 | 249 | 126 | 112 | 67 | 121 | 24 | 24 |
| Brandon Morrow | LAA | mr | 23 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.2 | 1 | 0 | 0 | 3 | 3 | 0 | 0 |
| Dustin Moseley | Was | mr | 26 | 2.49 | 4 | 4 | 0 | 37 | 7 | 1 | 1 | 105.0 | 91 | 34 | 29 | 29 | 44 | 5 | 13 |
| Guillermo Mota | Bal | mr | 34 | 4.10 | 0 | 3 | 0 | 44 | 0 | 0 | 0 | 74.2 | 76 | 35 | 34 | 22 | 65 | 5 | 4 |
| Jamie Moyer* | Phi | sp | 45 | 5.76 | 9 | 17 | 0 | 34 | 34 | 6 | 1 | 222.0 | 288 | 169 | 142 | 61 | 154 | 41 | 14 |
| Peter Moylan | Cin | mr | 29 | 3.94 | 6 | 4 | 19 | 79 | 0 | 0 | 0 | 112.0 | 99 | 53 | 49 | 25 | 86 | 12 | 10 |
| Arnie Munoz* | Phi | mr | 26 | 10.95 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 12.1 | 21 | 15 | 15 | 16 | 7 | 3 | 3 |
| A.J. Murray* | Det | mr | 26 | 4.34 | 1 | 0 | 0 | 15 | 3 | 0 | 0 | 29.0 | 29 | 15 | 14 | 16 | 20 | 5 | 3 |
| Mike Mussina | SD | sp | 39 | 6.11 | 10 | 7 | 0 | 30 | 30 | 0 | 0 | 150.1 | 220 | 113 | 102 | 40 | 97 | 22 | 13 |
| Brett Myers | LAA | cl | 27 | 3.46 | 3 | 1 | 12 | 58 | 0 | 0 | 0 | 80.2 | 61 | 31 | 31 | 46 | 97 | 6 | 3 |
| Mike Myers* | Tex | mr | 39 | 3.47 | 1 | 1 | 0 | 46 | 0 | 0 | 0 | 72.2 | 63 | 33 | 28 | 24 | 26 | 8 | 5 |
| Joe Nathan | ChW | cl | 33 | 1.77 | 7 | 3 | 30 | 67 | 0 | 0 | 0 | 71.1 | 49 | 19 | 14 | 10 | 83 | 2 | 6 |
| Pat Neshek | Ari | mr | 27 | 2.05 | 8 | 4 | 3 | 70 | 0 | 0 | 0 | 88.0 | 54 | 25 | 20 | 23 | 93 | 7 | 2 |
| Dustin Nippert | ChW | mr | 27 | 5.57 | 0 | 3 | 1 | 12 | 0 | 0 | 0 | 32.1 | 39 | 21 | 20 | 10 | 31 | 7 | 3 |
| Ricky Nolasco | Cin | sp | 25 | 5.13 | 2 | 2 | 0 | 4 | 4 | 0 | 0 | 26.1 | 39 | 17 | 15 | 7 | 15 | 4 | 1 |
| Leo Nunez | NYM | mr | 24 | 3.78 | 2 | 2 | 1 | 11 | 7 | 0 | 0 | 47.2 | 38 | 20 | 20 | 7 | 41 | 11 | 2 |
| Eric O'Flaherty* | NYM | mr | 23 | 4.50 | 1 | 7 | 1 | 63 | 0 | 0 | 0 | 82.0 | 93 | 46 | 41 | 39 | 61 | 3 | 7 |
| Tomo Ohka | Mil | sp | 32 | 2.47 | 5 | 4 | 0 | 12 | 11 | 0 | 0 | 73.0 | 66 | 28 | 20 | 29 | 35 | 4 | 11 |
| Ross Ohlendorf | NYM | mr | 25 | 10.80 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.1 | 3 | 4 | 4 | 3 | 3 | 0 | 0 |
| Will Ohman* | StL | mr | 30 | 4.33 | 1 | 4 | 2 | 42 | 0 | 0 | 0 | 43.2 | 44 | 21 | 21 | 18 | 31 | 2 | 4 |
| Hideki Okajima* | SD | mr | 32 | 0.95 | 7 | 1 | 2 | 63 | 0 | 0 | 0 | 85.0 | 50 | 9 | 9 | 24 | 63 | 1 | 4 |
| Darren Oliver* | Cle | mr | 37 | 4.93 | 4 | 1 | 0 | 37 | 0 | 0 | 0 | 45.2 | 53 | 29 | 25 | 24 | 45 | 4 | 1 |
| Scott Olsen* | Hou | sp | 24 | 6.75 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 17.1 | 24 | 14 | 13 | 9 | 15 | 2 | 1 |
| Garrett Olson* | Was | sp | 24 | 8.76 | 1 | 3 | 0 | 4 | 4 | 0 | 0 | 12.1 | 19 | 13 | 12 | 10 | 6 | 3 | 2 |
| Ramon Ortiz | Pit | mr | 35 | 5.05 | 11 | 7 | 0 | 24 | 23 | 1 | 0 | 137.1 | 153 | 78 | 77 | 23 | 69 | 24 | 12 |
| Russ Ortiz | StL | sp | 34 | 15.00 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 6.0 | 13 | 10 | 10 | 0 | 3 | 4 | 0 |
| Chad Orvella | Col | mr | 27 | 16.20 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 1.2 | 5 | 3 | 3 | 2 | 1 | 1 | 0 |
| Franquelis Osoria | Tex | mr | 26 | 3.45 | 1 | 1 | 0 | 8 | 0 | 0 | 0 | 15.2 | 15 | 6 | 6 | 5 | 9 | 2 | 1 |
| Roy Oswalt | Ari | sp | 30 | 5.28 | 9 | 16 | 0 | 32 | 32 | 2 | 1 | 202.2 | 217 | 125 | 119 | 68 | 147 | 16 | 19 |
| Akinori Otsuka | Tex | mr | 36 | 2.20 | 2 | 2 | 11 | 32 | 0 | 0 | 0 | 41.0 | 35 | 14 | 10 | 14 | 27 | 2 | 4 |
| Henry Owens | NYY | mr | 29 | 3.74 | 3 | 1 | 1 | 18 | 0 | 0 | 0 | 21.2 | 17 | 10 | 9 | 11 | 16 | 3 | 1 |
| Micah Owings | LAA | sp | 25 | 3.29 | 13 | 6 | 0 | 26 | 26 | 0 | 0 | 169.2 | 146 | 64 | 62 | 58 | 123 | 17 | 17 |
| Vicente Padilla | Flo | sp | 30 | 4.63 | 8 | 7 | 0 | 26 | 26 | 0 | 0 | 144.0 | 168 | 78 | 74 | 60 | 102 | 9 | 17 |
| Jonathan Papelbon | LAD | cl | 27 | 1.60 | 6 | 3 | 32 | 59 | 0 | 0 | 0 | 73.0 | 39 | 14 | 13 | 16 | 93 | 7 | 3 |
| Manny Parra* | Hou | mr | 25 | 7.36 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 14.2 | 20 | 16 | 12 | 9 | 10 | 0 | 3 |
| John Parrish* | Min | mr | 30 | 8.65 | 1 | 2 | 0 | 37 | 0 | 0 | 0 | 26.0 | 40 | 25 | 25 | 23 | 25 | 2 | 2 |
| Troy Patton* | Cle | sp | 22 | 16.50 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 12.0 | 24 | 23 | 22 | 11 | 11 | 7 | 1 |
| Felipe Paulino | Mil | sp | 24 | 6.92 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 13.0 | 19 | 15 | 10 | 4 | 4 | 5 | 2 |
| Carl Pavano | NYY | sp | 32 | 3.43 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 21.0 | 20 | 10 | 8 | 6 | 10 | 0 | 2 |
| Jake Peavy | SD | sp | 27 | 2.69 | 27 | 3 | 0 | 34 | 34 | 3 | 3 | 240.2 | 199 | 82 | 72 | 59 | 266 | 16 | 13 |
| Mike Pelfrey | NYM | sp | 24 | 7.04 | 1 | 9 | 0 | 16 | 15 | 1 | 0 | 70.1 | 98 | 58 | 55 | 37 | 40 | 7 | 8 |
| Tony Pena | SF | mr | 26 | 3.77 | 5 | 6 | 17 | 70 | 0 | 0 | 0 | 105.0 | 82 | 46 | 44 | 39 | 92 | 10 | 9 |
| Brad Penny | Tam | sp | 30 | 5.06 | 11 | 10 | 0 | 30 | 30 | 1 | 0 | 178.0 | 192 | 105 | 100 | 83 | 124 | 16 | 24 |
| Joel Peralta | Tam | mr | 32 | 4.76 | 2 | 3 | 0 | 57 | 0 | 0 | 0 | 121.0 | 144 | 69 | 64 | 25 | 82 | 21 | 13 |
| Troy Percival | SD | mr | 38 | 2.74 | 6 | 3 | 3 | 38 | 2 | 0 | 0 | 69.0 | 49 | 22 | 21 | 25 | 59 | 2 | 0 |
| Odalis Perez* | Cin | sp | 31 | 4.85 | 4 | 15 | 0 | 29 | 29 | 1 | 0 | 169.0 | 192 | 100 | 91 | 61 | 84 | 17 | 22 |
| Oliver Perez* | Min | sp | 26 | 3.97 | 11 | 12 | 0 | 32 | 32 | 0 | 0 | 188.0 | 182 | 102 | 83 | 97 | 171 | 20 | 11 |
| Rafael Perez* | NYY | mr | 26 | 1.73 | 1 | 4 | 25 | 43 | 0 | 0 | 0 | 62.1 | 34 | 16 | 12 | 8 | 67 | 5 | 4 |
| Glen Perkins* | Pit | mr | 25 | 2.59 | 1 | 0 | 0 | 17 | 0 | 0 | 0 | 24.1 | 18 | 7 | 7 | 15 | 18 | 0 | 1 |
| Yusmeiro Petit | Tam | sp | 23 | 4.20 | 5 | 4 | 0 | 13 | 13 | 0 | 0 | 64.1 | 68 | 30 | 30 | 27 | 51 | 8 | 7 |
| Billy Petrick | Min | mr | 24 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Andy Pettitte* | Tex | sp | 36 | 5.50 | 13 | 15 | 0 | 35 | 35 | 4 | 1 | 224.1 | 292 | 148 | 137 | 82 | 150 | 16 | 33 |
| Joel Pineiro | Bal | mr | 29 | 6.25 | 4 | 5 | 2 | 44 | 7 | 0 | 0 | 90.2 | 106 | 63 | 63 | 33 | 58 | 18 | 7 |
| Renyel Pinto* | Bos | mr | 25 | 5.98 | 2 | 4 | 0 | 55 | 0 | 0 | 0 | 61.2 | 56 | 42 | 41 | 66 | 73 | 9 | 8 |
| Sidney Ponson | Flo | sp | 31 | 22.85 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 4.1 | 14 | 11 | 11 | 1 | 5 | 4 | 0 |
| Scott Proctor | LAA | mr | 31 | 4.91 | 1 | 0 | 2 | 31 | 0 | 0 | 0 | 44.0 | 39 | 26 | 24 | 21 | 37 | 8 | 3 |
| J.J. Putz | SD | cl | 31 | 0.67 | 2 | 0 | 54 | 72 | 0 | 0 | 0 | 80.1 | 33 | 6 | 6 | 14 | 75 | 4 | 9 |
| Chad Qualls | LAD | mr | 29 | 3.72 | 5 | 5 | 0 | 52 | 0 | 0 | 0 | 75.0 | 84 | 34 | 31 | 21 | 79 | 6 | 6 |
| Edwar Ramirez | NYY | mr | 27 | 6.23 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 8.2 | 12 | 6 | 6 | 6 | 18 | 1 | 0 |
| Elizardo Ramirez | Phi | sp | 25 | 5.32 | 0 | 2 | 0 | 4 | 4 | 1 | 0 | 23.2 | 25 | 15 | 14 | 13 | 16 | 4 | 1 |
| Horacio Ramirez* | KC | sp | 28 | 6.06 | 5 | 17 | 0 | 33 | 33 | 0 | 0 | 160.1 | 218 | 115 | 108 | 75 | 53 | 22 | 27 |
| Ramon Ramirez | Col | mr | 26 | 3.34 | 1 | 3 | 0 | 19 | 0 | 0 | 0 | 29.2 | 31 | 11 | 11 | 5 | 15 | 2 | 4 |
| Darrell Rasner | Tex | sp | 27 | 8.10 | 0 | 4 | 0 | 7 | 7 | 0 | 0 | 40.0 | 53 | 37 | 36 | 17 | 17 | 9 | 4 |
| Jon Rauch | ChW | mr | 29 | 2.80 | 7 | 1 | 1 | 56 | 0 | 0 | 0 | 90.0 | 83 | 32 | 28 | 14 | 76 | 5 | 4 |
| Chris Ray | Flo | cl | 26 | 3.67 | 8 | 7 | 2 | 45 | 0 | 0 | 0 | 54.0 | 46 | 23 | 22 | 14 | 60 | 8 | 2 |
| Tim Redding | SF | sp | 30 | 4.23 | 7 | 4 | 0 | 18 | 18 | 0 | 0 | 110.2 | 110 | 56 | 52 | 55 | 64 | 9 | 10 |
| Mark Redman* | ChC | sp | 34 | 14.54 | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 4.1 | 11 | 7 | 7 | 3 | 2 | 1 | 1 |
| Al Reyes | Flo | cl | 38 | 3.27 | 5 | 1 | 1 | 46 | 0 | 0 | 0 | 63.1 | 47 | 26 | 23 | 19 | 81 | 13 | 1 |
| Anthony Reyes | Hou | sp | 26 | 4.04 | 7 | 10 | 0 | 23 | 23 | 0 | 0 | 129.1 | 132 | 68 | 58 | 44 | 83 | 22 | 7 |
| Dennys Reyes* | Bal | mr | 31 | 9.75 | 1 | 1 | 0 | 30 | 0 | 0 | 0 | 36.0 | 49 | 39 | 39 | 35 | 28 | 4 | 11 |
| Jo-Jo Reyes* | Ari | sp | 23 | 5.04 | 2 | 4 | 0 | 10 | 10 | 0 | 0 | 55.1 | 51 | 33 | 31 | 38 | 34 | 9 | 4 |
| John Rheinecker* | StL | mr | 29 | 2.08 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 4.1 | 5 | 2 | 1 | 5 | 4 | 0 | 0 |
| Juan Rincon | Tex | mr | 29 | 4.75 | 2 | 8 | 5 | 57 | 0 | 0 | 0 | 89.0 | 89 | 54 | 47 | 47 | 70 | 15 | 11 |
| David Riske | Bal | mr | 31 | 4.06 | 5 | 7 | 26 | 66 | 0 | 0 | 0 | 82.0 | 66 | 37 | 37 | 27 | 64 | 7 | 8 |
| Mariano Rivera | Flo | cl | 38 | 4.12 | 3 | 8 | 40 | 67 | 0 | 0 | 0 | 74.1 | 79 | 35 | 34 | 13 | 68 | 7 | 10 |
| Saul Rivera | Cin | mr | 30 | 4.70 | 6 | 10 | 1 | 79 | 0 | 0 | 0 | 103.1 | 118 | 58 | 54 | 50 | 62 | 4 | 14 |
| Nate Robertson* | Was | sp | 30 | 3.87 | 15 | 8 | 0 | 32 | 32 | 0 | 0 | 193.0 | 195 | 100 | 83 | 77 | 108 | 17 | 23 |
| Fernando Rodney | KC | mr | 31 | 6.08 | 4 | 7 | 25 | 56 | 0 | 0 | 0 | 63.2 | 66 | 43 | 43 | 26 | 67 | 12 | 4 |
| Francisco Rodriguez | Col | cl | 26 | 3.25 | 5 | 3 | 30 | 60 | 0 | 0 | 0 | 72.0 | 51 | 27 | 26 | 31 | 107 | 5 | 5 |
| Wandy Rodriguez* | Min | sp | 29 | 4.77 | 12 | 6 | 0 | 32 | 32 | 3 | 2 | 173.2 | 190 | 100 | 92 | 74 | 123 | 10 | 15 |
| Kenny Rogers* | NYM | sp | 43 | 4.57 | 2 | 9 | 0 | 14 | 14 | 0 | 0 | 82.2 | 92 | 48 | 42 | 28 | 43 | 11 | 7 |
| J.C. Romero* | Was | mr | 32 | 3.33 | 2 | 4 | 1 | 42 | 0 | 0 | 0 | 48.2 | 29 | 18 | 18 | 39 | 30 | 0 | 13 |
| Ryan Rowland-Smith* | SF | mr | 25 | 5.79 | 0 | 5 | 3 | 25 | 0 | 0 | 0 | 28.0 | 34 | 19 | 18 | 15 | 32 | 5 | 4 |
| Jae Kuk Ryu | Sea | mr | 25 | 10.80 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 3.1 | 6 | 4 | 4 | 6 | 4 | 0 | 1 |
| Kirk Saarloos | Phi | mr | 29 | 10.10 | 0 | 3 | 0 | 26 | 4 | 0 | 0 | 49.0 | 70 | 55 | 55 | 31 | 33 | 17 | 4 |
| C.C. Sabathia* | ChW | sp | 27 | 4.40 | 16 | 12 | 0 | 34 | 34 | 3 | 1 | 220.2 | 252 | 111 | 108 | 31 | 180 | 23 | 20 |
| Takashi Saito | SD | cl | 38 | 0.46 | 10 | 1 | 2 | 66 | 0 | 0 | 0 | 98.1 | 39 | 6 | 5 | 20 | 122 | 1 | 8 |
| Juan Salas | NYY | mr | 29 | 4.07 | 3 | 3 | 1 | 28 | 0 | 0 | 0 | 42.0 | 36 | 21 | 19 | 22 | 34 | 7 | 3 |
| Brad Salmon | Bal | mr | 28 | 6.75 | 1 | 0 | 1 | 23 | 0 | 0 | 0 | 30.2 | 40 | 24 | 23 | 11 | 33 | 6 | 3 |
| Chris Sampson | Min | sp | 30 | 5.08 | 8 | 8 | 0 | 25 | 22 | 1 | 0 | 124.0 | 147 | 71 | 70 | 35 | 55 | 23 | 14 |
| Anibal Sanchez | Bos | sp | 24 | 8.53 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 6.1 | 10 | 6 | 6 | 2 | 3 | 1 | 0 |
| Jonathan Sanchez* | KC | mr | 25 | 0.90 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 10.0 | 7 | 1 | 1 | 5 | 12 | 0 | 0 |
| Romulo Sanchez | Col | mr | 24 | 7.00 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 9.0 | 9 | 7 | 7 | 7 | 10 | 2 | 1 |
| Ervin Santana | Bos | sp | 25 | 6.46 | 4 | 15 | 0 | 29 | 29 | 0 | 0 | 149.0 | 181 | 115 | 107 | 56 | 144 | 34 | 7 |
| Johan Santana* | Mil | sp | 29 | 3.96 | 10 | 11 | 0 | 29 | 29 | 0 | 0 | 193.0 | 184 | 92 | 85 | 37 | 210 | 37 | 14 |
| Victor Santos | NYY | mr | 31 | 9.63 | 0 | 1 | 0 | 20 | 2 | 0 | 0 | 43.0 | 64 | 46 | 46 | 21 | 38 | 11 | 7 |
| Dennis Sarfate | Sea | mr | 27 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 4 | 0 | 0 | 0 | 5 | 0 | 0 |
| Joe Saunders* | SF | sp | 27 | 4.34 | 9 | 8 | 0 | 21 | 21 | 2 | 0 | 132.2 | 151 | 68 | 64 | 39 | 102 | 6 | 8 |
| Curt Schilling | Mil | sp | 41 | 3.59 | 8 | 12 | 0 | 25 | 25 | 2 | 0 | 170.2 | 190 | 77 | 68 | 26 | 116 | 17 | 11 |
| Jason Schmidt | Phi | sp | 35 | 7.55 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 39.1 | 53 | 36 | 33 | 17 | 32 | 9 | 2 |
| Scott Schoeneweis* | NYM | mr | 34 | 6.10 | 2 | 4 | 2 | 62 | 0 | 0 | 0 | 76.2 | 85 | 54 | 52 | 40 | 54 | 16 | 11 |
| Chris Schroder | Tor | mr | 29 | 3.59 | 6 | 2 | 2 | 56 | 0 | 0 | 0 | 77.2 | 65 | 32 | 31 | 27 | 68 | 8 | 3 |
| Rudy Seanez | Tor | mr | 39 | 6.26 | 3 | 8 | 0 | 44 | 0 | 0 | 0 | 54.2 | 73 | 41 | 38 | 28 | 53 | 9 | 5 |
| Bobby Seay* | NYY | mr | 30 | 0.89 | 2 | 1 | 1 | 28 | 0 | 0 | 0 | 30.1 | 21 | 4 | 3 | 8 | 24 | 1 | 5 |
| Chris Seddon* | Cin | sp | 24 | 11.68 | 0 | 3 | 1 | 9 | 0 | 0 | 0 | 12.1 | 22 | 16 | 16 | 11 | 8 | 3 | 1 |
| Zack Segovia | Tor | sp | 25 | 27.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1.1 | 4 | 5 | 4 | 1 | 1 | 0 | 0 |
| Aaron Sele | NYY | mr | 38 | 6.43 | 0 | 2 | 0 | 31 | 0 | 0 | 0 | 49.0 | 78 | 44 | 35 | 24 | 32 | 3 | 8 |
| Jae Seo | LAD | sp | 31 | 9.22 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 13.2 | 21 | 14 | 14 | 6 | 7 | 5 | 4 |
| Tom Shearn | Flo | sp | 30 | 4.14 | 6 | 2 | 0 | 9 | 9 | 0 | 0 | 54.1 | 56 | 27 | 25 | 22 | 30 | 10 | 6 |
| Ben Sheets | Tex | sp | 29 | 3.75 | 11 | 10 | 0 | 27 | 27 | 2 | 0 | 180.0 | 164 | 84 | 75 | 57 | 136 | 24 | 11 |
| George Sherrill* | Min | mr | 31 | 2.06 | 5 | 5 | 11 | 69 | 0 | 0 | 0 | 83.0 | 59 | 19 | 19 | 35 | 99 | 6 | 2 |
| James Shields | LAD | sp | 26 | 3.14 | 16 | 10 | 0 | 32 | 32 | 4 | 2 | 229.0 | 203 | 89 | 80 | 42 | 204 | 27 | 16 |
| Scot Shields | SF | mr | 32 | 2.25 | 4 | 1 | 3 | 58 | 0 | 0 | 0 | 88.0 | 63 | 24 | 22 | 27 | 93 | 8 | 9 |
| Brian Shouse* | Sea | mr | 39 | 2.22 | 1 | 1 | 3 | 52 | 0 | 0 | 0 | 48.2 | 43 | 13 | 12 | 7 | 43 | 0 | 7 |
| Carlos Silva | Det | sp | 29 | 4.24 | 14 | 13 | 0 | 32 | 32 | 2 | 0 | 208.0 | 235 | 106 | 98 | 51 | 92 | 27 | 22 |
| Jason Simontacchi | NYM | sp | 34 | 5.60 | 4 | 6 | 0 | 16 | 16 | 0 | 0 | 82.0 | 110 | 57 | 51 | 23 | 70 | 15 | 7 |
| Andrew Sisco* | LAD | mr | 25 | 9.37 | 0 | 1 | 0 | 13 | 0 | 0 | 0 | 16.1 | 22 | 17 | 17 | 11 | 10 | 4 | 0 |
| Doug Slaten* | ChW | mr | 28 | 5.22 | 0 | 0 | 1 | 39 | 0 | 0 | 0 | 39.2 | 49 | 25 | 23 | 17 | 24 | 3 | 4 |
| Kevin Slowey | NYY | sp | 24 | 5.79 | 1 | 8 | 0 | 12 | 12 | 0 | 0 | 74.2 | 93 | 52 | 48 | 11 | 65 | 19 | 2 |
| Joe Smith | ChW | mr | 24 | 6.38 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 24.0 | 34 | 19 | 17 | 13 | 22 | 4 | 5 |
| John Smoltz | ChW | sp | 41 | 3.70 | 14 | 13 | 0 | 32 | 32 | 5 | 1 | 214.1 | 225 | 96 | 88 | 56 | 212 | 18 | 11 |
| Ian Snell | Was | sp | 26 | 3.40 | 19 | 7 | 0 | 32 | 32 | 3 | 2 | 227.1 | 188 | 88 | 86 | 62 | 188 | 17 | 21 |
| Kyle Snyder | Bos | mr | 30 | 4.15 | 5 | 0 | 1 | 46 | 0 | 0 | 0 | 80.1 | 54 | 39 | 37 | 43 | 52 | 7 | 2 |
| Andy Sonnanstine | Bos | sp | 25 | 4.00 | 9 | 5 | 0 | 25 | 25 | 0 | 0 | 148.1 | 162 | 71 | 66 | 36 | 93 | 13 | 19 |
| Joakim Soria | StL | cl | 24 | 1.71 | 5 | 4 | 33 | 55 | 0 | 0 | 0 | 68.1 | 50 | 17 | 13 | 12 | 80 | 2 | 1 |
| Rafael Soriano | Atl | mr | 28 | 2.32 | 7 | 4 | 1 | 88 | 0 | 0 | 0 | 112.1 | 83 | 32 | 29 | 22 | 101 | 15 | 6 |
| Jorge Sosa | Tor | mr | 31 | 5.55 | 9 | 8 | 0 | 26 | 26 | 1 | 1 | 146.0 | 168 | 101 | 90 | 63 | 104 | 24 | 12 |
| Jeremy Sowers* | Pit | sp | 25 | 4.67 | 3 | 2 | 0 | 12 | 12 | 0 | 0 | 69.1 | 74 | 36 | 36 | 19 | 33 | 9 | 3 |
| Justin Speier | Phi | mr | 34 | 3.45 | 1 | 6 | 22 | 51 | 0 | 0 | 0 | 62.2 | 50 | 24 | 24 | 13 | 70 | 12 | 4 |
| Ryan Speier | Min | mr | 28 | 2.70 | 1 | 1 | 0 | 15 | 0 | 0 | 0 | 30.0 | 23 | 11 | 9 | 7 | 19 | 0 | 2 |
| Russ Springer | Hou | mr | 39 | 1.89 | 14 | 5 | 38 | 79 | 0 | 0 | 0 | 104.2 | 84 | 24 | 22 | 35 | 103 | 6 | 10 |
| Chris Spurling | NYY | mr | 31 | 3.88 | 1 | 1 | 0 | 34 | 0 | 0 | 0 | 60.1 | 72 | 32 | 26 | 15 | 34 | 5 | 9 |
| Jason Stanford* | Was | mr | 31 | 4.00 | 0 | 1 | 0 | 3 | 2 | 0 | 0 | 9.0 | 13 | 4 | 4 | 2 | 6 | 0 | 1 |
| Mike Stanton* | Tor | mr | 41 | 6.22 | 3 | 2 | 0 | 37 | 0 | 0 | 0 | 63.2 | 92 | 47 | 44 | 25 | 47 | 9 | 6 |
| Tim Stauffer | KC | sp | 26 | 21.21 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 4.2 | 13 | 12 | 11 | 5 | 3 | 3 | 1 |
| Mitch Stetter* | Bos | mr | 27 | 54.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.1 | 1 | 2 | 2 | 1 | 1 | 0 | 0 |
| Huston Street | Det | cl | 24 | 1.58 | 6 | 4 | 32 | 53 | 0 | 0 | 0 | 74.0 | 47 | 16 | 13 | 16 | 94 | 6 | 5 |
| Jeff Suppan | Tex | sp | 33 | 6.08 | 8 | 20 | 0 | 34 | 34 | 2 | 1 | 219.0 | 301 | 159 | 148 | 72 | 117 | 19 | 23 |
| Jon Switzer* | Was | mr | 28 | 5.79 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 4.2 | 2 | 3 | 3 | 1 | 1 | 1 | 0 |
| Brian Tallet* | SF | mr | 30 | 1.73 | 6 | 2 | 9 | 52 | 0 | 0 | 0 | 73.0 | 58 | 17 | 14 | 21 | 56 | 1 | 5 |
| Taylor Tankersley* | Bal | mr | 25 | 5.91 | 2 | 6 | 0 | 48 | 0 | 0 | 0 | 53.1 | 66 | 37 | 35 | 33 | 58 | 4 | 7 |
| Jack Taschner* | Cin | mr | 30 | 4.69 | 1 | 7 | 2 | 57 | 0 | 0 | 0 | 71.0 | 65 | 40 | 37 | 53 | 69 | 9 | 4 |
| Jordan Tata | Cle | sp | 26 | 5.06 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.1 | 5 | 3 | 3 | 4 | 5 | 1 | 0 |
| Ty Taubenheim | Min | sp | 25 | 27.00 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 1.0 | 3 | 4 | 3 | 3 | 2 | 0 | 0 |
| Julian Tavarez | Phi | sp | 35 | 4.32 | 10 | 9 | 0 | 27 | 27 | 6 | 0 | 179.0 | 210 | 89 | 86 | 53 | 113 | 26 | 24 |
| Robinson Tejeda | Tex | sp | 26 | 6.46 | 8 | 7 | 0 | 18 | 18 | 0 | 0 | 94.2 | 102 | 70 | 68 | 61 | 83 | 19 | 3 |
| Joe Thatcher* | LAD | mr | 26 | 2.38 | 2 | 0 | 2 | 14 | 0 | 0 | 0 | 22.2 | 14 | 6 | 6 | 6 | 22 | 2 | 1 |
| Brad Thompson | LAD | mr | 26 | 7.26 | 2 | 4 | 0 | 6 | 6 | 0 | 0 | 31.0 | 39 | 26 | 25 | 13 | 12 | 7 | 5 |
| John Thomson | Col | sp | 34 | 5.85 | 1 | 1 | 0 | 3 | 3 | 1 | 0 | 20.0 | 27 | 13 | 13 | 6 | 12 | 0 | 3 |
| Matt Thornton* | Mil | mr | 31 | 3.16 | 3 | 3 | 0 | 69 | 0 | 0 | 0 | 91.0 | 90 | 35 | 32 | 29 | 84 | 4 | 8 |
| Erick Threets* | SF | mr | 26 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 2 | 0 | 0 | 5 | 3 | 0 | 0 |
| Mike Timlin | Mil | mr | 42 | 2.77 | 2 | 3 | 14 | 51 | 0 | 0 | 0 | 65.0 | 50 | 23 | 20 | 11 | 37 | 10 | 5 |
| Brett Tomko | Was | mr | 35 | 5.34 | 5 | 4 | 1 | 33 | 9 | 0 | 0 | 94.1 | 107 | 57 | 56 | 48 | 78 | 9 | 12 |
| Salomon Torres | Bos | mr | 36 | 3.55 | 3 | 3 | 1 | 49 | 0 | 0 | 0 | 66.0 | 58 | 32 | 26 | 31 | 54 | 7 | 9 |
| Josh Towers | Oak | sp | 31 | 4.21 | 7 | 7 | 0 | 19 | 18 | 3 | 0 | 128.1 | 135 | 63 | 60 | 28 | 94 | 17 | 13 |
| Billy Traber* | Tor | mr | 28 | 9.59 | 1 | 6 | 0 | 10 | 6 | 0 | 0 | 25.1 | 43 | 29 | 27 | 22 | 17 | 4 | 5 |
| Steve Trachsel | Phi | sp | 37 | 6.93 | 7 | 15 | 0 | 32 | 32 | 4 | 1 | 178.0 | 231 | 148 | 137 | 78 | 75 | 29 | 13 |
| Chin-hui Tsao | Pit | mr | 27 | 2.33 | 1 | 0 | 1 | 25 | 0 | 0 | 0 | 38.2 | 32 | 12 | 10 | 11 | 28 | 1 | 2 |
| Derrick Turnbow | ChC | mr | 30 | 3.05 | 6 | 6 | 50 | 72 | 0 | 0 | 0 | 79.2 | 51 | 29 | 27 | 60 | 103 | 6 | 7 |
| Jose Valverde | LAD | cl | 28 | 3.89 | 3 | 2 | 8 | 67 | 0 | 0 | 0 | 90.1 | 74 | 39 | 39 | 25 | 104 | 13 | 6 |
| John Van Benschoten | Pit | sp | 28 | 3.51 | 1 | 0 | 0 | 6 | 5 | 0 | 0 | 25.2 | 20 | 10 | 10 | 21 | 18 | 2 | 1 |
| Rick VandenHurk | ChW | sp | 23 | 8.10 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 3.1 | 5 | 4 | 3 | 2 | 4 | 1 | 0 |
| Claudio Vargas | Oak | sp | 30 | 6.24 | 7 | 12 | 0 | 29 | 28 | 1 | 0 | 153.0 | 184 | 118 | 106 | 67 | 118 | 23 | 9 |
| Javier Vazquez | Cle | sp | 31 | 3.06 | 21 | 6 | 0 | 32 | 32 | 4 | 1 | 226.1 | 186 | 89 | 77 | 48 | 239 | 38 | 12 |
| Jose Veras | Det | mr | 27 | 4.50 | 4 | 1 | 0 | 13 | 0 | 0 | 0 | 18.0 | 15 | 10 | 9 | 18 | 12 | 0 | 2 |
| Justin Verlander | Tor | sp | 25 | 4.47 | 10 | 18 | 0 | 35 | 35 | 5 | 2 | 235.2 | 210 | 125 | 117 | 87 | 202 | 37 | 9 |
| Carlos Villanueva | LAD | mr | 24 | 4.16 | 1 | 6 | 1 | 50 | 0 | 0 | 0 | 84.1 | 72 | 40 | 39 | 46 | 63 | 12 | 8 |
| Oscar Villarreal | Oak | mr | 26 | 4.52 | 4 | 4 | 1 | 59 | 0 | 0 | 0 | 127.1 | 123 | 72 | 64 | 50 | 93 | 8 | 4 |
| Ron Villone* | StL | mr | 38 | 2.47 | 4 | 1 | 1 | 38 | 0 | 0 | 0 | 43.2 | 29 | 13 | 12 | 6 | 33 | 3 | 2 |
| Luis Vizcaino | Hou | mr | 33 | 2.92 | 5 | 6 | 2 | 56 | 0 | 0 | 0 | 101.2 | 83 | 36 | 33 | 41 | 76 | 10 | 3 |
| Edinson Volquez | Ari | sp | 24 | 5.40 | 2 | 3 | 0 | 9 | 9 | 0 | 0 | 50.0 | 47 | 32 | 30 | 21 | 43 | 10 | 9 |
| Billy Wagner* | ChW | cl | 36 | 2.09 | 6 | 3 | 9 | 60 | 0 | 0 | 0 | 73.1 | 53 | 20 | 17 | 27 | 101 | 6 | 5 |
| Adam Wainwright | ChC | sp | 26 | 2.26 | 20 | 4 | 0 | 32 | 32 | 3 | 3 | 210.2 | 190 | 68 | 53 | 68 | 147 | 9 | 22 |
| Tim Wakefield | Det | sp | 41 | 4.48 | 19 | 6 | 0 | 32 | 32 | 3 | 1 | 186.2 | 195 | 110 | 93 | 65 | 129 | 28 | 16 |
| Jamie Walker* | Atl | mr | 36 | 2.77 | 6 | 1 | 3 | 67 | 0 | 0 | 0 | 81.1 | 69 | 29 | 25 | 16 | 64 | 6 | 3 |
| Tyler Walker | Pit | mr | 32 | 5.87 | 0 | 2 | 0 | 5 | 0 | 0 | 0 | 7.2 | 11 | 5 | 5 | 2 | 4 | 0 | 0 |
| Chien-Ming Wang | SD | sp | 28 | 2.52 | 21 | 4 | 0 | 32 | 32 | 5 | 4 | 221.1 | 179 | 63 | 62 | 47 | 104 | 6 | 21 |
| Jarrod Washburn* | NYM | sp | 33 | 4.70 | 9 | 13 | 0 | 32 | 32 | 4 | 2 | 199.0 | 220 | 107 | 104 | 75 | 110 | 22 | 20 |
| Ehren Wassermann | Col | mr | 27 | 4.71 | 2 | 6 | 0 | 33 | 0 | 0 | 0 | 42.0 | 52 | 23 | 22 | 10 | 30 | 4 | 3 |
| David Weathers | Cle | cl | 38 | 2.66 | 3 | 3 | 41 | 64 | 0 | 0 | 0 | 74.1 | 50 | 22 | 22 | 35 | 42 | 6 | 12 |
| Jeff Weaver | Col | sp | 31 | 5.51 | 9 | 13 | 0 | 31 | 31 | 3 | 0 | 196.0 | 248 | 126 | 120 | 38 | 109 | 35 | 15 |
| Jered Weaver | Cin | sp | 25 | 4.64 | 10 | 11 | 0 | 32 | 32 | 1 | 0 | 201.2 | 215 | 114 | 104 | 55 | 156 | 29 | 16 |
| Brandon Webb | Sea | sp | 29 | 2.98 | 19 | 7 | 0 | 32 | 32 | 7 | 3 | 226.2 | 199 | 83 | 75 | 68 | 199 | 11 | 17 |
| Todd Wellemeyer | Det | mr | 29 | 4.12 | 8 | 5 | 0 | 21 | 21 | 0 | 0 | 98.1 | 101 | 59 | 45 | 51 | 85 | 16 | 6 |
| David Wells* | NYY | sp | 45 | 5.94 | 6 | 20 | 0 | 32 | 32 | 0 | 0 | 171.1 | 241 | 130 | 113 | 57 | 109 | 17 | 22 |
| Kip Wells | Tex | sp | 31 | 6.99 | 7 | 14 | 0 | 30 | 30 | 2 | 0 | 166.0 | 205 | 145 | 129 | 84 | 133 | 21 | 9 |
| Jake Westbrook | Was | sp | 30 | 4.17 | 9 | 10 | 0 | 27 | 27 | 3 | 1 | 177.0 | 173 | 87 | 82 | 61 | 95 | 14 | 15 |
| Dan Wheeler | Cle | mr | 30 | 5.69 | 1 | 0 | 4 | 38 | 0 | 0 | 0 | 55.1 | 72 | 45 | 35 | 14 | 63 | 18 | 4 |
| Bob Wickman | Tex | cl | 39 | 5.52 | 3 | 1 | 3 | 27 | 0 | 0 | 0 | 29.1 | 36 | 19 | 18 | 17 | 23 | 3 | 4 |
| Todd Williams | Mil | mr | 37 | 5.79 | 1 | 4 | 0 | 20 | 0 | 0 | 0 | 28.0 | 41 | 19 | 18 | 9 | 19 | 3 | 5 |
| Woody Williams | KC | sp | 41 | 4.69 | 10 | 15 | 0 | 36 | 36 | 2 | 0 | 224.2 | 222 | 131 | 117 | 72 | 129 | 31 | 14 |
| Scott Williamson | Tam | mr | 32 | 2.84 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 6.1 | 5 | 2 | 2 | 6 | 6 | 1 | 1 |
| Dontrelle Willis* | SF | sp | 26 | 6.03 | 11 | 13 | 0 | 35 | 35 | 0 | 0 | 198.2 | 236 | 144 | 133 | 103 | 157 | 30 | 19 |
| Brian Wilson | Was | cl | 26 | 1.77 | 1 | 1 | 0 | 19 | 0 | 0 | 0 | 20.1 | 11 | 6 | 4 | 3 | 16 | 0 | 3 |
| C.J. Wilson* | Pit | mr | 27 | 3.93 | 3 | 8 | 4 | 70 | 0 | 0 | 0 | 94.0 | 85 | 43 | 41 | 41 | 71 | 7 | 17 |
| Matt Wise | SF | mr | 32 | 4.11 | 2 | 5 | 0 | 33 | 0 | 0 | 0 | 57.0 | 64 | 30 | 26 | 21 | 49 | 3 | 9 |
| Randy Wolf* | Bos | sp | 31 | 4.39 | 6 | 8 | 0 | 18 | 18 | 0 | 0 | 98.1 | 126 | 51 | 48 | 32 | 96 | 11 | 10 |
| Brian Wolfe | StL | mr | 27 | 1.71 | 1 | 1 | 3 | 41 | 0 | 0 | 0 | 63.0 | 47 | 13 | 12 | 22 | 34 | 2 | 5 |
| Kerry Wood | Mil | mr | 31 | 1.14 | 1 | 0 | 4 | 16 | 0 | 0 | 0 | 23.2 | 14 | 4 | 3 | 13 | 23 | 0 | 2 |
| Jamey Wright | ChC | mr | 33 | 3.47 | 4 | 4 | 0 | 15 | 10 | 0 | 0 | 72.2 | 64 | 31 | 28 | 25 | 32 | 8 | 12 |
| Michael Wuertz | NYY | mr | 29 | 3.91 | 3 | 5 | 1 | 52 | 0 | 0 | 0 | 66.2 | 66 | 29 | 29 | 30 | 78 | 9 | 2 |
| Tyler Yates | NYM | mr | 30 | 4.20 | 3 | 8 | 2 | 75 | 0 | 0 | 0 | 100.2 | 105 | 51 | 47 | 44 | 105 | 14 | 4 |
| Shane Youman* | StL | sp | 28 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Chris Young | Sea | sp | 29 | 4.33 | 15 | 9 | 0 | 31 | 31 | 0 | 0 | 181.0 | 149 | 96 | 87 | 89 | 172 | 18 | 12 |
| Carlos Zambrano | Det | sp | 27 | 4.46 | 17 | 7 | 0 | 35 | 35 | 1 | 0 | 224.0 | 194 | 119 | 111 | 128 | 197 | 24 | 25 |
| Victor Zambrano | Atl | mr | 32 | 9.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 3.0 | 4 | 3 | 3 | 1 | 3 | 2 | 0 |
| Barry Zito* | Ari | sp | 30 | 4.81 | 11 | 9 | 0 | 33 | 33 | 1 | 0 | 196.2 | 184 | 110 | 105 | 77 | 135 | 33 | 15 |
| Joel Zumaya | SD | mr | 23 | 7.71 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 4.2 | 6 | 4 | 4 | 2 | 4 | 0 | 1 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| David Aardsma | Min | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 9.0 | 9.0 | 99.0 | 3.00 |
| Jeremy Accardo | Ari | cl | 26 | 9 | 3 | 0 | 4 | 1 | 2 | 1 | 0 | 9.3 | 2.1 | 11.8 | 9.2 | 0.6 | 4.3 | 1.27 |
| Manny Acosta | StL | mr | 27 | 2 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 5.5 | 3.6 | 9.4 | 8.1 | 1.0 | 2.3 | 1.01 |
| Jeremy Affeldt* | Tam | mr | 29 | 9 | 3 | 3 | 6 | 8 | 1 | 4 | 2 | 6.5 | 5.0 | 12.0 | 7.9 | 0.1 | 1.6 | 1.27 |
| Jonathan Albaladejo | StL | mr | 25 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 5.9 | 3.0 | 9.5 | 7.2 | 1.3 | 2.4 | 0.99 |
| Matt Albers | Tam | sp | 25 | 13 | 2 | 0 | 6 | 6 | 0 | 0 | 4 | 11.6 | 3.9 | 16.0 | 6.9 | 1.3 | 1.8 | 1.72 |
| Greg Aquino | Cin | mr | 30 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 6.9 | 2.5 | 9.4 | 9.4 | 1.3 | 3.8 | 1.05 |
| Tony Armas | Col | mr | 30 | 7 | 2 | 2 | 12 | 3 | 0 | 2 | 4 | 9.6 | 4.0 | 14.5 | 7.6 | 1.7 | 1.9 | 1.51 |
| Bronson Arroyo | Atl | sp | 31 | 16 | 11 | 4 | 12 | 4 | 0 | 13 | 10 | 9.2 | 2.6 | 12.2 | 7.0 | 0.7 | 2.7 | 1.31 |
| Jose Ascanio | Ari | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 3.7 | 17.2 | 12.3 | 6.1 | 3.3 | 1.91 |
| Luis Ayala | LAD | mr | 30 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 8.3 | 3.4 | 12.0 | 5.8 | 0.6 | 1.7 | 1.30 |
| Brandon Backe | NYY | sp | 30 | 0 | 0 | 0 | 7 | 1 | 1 | 0 | 1 | 7.3 | 3.4 | 12.2 | 4.1 | 0.9 | 1.2 | 1.19 |
| Mike Bacsik* | Atl | sp | 30 | 2 | 3 | 4 | 6 | 6 | 0 | 6 | 7 | 10.8 | 2.4 | 13.6 | 3.2 | 1.4 | 1.3 | 1.47 |
| Cha Seung Baek | StL | sp | 28 | 5 | 1 | 0 | 3 | 3 | 0 | 4 | 8 | 11.3 | 2.1 | 13.7 | 6.2 | 0.9 | 2.9 | 1.49 |
| Danys Baez | Pit | mr | 30 | 6 | 0 | 6 | 11 | 1 | 0 | 0 | 6 | 10.4 | 3.9 | 15.4 | 5.0 | 1.4 | 1.3 | 1.59 |
| Homer Bailey | LAD | sp | 22 | 1 | 2 | 3 | 2 | 2 | 1 | 0 | 2 | 7.4 | 7.9 | 15.7 | 6.5 | 0.7 | 0.8 | 1.71 |
| Scott Baker | NYM | sp | 26 | 11 | 3 | 7 | 4 | 0 | 0 | 7 | 9 | 8.5 | 1.5 | 10.3 | 6.3 | 0.7 | 4.1 | 1.12 |
| John Bale* | LAD | mr | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 6.0 | 15.0 | 9.0 | 0.0 | 1.5 | 1.67 |
| Josh Banks | SF | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Brian Bannister | ChW | sp | 27 | 3 | 3 | 1 | 5 | 3 | 0 | 2 | 6 | 9.2 | 2.9 | 12.3 | 4.4 | 0.8 | 1.5 | 1.34 |
| Daniel Barone | Ari | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 3.0 | 9.0 | 0.0 | 6.0 | 0.0 | 1.00 |
| Miguel Batista | Was | sp | 37 | 7 | 7 | 9 | 12 | 10 | 3 | 8 | 6 | 9.0 | 4.2 | 13.8 | 7.2 | 0.7 | 1.7 | 1.46 |
| Yorman Bazardo | LAA | mr | 23 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 5.8 | 2.7 | 11.1 | 4.0 | 0.4 | 1.5 | 0.93 |
| Josh Beckett | Flo | sp | 28 | 18 | 7 | 2 | 13 | 3 | 0 | 6 | 6 | 8.4 | 1.8 | 10.7 | 8.6 | 0.9 | 4.8 | 1.13 |
| Erik Bedard* | Tor | sp | 29 | 7 | 2 | 1 | 6 | 1 | 0 | 4 | 2 | 7.7 | 2.9 | 10.8 | 11.2 | 0.8 | 3.9 | 1.18 |
| Joe Beimel* | ChC | mr | 31 | 2 | 1 | 4 | 1 | 4 | 1 | 1 | 3 | 8.9 | 2.6 | 11.6 | 5.0 | 0.4 | 1.9 | 1.27 |
| Matt Belisle | NYY | sp | 28 | 4 | 2 | 0 | 6 | 2 | 0 | 2 | 6 | 12.1 | 3.2 | 15.6 | 6.5 | 1.6 | 2.0 | 1.70 |
| Heath Bell | Ari | mr | 30 | 8 | 2 | 1 | 3 | 2 | 0 | 4 | 5 | 6.9 | 2.3 | 9.5 | 8.9 | 0.3 | 3.8 | 1.02 |
| Armando Benitez | Tam | mr | 35 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 7.0 | 2.2 | 9.2 | 10.3 | 1.1 | 4.8 | 1.02 |
| Jeff Bennett | Oak | sp | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 8.7 | 2.4 | 11.1 | 8.7 | 0.0 | 3.6 | 1.23 |
| Joaquin Benoit | Oak | mr | 30 | 5 | 0 | 1 | 2 | 2 | 0 | 4 | 6 | 7.4 | 2.5 | 10.1 | 9.1 | 0.5 | 3.6 | 1.10 |
| Jason Bergmann | Cin | sp | 26 | 11 | 1 | 6 | 2 | 3 | 0 | 4 | 3 | 7.9 | 4.2 | 12.3 | 7.6 | 1.5 | 1.8 | 1.35 |
| Rafael Betancourt | ChW | mr | 33 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.1 | 0.3 | 5.4 | 9.3 | 0.5 | 36.7 | 0.60 |
| Chad Billingsley | Ari | mr | 23 | 9 | 5 | 2 | 3 | 4 | 0 | 6 | 7 | 9.2 | 4.4 | 13.8 | 7.9 | 1.3 | 1.8 | 1.51 |
| Kurt Birkins* | LAA | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.4 | 3.9 | 19.3 | 7.7 | 0.0 | 2.0 | 2.14 |
| Travis Blackley* | Cin | sp | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 11.3 | 6.9 | 18.2 | 3.1 | 2.5 | 0.5 | 2.02 |
| Joe Blanton | NYY | sp | 27 | 9 | 4 | 0 | 8 | 2 | 3 | 2 | 9 | 10.9 | 1.7 | 13.0 | 6.2 | 0.7 | 3.6 | 1.40 |
| Jeremy Bonderman | LAD | sp | 25 | 18 | 10 | 3 | 7 | 10 | 0 | 9 | 3 | 10.9 | 1.9 | 13.2 | 7.5 | 1.5 | 3.9 | 1.43 |
| Boof Bonser | LAA | sp | 26 | 0 | 0 | 6 | 1 | 2 | 0 | 0 | 3 | 8.6 | 2.6 | 11.3 | 6.7 | 1.0 | 2.5 | 1.24 |
| Chris Booker | Phi | mr | 31 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 23.1 | 17.4 | 40.5 | 1.9 | 1.9 | 0.1 | 4.50 |
| Chris Bootcheck | Min | mr | 29 | 4 | 2 | 0 | 4 | 5 | 3 | 1 | 2 | 12.3 | 2.4 | 15.8 | 7.8 | 1.6 | 3.2 | 1.63 |
| Dave Borkowski | Oak | mr | 31 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 9.6 | 4.2 | 14.3 | 7.0 | 1.2 | 1.7 | 1.54 |
| Joe Borowski | Sea | cl | 37 | 4 | 2 | 0 | 3 | 2 | 0 | 1 | 4 | 9.9 | 1.4 | 11.6 | 7.8 | 0.9 | 5.7 | 1.25 |
| Micah Bowie* | SD | mr | 33 | 3 | 1 | 2 | 1 | 0 | 1 | 3 | 0 | 7.8 | 5.2 | 13.2 | 6.5 | 0.4 | 1.3 | 1.45 |
| Blaine Boyer | Oak | mr | 26 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 9.6 | 0.0 | 9.6 | 1.9 | 0.0 | 99.0 | 1.07 |
| Dallas Braden* | Atl | sp | 24 | 4 | 2 | 0 | 3 | 2 | 0 | 3 | 1 | 10.6 | 2.7 | 13.7 | 6.8 | 2.1 | 2.5 | 1.48 |
| Chad Bradford | Ari | mr | 33 | 3 | 2 | 5 | 8 | 0 | 0 | 3 | 4 | 11.9 | 2.8 | 15.7 | 5.0 | 0.5 | 1.8 | 1.64 |
| Ryan Braun | NYY | mr | 27 | 2 | 0 | 0 | 2 | 5 | 0 | 1 | 2 | 11.5 | 4.7 | 16.6 | 6.2 | 1.7 | 1.3 | 1.80 |
| Chris Britton | Cin | mr | 25 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 3.6 | 3.6 | 7.1 | 2.4 | 0.4 | 0.7 | 0.79 |
| Lance Broadway | Flo | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.6 | 4.8 | 12.5 | 8.3 | 0.0 | 1.7 | 1.38 |
| Doug Brocail | Was | mr | 41 | 4 | 1 | 5 | 2 | 1 | 0 | 3 | 2 | 6.7 | 2.1 | 9.0 | 4.3 | 0.7 | 2.0 | 0.98 |
| Andrew Brown | Tam | mr | 27 | 9 | 1 | 0 | 3 | 9 | 0 | 2 | 0 | 7.1 | 2.9 | 10.4 | 10.0 | 0.6 | 3.5 | 1.11 |
| Jonathan Broxton | Flo | mr | 24 | 6 | 1 | 0 | 0 | 3 | 0 | 1 | 4 | 7.0 | 2.3 | 9.3 | 11.6 | 0.6 | 5.1 | 1.03 |
| Brian Bruney | Sea | mr | 26 | 1 | 0 | 2 | 4 | 4 | 0 | 2 | 5 | 8.4 | 5.8 | 14.9 | 8.4 | 0.8 | 1.5 | 1.58 |
| Clay Buchholz | Det | sp | 23 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.4 | 6.0 | 12.1 | 7.9 | 0.3 | 1.3 | 1.27 |
| Taylor Buchholz | Min | mr | 26 | 7 | 2 | 0 | 1 | 3 | 1 | 1 | 3 | 9.7 | 1.9 | 11.7 | 6.6 | 0.6 | 3.4 | 1.30 |
| Billy Buckner | Tex | sp | 24 | 1 | 0 | 0 | 1 | 1 | 0 | 2 | 1 | 8.3 | 4.0 | 12.5 | 4.7 | 1.8 | 1.2 | 1.36 |
| Mark Buehrle* | LAA | sp | 29 | 3 | 0 | 1 | 6 | 1 | 0 | 2 | 6 | 10.7 | 2.4 | 13.4 | 5.3 | 1.2 | 2.2 | 1.45 |
| Jason Bulger | ChC | mr | 29 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 6.1 | 3.1 | 9.2 | 5.5 | 0.0 | 1.8 | 1.02 |
| Bryan Bullington | Pit | sp | 27 | 6 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 13.0 | 3.4 | 16.4 | 2.7 | 1.7 | 0.8 | 1.82 |
| Ambiorix Burgos | Bos | mr | 24 | 1 | 0 | 3 | 0 | 1 | 0 | 1 | 2 | 3.2 | 4.5 | 7.7 | 9.2 | 0.5 | 2.1 | 0.85 |
| A.J. Burnett | Col | sp | 31 | 20 | 5 | 0 | 11 | 2 | 0 | 8 | 3 | 7.3 | 2.8 | 10.6 | 10.2 | 0.7 | 3.7 | 1.13 |
| Brian Burres* | Was | mr | 27 | 9 | 2 | 11 | 7 | 5 | 0 | 7 | 5 | 8.5 | 5.3 | 14.3 | 6.6 | 0.9 | 1.2 | 1.54 |
| Jared Burton | Bos | mr | 27 | 12 | 1 | 0 | 3 | 3 | 3 | 1 | 6 | 6.5 | 4.4 | 11.2 | 7.2 | 0.4 | 1.7 | 1.21 |
| Dave Bush | KC | sp | 28 | 18 | 2 | 2 | 14 | 2 | 0 | 1 | 7 | 10.2 | 3.6 | 14.3 | 7.1 | 0.8 | 2.0 | 1.52 |
| Paul Byrd | Pit | sp | 37 | 6 | 1 | 2 | 7 | 3 | 0 | 10 | 5 | 10.5 | 1.1 | 12.0 | 5.6 | 1.4 | 4.9 | 1.29 |
| Tim Byrdak* | Col | mr | 34 | 3 | 5 | 4 | 2 | 2 | 0 | 1 | 1 | 7.2 | 3.4 | 10.9 | 8.9 | 0.8 | 2.6 | 1.18 |
| Daniel Cabrera | Mil | sp | 27 | 13 | 6 | 10 | 16 | 6 | 4 | 5 | 10 | 9.3 | 3.8 | 13.8 | 7.9 | 1.2 | 2.1 | 1.46 |
| Fernando Cabrera | StL | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 4.5 | 11.3 | 13.5 | 0.0 | 3.0 | 1.25 |
| Matt Cain | SF | sp | 23 | 19 | 4 | 3 | 9 | 17 | 0 | 5 | 7 | 9.2 | 4.1 | 13.7 | 8.8 | 0.8 | 2.2 | 1.47 |
| Kiko Calero | ChW | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 9.3 | 3.1 | 12.3 | 6.9 | 1.5 | 2.3 | 1.37 |
| Kevin Cameron | Det | mr | 28 | 18 | 0 | 1 | 5 | 2 | 1 | 3 | 9 | 10.8 | 6.5 | 17.8 | 9.7 | 0.4 | 1.5 | 1.92 |
| Shawn Camp | Hou | mr | 32 | 0 | 1 | 0 | 3 | 2 | 0 | 3 | 2 | 18.6 | 2.8 | 21.8 | 9.1 | 1.9 | 3.2 | 2.38 |
| Jose Capellan | Hou | mr | 27 | 2 | 0 | 3 | 0 | 4 | 0 | 1 | 2 | 7.4 | 3.0 | 10.4 | 5.0 | 0.7 | 1.7 | 1.16 |
| Matt Capps | Was | mr | 24 | 4 | 0 | 7 | 3 | 1 | 0 | 0 | 4 | 7.1 | 2.2 | 9.8 | 7.3 | 0.6 | 3.3 | 1.04 |
| Chris Capuano* | NYY | sp | 29 | 6 | 4 | 2 | 4 | 13 | 0 | 2 | 4 | 11.0 | 3.7 | 15.0 | 8.3 | 1.0 | 2.2 | 1.64 |
| Buddy Carlyle | Atl | sp | 30 | 5 | 4 | 7 | 4 | 1 | 0 | 2 | 2 | 9.2 | 3.0 | 12.5 | 6.0 | 1.1 | 2.0 | 1.36 |
| Fausto Carmona | SD | sp | 27 | 8 | 5 | 8 | 16 | 10 | 1 | 8 | 2 | 7.9 | 2.3 | 10.9 | 5.4 | 0.6 | 2.3 | 1.13 |
| Chris Carpenter | Min | sp | 33 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 11.4 | 4.2 | 16.6 | 5.2 | 0.0 | 1.3 | 1.73 |
| Marcos Carvajal | Oak | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 27.0 | 0.0 | 99.0 | 3.00 |
| Santiago Casilla | Col | mr | 27 | 12 | 2 | 3 | 2 | 9 | 0 | 2 | 1 | 8.6 | 4.4 | 13.3 | 9.4 | 1.9 | 2.2 | 1.45 |
| Jack Cassel | Tex | sp | 27 | 2 | 0 | 0 | 1 | 3 | 0 | 0 | 2 | 12.9 | 5.3 | 18.5 | 4.7 | 0.3 | 0.9 | 2.02 |
| Fabio Castro* | ChW | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.3 | 20.3 | 31.5 | 4.5 | 0.0 | 0.2 | 3.50 |
| Gustavo Chacin* | LAD | sp | 27 | 0 | 0 | 0 | 4 | 1 | 0 | 2 | 3 | 10.0 | 1.0 | 12.0 | 4.3 | 1.5 | 4.3 | 1.22 |
| Shawn Chacon | Cin | mr | 30 | 9 | 3 | 13 | 10 | 2 | 0 | 4 | 6 | 9.1 | 5.5 | 15.5 | 7.2 | 1.3 | 1.3 | 1.62 |
| Joba Chamberlain | Oak | mr | 22 | 1 | 1 | 0 | 2 | 2 | 1 | 0 | 2 | 5.9 | 4.5 | 11.0 | 12.4 | 0.8 | 2.8 | 1.16 |
| Rocky Cherry | Was | mr | 28 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 6.4 | 2.8 | 10.1 | 6.9 | 0.8 | 2.4 | 1.03 |
| Matt Chico* | Det | sp | 25 | 16 | 1 | 2 | 4 | 6 | 0 | 2 | 14 | 10.7 | 4.4 | 15.3 | 5.7 | 1.1 | 1.3 | 1.68 |
| Vinnie Chulk | KC | mr | 29 | 2 | 3 | 5 | 3 | 4 | 0 | 1 | 7 | 8.0 | 3.2 | 11.5 | 7.7 | 0.5 | 2.4 | 1.26 |
| Roger Clemens | SD | sp | 45 | 13 | 2 | 2 | 7 | 11 | 0 | 4 | 5 | 9.1 | 2.6 | 12.2 | 5.8 | 0.8 | 2.3 | 1.30 |
| Tyler Clippard | Ari | sp | 23 | 2 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 7.4 | 3.0 | 11.0 | 5.5 | 1.7 | 1.8 | 1.16 |
| Todd Coffey | SF | mr | 27 | 4 | 1 | 2 | 4 | 8 | 0 | 4 | 2 | 15.1 | 3.9 | 19.9 | 6.0 | 1.3 | 1.6 | 2.11 |
| Jesus Colome | Pit | mr | 30 | 6 | 3 | 6 | 5 | 10 | 0 | 4 | 5 | 11.6 | 4.1 | 16.2 | 6.4 | 0.8 | 1.5 | 1.75 |
| Bartolo Colon | Tor | sp | 35 | 2 | 1 | 2 | 14 | 1 | 0 | 2 | 5 | 13.1 | 2.9 | 16.7 | 7.8 | 1.7 | 2.7 | 1.77 |
| Jose Contreras | Bal | sp | 36 | 24 | 1 | 0 | 9 | 7 | 0 | 2 | 11 | 11.4 | 3.8 | 15.7 | 5.7 | 1.3 | 1.5 | 1.69 |
| Aaron Cook | Atl | sp | 29 | 13 | 9 | 0 | 8 | 0 | 0 | 9 | 4 | 9.4 | 2.3 | 12.1 | 3.1 | 0.8 | 1.4 | 1.30 |
| Chad Cordero | SF | cl | 26 | 3 | 0 | 2 | 1 | 4 | 3 | 4 | 3 | 9.2 | 3.6 | 12.9 | 8.5 | 0.8 | 2.4 | 1.42 |
| Francisco Cordero | Oak | cl | 33 | 3 | 2 | 2 | 1 | 4 | 0 | 0 | 1 | 7.2 | 3.7 | 11.0 | 12.0 | 0.3 | 3.3 | 1.21 |
| Bryan Corey | Tam | mr | 34 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 9.4 | 6.8 | 16.2 | 6.8 | 0.7 | 1.0 | 1.80 |
| Lance Cormier | Flo | sp | 27 | 3 | 1 | 0 | 1 | 5 | 0 | 1 | 0 | 11.6 | 4.5 | 16.3 | 5.7 | 2.3 | 1.3 | 1.79 |
| Manny Corpas | Sea | mr | 25 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.5 | 1.7 | 7.5 | 6.6 | 0.5 | 3.9 | 0.80 |
| Kevin Correia | LAA | mr | 27 | 2 | 1 | 0 | 0 | 1 | 1 | 2 | 4 | 7.3 | 2.9 | 10.2 | 6.6 | 0.7 | 2.3 | 1.13 |
| Neal Cotts* | Tam | mr | 28 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 3 | 7.2 | 4.3 | 11.8 | 8.6 | 0.6 | 2.0 | 1.28 |
| Jon Coutlangus* | Det | mr | 27 | 3 | 1 | 1 | 2 | 12 | 0 | 1 | 0 | 10.9 | 7.6 | 18.9 | 9.3 | 1.2 | 1.2 | 2.06 |
| Juan Cruz | Det | mr | 29 | 5 | 1 | 8 | 3 | 3 | 3 | 2 | 7 | 5.8 | 5.2 | 11.3 | 12.4 | 0.6 | 2.4 | 1.22 |
| John Danks* | Col | sp | 23 | 9 | 7 | 2 | 5 | 0 | 0 | 9 | 1 | 11.8 | 3.3 | 15.3 | 7.0 | 2.1 | 2.2 | 1.67 |
| Kyle Davies | Cin | sp | 24 | 14 | 3 | 1 | 4 | 7 | 0 | 7 | 3 | 11.0 | 4.2 | 15.6 | 6.7 | 2.2 | 1.6 | 1.70 |
| Doug Davis* | StL | sp | 32 | 6 | 4 | 2 | 5 | 13 | 1 | 16 | 6 | 9.5 | 4.0 | 13.7 | 7.0 | 0.7 | 1.8 | 1.50 |
| Jorge De La Rosa* | Bos | sp | 27 | 13 | 1 | 2 | 2 | 4 | 2 | 0 | 4 | 10.9 | 3.4 | 14.5 | 5.8 | 1.0 | 1.7 | 1.59 |
| Manny Delcarmen | Cle | mr | 26 | 2 | 0 | 1 | 2 | 3 | 0 | 3 | 2 | 7.3 | 3.5 | 11.1 | 8.2 | 1.0 | 2.3 | 1.20 |
| Ryan Dempster | Min | cl | 31 | 4 | 2 | 2 | 4 | 0 | 1 | 2 | 1 | 6.5 | 2.8 | 9.8 | 6.6 | 0.9 | 2.3 | 1.04 |
| Julio DePaula | NYY | mr | 25 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 1 | 14.8 | 4.0 | 20.7 | 2.3 | 2.3 | 0.6 | 2.10 |
| Matt DeSalvo | Phi | sp | 27 | 4 | 2 | 3 | 3 | 6 | 0 | 0 | 2 | 15.2 | 5.9 | 21.8 | 2.5 | 0.7 | 0.4 | 2.35 |
| Ross Detwiler* | Tex | mr | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 0.0 | 4.5 | 0.0 | 0.0 | 0.0 | 0.50 |
| Joey Devine | Hou | mr | 24 | 1 | 0 | 1 | 1 | 1 | 0 | 2 | 0 | 14.9 | 11.4 | 27.0 | 9.2 | 1.4 | 0.8 | 2.92 |
| Lenny DiNardo* | Tam | sp | 28 | 3 | 2 | 6 | 6 | 0 | 0 | 2 | 4 | 9.4 | 3.7 | 13.5 | 4.8 | 0.9 | 1.3 | 1.46 |
| Scott Dohmann | KC | mr | 30 | 5 | 2 | 0 | 4 | 0 | 0 | 3 | 3 | 6.4 | 3.8 | 10.7 | 7.7 | 0.7 | 2.0 | 1.13 |
| Brendan Donnelly | Tor | mr | 36 | 2 | 0 | 0 | 6 | 10 | 0 | 2 | 3 | 7.0 | 2.8 | 10.7 | 5.0 | 0.6 | 1.8 | 1.09 |
| Octavio Dotel | Ari | cl | 34 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 15.8 | 0.0 | 15.8 | 11.3 | 4.5 | 99.0 | 1.75 |
| Scott Downs* | LAA | mr | 32 | 0 | 2 | 2 | 1 | 4 | 2 | 0 | 4 | 8.5 | 3.6 | 12.3 | 9.3 | 0.3 | 2.6 | 1.35 |
| Brandon Duckworth | Was | mr | 32 | 1 | 0 | 3 | 0 | 5 | 0 | 3 | 0 | 7.0 | 4.7 | 11.7 | 5.2 | 0.3 | 1.1 | 1.30 |
| Zach Duke* | Oak | sp | 25 | 6 | 2 | 2 | 5 | 0 | 0 | 3 | 5 | 14.2 | 2.9 | 17.5 | 3.8 | 1.1 | 1.3 | 1.90 |
| Phil Dumatrait* | NYM | sp | 26 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 19.1 | 12.4 | 31.5 | 3.4 | 0.0 | 0.3 | 3.50 |
| Chad Durbin | Bos | sp | 30 | 7 | 1 | 1 | 12 | 1 | 0 | 5 | 5 | 9.2 | 4.1 | 14.1 | 5.2 | 1.1 | 1.3 | 1.48 |
| J.D. Durbin | SF | sp | 26 | 4 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 15.0 | 7.4 | 22.7 | 4.6 | 0.3 | 0.6 | 2.49 |
| Adam Eaton | Bal | sp | 30 | 1 | 1 | 0 | 7 | 3 | 0 | 1 | 7 | 11.5 | 5.7 | 17.9 | 5.0 | 1.8 | 0.9 | 1.92 |
| Scott Elarton | Mil | sp | 32 | 5 | 0 | 3 | 6 | 3 | 0 | 0 | 3 | 13.6 | 4.6 | 19.8 | 3.1 | 2.6 | 0.7 | 2.03 |
| Alan Embree* | Bos | cl | 38 | 7 | 1 | 1 | 1 | 0 | 0 | 2 | 2 | 10.6 | 1.9 | 12.5 | 6.9 | 1.1 | 3.7 | 1.38 |
| Kelvim Escobar | Bal | sp | 32 | 15 | 4 | 0 | 1 | 7 | 0 | 4 | 2 | 6.3 | 2.8 | 9.1 | 7.0 | 0.3 | 2.5 | 1.01 |
| Dana Eveland* | KC | mr | 24 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 18.0 | 9.0 | 27.0 | 4.5 | 1.5 | 0.5 | 3.00 |
| Scott Eyre* | Was | mr | 36 | 4 | 1 | 8 | 1 | 2 | 0 | 5 | 2 | 9.2 | 7.1 | 16.5 | 6.7 | 0.4 | 0.9 | 1.81 |
| Kyle Farnsworth | Cle | mr | 32 | 5 | 1 | 1 | 4 | 5 | 1 | 0 | 11 | 8.9 | 3.0 | 12.3 | 6.5 | 1.3 | 2.2 | 1.32 |
| Scott Feldman | Tex | mr | 25 | 6 | 2 | 2 | 6 | 5 | 1 | 2 | 3 | 9.2 | 7.4 | 17.4 | 6.4 | 0.7 | 0.9 | 1.84 |
| Pedro Feliciano* | Oak | mr | 31 | 5 | 1 | 2 | 5 | 1 | 2 | 2 | 3 | 8.7 | 4.8 | 14.0 | 8.3 | 0.6 | 1.7 | 1.50 |
| Randy Flores* | Ari | mr | 32 | 1 | 2 | 1 | 1 | 1 | 0 | 5 | 1 | 11.6 | 2.3 | 14.1 | 6.1 | 0.5 | 2.7 | 1.54 |
| Ron Flores* | NYY | mr | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.0 | 0.0 | 9.0 | 13.5 | 0.0 | 99.0 | 1.00 |
| Gavin Floyd | LAA | sp | 25 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 10.2 | 3.1 | 14.2 | 8.0 | 2.7 | 2.6 | 1.48 |
| Josh Fogg | Ari | sp | 31 | 5 | 3 | 3 | 5 | 2 | 0 | 4 | 2 | 10.7 | 2.7 | 13.9 | 6.0 | 1.3 | 2.3 | 1.49 |
| Casey Fossum* | Pit | mr | 30 | 10 | 1 | 2 | 5 | 5 | 0 | 1 | 3 | 15.0 | 3.1 | 18.6 | 5.8 | 1.4 | 1.9 | 2.00 |
| Jeff Francis* | LAD | sp | 27 | 16 | 8 | 3 | 6 | 0 | 3 | 13 | 11 | 9.8 | 2.7 | 12.8 | 6.7 | 0.5 | 2.5 | 1.39 |
| Frank Francisco | Min | mr | 28 | 1 | 2 | 0 | 2 | 12 | 0 | 0 | 2 | 8.2 | 4.1 | 12.6 | 6.6 | 0.3 | 1.6 | 1.36 |
| Ryan Franklin | ChC | mr | 35 | 2 | 4 | 2 | 4 | 1 | 0 | 2 | 1 | 6.7 | 1.0 | 8.1 | 5.4 | 1.0 | 5.6 | 0.85 |
| Jason Frasor | StL | mr | 30 | 4 | 1 | 4 | 1 | 1 | 2 | 3 | 2 | 7.0 | 3.0 | 10.1 | 9.2 | 0.1 | 3.1 | 1.11 |
| Brian Fuentes* | Tor | cl | 32 | 0 | 2 | 2 | 5 | 3 | 0 | 2 | 4 | 7.9 | 4.5 | 13.0 | 9.4 | 0.5 | 2.1 | 1.37 |
| Aaron Fultz* | Tex | mr | 34 | 2 | 1 | 3 | 2 | 4 | 0 | 2 | 5 | 9.2 | 5.4 | 14.8 | 8.2 | 0.6 | 1.5 | 1.62 |
| Kason Gabbard* | LAD | sp | 26 | 10 | 3 | 2 | 12 | 3 | 0 | 3 | 0 | 7.0 | 4.1 | 12.1 | 6.4 | 1.1 | 1.6 | 1.23 |
| Eric Gagne | NYM | cl | 32 | 4 | 0 | 6 | 2 | 2 | 0 | 4 | 2 | 8.0 | 3.7 | 12.0 | 7.7 | 0.6 | 2.1 | 1.31 |
| Armando Galarraga | KC | mr | 26 | 8 | 0 | 5 | 2 | 1 | 0 | 0 | 2 | 7.9 | 6.2 | 14.3 | 6.3 | 1.8 | 1.0 | 1.57 |
| Sean Gallagher | Tex | mr | 22 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 8.1 | 16.2 | 29.7 | 2.7 | 0.0 | 0.2 | 2.70 |
| Yovani Gallardo | StL | sp | 22 | 9 | 3 | 1 | 5 | 4 | 0 | 6 | 5 | 9.1 | 2.6 | 12.1 | 8.0 | 1.2 | 3.0 | 1.31 |
| Freddy Garcia | Det | sp | 32 | 0 | 0 | 0 | 4 | 2 | 0 | 0 | 0 | 9.0 | 3.0 | 14.4 | 8.4 | 2.4 | 2.8 | 1.33 |
| Harvey Garcia | SF | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 27.0 | 9.0 | 99.0 | 1.00 |
| Lee Gardner | Bos | mr | 33 | 2 | 2 | 1 | 9 | 0 | 0 | 3 | 5 | 8.5 | 2.1 | 11.4 | 5.1 | 0.3 | 2.5 | 1.18 |
| Jon Garland | Pit | sp | 28 | 6 | 3 | 1 | 7 | 2 | 0 | 5 | 7 | 9.0 | 2.1 | 11.4 | 3.9 | 0.6 | 1.8 | 1.24 |
| Matt Garza | Oak | sp | 24 | 1 | 2 | 1 | 6 | 1 | 0 | 0 | 3 | 9.3 | 3.0 | 12.8 | 8.7 | 0.9 | 2.9 | 1.36 |
| Chad Gaudin | NYM | sp | 25 | 15 | 4 | 3 | 7 | 4 | 1 | 10 | 3 | 8.8 | 4.5 | 13.7 | 6.9 | 1.0 | 1.5 | 1.48 |
| Geoff Geary | Flo | mr | 31 | 3 | 1 | 0 | 15 | 4 | 0 | 4 | 4 | 10.8 | 3.2 | 15.4 | 5.7 | 0.5 | 1.8 | 1.56 |
| Justin Germano | StL | sp | 25 | 22 | 6 | 3 | 8 | 0 | 0 | 7 | 3 | 8.0 | 2.2 | 10.5 | 5.3 | 0.9 | 2.5 | 1.12 |
| Tom Glavine* | ChC | sp | 42 | 10 | 3 | 2 | 6 | 3 | 0 | 8 | 5 | 12.1 | 3.3 | 15.8 | 4.1 | 1.5 | 1.2 | 1.71 |
| Gary Glover | Mil | mr | 31 | 3 | 2 | 1 | 1 | 2 | 0 | 3 | 6 | 9.7 | 2.7 | 12.5 | 7.8 | 1.4 | 2.9 | 1.37 |
| Jimmy Gobble* | Flo | mr | 26 | 0 | 1 | 3 | 1 | 5 | 1 | 1 | 0 | 14.2 | 3.3 | 17.8 | 7.8 | 1.7 | 2.4 | 1.95 |
| Edgar Gonzalez | Col | mr | 25 | 1 | 2 | 10 | 7 | 1 | 3 | 3 | 3 | 9.7 | 3.0 | 13.2 | 5.6 | 1.3 | 1.9 | 1.41 |
| Mike Gonzalez* | Atl | mr | 30 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 11.3 | 8.7 | 20.0 | 7.0 | 0.0 | 0.8 | 2.23 |
| Tom Gordon | Phi | mr | 40 | 3 | 0 | 8 | 6 | 2 | 0 | 4 | 4 | 10.3 | 4.8 | 15.8 | 7.2 | 1.9 | 1.5 | 1.68 |
| Tom Gorzelanny* | Pit | sp | 25 | 8 | 4 | 6 | 8 | 5 | 0 | 8 | 12 | 10.2 | 3.2 | 13.8 | 6.4 | 0.9 | 2.0 | 1.49 |
| John Grabow* | Bal | mr | 29 | 5 | 3 | 3 | 2 | 4 | 0 | 0 | 1 | 10.1 | 4.4 | 14.7 | 7.3 | 0.7 | 1.7 | 1.61 |
| Sean Green | Min | mr | 29 | 1 | 1 | 2 | 2 | 2 | 0 | 0 | 2 | 10.8 | 4.0 | 15.2 | 7.8 | 0.4 | 2.0 | 1.65 |
| Kevin Gregg | Det | cl | 30 | 3 | 3 | 0 | 3 | 7 | 0 | 0 | 7 | 5.9 | 4.5 | 10.7 | 10.5 | 0.7 | 2.4 | 1.16 |
| Zack Greinke | LAA | mr | 24 | 6 | 2 | 1 | 4 | 4 | 0 | 2 | 7 | 9.4 | 2.2 | 11.8 | 8.6 | 1.0 | 3.9 | 1.29 |
| Jason Grilli | Phi | mr | 31 | 4 | 2 | 1 | 4 | 4 | 0 | 2 | 5 | 12.1 | 3.4 | 16.0 | 8.3 | 1.0 | 2.4 | 1.72 |
| Eddie Guardado* | Mil | mr | 37 | 2 | 0 | 2 | 3 | 6 | 0 | 1 | 4 | 14.8 | 3.6 | 19.8 | 6.8 | 1.3 | 1.9 | 2.05 |
| Matt Guerrier | Sea | mr | 29 | 4 | 1 | 3 | 8 | 4 | 0 | 1 | 1 | 8.9 | 2.3 | 12.2 | 7.5 | 1.0 | 3.2 | 1.25 |
| Jeremy Guthrie | Min | sp | 29 | 2 | 2 | 2 | 2 | 7 | 0 | 1 | 3 | 7.8 | 2.8 | 10.7 | 6.4 | 1.0 | 2.3 | 1.17 |
| Juan Gutierrez | SD | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.8 | 1.3 | 10.0 | 6.3 | 1.3 | 5.0 | 1.12 |
| Roy Halladay | Hou | sp | 31 | 10 | 5 | 3 | 3 | 3 | 0 | 10 | 3 | 9.1 | 1.7 | 11.0 | 5.3 | 0.6 | 3.0 | 1.21 |
| Cole Hamels* | Flo | sp | 24 | 17 | 4 | 2 | 12 | 6 | 0 | 5 | 5 | 7.6 | 2.7 | 10.9 | 9.1 | 0.9 | 3.3 | 1.15 |
| Jason Hammel | Sea | sp | 25 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 10.3 | 3.0 | 13.3 | 4.9 | 1.9 | 1.6 | 1.48 |
| Justin Hampson* | SD | mr | 28 | 3 | 3 | 3 | 1 | 0 | 0 | 3 | 1 | 9.0 | 2.3 | 11.5 | 6.2 | 0.7 | 2.7 | 1.25 |
| Joel Hanrahan | NYM | sp | 26 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 2 | 18.4 | 7.2 | 25.7 | 4.0 | 2.6 | 0.5 | 2.85 |
| Aaron Harang | Cle | sp | 30 | 16 | 6 | 0 | 10 | 9 | 1 | 1 | 9 | 8.7 | 2.7 | 11.8 | 8.4 | 0.9 | 3.2 | 1.27 |
| Rich Harden | Col | sp | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.9 | 2.3 | 7.2 | 12.5 | 1.1 | 5.5 | 0.80 |
| Dan Haren | LAA | sp | 27 | 9 | 1 | 0 | 8 | 9 | 0 | 6 | 5 | 7.7 | 2.0 | 10.0 | 7.5 | 1.0 | 3.7 | 1.08 |
| Kevin Hart | LAA | mr | 25 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 2.4 | 4.8 | 7.2 | 8.4 | 0.0 | 1.8 | 0.80 |
| LaTroy Hawkins | Tex | mr | 35 | 2 | 0 | 1 | 1 | 2 | 0 | 2 | 5 | 9.4 | 2.8 | 12.3 | 5.2 | 0.8 | 1.9 | 1.35 |
| Aaron Heilman | Hou | mr | 29 | 8 | 2 | 1 | 6 | 4 | 0 | 1 | 3 | 7.7 | 1.8 | 10.0 | 7.5 | 0.6 | 4.2 | 1.06 |
| Mark Hendrickson* | Sea | mr | 34 | 6 | 1 | 1 | 3 | 2 | 0 | 1 | 3 | 9.3 | 2.5 | 12.0 | 7.2 | 1.0 | 2.9 | 1.31 |
| Sean Henn* | Flo | mr | 27 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.9 | 0.0 | 3.9 | 3.9 | 0.0 | 99.0 | 0.43 |
| Brad Hennessey | Flo | cl | 28 | 5 | 0 | 4 | 4 | 1 | 0 | 0 | 2 | 9.9 | 4.1 | 14.6 | 6.1 | 1.3 | 1.5 | 1.56 |
| Clay Hensley | Ari | sp | 28 | 2 | 0 | 0 | 0 | 2 | 0 | 2 | 1 | 10.0 | 4.7 | 14.7 | 6.5 | 0.6 | 1.4 | 1.63 |
| Matt Herges | Pit | mr | 38 | 0 | 1 | 1 | 2 | 2 | 0 | 0 | 1 | 4.2 | 1.4 | 5.9 | 5.6 | 1.0 | 4.1 | 0.62 |
| Felix Hernandez | Bal | sp | 22 | 9 | 6 | 1 | 5 | 7 | 1 | 3 | 5 | 10.5 | 3.2 | 13.9 | 8.5 | 0.9 | 2.6 | 1.52 |
| Livan Hernandez | Atl | sp | 33 | 32 | 2 | 7 | 4 | 1 | 0 | 8 | 8 | 11.4 | 3.9 | 15.5 | 3.7 | 1.8 | 0.9 | 1.71 |
| Orlando Hernandez | ChC | sp | 38 | 17 | 5 | 6 | 7 | 4 | 0 | 7 | 4 | 7.3 | 4.4 | 12.2 | 7.8 | 1.8 | 1.8 | 1.31 |
| Roberto Hernandez | Atl | mr | 43 | 3 | 0 | 0 | 7 | 4 | 0 | 5 | 2 | 12.9 | 3.6 | 17.7 | 5.1 | 1.1 | 1.4 | 1.84 |
| Rich Hill* | ChC | sp | 28 | 9 | 3 | 4 | 7 | 1 | 2 | 10 | 9 | 7.6 | 3.4 | 11.4 | 8.2 | 1.4 | 2.4 | 1.23 |
| Shawn Hill | Tam | sp | 27 | 15 | 4 | 5 | 6 | 2 | 0 | 0 | 4 | 8.8 | 3.0 | 12.1 | 6.2 | 1.0 | 2.1 | 1.31 |
| Jason Hirsh | Ari | sp | 26 | 3 | 3 | 2 | 3 | 5 | 0 | 4 | 7 | 9.7 | 3.5 | 13.4 | 6.0 | 2.1 | 1.7 | 1.46 |
| Luke Hochevar | Mil | mr | 24 | 0 | 0 | 0 | 3 | 2 | 0 | 0 | 0 | 6.1 | 1.7 | 10.5 | 0.9 | 0.0 | 0.5 | 0.87 |
| Jim Hoey | NYM | mr | 25 | 3 | 1 | 3 | 0 | 1 | 1 | 1 | 0 | 12.2 | 10.1 | 22.2 | 4.8 | 1.1 | 0.5 | 2.47 |
| Trevor Hoffman | SD | cl | 40 | 1 | 1 | 6 | 1 | 0 | 0 | 0 | 5 | 7.2 | 1.5 | 8.8 | 5.7 | 0.5 | 3.8 | 0.97 |
| D.J. Houlton | Flo | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9.5 | 3.2 | 12.7 | 6.9 | 1.1 | 2.2 | 1.41 |
| J.P. Howell* | Flo | sp | 25 | 1 | 1 | 1 | 3 | 1 | 0 | 4 | 1 | 12.7 | 2.9 | 16.4 | 10.4 | 1.3 | 3.6 | 1.73 |
| Bob Howry | ChC | mr | 34 | 6 | 1 | 6 | 2 | 1 | 0 | 1 | 4 | 8.0 | 2.5 | 10.7 | 7.6 | 0.8 | 3.0 | 1.17 |
| Tim Hudson | Min | sp | 32 | 12 | 3 | 1 | 10 | 9 | 3 | 3 | 4 | 8.9 | 2.3 | 11.6 | 6.5 | 0.6 | 2.8 | 1.24 |
| Phil Hughes | SF | sp | 22 | 5 | 2 | 0 | 4 | 1 | 0 | 1 | 2 | 7.4 | 3.7 | 11.4 | 7.1 | 1.0 | 2.0 | 1.23 |
| Philip Humber | LAA | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 6.8 | 6.8 | 0.0 | 0.0 | 0.0 | 0.75 |
| Kei Igawa* | KC | sp | 28 | 1 | 5 | 5 | 12 | 11 | 2 | 3 | 8 | 9.7 | 5.2 | 15.5 | 7.4 | 1.9 | 1.4 | 1.65 |
| Jason Isringhausen | LAA | cl | 35 | 1 | 0 | 0 | 2 | 3 | 0 | 1 | 0 | 5.4 | 3.4 | 9.1 | 7.1 | 1.6 | 2.1 | 0.97 |
| Edwin Jackson | Hou | sp | 24 | 16 | 2 | 6 | 4 | 6 | 2 | 5 | 5 | 9.4 | 3.5 | 13.1 | 7.7 | 1.1 | 2.2 | 1.43 |
| Chuck James* | ChW | sp | 26 | 9 | 5 | 0 | 2 | 0 | 1 | 1 | 4 | 9.0 | 3.5 | 12.7 | 6.8 | 1.7 | 1.9 | 1.39 |
| Casey Janssen | LAA | mr | 26 | 2 | 2 | 1 | 3 | 3 | 0 | 3 | 3 | 8.8 | 4.0 | 13.2 | 4.9 | 0.3 | 1.2 | 1.42 |
| Bobby Jenks | Pit | cl | 27 | 1 | 2 | 0 | 1 | 4 | 0 | 0 | 4 | 5.9 | 0.9 | 6.9 | 7.7 | 0.1 | 8.9 | 0.75 |
| Jason Jennings | Cle | sp | 29 | 5 | 0 | 2 | 1 | 1 | 0 | 0 | 1 | 10.2 | 3.5 | 13.9 | 7.1 | 0.9 | 2.1 | 1.52 |
| Ubaldo Jimenez | NYY | sp | 24 | 5 | 1 | 0 | 6 | 3 | 0 | 2 | 4 | 9.4 | 4.7 | 14.7 | 7.5 | 1.6 | 1.6 | 1.56 |
| Josh Johnson | NYY | sp | 24 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 20.9 | 10.8 | 31.7 | 6.1 | 4.0 | 0.6 | 3.52 |
| Randy Johnson* | NYM | sp | 44 | 6 | 1 | 2 | 5 | 1 | 0 | 3 | 1 | 7.4 | 2.1 | 10.0 | 12.4 | 1.7 | 6.0 | 1.05 |
| Tyler Johnson* | Cle | mr | 27 | 2 | 0 | 0 | 3 | 5 | 0 | 2 | 4 | 6.3 | 2.1 | 9.0 | 7.3 | 0.4 | 3.5 | 0.93 |
| Todd Jones | ChC | cl | 40 | 5 | 2 | 3 | 3 | 4 | 0 | 0 | 4 | 9.1 | 2.4 | 11.8 | 4.5 | 0.6 | 1.9 | 1.28 |
| Jorge Julio | Phi | mr | 29 | 10 | 0 | 1 | 3 | 9 | 1 | 2 | 5 | 11.3 | 5.3 | 16.9 | 9.0 | 1.0 | 1.7 | 1.85 |
| Jair Jurrjens | Mil | sp | 22 | 3 | 0 | 2 | 2 | 1 | 0 | 0 | 0 | 5.1 | 3.3 | 8.9 | 3.8 | 1.0 | 1.2 | 0.93 |
| Jeff Karstens | Cin | mr | 25 | 0 | 3 | 3 | 0 | 0 | 0 | 1 | 0 | 17.5 | 9.4 | 27.0 | 3.4 | 1.3 | 0.4 | 3.00 |
| Scott Kazmir* | SF | sp | 24 | 17 | 7 | 4 | 9 | 14 | 0 | 7 | 4 | 8.6 | 3.6 | 12.5 | 10.2 | 0.6 | 2.9 | 1.35 |
| Kyle Kendrick | LAD | sp | 23 | 10 | 1 | 3 | 7 | 0 | 0 | 5 | 3 | 10.1 | 2.1 | 12.7 | 3.1 | 1.5 | 1.5 | 1.36 |
| Ian Kennedy | Phi | sp | 23 | 1 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 9.1 | 4.0 | 13.2 | 8.4 | 0.7 | 2.1 | 1.46 |
| Joe Kennedy* | Phi | mr | 29 | 3 | 3 | 7 | 13 | 14 | 0 | 11 | 6 | 11.4 | 4.1 | 16.4 | 3.9 | 1.4 | 0.9 | 1.73 |
| Logan Kensing | Mil | mr | 25 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.0 | 3.3 | 7.2 | 7.9 | 0.7 | 2.4 | 0.80 |
| Byung-Hyun Kim | Tam | sp | 29 | 3 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 7.9 | 4.8 | 13.1 | 7.7 | 1.4 | 1.6 | 1.41 |
| Ray King* | KC | mr | 34 | 8 | 4 | 8 | 4 | 4 | 0 | 0 | 4 | 9.7 | 6.9 | 17.0 | 5.0 | 1.4 | 0.7 | 1.84 |
| Steve Kline* | StL | mr | 35 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 6 | 13.6 | 3.1 | 16.8 | 3.2 | 0.7 | 1.1 | 1.85 |
| Mike Koplove | Col | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.5 | 4.5 | 9.0 | 2.3 | 0.0 | 0.5 | 1.00 |
| Hong-Chih Kuo* | Sea | sp | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 5.6 | 2.8 | 8.4 | 2.8 | 0.0 | 1.0 | 0.93 |
| John Lackey | Hou | sp | 29 | 18 | 3 | 3 | 17 | 11 | 1 | 5 | 5 | 9.4 | 1.7 | 11.8 | 7.6 | 0.9 | 4.4 | 1.24 |
| Aaron Laffey* | ChW | sp | 23 | 3 | 1 | 0 | 3 | 3 | 1 | 1 | 1 | 8.5 | 1.8 | 10.7 | 4.8 | 0.5 | 2.6 | 1.14 |
| John Lannan* | Mil | sp | 23 | 3 | 0 | 0 | 1 | 1 | 0 | 1 | 3 | 14.4 | 5.5 | 20.1 | 0.9 | 0.9 | 0.2 | 2.20 |
| Brian Lawrence | Phi | sp | 32 | 7 | 1 | 1 | 0 | 2 | 0 | 0 | 2 | 18.7 | 7.2 | 25.9 | 5.4 | 1.8 | 0.8 | 2.88 |
| Cliff Lee* | Cle | sp | 29 | 9 | 1 | 3 | 5 | 5 | 0 | 2 | 7 | 12.1 | 4.0 | 16.6 | 6.5 | 1.9 | 1.6 | 1.79 |
| Jon Lester* | Sea | sp | 24 | 3 | 3 | 0 | 2 | 2 | 0 | 1 | 3 | 7.2 | 3.7 | 11.1 | 5.4 | 0.7 | 1.5 | 1.21 |
| Jensen Lewis | Min | mr | 24 | 0 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 7.3 | 3.4 | 11.2 | 9.4 | 0.5 | 2.7 | 1.19 |
| Brad Lidge | Atl | cl | 31 | 4 | 0 | 1 | 7 | 6 | 0 | 1 | 4 | 7.1 | 2.4 | 10.1 | 12.3 | 1.3 | 5.2 | 1.05 |
| Jon Lieber | Phi | sp | 38 | 1 | 0 | 2 | 3 | 1 | 0 | 4 | 5 | 12.6 | 2.7 | 15.7 | 7.5 | 0.8 | 2.8 | 1.70 |
| Ted Lilly* | Hou | sp | 32 | 14 | 8 | 5 | 4 | 5 | 0 | 9 | 4 | 8.1 | 2.1 | 10.4 | 7.6 | 1.2 | 3.6 | 1.13 |
| Tim Lincecum | Tor | sp | 24 | 4 | 1 | 0 | 4 | 9 | 0 | 1 | 3 | 8.8 | 3.6 | 12.6 | 10.0 | 1.2 | 2.8 | 1.38 |
| Matt Lindstrom | Bos | mr | 28 | 3 | 2 | 3 | 4 | 6 | 0 | 3 | 4 | 9.7 | 3.8 | 13.9 | 8.8 | 0.4 | 2.3 | 1.50 |
| Scott Linebrink | Mil | mr | 31 | 13 | 1 | 4 | 1 | 5 | 0 | 5 | 3 | 8.8 | 3.1 | 12.0 | 7.7 | 1.6 | 2.5 | 1.33 |
| Jesse Litsch | Cin | sp | 23 | 2 | 1 | 3 | 5 | 1 | 0 | 1 | 3 | 8.0 | 3.1 | 11.6 | 3.7 | 0.8 | 1.2 | 1.24 |
| Wes Littleton | Cin | mr | 25 | 3 | 1 | 3 | 4 | 0 | 0 | 1 | 0 | 7.4 | 2.5 | 10.5 | 3.6 | 1.5 | 1.4 | 1.10 |
| Bobby Livingston* | Col | sp | 25 | 10 | 0 | 1 | 4 | 3 | 5 | 11 | 7 | 13.8 | 1.3 | 15.3 | 4.9 | 1.2 | 3.8 | 1.67 |
| Radhames Liz | Bal | mr | 25 | 2 | 0 | 0 | 1 | 6 | 0 | 0 | 2 | 9.1 | 9.5 | 18.9 | 8.1 | 2.1 | 0.9 | 2.07 |
| Esteban Loaiza | Flo | sp | 36 | 2 | 5 | 0 | 1 | 0 | 1 | 2 | 3 | 15.1 | 8.0 | 23.5 | 5.8 | 5.1 | 0.7 | 2.57 |
| Kameron Loe | Bos | sp | 26 | 14 | 4 | 4 | 7 | 6 | 0 | 0 | 7 | 11.4 | 3.4 | 15.2 | 6.4 | 1.2 | 1.9 | 1.65 |
| Adam Loewen* | LAA | sp | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 5.0 | 5.5 | 10.5 | 9.5 | 0.5 | 1.7 | 1.17 |
| Boone Logan* | Cle | mr | 23 | 1 | 0 | 3 | 1 | 1 | 0 | 0 | 0 | 10.8 | 4.8 | 16.2 | 3.6 | 1.2 | 0.8 | 1.73 |
| Kyle Lohse | Bal | sp | 29 | 16 | 2 | 0 | 4 | 5 | 0 | 1 | 12 | 9.9 | 4.0 | 14.1 | 6.0 | 0.7 | 1.5 | 1.54 |
| Braden Looper | Cle | sp | 33 | 12 | 4 | 1 | 9 | 0 | 1 | 2 | 6 | 8.2 | 2.4 | 11.0 | 5.4 | 1.0 | 2.3 | 1.18 |
| Aquilino Lopez | Sea | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 0.0 | 6.8 | 0.0 | 6.8 | 0.0 | 0.75 |
| Javier Lopez* | Col | mr | 30 | 2 | 1 | 0 | 4 | 4 | 0 | 1 | 2 | 8.3 | 4.7 | 13.6 | 5.1 | 1.3 | 1.1 | 1.45 |
| Rodrigo Lopez | StL | sp | 32 | 16 | 3 | 0 | 1 | 0 | 0 | 8 | 7 | 10.2 | 2.7 | 13.0 | 5.0 | 0.9 | 1.8 | 1.44 |
| Derek Lowe | ChW | sp | 35 | 22 | 2 | 0 | 2 | 3 | 1 | 2 | 4 | 8.5 | 3.8 | 12.4 | 6.6 | 1.0 | 1.7 | 1.37 |
| Mark Lowe | StL | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 21.0 | 6.0 | 27.0 | 9.0 | 3.0 | 1.5 | 3.00 |
| Noah Lowry* | Mil | sp | 27 | 5 | 5 | 8 | 6 | 9 | 0 | 8 | 4 | 10.4 | 5.5 | 16.2 | 5.9 | 1.7 | 1.1 | 1.76 |
| Ruddy Lugo | KC | mr | 28 | 2 | 1 | 2 | 3 | 2 | 0 | 0 | 3 | 9.0 | 4.9 | 14.2 | 7.1 | 1.1 | 1.5 | 1.54 |
| Brandon Lyon | Tam | mr | 28 | 5 | 1 | 1 | 3 | 8 | 1 | 3 | 3 | 7.5 | 2.9 | 10.7 | 5.6 | 0.3 | 1.9 | 1.16 |
| Mike MacDougal | Bal | mr | 31 | 5 | 0 | 1 | 1 | 6 | 0 | 1 | 0 | 11.6 | 4.9 | 16.8 | 9.8 | 1.1 | 2.0 | 1.83 |
| Greg Maddux | ChC | sp | 42 | 27 | 6 | 2 | 7 | 4 | 0 | 4 | 3 | 10.3 | 1.3 | 11.9 | 5.6 | 0.8 | 4.3 | 1.29 |
| Ryan Madson | NYM | mr | 27 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 7.3 | 2.7 | 10.2 | 6.6 | 0.4 | 2.5 | 1.11 |
| Ron Mahay* | Det | mr | 37 | 2 | 0 | 6 | 2 | 2 | 0 | 0 | 2 | 8.1 | 5.7 | 14.0 | 8.9 | 0.4 | 1.6 | 1.53 |
| Paul Maholm* | LAA | sp | 26 | 6 | 2 | 2 | 2 | 4 | 0 | 0 | 4 | 9.2 | 2.4 | 11.8 | 5.4 | 1.3 | 2.2 | 1.29 |
| John Maine | Oak | sp | 27 | 3 | 2 | 1 | 6 | 3 | 0 | 3 | 6 | 7.3 | 3.2 | 10.8 | 8.8 | 1.0 | 2.7 | 1.17 |
| Gary Majewski | Tex | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 13.5 | 0.6 | 14.1 | 5.6 | 1.7 | 10.0 | 1.56 |
| Shaun Marcum | Tam | sp | 26 | 5 | 5 | 3 | 1 | 0 | 0 | 3 | 3 | 7.7 | 2.5 | 10.3 | 7.2 | 1.5 | 2.8 | 1.14 |
| Carlos Marmol | Tam | mr | 25 | 4 | 2 | 2 | 2 | 7 | 4 | 2 | 3 | 5.0 | 4.5 | 9.7 | 11.9 | 0.1 | 2.6 | 1.05 |
| Jason Marquis | StL | sp | 29 | 31 | 7 | 4 | 13 | 3 | 0 | 11 | 8 | 9.6 | 3.8 | 13.9 | 5.1 | 0.8 | 1.4 | 1.48 |
| Jay Marshall* | Det | mr | 25 | 0 | 0 | 0 | 5 | 3 | 0 | 0 | 1 | 13.0 | 4.7 | 20.3 | 4.7 | 0.5 | 1.0 | 1.96 |
| Sean Marshall* | Flo | sp | 25 | 9 | 1 | 9 | 2 | 2 | 0 | 3 | 1 | 8.9 | 2.8 | 11.8 | 5.4 | 1.1 | 2.0 | 1.29 |
| Damaso Marte* | Ari | mr | 33 | 2 | 0 | 4 | 1 | 1 | 2 | 1 | 1 | 7.2 | 3.8 | 11.1 | 10.6 | 0.4 | 2.8 | 1.22 |
| Tom Martin* | Atl | mr | 38 | 4 | 1 | 0 | 4 | 4 | 2 | 5 | 5 | 13.5 | 3.3 | 17.2 | 3.1 | 1.9 | 0.9 | 1.87 |
| Carlos Martinez | Cin | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 15.8 | 4.5 | 20.3 | 4.5 | 9.0 | 1.0 | 2.25 |
| Pedro Martinez | Bos | sp | 36 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 1 | 9.3 | 2.6 | 12.4 | 11.9 | 0.5 | 4.5 | 1.32 |
| Nick Masset | Oak | mr | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 18.0 | 10.5 | 28.5 | 4.5 | 3.0 | 0.4 | 3.17 |
| Tom Mastny | KC | mr | 27 | 11 | 0 | 2 | 3 | 11 | 0 | 2 | 3 | 9.3 | 3.5 | 13.0 | 9.2 | 1.1 | 2.6 | 1.43 |
| Julio Mateo | Cin | mr | 30 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 10.9 | 1.5 | 12.4 | 3.6 | 0.7 | 2.5 | 1.38 |
| Daisuke Matsuzaka | Cle | sp | 27 | 23 | 6 | 1 | 9 | 6 | 0 | 1 | 4 | 7.4 | 4.1 | 11.9 | 8.8 | 0.9 | 2.2 | 1.28 |
| Marcus McBeth | Bos | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 9.0 | 36.0 | 0.0 | 0.0 | 0.0 | 4.00 |
| Macay McBride* | Ari | mr | 25 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 1 | 6.1 | 4.6 | 11.4 | 8.4 | 0.0 | 1.8 | 1.18 |
| Brandon McCarthy | Ari | sp | 24 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 5 | 10.1 | 3.3 | 13.6 | 5.8 | 0.6 | 1.8 | 1.49 |
| Seth McClung | Mil | mr | 27 | 1 | 1 | 2 | 0 | 1 | 0 | 0 | 2 | 10.0 | 8.2 | 18.2 | 7.6 | 0.0 | 0.9 | 2.02 |
| Dustin McGowan | Sea | sp | 26 | 13 | 5 | 5 | 5 | 10 | 0 | 2 | 1 | 6.8 | 3.1 | 10.2 | 7.3 | 0.4 | 2.3 | 1.10 |
| Marty McLeary | NYM | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 9.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Mark McLemore* | NYY | mr | 27 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 12.1 | 7.2 | 19.3 | 11.0 | 1.7 | 1.5 | 2.14 |
| Gil Meche | Sea | sp | 29 | 5 | 0 | 1 | 3 | 0 | 0 | 4 | 4 | 8.0 | 1.8 | 10.0 | 6.2 | 0.9 | 3.4 | 1.09 |
| Brandon Medders | NYY | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3 | 7.9 | 3.8 | 11.6 | 8.6 | 2.3 | 2.3 | 1.29 |
| Luis Mendoza | Mil | sp | 24 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 7.1 | 1.6 | 10.3 | 4.8 | 0.8 | 3.0 | 0.97 |
| Cla Meredith | Col | mr | 25 | 5 | 3 | 1 | 2 | 2 | 1 | 4 | 1 | 12.2 | 1.9 | 14.3 | 7.1 | 0.9 | 3.7 | 1.57 |
| Jose Mesa | NYM | mr | 42 | 2 | 0 | 3 | 1 | 2 | 0 | 1 | 2 | 8.7 | 4.7 | 13.6 | 4.7 | 1.0 | 1.0 | 1.49 |
| Randy Messenger | Phi | mr | 26 | 8 | 3 | 2 | 3 | 1 | 0 | 0 | 6 | 14.0 | 3.2 | 17.5 | 5.7 | 1.4 | 1.8 | 1.91 |
| Dan Meyer* | Oak | sp | 26 | 2 | 1 | 0 | 0 | 3 | 1 | 1 | 2 | 14.5 | 6.3 | 20.7 | 4.5 | 2.3 | 0.7 | 2.31 |
| Andrew Miller* | Mil | sp | 23 | 3 | 1 | 7 | 2 | 4 | 0 | 2 | 3 | 14.5 | 7.8 | 22.6 | 8.1 | 2.2 | 1.0 | 2.47 |
| Justin Miller | LAD | mr | 30 | 1 | 0 | 7 | 2 | 2 | 0 | 1 | 1 | 8.3 | 3.7 | 12.3 | 10.2 | 0.6 | 2.8 | 1.34 |
| Trever Miller* | Phi | mr | 35 | 2 | 0 | 1 | 2 | 1 | 0 | 1 | 3 | 12.9 | 4.5 | 17.9 | 7.2 | 1.4 | 1.6 | 1.94 |
| Kevin Millwood | StL | sp | 33 | 12 | 3 | 1 | 10 | 2 | 0 | 10 | 8 | 10.1 | 2.4 | 13.1 | 6.4 | 0.6 | 2.7 | 1.39 |
| Zach Miner | Pit | mr | 26 | 6 | 1 | 1 | 2 | 0 | 0 | 2 | 2 | 11.9 | 2.9 | 15.1 | 4.3 | 0.6 | 1.5 | 1.64 |
| Patrick Misch* | NYM | mr | 26 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 14.8 | 0.6 | 15.4 | 3.9 | 0.6 | 6.0 | 1.71 |
| Sergio Mitre | Cin | sp | 27 | 15 | 6 | 2 | 12 | 3 | 0 | 8 | 1 | 10.8 | 2.8 | 14.3 | 4.9 | 0.6 | 1.8 | 1.51 |
| Brian Moehler | Tor | mr | 36 | 3 | 0 | 10 | 2 | 1 | 0 | 2 | 2 | 9.5 | 2.8 | 12.5 | 6.0 | 0.8 | 2.1 | 1.37 |
| Franklin Morales* | Flo | sp | 22 | 9 | 1 | 2 | 1 | 0 | 0 | 1 | 1 | 7.9 | 3.2 | 11.2 | 5.6 | 0.8 | 1.8 | 1.22 |
| Juan Morillo | Bos | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.00 |
| Matt Morris | Oak | sp | 33 | 9 | 5 | 0 | 13 | 3 | 0 | 1 | 6 | 10.1 | 2.7 | 13.3 | 4.9 | 1.0 | 1.8 | 1.42 |
| Brandon Morrow | LAA | mr | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.5 | 7.4 | 9.8 | 7.4 | 0.0 | 1.0 | 1.09 |
| Dustin Moseley | Was | mr | 26 | 3 | 1 | 6 | 1 | 6 | 3 | 2 | 6 | 7.8 | 2.5 | 10.4 | 3.8 | 0.4 | 1.5 | 1.14 |
| Guillermo Mota | Bal | mr | 34 | 10 | 0 | 0 | 3 | 2 | 0 | 1 | 4 | 9.2 | 2.7 | 12.2 | 7.8 | 0.6 | 3.0 | 1.31 |
| Jamie Moyer* | Phi | sp | 45 | 16 | 2 | 4 | 7 | 3 | 0 | 6 | 8 | 11.7 | 2.5 | 14.4 | 6.2 | 1.7 | 2.5 | 1.57 |
| Peter Moylan | Cin | mr | 29 | 14 | 2 | 3 | 6 | 0 | 0 | 5 | 3 | 8.0 | 2.0 | 10.4 | 6.9 | 1.0 | 3.4 | 1.11 |
| Arnie Munoz* | Phi | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 15.3 | 11.7 | 27.0 | 5.1 | 2.2 | 0.4 | 3.00 |
| A.J. Murray* | Det | mr | 26 | 2 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 9.0 | 5.0 | 14.3 | 6.2 | 1.6 | 1.3 | 1.55 |
| Mike Mussina | SD | sp | 39 | 15 | 7 | 4 | 2 | 1 | 0 | 8 | 5 | 13.2 | 2.4 | 15.7 | 5.8 | 1.3 | 2.4 | 1.73 |
| Brett Myers | LAA | cl | 27 | 1 | 0 | 1 | 3 | 6 | 0 | 0 | 3 | 6.8 | 5.1 | 12.3 | 10.8 | 0.7 | 2.1 | 1.33 |
| Mike Myers* | Tex | mr | 39 | 3 | 0 | 1 | 5 | 3 | 0 | 1 | 2 | 7.8 | 3.0 | 11.4 | 3.2 | 1.0 | 1.1 | 1.20 |
| Joe Nathan | ChW | cl | 33 | 1 | 1 | 0 | 0 | 3 | 0 | 0 | 1 | 6.2 | 1.3 | 7.4 | 10.5 | 0.3 | 8.3 | 0.83 |
| Pat Neshek | Ari | mr | 27 | 3 | 3 | 1 | 5 | 4 | 0 | 3 | 1 | 5.5 | 2.4 | 8.4 | 9.5 | 0.7 | 4.0 | 0.88 |
| Dustin Nippert | ChW | mr | 27 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 2 | 10.9 | 2.8 | 13.6 | 8.6 | 1.9 | 3.1 | 1.52 |
| Ricky Nolasco | Cin | sp | 25 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 13.3 | 2.4 | 16.1 | 5.1 | 1.4 | 2.1 | 1.75 |
| Leo Nunez | NYM | mr | 24 | 3 | 1 | 2 | 0 | 0 | 0 | 0 | 1 | 7.2 | 1.3 | 8.5 | 7.7 | 2.1 | 5.9 | 0.94 |
| Eric O'Flaherty* | NYM | mr | 23 | 6 | 1 | 10 | 11 | 4 | 1 | 2 | 3 | 10.2 | 4.3 | 15.7 | 6.7 | 0.3 | 1.6 | 1.61 |
| Tomo Ohka | Mil | sp | 32 | 0 | 0 | 1 | 1 | 1 | 0 | 7 | 2 | 8.1 | 3.6 | 11.8 | 4.3 | 0.5 | 1.2 | 1.30 |
| Ross Ohlendorf | NYM | mr | 25 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 8.1 | 8.1 | 16.2 | 8.1 | 0.0 | 1.0 | 1.80 |
| Will Ohman* | StL | mr | 30 | 6 | 3 | 3 | 1 | 2 | 1 | 2 | 4 | 9.1 | 3.7 | 13.0 | 6.4 | 0.4 | 1.7 | 1.42 |
| Hideki Okajima* | SD | mr | 32 | 4 | 1 | 1 | 0 | 1 | 0 | 2 | 0 | 5.3 | 2.5 | 7.8 | 6.7 | 0.1 | 2.6 | 0.87 |
| Darren Oliver* | Cle | mr | 37 | 7 | 1 | 0 | 3 | 1 | 0 | 0 | 2 | 10.4 | 4.7 | 15.8 | 8.9 | 0.8 | 1.9 | 1.69 |
| Scott Olsen* | Hou | sp | 24 | 1 | 2 | 2 | 0 | 1 | 0 | 1 | 0 | 12.5 | 4.7 | 17.1 | 7.8 | 1.0 | 1.7 | 1.90 |
| Garrett Olson* | Was | sp | 24 | 0 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 13.9 | 7.3 | 23.4 | 4.4 | 2.2 | 0.6 | 2.35 |
| Ramon Ortiz | Pit | mr | 35 | 6 | 0 | 2 | 10 | 3 | 4 | 5 | 5 | 10.0 | 1.5 | 12.2 | 4.5 | 1.6 | 3.0 | 1.28 |
| Russ Ortiz | StL | sp | 34 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 19.5 | 0.0 | 19.5 | 4.5 | 6.0 | 99.0 | 2.17 |
| Chad Orvella | Col | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 27.0 | 10.8 | 37.8 | 5.4 | 5.4 | 0.5 | 4.20 |
| Franquelis Osoria | Tex | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 8.6 | 2.9 | 12.1 | 5.2 | 1.1 | 1.8 | 1.28 |
| Roy Oswalt | Ari | sp | 30 | 9 | 4 | 4 | 16 | 1 | 0 | 12 | 8 | 9.6 | 3.0 | 13.4 | 6.5 | 0.7 | 2.2 | 1.41 |
| Akinori Otsuka | Tex | mr | 36 | 2 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 7.7 | 3.1 | 10.8 | 5.9 | 0.4 | 1.9 | 1.20 |
| Henry Owens | NYY | mr | 29 | 1 | 0 | 4 | 0 | 3 | 0 | 0 | 2 | 7.1 | 4.6 | 11.6 | 6.6 | 1.2 | 1.5 | 1.29 |
| Micah Owings | LAA | sp | 25 | 6 | 2 | 2 | 11 | 13 | 0 | 1 | 6 | 7.7 | 3.1 | 11.4 | 6.5 | 0.9 | 2.1 | 1.20 |
| Vicente Padilla | Flo | sp | 30 | 8 | 1 | 6 | 5 | 3 | 0 | 4 | 6 | 10.5 | 3.8 | 14.6 | 6.4 | 0.6 | 1.7 | 1.58 |
| Jonathan Papelbon | LAD | cl | 27 | 3 | 0 | 0 | 7 | 0 | 0 | 3 | 3 | 4.8 | 2.0 | 7.6 | 11.5 | 0.9 | 5.8 | 0.75 |
| Manny Parra* | Hou | mr | 25 | 1 | 0 | 1 | 2 | 2 | 0 | 0 | 0 | 12.3 | 5.5 | 19.0 | 6.1 | 0.0 | 1.1 | 1.98 |
| John Parrish* | Min | mr | 30 | 0 | 0 | 2 | 0 | 6 | 0 | 0 | 0 | 13.8 | 8.0 | 21.8 | 8.7 | 0.7 | 1.1 | 2.42 |
| Troy Patton* | Cle | sp | 22 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 18.0 | 8.3 | 27.0 | 8.3 | 5.3 | 1.0 | 2.92 |
| Felipe Paulino | Mil | sp | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 13.2 | 2.8 | 15.9 | 2.8 | 3.5 | 1.0 | 1.77 |
| Carl Pavano | NYY | sp | 32 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 8.6 | 2.6 | 11.1 | 4.3 | 0.0 | 1.7 | 1.24 |
| Jake Peavy | SD | sp | 27 | 13 | 8 | 2 | 7 | 6 | 0 | 10 | 5 | 7.4 | 2.2 | 9.9 | 9.9 | 0.6 | 4.5 | 1.07 |
| Mike Pelfrey | NYM | sp | 24 | 2 | 1 | 4 | 7 | 1 | 0 | 6 | 6 | 12.5 | 4.7 | 18.2 | 5.1 | 0.9 | 1.1 | 1.92 |
| Tony Pena | SF | mr | 26 | 2 | 0 | 3 | 5 | 7 | 3 | 4 | 3 | 7.0 | 3.3 | 10.8 | 7.9 | 0.9 | 2.4 | 1.15 |
| Brad Penny | Tam | sp | 30 | 24 | 4 | 0 | 7 | 8 | 0 | 4 | 5 | 9.7 | 4.2 | 14.3 | 6.3 | 0.8 | 1.5 | 1.54 |
| Joel Peralta | Tam | mr | 32 | 5 | 2 | 0 | 1 | 3 | 0 | 3 | 4 | 10.7 | 1.9 | 12.6 | 6.1 | 1.6 | 3.3 | 1.40 |
| Troy Percival | SD | mr | 38 | 1 | 3 | 3 | 1 | 8 | 0 | 2 | 4 | 6.4 | 3.3 | 9.8 | 7.7 | 0.3 | 2.4 | 1.07 |
| Odalis Perez* | Cin | sp | 31 | 15 | 2 | 7 | 6 | 7 | 0 | 7 | 3 | 10.2 | 3.2 | 13.8 | 4.5 | 0.9 | 1.4 | 1.50 |
| Oliver Perez* | Min | sp | 26 | 5 | 0 | 1 | 7 | 5 | 0 | 6 | 6 | 8.7 | 4.6 | 13.7 | 8.2 | 1.0 | 1.8 | 1.48 |
| Rafael Perez* | NYY | mr | 26 | 1 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 4.9 | 1.2 | 6.4 | 9.7 | 0.7 | 8.4 | 0.67 |
| Glen Perkins* | Pit | mr | 25 | 0 | 0 | 1 | 2 | 4 | 0 | 0 | 0 | 6.7 | 5.5 | 12.9 | 6.7 | 0.0 | 1.2 | 1.36 |
| Yusmeiro Petit | Tam | sp | 23 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 9.5 | 3.8 | 13.3 | 7.1 | 1.1 | 1.9 | 1.48 |
| Billy Petrick | Min | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 9.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Andy Pettitte* | Tex | sp | 36 | 21 | 2 | 0 | 3 | 5 | 0 | 0 | 11 | 11.7 | 3.3 | 15.1 | 6.0 | 0.6 | 1.8 | 1.67 |
| Joel Pineiro | Bal | mr | 29 | 3 | 1 | 0 | 1 | 3 | 0 | 2 | 7 | 10.5 | 3.3 | 13.9 | 5.8 | 1.8 | 1.8 | 1.53 |
| Renyel Pinto* | Bos | mr | 25 | 1 | 0 | 6 | 6 | 3 | 0 | 1 | 2 | 8.2 | 9.6 | 18.7 | 10.7 | 1.3 | 1.1 | 1.98 |
| Sidney Ponson | Flo | sp | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 29.1 | 2.1 | 31.2 | 10.4 | 8.3 | 5.0 | 3.46 |
| Scott Proctor | LAA | mr | 31 | 3 | 0 | 0 | 6 | 2 | 0 | 2 | 2 | 8.0 | 4.3 | 13.5 | 7.6 | 1.6 | 1.8 | 1.36 |
| J.J. Putz | SD | cl | 31 | 0 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 3.7 | 1.6 | 5.3 | 8.4 | 0.4 | 5.4 | 0.59 |
| Chad Qualls | LAD | mr | 29 | 9 | 2 | 0 | 7 | 2 | 0 | 6 | 2 | 10.1 | 2.5 | 13.4 | 9.5 | 0.7 | 3.8 | 1.40 |
| Edwar Ramirez | NYY | mr | 27 | 1 | 0 | 1 | 2 | 2 | 0 | 0 | 1 | 12.5 | 6.2 | 20.8 | 18.7 | 1.0 | 3.0 | 2.08 |
| Elizardo Ramirez | Phi | sp | 25 | 4 | 0 | 1 | 0 | 0 | 1 | 2 | 2 | 9.5 | 4.9 | 14.5 | 6.1 | 1.5 | 1.2 | 1.61 |
| Horacio Ramirez* | KC | sp | 28 | 10 | 4 | 3 | 3 | 2 | 0 | 3 | 8 | 12.2 | 4.2 | 16.6 | 3.0 | 1.2 | 0.7 | 1.83 |
| Ramon Ramirez | Col | mr | 26 | 1 | 1 | 0 | 2 | 3 | 0 | 1 | 0 | 9.4 | 1.5 | 11.5 | 4.6 | 0.6 | 3.0 | 1.21 |
| Darrell Rasner | Tex | sp | 27 | 6 | 0 | 1 | 6 | 1 | 0 | 0 | 4 | 11.9 | 3.8 | 17.1 | 3.8 | 2.0 | 1.0 | 1.75 |
| Jon Rauch | ChW | mr | 29 | 5 | 0 | 0 | 1 | 2 | 0 | 1 | 1 | 8.3 | 1.4 | 9.8 | 7.6 | 0.5 | 5.4 | 1.08 |
| Chris Ray | Flo | cl | 26 | 1 | 0 | 1 | 3 | 0 | 0 | 3 | 2 | 7.7 | 2.3 | 10.5 | 10.0 | 1.3 | 4.3 | 1.11 |
| Tim Redding | SF | sp | 30 | 13 | 4 | 2 | 8 | 1 | 2 | 10 | 5 | 8.9 | 4.5 | 14.1 | 5.2 | 0.7 | 1.2 | 1.49 |
| Mark Redman* | ChC | sp | 34 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 22.8 | 6.2 | 29.1 | 4.2 | 2.1 | 0.7 | 3.23 |
| Al Reyes | Flo | cl | 38 | 3 | 0 | 1 | 0 | 1 | 0 | 3 | 3 | 6.7 | 2.7 | 9.4 | 11.5 | 1.8 | 4.3 | 1.04 |
| Anthony Reyes | Hou | sp | 26 | 8 | 3 | 2 | 8 | 1 | 3 | 2 | 4 | 9.2 | 3.1 | 12.8 | 5.8 | 1.5 | 1.9 | 1.36 |
| Dennys Reyes* | Bal | mr | 31 | 0 | 0 | 1 | 3 | 5 | 0 | 0 | 1 | 12.3 | 8.8 | 21.8 | 7.0 | 1.0 | 0.8 | 2.33 |
| Jo-Jo Reyes* | Ari | sp | 23 | 5 | 3 | 0 | 1 | 0 | 0 | 1 | 2 | 8.3 | 6.2 | 14.6 | 5.5 | 1.5 | 0.9 | 1.61 |
| John Rheinecker* | StL | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.4 | 10.4 | 20.8 | 8.3 | 0.0 | 0.8 | 2.31 |
| Juan Rincon | Tex | mr | 29 | 3 | 2 | 4 | 3 | 5 | 0 | 2 | 3 | 9.0 | 4.8 | 14.1 | 7.1 | 1.5 | 1.5 | 1.53 |
| David Riske | Bal | mr | 31 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 7.2 | 3.0 | 10.2 | 7.0 | 0.8 | 2.4 | 1.13 |
| Mariano Rivera | Flo | cl | 38 | 4 | 2 | 2 | 7 | 0 | 0 | 0 | 0 | 9.6 | 1.6 | 12.0 | 8.2 | 0.8 | 5.2 | 1.24 |
| Saul Rivera | Cin | mr | 30 | 5 | 1 | 3 | 1 | 6 | 0 | 6 | 5 | 10.3 | 4.4 | 14.7 | 5.4 | 0.3 | 1.2 | 1.63 |
| Nate Robertson* | Was | sp | 30 | 12 | 5 | 15 | 7 | 3 | 1 | 14 | 10 | 9.1 | 3.6 | 13.0 | 5.0 | 0.8 | 1.4 | 1.41 |
| Fernando Rodney | KC | mr | 31 | 3 | 2 | 3 | 3 | 5 | 0 | 0 | 1 | 9.3 | 3.7 | 13.4 | 9.5 | 1.7 | 2.6 | 1.45 |
| Francisco Rodriguez | Col | cl | 26 | 6 | 2 | 1 | 4 | 9 | 2 | 1 | 2 | 6.4 | 3.9 | 10.8 | 13.4 | 0.6 | 3.5 | 1.14 |
| Wandy Rodriguez* | Min | sp | 29 | 4 | 4 | 0 | 5 | 4 | 0 | 1 | 10 | 9.8 | 3.8 | 13.9 | 6.4 | 0.5 | 1.7 | 1.52 |
| Kenny Rogers* | NYM | sp | 43 | 1 | 1 | 4 | 3 | 0 | 0 | 7 | 2 | 10.0 | 3.0 | 13.4 | 4.7 | 1.2 | 1.5 | 1.45 |
| J.C. Romero* | Was | mr | 32 | 0 | 0 | 7 | 2 | 1 | 0 | 4 | 1 | 5.4 | 7.2 | 12.9 | 5.5 | 0.0 | 0.8 | 1.40 |
| Ryan Rowland-Smith* | SF | mr | 25 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 10.9 | 4.8 | 15.8 | 10.3 | 1.6 | 2.1 | 1.75 |
| Jae Kuk Ryu | Sea | mr | 25 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 16.2 | 16.2 | 32.4 | 10.8 | 0.0 | 0.7 | 3.60 |
| Kirk Saarloos | Phi | mr | 29 | 4 | 2 | 2 | 4 | 4 | 0 | 4 | 1 | 12.9 | 5.7 | 19.3 | 6.1 | 3.1 | 1.1 | 2.06 |
| C.C. Sabathia* | ChW | sp | 27 | 3 | 3 | 0 | 5 | 1 | 0 | 1 | 6 | 10.3 | 1.3 | 11.7 | 7.3 | 0.9 | 5.8 | 1.28 |
| Takashi Saito | SD | cl | 38 | 3 | 2 | 0 | 3 | 0 | 0 | 1 | 2 | 3.6 | 1.8 | 5.7 | 11.2 | 0.1 | 6.1 | 0.60 |
| Juan Salas | NYY | mr | 29 | 3 | 0 | 0 | 5 | 6 | 0 | 1 | 2 | 7.7 | 4.7 | 13.5 | 7.3 | 1.5 | 1.5 | 1.38 |
| Brad Salmon | Bal | mr | 28 | 3 | 1 | 2 | 0 | 3 | 0 | 0 | 3 | 11.7 | 3.2 | 15.0 | 9.7 | 1.8 | 3.0 | 1.66 |
| Chris Sampson | Min | sp | 30 | 4 | 1 | 0 | 6 | 3 | 0 | 2 | 4 | 10.7 | 2.5 | 13.6 | 4.0 | 1.7 | 1.6 | 1.47 |
| Anibal Sanchez | Bos | sp | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 14.2 | 2.8 | 17.1 | 4.3 | 1.4 | 1.5 | 1.89 |
| Jonathan Sanchez* | KC | mr | 25 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 6.3 | 4.5 | 10.8 | 10.8 | 0.0 | 2.4 | 1.20 |
| Romulo Sanchez | Col | mr | 24 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.0 | 7.0 | 16.0 | 10.0 | 2.0 | 1.4 | 1.78 |
| Ervin Santana | Bos | sp | 25 | 7 | 1 | 0 | 7 | 10 | 0 | 0 | 6 | 10.9 | 3.4 | 14.7 | 8.7 | 2.1 | 2.6 | 1.59 |
| Johan Santana* | Mil | sp | 29 | 5 | 1 | 4 | 6 | 3 | 0 | 3 | 1 | 8.6 | 1.7 | 10.6 | 9.8 | 1.7 | 5.7 | 1.15 |
| Victor Santos | NYY | mr | 31 | 1 | 0 | 0 | 1 | 3 | 0 | 2 | 2 | 13.4 | 4.4 | 18.0 | 8.0 | 2.3 | 1.8 | 1.98 |
| Dennis Sarfate | Sea | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.0 | 0.0 | 12.0 | 15.0 | 0.0 | 99.0 | 1.33 |
| Joe Saunders* | SF | sp | 27 | 11 | 3 | 5 | 3 | 2 | 0 | 3 | 4 | 10.2 | 2.6 | 13.1 | 6.9 | 0.4 | 2.6 | 1.43 |
| Curt Schilling | Mil | sp | 41 | 14 | 2 | 2 | 2 | 0 | 0 | 7 | 6 | 10.0 | 1.4 | 11.5 | 6.1 | 0.9 | 4.5 | 1.27 |
| Jason Schmidt | Phi | sp | 35 | 1 | 3 | 0 | 2 | 3 | 0 | 2 | 1 | 12.1 | 3.9 | 16.5 | 7.3 | 2.1 | 1.9 | 1.78 |
| Scott Schoeneweis* | NYM | mr | 34 | 3 | 2 | 5 | 3 | 2 | 1 | 3 | 1 | 10.0 | 4.7 | 15.0 | 6.3 | 1.9 | 1.4 | 1.63 |
| Chris Schroder | Tor | mr | 29 | 3 | 0 | 8 | 4 | 0 | 0 | 2 | 3 | 7.5 | 3.1 | 11.1 | 7.9 | 0.9 | 2.5 | 1.18 |
| Rudy Seanez | Tor | mr | 39 | 3 | 0 | 3 | 5 | 4 | 0 | 0 | 0 | 12.0 | 4.6 | 17.5 | 8.7 | 1.5 | 1.9 | 1.85 |
| Bobby Seay* | NYY | mr | 30 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 6.2 | 2.4 | 8.9 | 7.1 | 0.3 | 3.0 | 0.96 |
| Chris Seddon* | Cin | sp | 24 | 2 | 1 | 5 | 1 | 0 | 0 | 1 | 1 | 16.1 | 8.0 | 24.8 | 5.8 | 2.2 | 0.7 | 2.68 |
| Zack Segovia | Tor | sp | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 27.0 | 6.8 | 40.5 | 6.8 | 0.0 | 1.0 | 3.75 |
| Aaron Sele | NYY | mr | 38 | 0 | 0 | 2 | 4 | 1 | 0 | 1 | 3 | 14.3 | 4.4 | 19.5 | 5.9 | 0.6 | 1.3 | 2.08 |
| Jae Seo | LAD | sp | 31 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 13.8 | 4.0 | 18.4 | 4.6 | 3.3 | 1.2 | 1.98 |
| Tom Shearn | Flo | sp | 30 | 3 | 1 | 0 | 1 | 2 | 0 | 1 | 1 | 9.3 | 3.6 | 13.1 | 5.0 | 1.7 | 1.4 | 1.44 |
| Ben Sheets | Tex | sp | 29 | 13 | 3 | 0 | 7 | 5 | 0 | 3 | 5 | 8.2 | 2.8 | 11.4 | 6.8 | 1.2 | 2.4 | 1.23 |
| George Sherrill* | Min | mr | 31 | 0 | 1 | 5 | 3 | 1 | 2 | 3 | 6 | 6.4 | 3.8 | 10.5 | 10.7 | 0.7 | 2.8 | 1.13 |
| James Shields | LAD | sp | 26 | 9 | 6 | 7 | 19 | 8 | 0 | 6 | 9 | 8.0 | 1.7 | 10.4 | 8.0 | 1.1 | 4.9 | 1.07 |
| Scot Shields | SF | mr | 32 | 4 | 1 | 1 | 4 | 4 | 0 | 5 | 2 | 6.4 | 2.8 | 9.6 | 9.5 | 0.8 | 3.4 | 1.02 |
| Brian Shouse* | Sea | mr | 39 | 2 | 0 | 0 | 2 | 0 | 1 | 0 | 4 | 8.0 | 1.3 | 9.6 | 8.0 | 0.0 | 6.1 | 1.03 |
| Carlos Silva | Det | sp | 29 | 11 | 5 | 8 | 4 | 5 | 2 | 1 | 6 | 10.2 | 2.2 | 12.5 | 4.0 | 1.2 | 1.8 | 1.38 |
| Jason Simontacchi | NYM | sp | 34 | 6 | 1 | 3 | 2 | 0 | 0 | 6 | 3 | 12.1 | 2.5 | 14.8 | 7.7 | 1.6 | 3.0 | 1.62 |
| Andrew Sisco* | LAD | mr | 25 | 0 | 0 | 1 | 0 | 4 | 0 | 1 | 2 | 12.1 | 6.1 | 18.2 | 5.5 | 2.2 | 0.9 | 2.02 |
| Doug Slaten* | ChW | mr | 28 | 2 | 1 | 0 | 1 | 6 | 1 | 1 | 2 | 11.1 | 3.9 | 15.2 | 5.4 | 0.7 | 1.4 | 1.66 |
| Kevin Slowey | NYY | sp | 24 | 4 | 3 | 0 | 1 | 5 | 0 | 0 | 3 | 11.2 | 1.3 | 12.7 | 7.8 | 2.3 | 5.9 | 1.39 |
| Joe Smith | ChW | mr | 24 | 2 | 0 | 0 | 2 | 3 | 1 | 0 | 0 | 12.8 | 4.9 | 18.4 | 8.3 | 1.5 | 1.7 | 1.96 |
| John Smoltz | ChW | sp | 41 | 11 | 4 | 0 | 3 | 3 | 0 | 4 | 4 | 9.4 | 2.4 | 11.9 | 8.9 | 0.8 | 3.8 | 1.31 |
| Ian Snell | Was | sp | 26 | 16 | 4 | 5 | 12 | 16 | 0 | 7 | 4 | 7.4 | 2.5 | 10.4 | 7.4 | 0.7 | 3.0 | 1.10 |
| Kyle Snyder | Bos | mr | 30 | 8 | 3 | 1 | 7 | 6 | 0 | 0 | 7 | 6.0 | 4.8 | 11.7 | 5.8 | 0.8 | 1.2 | 1.21 |
| Andy Sonnanstine | Bos | sp | 25 | 1 | 3 | 1 | 6 | 1 | 0 | 1 | 5 | 9.8 | 2.2 | 12.4 | 5.6 | 0.8 | 2.6 | 1.33 |
| Joakim Soria | StL | cl | 24 | 2 | 0 | 0 | 3 | 2 | 0 | 4 | 2 | 6.6 | 1.6 | 8.6 | 10.5 | 0.3 | 6.7 | 0.91 |
| Rafael Soriano | Atl | mr | 28 | 7 | 5 | 1 | 3 | 0 | 0 | 3 | 2 | 6.6 | 1.8 | 8.7 | 8.1 | 1.2 | 4.6 | 0.93 |
| Jorge Sosa | Tor | mr | 31 | 1 | 1 | 9 | 4 | 0 | 0 | 1 | 5 | 10.4 | 3.9 | 14.5 | 6.4 | 1.5 | 1.7 | 1.58 |
| Jeremy Sowers* | Pit | sp | 25 | 7 | 0 | 5 | 5 | 6 | 0 | 5 | 6 | 9.6 | 2.5 | 12.7 | 4.3 | 1.2 | 1.7 | 1.34 |
| Justin Speier | Phi | mr | 34 | 3 | 2 | 1 | 12 | 3 | 0 | 2 | 3 | 7.2 | 1.9 | 10.8 | 10.1 | 1.7 | 5.4 | 1.01 |
| Ryan Speier | Min | mr | 28 | 1 | 0 | 0 | 2 | 2 | 1 | 0 | 1 | 6.9 | 2.1 | 9.6 | 5.7 | 0.0 | 2.7 | 1.00 |
| Russ Springer | Hou | mr | 39 | 2 | 4 | 2 | 6 | 2 | 0 | 2 | 8 | 7.2 | 3.0 | 10.7 | 8.9 | 0.5 | 2.9 | 1.14 |
| Chris Spurling | NYY | mr | 31 | 1 | 1 | 0 | 4 | 6 | 0 | 0 | 3 | 10.7 | 2.2 | 13.6 | 5.1 | 0.7 | 2.3 | 1.44 |
| Jason Stanford* | Was | mr | 31 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 13.0 | 2.0 | 16.0 | 6.0 | 0.0 | 3.0 | 1.67 |
| Mike Stanton* | Tor | mr | 41 | 1 | 0 | 4 | 2 | 1 | 0 | 0 | 4 | 13.0 | 3.5 | 16.8 | 6.6 | 1.3 | 1.9 | 1.84 |
| Tim Stauffer | KC | sp | 26 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 25.1 | 9.6 | 38.6 | 5.8 | 5.8 | 0.6 | 3.86 |
| Mitch Stetter* | Bos | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 27.0 | 27.0 | 81.0 | 27.0 | 0.0 | 1.0 | 6.00 |
| Huston Street | Det | cl | 24 | 6 | 1 | 8 | 1 | 2 | 0 | 1 | 2 | 5.7 | 1.9 | 7.8 | 11.4 | 0.7 | 5.9 | 0.85 |
| Jeff Suppan | Tex | sp | 33 | 8 | 4 | 1 | 13 | 5 | 0 | 1 | 7 | 12.4 | 3.0 | 15.9 | 4.8 | 0.8 | 1.6 | 1.70 |
| Jon Switzer* | Was | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 1.9 | 5.8 | 1.9 | 1.9 | 1.0 | 0.64 |
| Brian Tallet* | SF | mr | 30 | 9 | 3 | 1 | 3 | 2 | 0 | 1 | 2 | 7.2 | 2.6 | 10.1 | 6.9 | 0.1 | 2.7 | 1.08 |
| Taylor Tankersley* | Bal | mr | 25 | 0 | 0 | 0 | 6 | 1 | 0 | 1 | 3 | 11.1 | 5.6 | 17.7 | 9.8 | 0.7 | 1.8 | 1.86 |
| Jack Taschner* | Cin | mr | 30 | 5 | 4 | 3 | 3 | 2 | 0 | 0 | 2 | 8.2 | 6.7 | 15.3 | 8.7 | 1.1 | 1.3 | 1.66 |
| Jordan Tata | Cle | sp | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.4 | 6.8 | 15.2 | 8.4 | 1.7 | 1.3 | 1.69 |
| Ty Taubenheim | Min | sp | 25 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 27.0 | 27.0 | 63.0 | 18.0 | 0.0 | 0.7 | 6.00 |
| Julian Tavarez | Phi | sp | 35 | 5 | 2 | 4 | 9 | 2 | 0 | 5 | 5 | 10.6 | 2.7 | 13.7 | 5.7 | 1.3 | 2.1 | 1.47 |
| Robinson Tejeda | Tex | sp | 26 | 11 | 4 | 1 | 7 | 6 | 0 | 0 | 6 | 9.7 | 5.8 | 16.2 | 7.9 | 1.8 | 1.4 | 1.72 |
| Joe Thatcher* | LAD | mr | 26 | 1 | 0 | 1 | 2 | 1 | 0 | 0 | 1 | 5.6 | 2.4 | 8.7 | 8.7 | 0.8 | 3.7 | 0.88 |
| Brad Thompson | LAD | mr | 26 | 0 | 0 | 0 | 2 | 4 | 0 | 2 | 1 | 11.3 | 3.8 | 15.7 | 3.5 | 2.0 | 0.9 | 1.68 |
| John Thomson | Col | sp | 34 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 12.1 | 2.7 | 14.8 | 5.4 | 0.0 | 2.0 | 1.65 |
| Matt Thornton* | Mil | mr | 31 | 3 | 2 | 2 | 4 | 1 | 0 | 6 | 5 | 8.9 | 2.9 | 12.2 | 8.3 | 0.4 | 2.9 | 1.31 |
| Erick Threets* | SF | mr | 26 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 7.7 | 19.3 | 27.0 | 11.6 | 0.0 | 0.6 | 3.00 |
| Mike Timlin | Mil | mr | 42 | 2 | 1 | 1 | 5 | 1 | 0 | 2 | 3 | 6.9 | 1.5 | 9.1 | 5.1 | 1.4 | 3.4 | 0.94 |
| Brett Tomko | Was | mr | 35 | 9 | 3 | 2 | 3 | 4 | 0 | 2 | 2 | 10.2 | 4.6 | 15.1 | 7.4 | 0.9 | 1.6 | 1.64 |
| Salomon Torres | Bos | mr | 36 | 3 | 0 | 5 | 4 | 3 | 0 | 3 | 4 | 7.9 | 4.2 | 12.7 | 7.4 | 1.0 | 1.7 | 1.35 |
| Josh Towers | Oak | sp | 31 | 7 | 4 | 0 | 3 | 0 | 0 | 1 | 0 | 9.5 | 2.0 | 11.6 | 6.6 | 1.2 | 3.4 | 1.27 |
| Billy Traber* | Tor | mr | 28 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 15.3 | 7.8 | 23.4 | 6.0 | 1.4 | 0.8 | 2.57 |
| Steve Trachsel | Phi | sp | 37 | 19 | 4 | 3 | 4 | 4 | 5 | 10 | 3 | 11.7 | 3.9 | 15.8 | 3.8 | 1.5 | 1.0 | 1.74 |
| Chin-hui Tsao | Pit | mr | 27 | 3 | 1 | 2 | 1 | 2 | 0 | 1 | 2 | 7.4 | 2.6 | 10.2 | 6.5 | 0.2 | 2.5 | 1.11 |
| Derrick Turnbow | ChC | mr | 30 | 3 | 3 | 3 | 1 | 9 | 0 | 1 | 1 | 5.8 | 6.8 | 12.7 | 11.6 | 0.7 | 1.7 | 1.39 |
| Jose Valverde | LAD | cl | 28 | 5 | 1 | 1 | 4 | 2 | 0 | 2 | 2 | 7.4 | 2.5 | 10.3 | 10.4 | 1.3 | 4.2 | 1.10 |
| John Van Benschoten | Pit | sp | 28 | 1 | 2 | 1 | 3 | 0 | 0 | 3 | 0 | 7.0 | 7.4 | 15.4 | 6.3 | 0.7 | 0.9 | 1.60 |
| Rick VandenHurk | ChW | sp | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 5.4 | 18.9 | 10.8 | 2.7 | 2.0 | 2.10 |
| Claudio Vargas | Oak | sp | 30 | 3 | 4 | 4 | 7 | 3 | 0 | 0 | 8 | 10.8 | 3.9 | 15.2 | 6.9 | 1.4 | 1.8 | 1.64 |
| Javier Vazquez | Cle | sp | 31 | 8 | 1 | 0 | 8 | 1 | 0 | 5 | 5 | 7.4 | 1.9 | 9.6 | 9.5 | 1.5 | 5.0 | 1.03 |
| Jose Veras | Det | mr | 27 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 0 | 7.5 | 9.0 | 16.5 | 6.0 | 0.0 | 0.7 | 1.83 |
| Justin Verlander | Tor | sp | 25 | 5 | 1 | 1 | 20 | 23 | 1 | 2 | 8 | 8.0 | 3.3 | 12.1 | 7.7 | 1.4 | 2.3 | 1.26 |
| Carlos Villanueva | LAD | mr | 24 | 4 | 1 | 4 | 2 | 1 | 0 | 5 | 5 | 7.7 | 4.9 | 12.8 | 6.7 | 1.3 | 1.4 | 1.40 |
| Oscar Villarreal | Oak | mr | 26 | 7 | 1 | 6 | 4 | 13 | 0 | 1 | 6 | 8.7 | 3.5 | 12.5 | 6.6 | 0.6 | 1.9 | 1.36 |
| Ron Villone* | StL | mr | 38 | 1 | 1 | 1 | 3 | 4 | 0 | 0 | 2 | 6.0 | 1.2 | 7.8 | 6.8 | 0.6 | 5.5 | 0.80 |
| Luis Vizcaino | Hou | mr | 33 | 7 | 2 | 4 | 2 | 0 | 0 | 2 | 2 | 7.3 | 3.6 | 11.2 | 6.7 | 0.9 | 1.9 | 1.22 |
| Edinson Volquez | Ari | sp | 24 | 1 | 1 | 0 | 6 | 2 | 0 | 2 | 2 | 8.5 | 3.8 | 13.3 | 7.7 | 1.8 | 2.0 | 1.36 |
| Billy Wagner* | ChW | cl | 36 | 4 | 2 | 0 | 3 | 2 | 0 | 3 | 2 | 6.5 | 3.3 | 10.2 | 12.4 | 0.7 | 3.7 | 1.09 |
| Adam Wainwright | ChC | sp | 26 | 10 | 6 | 6 | 16 | 3 | 0 | 8 | 7 | 8.1 | 2.9 | 11.7 | 6.3 | 0.4 | 2.2 | 1.22 |
| Tim Wakefield | Det | sp | 41 | 16 | 3 | 0 | 4 | 14 | 0 | 3 | 3 | 9.4 | 3.1 | 12.7 | 6.2 | 1.3 | 2.0 | 1.39 |
| Jamie Walker* | Atl | mr | 36 | 6 | 1 | 2 | 3 | 2 | 0 | 2 | 1 | 7.6 | 1.8 | 9.7 | 7.1 | 0.7 | 4.0 | 1.05 |
| Tyler Walker | Pit | mr | 32 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 12.9 | 2.3 | 15.3 | 4.7 | 0.0 | 2.0 | 1.70 |
| Chien-Ming Wang | SD | sp | 28 | 8 | 7 | 3 | 11 | 8 | 1 | 5 | 3 | 7.3 | 1.9 | 9.6 | 4.2 | 0.2 | 2.2 | 1.02 |
| Jarrod Washburn* | NYM | sp | 33 | 9 | 5 | 11 | 5 | 1 | 2 | 4 | 8 | 9.9 | 3.4 | 13.6 | 5.0 | 1.0 | 1.5 | 1.48 |
| Ehren Wassermann | Col | mr | 27 | 3 | 1 | 5 | 7 | 2 | 0 | 2 | 0 | 11.1 | 2.1 | 14.8 | 6.4 | 0.9 | 3.0 | 1.48 |
| David Weathers | Cle | cl | 38 | 1 | 2 | 1 | 6 | 0 | 0 | 5 | 1 | 6.1 | 4.2 | 11.0 | 5.1 | 0.7 | 1.2 | 1.14 |
| Jeff Weaver | Col | sp | 31 | 13 | 7 | 6 | 10 | 3 | 1 | 6 | 10 | 11.4 | 1.7 | 13.6 | 5.0 | 1.6 | 2.9 | 1.46 |
| Jered Weaver | Cin | sp | 25 | 22 | 4 | 1 | 2 | 4 | 0 | 5 | 3 | 9.6 | 2.5 | 12.1 | 7.0 | 1.3 | 2.8 | 1.34 |
| Brandon Webb | Sea | sp | 29 | 12 | 1 | 3 | 6 | 2 | 0 | 4 | 2 | 7.9 | 2.7 | 10.8 | 7.9 | 0.4 | 2.9 | 1.18 |
| Todd Wellemeyer | Det | mr | 29 | 8 | 4 | 6 | 2 | 6 | 0 | 0 | 4 | 9.2 | 4.7 | 14.1 | 7.8 | 1.5 | 1.7 | 1.55 |
| David Wells* | NYY | sp | 45 | 6 | 2 | 1 | 5 | 0 | 0 | 5 | 3 | 12.7 | 3.0 | 15.9 | 5.7 | 0.9 | 1.9 | 1.74 |
| Kip Wells | Tex | sp | 31 | 13 | 3 | 0 | 11 | 6 | 1 | 1 | 4 | 11.1 | 4.6 | 16.3 | 7.2 | 1.1 | 1.6 | 1.74 |
| Jake Westbrook | Was | sp | 30 | 12 | 3 | 6 | 3 | 6 | 0 | 5 | 7 | 8.8 | 3.1 | 12.1 | 4.8 | 0.7 | 1.6 | 1.32 |
| Dan Wheeler | Cle | mr | 30 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 2 | 11.7 | 2.3 | 14.5 | 10.2 | 2.9 | 4.5 | 1.55 |
| Bob Wickman | Tex | cl | 39 | 5 | 2 | 1 | 2 | 3 | 2 | 4 | 1 | 11.0 | 5.2 | 16.9 | 7.1 | 0.9 | 1.4 | 1.81 |
| Todd Williams | Mil | mr | 37 | 3 | 0 | 4 | 3 | 1 | 0 | 1 | 1 | 13.2 | 2.9 | 17.0 | 6.1 | 1.0 | 2.1 | 1.79 |
| Woody Williams | KC | sp | 41 | 9 | 4 | 1 | 17 | 1 | 4 | 6 | 6 | 8.9 | 2.9 | 12.5 | 5.2 | 1.2 | 1.8 | 1.31 |
| Scott Williamson | Tam | mr | 32 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7.1 | 8.5 | 15.6 | 8.5 | 1.4 | 1.0 | 1.74 |
| Dontrelle Willis* | SF | sp | 26 | 4 | 4 | 3 | 9 | 6 | 0 | 9 | 8 | 10.7 | 4.7 | 15.8 | 7.1 | 1.4 | 1.5 | 1.71 |
| Brian Wilson | Was | cl | 26 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.9 | 1.3 | 6.6 | 7.1 | 0.0 | 5.3 | 0.69 |
| C.J. Wilson* | Pit | mr | 27 | 4 | 3 | 4 | 3 | 7 | 0 | 5 | 2 | 8.1 | 3.9 | 12.4 | 6.8 | 0.7 | 1.7 | 1.34 |
| Matt Wise | SF | mr | 32 | 2 | 0 | 0 | 1 | 0 | 0 | 5 | 2 | 10.1 | 3.3 | 13.6 | 7.7 | 0.5 | 2.3 | 1.49 |
| Randy Wolf* | Bos | sp | 31 | 8 | 3 | 0 | 2 | 5 | 0 | 0 | 2 | 11.5 | 2.9 | 14.6 | 8.8 | 1.0 | 3.0 | 1.61 |
| Brian Wolfe | StL | mr | 27 | 5 | 0 | 9 | 1 | 1 | 0 | 1 | 0 | 6.7 | 3.1 | 10.0 | 4.9 | 0.3 | 1.5 | 1.10 |
| Kerry Wood | Mil | mr | 31 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 5.3 | 4.9 | 10.3 | 8.7 | 0.0 | 1.8 | 1.14 |
| Jamey Wright | ChC | mr | 33 | 4 | 1 | 1 | 8 | 3 | 0 | 3 | 1 | 7.9 | 3.1 | 12.0 | 4.0 | 1.0 | 1.3 | 1.22 |
| Michael Wuertz | NYY | mr | 29 | 2 | 3 | 0 | 0 | 2 | 0 | 2 | 3 | 8.9 | 4.0 | 13.0 | 10.5 | 1.2 | 2.6 | 1.44 |
| Tyler Yates | NYM | mr | 30 | 6 | 5 | 15 | 7 | 1 | 0 | 3 | 3 | 9.4 | 3.9 | 13.9 | 9.4 | 1.3 | 2.4 | 1.48 |
| Shane Youman* | StL | sp | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 0.0 | 7.7 | 0.0 | 0.0 | 0.0 | 0.86 |
| Chris Young | Sea | sp | 29 | 19 | 2 | 2 | 7 | 6 | 5 | 0 | 8 | 7.4 | 4.4 | 12.2 | 8.6 | 0.9 | 1.9 | 1.31 |
| Carlos Zambrano | Det | sp | 27 | 6 | 2 | 11 | 10 | 4 | 0 | 5 | 8 | 7.8 | 5.1 | 13.3 | 7.9 | 1.0 | 1.5 | 1.44 |
| Victor Zambrano | Atl | mr | 32 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 12.0 | 3.0 | 18.0 | 9.0 | 6.0 | 3.0 | 1.67 |
| Barry Zito* | Ari | sp | 30 | 2 | 1 | 1 | 2 | 5 | 0 | 5 | 7 | 8.4 | 3.5 | 12.0 | 6.2 | 1.5 | 1.8 | 1.33 |
| Joel Zumaya | SD | mr | 23 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 11.6 | 3.9 | 15.4 | 7.7 | 0.0 | 2.0 | 1.71 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| David Aardsma | Min | mr | 26 | 1.500 | 4 | .500 | 6 | 1.000 | 6 | 1.000 | 3.0 | 27.0 | 24.30 | 25.51 |
| Jeremy Accardo | Ari | cl | 26 | .668 | 244 | .336 | 140 | .388 | 144 | .399 | 38.6 | 4.1 | 3.66 | 3.58 |
| Manny Acosta | StL | mr | 27 | .582 | 66 | .212 | 40 | .377 | 41 | .387 | 7.2 | 2.3 | 2.11 | 2.38 |
| Jeremy Affeldt* | Tam | mr | 29 | .612 | 278 | .263 | 163 | .377 | 169 | .391 | 36.5 | 3.2 | 2.87 | 2.73 |
| Jonathan Albaladejo | StL | mr | 25 | .599 | 72 | .194 | 41 | .376 | 43 | .394 | 7.9 | 2.5 | 2.34 | 2.60 |
| Matt Albers | Tam | sp | 25 | .861 | 374 | .342 | 278 | .525 | 284 | .536 | 90.2 | 7.1 | 6.54 | 6.37 |
| Greg Aquino | Cin | mr | 30 | .638 | 34 | .265 | 22 | .400 | 22 | .400 | 4.6 | 2.9 | 2.58 | 2.67 |
| Tony Armas | Col | mr | 30 | .840 | 358 | .296 | 284 | .518 | 296 | .540 | 87.7 | 6.6 | 5.90 | 5.68 |
| Bronson Arroyo | Atl | sp | 31 | .708 | 761 | .304 | 438 | .416 | 450 | .427 | 120.3 | 4.4 | 3.97 | 3.76 |
| Jose Ascanio | Ari | mr | 23 | 1.306 | 17 | .353 | 32 | .914 | 32 | .914 | 11.1 | 13.6 | 12.22 | 12.29 |
| Luis Ayala | LAD | mr | 30 | .635 | 94 | .266 | 48 | .378 | 49 | .386 | 12.3 | 3.7 | 3.40 | 3.37 |
| Brandon Backe | NYY | sp | 30 | .642 | 131 | .229 | 65 | .367 | 72 | .407 | 15.4 | 3.2 | 2.96 | 3.62 |
| Mike Bacsik* | Atl | sp | 30 | .825 | 482 | .297 | 292 | .491 | 298 | .501 | 82.6 | 5.4 | 4.88 | 5.30 |
| Cha Seung Baek | StL | sp | 28 | .818 | 320 | .338 | 203 | .486 | 206 | .493 | 63.4 | 6.0 | 5.52 | 4.92 |
| Danys Baez | Pit | mr | 30 | .837 | 302 | .298 | 207 | .498 | 218 | .524 | 64.7 | 6.4 | 5.82 | 5.92 |
| Homer Bailey | LAD | sp | 22 | .743 | 149 | .255 | 114 | .481 | 116 | .489 | 28.0 | 4.9 | 4.45 | 4.83 |
| Scott Baker | NYM | sp | 26 | .659 | 495 | .277 | 254 | .391 | 258 | .398 | 64.0 | 3.6 | 3.27 | 2.81 |
| John Bale* | LAD | mr | 34 | .657 | 8 | .375 | 5 | .385 | 5 | .385 | 1.1 | 3.2 | 2.92 | 4.60 |
| Josh Banks | SF | mr | 25 | .400 | 5 | .200 | 1 | .200 | 1 | .200 | 0.2 | 1.4 | 1.62 | 1.51 |
| Brian Bannister | ChW | sp | 27 | .741 | 581 | .281 | 338 | .455 | 343 | .462 | 86.5 | 4.4 | 4.01 | 3.90 |
| Daniel Barone | Ari | mr | 25 | .977 | 9 | .000 | 9 | .750 | 9 | .750 | 2.1 | 6.2 | 5.58 | 5.20 |
| Miguel Batista | Was | sp | 37 | .754 | 537 | .304 | 358 | .455 | 370 | .470 | 99.3 | 5.0 | 4.54 | 4.32 |
| Yorman Bazardo | LAA | mr | 23 | .575 | 62 | .194 | 26 | .310 | 32 | .381 | 6.1 | 2.6 | 2.41 | 2.56 |
| Josh Beckett | Flo | sp | 28 | .693 | 611 | .295 | 376 | .421 | 389 | .435 | 96.9 | 4.0 | 3.63 | 3.10 |
| Erik Bedard* | Tor | sp | 29 | .652 | 601 | .318 | 411 | .403 | 417 | .409 | 98.4 | 3.6 | 3.20 | 3.07 |
| Joe Beimel* | ChC | mr | 31 | .668 | 289 | .294 | 146 | .395 | 147 | .397 | 34.5 | 3.4 | 3.10 | 3.25 |
| Matt Belisle | NYY | sp | 28 | .898 | 545 | .350 | 417 | .549 | 423 | .557 | 132.4 | 7.2 | 6.50 | 6.76 |
| Heath Bell | Ari | mr | 30 | .561 | 277 | .271 | 137 | .332 | 140 | .339 | 30.6 | 2.6 | 2.39 | 2.06 |
| Armando Benitez | Tam | mr | 35 | .655 | 41 | .268 | 28 | .424 | 28 | .424 | 6.2 | 3.3 | 3.00 | 2.45 |
| Jeff Bennett | Oak | sp | 28 | .561 | 56 | .321 | 25 | .316 | 25 | .316 | 5.9 | 2.8 | 2.57 | 2.66 |
| Joaquin Benoit | Oak | mr | 30 | .592 | 299 | .281 | 159 | .354 | 161 | .359 | 37.9 | 3.1 | 2.80 | 2.43 |
| Jason Bergmann | Cin | sp | 26 | .730 | 423 | .253 | 303 | .471 | 305 | .474 | 78.9 | 4.8 | 4.31 | 4.04 |
| Rafael Betancourt | ChW | mr | 33 | .427 | 261 | .211 | 99 | .261 | 99 | .261 | 15.2 | 1.3 | 1.15 | 0.90 |
| Chad Billingsley | Ari | mr | 23 | .792 | 511 | .309 | 387 | .494 | 390 | .497 | 104.2 | 5.2 | 4.71 | 4.97 |
| Kurt Birkins* | LAA | mr | 27 | .955 | 8 | .500 | 6 | .545 | 6 | .545 | 1.9 | 7.4 | 6.64 | 8.25 |
| Travis Blackley* | Cin | sp | 25 | 1.081 | 47 | .298 | 46 | .687 | 46 | .687 | 13.9 | 8.7 | 7.87 | 9.23 |
| Joe Blanton | NYY | sp | 27 | .759 | 711 | .336 | 409 | .445 | 417 | .453 | 117.6 | 4.9 | 4.53 | 4.39 |
| Jeremy Bonderman | LAD | sp | 25 | .821 | 595 | .334 | 414 | .498 | 421 | .506 | 124.1 | 5.8 | 5.29 | 5.10 |
| Boof Bonser | LAA | sp | 26 | .670 | 235 | .272 | 133 | .413 | 134 | .416 | 33.4 | 3.9 | 3.58 | 3.28 |
| Chris Booker | Phi | mr | 31 | 1.409 | 24 | .458 | 28 | .800 | 28 | .800 | 13.4 | 25.9 | 23.31 | 23.61 |
| Chris Bootcheck | Min | mr | 29 | .950 | 105 | .381 | 86 | .562 | 90 | .588 | 29.7 | 8.1 | 7.13 | 7.00 |
| Dave Borkowski | Oak | mr | 31 | .815 | 115 | .313 | 86 | .506 | 88 | .518 | 24.3 | 5.8 | 5.13 | 5.27 |
| Joe Borowski | Sea | cl | 37 | .723 | 262 | .324 | 155 | .429 | 158 | .438 | 44.3 | 4.7 | 4.20 | 3.81 |
| Micah Bowie* | SD | mr | 33 | .654 | 145 | .276 | 84 | .398 | 85 | .403 | 20.1 | 3.7 | 3.36 | 3.63 |
| Blaine Boyer | Oak | mr | 26 | .588 | 16 | .313 | 5 | .294 | 5 | .294 | 1.5 | 3.3 | 2.55 | 2.61 |
| Dallas Braden* | Atl | sp | 24 | .874 | 218 | .303 | 171 | .550 | 174 | .559 | 51.6 | 6.6 | 6.00 | 5.79 |
| Chad Bradford | Ari | mr | 33 | .842 | 249 | .357 | 152 | .472 | 160 | .497 | 48.0 | 6.1 | 5.52 | 5.68 |
| Ryan Braun | NYY | mr | 27 | .888 | 160 | .325 | 125 | .546 | 127 | .555 | 40.2 | 7.5 | 6.83 | 7.08 |
| Chris Britton | Cin | mr | 25 | .380 | 70 | .114 | 22 | .256 | 22 | .256 | 3.1 | 1.2 | 1.10 | 1.06 |
| Lance Broadway | Flo | mr | 24 | .565 | 39 | .282 | 20 | .345 | 20 | .345 | 4.3 | 2.9 | 2.71 | 2.92 |
| Doug Brocail | Was | mr | 41 | .581 | 290 | .214 | 131 | .359 | 133 | .364 | 27.9 | 2.7 | 2.44 | 2.03 |
| Andrew Brown | Tam | mr | 27 | .646 | 177 | .282 | 115 | .405 | 118 | .415 | 27.0 | 3.5 | 3.16 | 2.64 |
| Jonathan Broxton | Flo | mr | 24 | .578 | 219 | .306 | 132 | .356 | 132 | .356 | 28.1 | 2.7 | 2.42 | 2.17 |
| Brian Bruney | Sea | mr | 26 | .765 | 155 | .297 | 117 | .468 | 121 | .484 | 32.6 | 5.3 | 4.85 | 4.80 |
| Clay Buchholz | Det | sp | 23 | .549 | 73 | .219 | 42 | .350 | 44 | .367 | 8.8 | 2.8 | 2.51 | 2.72 |
| Taylor Buchholz | Min | mr | 26 | .698 | 402 | .318 | 220 | .415 | 221 | .417 | 57.1 | 4.0 | 3.68 | 3.59 |
| Billy Buckner | Tex | sp | 24 | .809 | 128 | .227 | 93 | .528 | 94 | .534 | 23.8 | 5.1 | 4.77 | 4.52 |
| Mark Buehrle* | LAA | sp | 29 | .797 | 642 | .312 | 404 | .484 | 410 | .491 | 120.3 | 5.7 | 5.13 | 4.94 |
| Jason Bulger | ChC | mr | 29 | .439 | 45 | .222 | 15 | .254 | 15 | .254 | 2.6 | 1.5 | 1.44 | 1.63 |
| Bryan Bullington | Pit | sp | 27 | .871 | 103 | .320 | 66 | .524 | 66 | .524 | 22.1 | 7.4 | 6.81 | 7.21 |
| Ambiorix Burgos | Bos | mr | 24 | .411 | 82 | .134 | 40 | .288 | 40 | .288 | 6.0 | 1.5 | 1.35 | 1.15 |
| A.J. Burnett | Col | sp | 31 | .641 | 476 | .298 | 302 | .386 | 313 | .400 | 71.4 | 3.3 | 2.98 | 2.91 |
| Brian Burres* | Was | mr | 27 | .756 | 409 | .276 | 283 | .466 | 290 | .478 | 76.9 | 5.1 | 4.65 | 4.58 |
| Jared Burton | Bos | mr | 27 | .561 | 250 | .240 | 127 | .342 | 130 | .350 | 28.5 | 2.8 | 2.61 | 2.66 |
| Dave Bush | KC | sp | 28 | .782 | 650 | .326 | 434 | .471 | 448 | .486 | 131.2 | 5.8 | 5.24 | 4.87 |
| Paul Byrd | Pit | sp | 37 | .788 | 589 | .299 | 359 | .476 | 366 | .485 | 106.9 | 5.5 | 4.95 | 4.39 |
| Tim Byrdak* | Col | mr | 34 | .657 | 198 | .278 | 129 | .413 | 131 | .420 | 28.1 | 3.3 | 2.96 | 2.98 |
| Daniel Cabrera | Mil | sp | 27 | .783 | 631 | .304 | 455 | .477 | 471 | .494 | 129.7 | 5.4 | 4.91 | 4.77 |
| Fernando Cabrera | StL | mr | 26 | .561 | 9 | .333 | 6 | .353 | 6 | .353 | 1.3 | 3.0 | 2.69 | 2.40 |
| Matt Cain | SF | sp | 23 | .739 | 575 | .323 | 397 | .448 | 406 | .458 | 111.4 | 5.0 | 4.53 | 4.46 |
| Kiko Calero | ChW | mr | 33 | .760 | 38 | .263 | 26 | .491 | 26 | .491 | 6.7 | 4.7 | 4.63 | 4.22 |
| Kevin Cameron | Det | mr | 28 | .773 | 261 | .379 | 190 | .447 | 195 | .459 | 63.5 | 6.7 | 5.99 | 6.21 |
| Shawn Camp | Hou | mr | 32 | 1.141 | 214 | .500 | 207 | .679 | 210 | .689 | 84.6 | 13.1 | 11.89 | 11.90 |
| Jose Capellan | Hou | mr | 27 | .671 | 111 | .243 | 62 | .425 | 62 | .425 | 13.9 | 3.4 | 3.10 | 2.71 |
| Matt Capps | Was | mr | 24 | .572 | 175 | .251 | 83 | .337 | 86 | .350 | 19.5 | 2.9 | 2.61 | 2.21 |
| Chris Capuano* | NYY | sp | 29 | .808 | 494 | .356 | 356 | .489 | 360 | .495 | 107.4 | 6.1 | 5.48 | 5.59 |
| Buddy Carlyle | Atl | sp | 30 | .775 | 377 | .289 | 251 | .485 | 255 | .492 | 66.3 | 4.9 | 4.43 | 4.19 |
| Fausto Carmona | SD | sp | 27 | .645 | 679 | .265 | 340 | .377 | 356 | .394 | 78.6 | 3.2 | 2.85 | 2.94 |
| Chris Carpenter | Min | sp | 33 | .767 | 33 | .333 | 19 | .442 | 20 | .465 | 6.1 | 6.1 | 5.67 | 5.27 |
| Marcos Carvajal | Oak | mr | 23 | 1.000 | 1 | 1.000 | 1 | .500 | 1 | .500 | 0.5 | 13.5 | 12.15 | 14.52 |
| Santiago Casilla | Col | mr | 27 | .814 | 173 | .295 | 153 | .522 | 155 | .529 | 44.1 | 6.0 | 5.28 | 5.10 |
| Jack Cassel | Tex | sp | 27 | .865 | 102 | .392 | 67 | .493 | 68 | .500 | 22.1 | 7.2 | 6.25 | 7.38 |
| Fabio Castro* | ChW | mr | 23 | .935 | 14 | .357 | 15 | .600 | 15 | .600 | 4.3 | 9.8 | 8.78 | 12.83 |
| Gustavo Chacin* | LAD | sp | 27 | .789 | 122 | .279 | 70 | .458 | 74 | .484 | 19.9 | 4.9 | 4.47 | 4.45 |
| Shawn Chacon | Cin | mr | 30 | .825 | 313 | .294 | 246 | .504 | 256 | .525 | 69.6 | 5.8 | 5.32 | 5.48 |
| Joba Chamberlain | Oak | mr | 22 | .626 | 67 | .269 | 53 | .402 | 55 | .417 | 12.1 | 3.4 | 3.07 | 2.84 |
| Rocky Cherry | Was | mr | 28 | .628 | 63 | .222 | 36 | .396 | 38 | .418 | 7.6 | 3.0 | 2.75 | 2.52 |
| Matt Chico* | Det | sp | 25 | .836 | 504 | .321 | 354 | .507 | 358 | .513 | 111.2 | 6.6 | 5.90 | 5.85 |
| Vinnie Chulk | KC | mr | 29 | .671 | 337 | .291 | 200 | .411 | 203 | .417 | 49.2 | 3.8 | 3.43 | 3.07 |
| Roger Clemens | SD | sp | 45 | .692 | 410 | .283 | 222 | .407 | 229 | .420 | 59.9 | 4.2 | 3.86 | 3.72 |
| Tyler Clippard | Ari | sp | 23 | .724 | 96 | .219 | 62 | .459 | 64 | .474 | 15.5 | 4.3 | 3.84 | 3.69 |
| Todd Coffey | SF | mr | 27 | 1.001 | 152 | .421 | 117 | .563 | 121 | .582 | 44.2 | 9.6 | 8.59 | 9.38 |
| Jesus Colome | Pit | mr | 30 | .813 | 382 | .351 | 250 | .474 | 255 | .484 | 79.2 | 6.3 | 5.77 | 5.98 |
| Bartolo Colon | Tor | sp | 35 | .926 | 545 | .374 | 434 | .556 | 448 | .574 | 146.3 | 7.9 | 7.35 | 7.39 |
| Jose Contreras | Bal | sp | 36 | .863 | 576 | .332 | 409 | .520 | 418 | .531 | 133.1 | 7.0 | 6.38 | 6.30 |
| Aaron Cook | Atl | sp | 29 | .708 | 766 | .272 | 387 | .418 | 395 | .427 | 99.8 | 4.0 | 3.71 | 3.86 |
| Chad Cordero | SF | cl | 26 | .709 | 202 | .322 | 128 | .422 | 129 | .426 | 35.2 | 4.6 | 4.09 | 4.09 |
| Francisco Cordero | Oak | cl | 33 | .587 | 159 | .321 | 100 | .361 | 101 | .365 | 22.2 | 3.0 | 2.72 | 2.58 |
| Bryan Corey | Tam | mr | 34 | .815 | 38 | .342 | 30 | .508 | 30 | .508 | 7.7 | 5.2 | 4.68 | 5.79 |
| Lance Cormier | Flo | sp | 27 | .959 | 170 | .306 | 149 | .618 | 150 | .622 | 47.4 | 8.3 | 7.63 | 7.47 |
| Manny Corpas | Sea | mr | 25 | .460 | 205 | .205 | 77 | .275 | 79 | .282 | 13.2 | 1.6 | 1.43 | 1.39 |
| Kevin Correia | LAA | mr | 27 | .654 | 180 | .256 | 103 | .410 | 103 | .410 | 23.2 | 3.3 | 3.00 | 2.71 |
| Neal Cotts* | Tam | mr | 28 | .625 | 83 | .277 | 50 | .382 | 51 | .389 | 12.0 | 3.5 | 3.09 | 3.20 |
| Jon Coutlangus* | Det | mr | 27 | .867 | 159 | .371 | 144 | .533 | 146 | .541 | 44.1 | 7.3 | 6.57 | 7.63 |
| Juan Cruz | Det | mr | 29 | .623 | 180 | .272 | 143 | .403 | 146 | .411 | 32.7 | 3.5 | 3.12 | 2.65 |
| John Danks* | Col | sp | 23 | .958 | 534 | .339 | 466 | .604 | 471 | .610 | 150.4 | 8.1 | 7.22 | 6.99 |
| Kyle Davies | Cin | sp | 24 | .940 | 398 | .307 | 349 | .597 | 353 | .603 | 113.8 | 8.2 | 7.38 | 6.92 |
| Doug Davis* | StL | sp | 32 | .738 | 623 | .313 | 389 | .438 | 394 | .444 | 107.3 | 4.8 | 4.35 | 4.46 |
| Jorge De La Rosa* | Bos | sp | 27 | .794 | 382 | .325 | 246 | .482 | 248 | .486 | 73.3 | 5.8 | 5.30 | 5.25 |
| Manny Delcarmen | Cle | mr | 26 | .646 | 186 | .258 | 114 | .399 | 116 | .406 | 27.4 | 3.6 | 3.22 | 3.23 |
| Ryan Dempster | Min | cl | 31 | .598 | 229 | .227 | 121 | .369 | 125 | .381 | 24.9 | 2.7 | 2.44 | 2.49 |
| Julio DePaula | NYY | mr | 25 | 1.123 | 77 | .364 | 65 | .650 | 69 | .690 | 25.6 | 11.9 | 10.37 | 11.11 |
| Matt DeSalvo | Phi | sp | 27 | 1.041 | 156 | .378 | 122 | .622 | 125 | .638 | 46.6 | 11.3 | 10.29 | 9.47 |
| Ross Detwiler* | Tex | mr | 22 | .286 | 7 | .143 | 1 | .143 | 1 | .143 | 0.1 | 0.6 | 0.58 | 0.54 |
| Joey Devine | Hou | mr | 24 | .972 | 45 | .422 | 43 | .558 | 44 | .571 | 15.7 | 10.6 | 10.05 | 12.52 |
| Lenny DiNardo* | Tam | sp | 28 | .744 | 524 | .290 | 313 | .449 | 319 | .458 | 80.6 | 4.5 | 4.07 | 4.54 |
| Scott Dohmann | KC | mr | 30 | .610 | 176 | .244 | 100 | .370 | 104 | .385 | 21.4 | 2.8 | 2.58 | 2.77 |
| Brendan Donnelly | Tor | mr | 36 | .623 | 200 | .225 | 99 | .374 | 105 | .396 | 24.3 | 3.4 | 3.11 | 2.62 |
| Octavio Dotel | Ari | cl | 34 | 1.053 | 12 | .417 | 13 | .684 | 13 | .684 | 5.2 | 11.6 | 10.47 | 9.97 |
| Scott Downs* | LAA | mr | 32 | .624 | 171 | .327 | 96 | .365 | 97 | .369 | 23.5 | 3.4 | 3.09 | 3.31 |
| Brandon Duckworth | Was | mr | 32 | .613 | 161 | .248 | 84 | .378 | 84 | .378 | 17.5 | 2.9 | 2.63 | 2.92 |
| Zach Duke* | Oak | sp | 25 | .952 | 466 | .373 | 324 | .563 | 329 | .572 | 111.8 | 8.3 | 7.55 | 7.68 |
| Phil Dumatrait* | NYM | sp | 26 | 1.139 | 36 | .472 | 33 | .660 | 33 | .660 | 14.3 | 16.7 | 14.45 | 15.28 |
| Chad Durbin | Bos | sp | 30 | .752 | 496 | .272 | 309 | .452 | 321 | .470 | 88.8 | 5.2 | 4.79 | 4.86 |
| J.D. Durbin | SF | sp | 26 | 1.010 | 110 | .436 | 89 | .589 | 90 | .596 | 30.9 | 9.5 | 8.54 | 10.14 |
| Adam Eaton | Bal | sp | 30 | .945 | 361 | .316 | 300 | .583 | 307 | .596 | 96.8 | 8.1 | 7.44 | 7.88 |
| Scott Elarton | Mil | sp | 32 | 1.122 | 129 | .333 | 119 | .680 | 125 | .714 | 45.5 | 11.9 | 10.53 | 10.23 |
| Alan Embree* | Bos | cl | 38 | .773 | 281 | .324 | 178 | .471 | 179 | .474 | 49.6 | 5.0 | 4.62 | 4.44 |
| Kelvim Escobar | Bal | sp | 32 | .552 | 656 | .242 | 318 | .343 | 319 | .344 | 60.5 | 2.3 | 2.05 | 1.92 |
| Dana Eveland* | KC | mr | 24 | 1.181 | 25 | .440 | 24 | .686 | 24 | .686 | 10.6 | 16.8 | 14.30 | 14.26 |
| Scott Eyre* | Was | mr | 36 | .803 | 134 | .313 | 99 | .488 | 100 | .493 | 28.7 | 6.1 | 5.41 | 5.07 |
| Kyle Farnsworth | Cle | mr | 32 | .723 | 261 | .272 | 160 | .437 | 164 | .448 | 44.6 | 4.7 | 4.28 | 4.11 |
| Scott Feldman | Tex | mr | 25 | .839 | 196 | .306 | 156 | .513 | 162 | .533 | 46.2 | 6.5 | 5.88 | 6.08 |
| Pedro Feliciano* | Oak | mr | 31 | .761 | 254 | .319 | 185 | .467 | 190 | .480 | 48.7 | 4.8 | 4.38 | 4.40 |
| Randy Flores* | Ari | mr | 32 | .798 | 119 | .370 | 68 | .439 | 69 | .445 | 21.4 | 5.6 | 4.86 | 5.03 |
| Ron Flores* | NYY | mr | 28 | .625 | 5 | .400 | 3 | .375 | 3 | .375 | 0.8 | 3.4 | 3.04 | 1.95 |
| Gavin Floyd | LAA | sp | 25 | .925 | 58 | .293 | 54 | .593 | 56 | .615 | 16.4 | 7.3 | 6.55 | 6.50 |
| Josh Fogg | Ari | sp | 31 | .884 | 311 | .315 | 233 | .553 | 238 | .565 | 70.1 | 6.6 | 6.04 | 5.25 |
| Casey Fossum* | Pit | mr | 30 | .981 | 307 | .404 | 235 | .579 | 240 | .591 | 87.1 | 9.5 | 8.57 | 8.69 |
| Jeff Francis* | LAD | sp | 27 | .718 | 699 | .329 | 391 | .412 | 397 | .418 | 108.9 | 4.4 | 3.97 | 4.03 |
| Frank Francisco | Min | mr | 28 | .655 | 164 | .280 | 92 | .398 | 94 | .407 | 23.1 | 3.9 | 3.53 | 3.41 |
| Ryan Franklin | ChC | mr | 35 | .569 | 226 | .212 | 100 | .344 | 104 | .357 | 21.0 | 2.5 | 2.25 | 1.88 |
| Jason Frasor | StL | mr | 30 | .547 | 196 | .281 | 96 | .324 | 97 | .328 | 21.4 | 2.6 | 2.39 | 2.05 |
| Brian Fuentes* | Tor | cl | 32 | .643 | 187 | .289 | 114 | .383 | 119 | .399 | 29.5 | 3.9 | 3.60 | 3.58 |
| Aaron Fultz* | Tex | mr | 34 | .767 | 220 | .318 | 160 | .473 | 162 | .479 | 46.0 | 5.6 | 5.06 | 4.69 |
| Kason Gabbard* | LAD | sp | 26 | .693 | 312 | .234 | 199 | .428 | 211 | .454 | 48.6 | 3.9 | 3.57 | 3.63 |
| Eric Gagne | NYM | cl | 32 | .666 | 224 | .286 | 133 | .404 | 135 | .410 | 32.4 | 3.7 | 3.40 | 3.26 |
| Armando Galarraga | KC | mr | 26 | .773 | 274 | .230 | 215 | .508 | 217 | .513 | 57.8 | 5.5 | 5.07 | 5.15 |
| Sean Gallagher | Tex | mr | 22 | .883 | 11 | .273 | 10 | .500 | 12 | .600 | 3.0 | 8.2 | 7.39 | 11.07 |
| Yovani Gallardo | StL | sp | 22 | .742 | 395 | .304 | 261 | .451 | 266 | .459 | 69.6 | 4.6 | 4.15 | 4.10 |
| Freddy Garcia | Det | sp | 32 | .835 | 43 | .256 | 35 | .500 | 39 | .557 | 11.1 | 6.5 | 5.99 | 5.93 |
| Harvey Garcia | SF | mr | 24 | 1.250 | 0 | .000 | 4 | 1.000 | 4 | 1.000 | 1.0 | 9.0 | 8.10 | 7.45 |
| Lee Gardner | Bos | mr | 33 | .624 | 324 | .284 | 142 | .341 | 151 | .363 | 35.0 | 3.1 | 2.82 | 3.02 |
| Jon Garland | Pit | sp | 28 | .689 | 719 | .273 | 362 | .410 | 369 | .418 | 92.9 | 3.9 | 3.56 | 3.37 |
| Matt Garza | Oak | sp | 24 | .725 | 309 | .320 | 204 | .438 | 210 | .451 | 54.3 | 4.5 | 4.11 | 4.18 |
| Chad Gaudin | NYM | sp | 25 | .774 | 572 | .290 | 406 | .480 | 413 | .489 | 109.9 | 5.1 | 4.65 | 4.61 |
| Geoff Geary | Flo | mr | 31 | .811 | 328 | .345 | 202 | .452 | 217 | .485 | 63.6 | 5.8 | 5.20 | 5.47 |
| Justin Germano | StL | sp | 25 | .678 | 507 | .250 | 276 | .414 | 284 | .426 | 69.9 | 3.8 | 3.48 | 3.03 |
| Tom Glavine* | ChC | sp | 42 | .902 | 544 | .325 | 380 | .544 | 386 | .553 | 122.6 | 7.3 | 6.62 | 6.67 |
| Gary Glover | Mil | mr | 31 | .763 | 271 | .310 | 183 | .467 | 184 | .469 | 50.5 | 5.0 | 4.50 | 4.49 |
| Jimmy Gobble* | Flo | mr | 26 | 1.000 | 132 | .402 | 116 | .620 | 117 | .626 | 39.5 | 9.1 | 8.43 | 8.07 |
| Edgar Gonzalez | Col | mr | 25 | .829 | 388 | .294 | 272 | .516 | 279 | .529 | 75.9 | 5.6 | 5.08 | 4.68 |
| Mike Gonzalez* | Atl | mr | 30 | .847 | 34 | .382 | 27 | .519 | 27 | .519 | 8.2 | 7.4 | 6.41 | 6.98 |
| Tom Gordon | Phi | mr | 40 | .893 | 233 | .305 | 196 | .549 | 202 | .566 | 60.3 | 7.0 | 6.40 | 6.44 |
| Tom Gorzelanny* | Pit | sp | 25 | .786 | 636 | .314 | 410 | .471 | 418 | .480 | 120.8 | 5.5 | 5.04 | 4.74 |
| John Grabow* | Bal | mr | 29 | .733 | 276 | .333 | 175 | .438 | 177 | .442 | 48.2 | 4.9 | 4.42 | 4.99 |
| Sean Green | Min | mr | 29 | .778 | 142 | .387 | 93 | .447 | 95 | .457 | 26.6 | 5.2 | 4.55 | 5.31 |
| Kevin Gregg | Det | cl | 30 | .605 | 254 | .252 | 174 | .390 | 177 | .397 | 37.4 | 3.1 | 2.78 | 2.59 |
| Zack Greinke | LAA | mr | 24 | .742 | 568 | .319 | 379 | .459 | 383 | .464 | 102.5 | 4.7 | 4.27 | 3.83 |
| Jason Grilli | Phi | mr | 31 | .837 | 233 | .378 | 164 | .485 | 168 | .497 | 53.6 | 6.7 | 6.09 | 6.25 |
| Eddie Guardado* | Mil | mr | 37 | 1.075 | 71 | .423 | 61 | .610 | 64 | .640 | 24.2 | 11.1 | 9.79 | 9.19 |
| Matt Guerrier | Sea | mr | 29 | .711 | 218 | .298 | 130 | .414 | 138 | .439 | 35.4 | 4.3 | 3.89 | 3.90 |
| Jeremy Guthrie | Min | sp | 29 | .668 | 642 | .255 | 377 | .423 | 379 | .425 | 84.9 | 3.5 | 3.15 | 3.14 |
| Juan Gutierrez | SD | mr | 24 | .808 | 44 | .273 | 31 | .534 | 31 | .534 | 7.8 | 4.9 | 4.39 | 3.19 |
| Roy Halladay | Hou | sp | 31 | .663 | 760 | .288 | 373 | .389 | 376 | .392 | 91.2 | 3.5 | 3.19 | 3.18 |
| Cole Hamels* | Flo | sp | 24 | .666 | 508 | .280 | 322 | .408 | 334 | .423 | 80.1 | 3.8 | 3.40 | 3.08 |
| Jason Hammel | Sea | sp | 25 | .838 | 76 | .289 | 54 | .529 | 54 | .529 | 15.1 | 5.7 | 5.16 | 5.55 |
| Justin Hampson* | SD | mr | 28 | .694 | 174 | .293 | 96 | .416 | 97 | .420 | 24.6 | 4.0 | 3.62 | 3.30 |
| Joel Hanrahan | NYM | sp | 26 | 1.189 | 59 | .407 | 58 | .725 | 58 | .725 | 24.6 | 16.2 | 14.56 | 14.24 |
| Aaron Harang | Cle | sp | 30 | .694 | 691 | .302 | 429 | .421 | 439 | .430 | 112.8 | 4.2 | 3.81 | 3.64 |
| Rich Harden | Col | sp | 26 | .527 | 46 | .217 | 31 | .352 | 31 | .352 | 5.6 | 2.2 | 1.93 | 1.55 |
| Dan Haren | LAA | sp | 27 | .637 | 681 | .254 | 378 | .392 | 386 | .400 | 90.7 | 3.4 | 3.14 | 2.80 |
| Kevin Hart | LAA | mr | 25 | .327 | 33 | .121 | 13 | .236 | 13 | .236 | 1.3 | 0.8 | 0.72 | 0.88 |
| LaTroy Hawkins | Tex | mr | 35 | .736 | 219 | .292 | 127 | .444 | 128 | .448 | 34.5 | 4.6 | 4.15 | 3.94 |
| Aaron Heilman | Hou | mr | 29 | .599 | 323 | .272 | 158 | .351 | 164 | .364 | 38.5 | 3.1 | 2.82 | 2.51 |
| Mark Hendrickson* | Sea | mr | 34 | .695 | 451 | .299 | 263 | .419 | 266 | .424 | 69.3 | 4.2 | 3.83 | 3.91 |
| Sean Henn* | Flo | mr | 27 | .375 | 7 | .143 | 2 | .250 | 2 | .250 | 0.3 | 1.0 | 0.87 | 0.40 |
| Brad Hennessey | Flo | cl | 28 | .843 | 218 | .307 | 163 | .524 | 167 | .537 | 46.4 | 6.0 | 5.40 | 5.46 |
| Clay Hensley | Ari | sp | 28 | .777 | 47 | .340 | 30 | .448 | 30 | .448 | 8.4 | 4.9 | 4.42 | 5.11 |
| Matt Herges | Pit | mr | 38 | .464 | 143 | .133 | 59 | .307 | 61 | .318 | 8.7 | 1.5 | 1.33 | 1.11 |
| Felix Hernandez | Bal | sp | 22 | .769 | 626 | .356 | 423 | .459 | 428 | .465 | 119.5 | 5.1 | 4.65 | 4.94 |
| Livan Hernandez | Atl | sp | 33 | .890 | 753 | .300 | 538 | .550 | 542 | .554 | 172.8 | 7.3 | 6.63 | 6.61 |
| Orlando Hernandez | ChC | sp | 38 | .772 | 431 | .232 | 348 | .504 | 355 | .514 | 89.6 | 5.0 | 4.48 | 4.21 |
| Roberto Hernandez | Atl | mr | 43 | .969 | 196 | .367 | 147 | .559 | 154 | .586 | 53.4 | 9.0 | 7.87 | 7.61 |
| Rich Hill* | ChC | sp | 28 | .722 | 532 | .252 | 374 | .457 | 381 | .466 | 95.6 | 4.4 | 4.01 | 3.60 |
| Shawn Hill | Tam | sp | 27 | .735 | 432 | .278 | 272 | .458 | 278 | .468 | 71.4 | 4.6 | 4.17 | 3.81 |
| Jason Hirsh | Ari | sp | 26 | .903 | 322 | .273 | 267 | .583 | 270 | .590 | 76.5 | 6.6 | 5.96 | 5.49 |
| Luke Hochevar | Mil | mr | 24 | .542 | 37 | .189 | 12 | .279 | 15 | .349 | 2.9 | 2.4 | 2.27 | 2.02 |
| Jim Hoey | NYM | mr | 25 | .968 | 58 | .362 | 52 | .591 | 52 | .591 | 16.9 | 9.2 | 8.07 | 9.43 |
| Trevor Hoffman | SD | cl | 40 | .603 | 240 | .246 | 115 | .373 | 116 | .377 | 25.4 | 2.9 | 2.62 | 1.86 |
| D.J. Houlton | Flo | mr | 28 | .717 | 52 | .308 | 32 | .438 | 32 | .438 | 8.7 | 4.7 | 4.14 | 4.37 |
| J.P. Howell* | Flo | sp | 25 | .888 | 103 | .427 | 81 | .500 | 84 | .519 | 28.3 | 7.5 | 6.62 | 6.93 |
| Bob Howry | ChC | mr | 34 | .651 | 289 | .280 | 164 | .397 | 166 | .402 | 39.4 | 3.5 | 3.16 | 2.96 |
| Tim Hudson | Min | sp | 32 | .680 | 719 | .296 | 393 | .404 | 403 | .414 | 98.3 | 3.7 | 3.43 | 3.41 |
| Phil Hughes | SF | sp | 22 | .703 | 300 | .250 | 200 | .451 | 204 | .460 | 50.1 | 4.3 | 3.83 | 3.36 |
| Philip Humber | LAA | mr | 25 | .200 | 4 | .000 | 1 | .200 | 1 | .200 | 0.1 | 0.4 | 0.32 | 0.57 |
| Kei Igawa* | KC | sp | 28 | .884 | 495 | .293 | 431 | .555 | 443 | .571 | 128.0 | 6.8 | 6.19 | 6.39 |
| Jason Isringhausen | LAA | cl | 35 | .606 | 112 | .170 | 70 | .400 | 72 | .411 | 12.5 | 2.4 | 2.23 | 2.59 |
| Edwin Jackson | Hou | sp | 24 | .750 | 520 | .304 | 351 | .461 | 355 | .466 | 98.3 | 5.1 | 4.60 | 4.44 |
| Chuck James* | ChW | sp | 26 | .780 | 389 | .267 | 281 | .501 | 283 | .504 | 77.2 | 5.4 | 4.90 | 4.66 |
| Casey Janssen | LAA | mr | 26 | .684 | 220 | .282 | 117 | .403 | 120 | .414 | 30.8 | 4.1 | 3.79 | 3.69 |
| Bobby Jenks | Pit | cl | 27 | .429 | 254 | .236 | 83 | .241 | 84 | .243 | 14.9 | 1.4 | 1.30 | 1.14 |
| Jason Jennings | Cle | sp | 29 | .760 | 158 | .323 | 103 | .464 | 104 | .468 | 30.6 | 5.6 | 5.02 | 4.74 |
| Ubaldo Jimenez | NYY | sp | 24 | .836 | 257 | .288 | 206 | .524 | 212 | .539 | 60.7 | 6.3 | 5.78 | 5.58 |
| Josh Johnson | NYY | sp | 24 | 1.440 | 49 | .510 | 68 | .850 | 68 | .850 | 31.3 | 22.8 | 19.02 | 22.54 |
| Randy Johnson* | NYM | sp | 44 | .667 | 186 | .280 | 142 | .418 | 147 | .432 | 34.7 | 3.7 | 3.38 | 3.18 |
| Tyler Johnson* | Cle | mr | 27 | .531 | 123 | .228 | 53 | .306 | 56 | .324 | 12.3 | 2.5 | 2.31 | 1.82 |
| Todd Jones | ChC | cl | 40 | .688 | 334 | .281 | 173 | .411 | 176 | .418 | 43.1 | 3.8 | 3.48 | 3.49 |
| Jorge Julio | Phi | mr | 29 | .858 | 245 | .371 | 199 | .518 | 202 | .526 | 62.8 | 6.9 | 6.39 | 6.55 |
| Jair Jurrjens | Mil | sp | 22 | .636 | 104 | .154 | 60 | .435 | 62 | .449 | 12.4 | 3.2 | 2.85 | 1.98 |
| Jeff Karstens | Cin | mr | 25 | 1.250 | 57 | .421 | 60 | .769 | 60 | .769 | 22.8 | 14.7 | 13.85 | 13.32 |
| Scott Kazmir* | SF | sp | 24 | .684 | 557 | .334 | 367 | .408 | 376 | .418 | 96.5 | 4.1 | 3.73 | 3.71 |
| Kyle Kendrick | LAD | sp | 23 | .825 | 437 | .277 | 271 | .505 | 278 | .518 | 76.0 | 5.4 | 4.89 | 4.85 |
| Ian Kennedy | Phi | sp | 23 | .718 | 79 | .316 | 51 | .432 | 51 | .432 | 13.9 | 4.6 | 4.21 | 4.10 |
| Joe Kennedy* | Phi | mr | 29 | .882 | 496 | .306 | 339 | .520 | 352 | .540 | 109.7 | 7.1 | 6.50 | 6.56 |
| Logan Kensing | Mil | mr | 25 | .420 | 32 | .156 | 14 | .280 | 14 | .280 | 2.3 | 1.5 | 1.38 | 1.30 |
| Byung-Hyun Kim | Tam | sp | 29 | .757 | 150 | .253 | 115 | .494 | 117 | .502 | 30.4 | 5.1 | 4.70 | 4.36 |
| Ray King* | KC | mr | 34 | .904 | 252 | .290 | 213 | .573 | 217 | .583 | 62.6 | 7.1 | 6.45 | 6.57 |
| Steve Kline* | StL | mr | 35 | .860 | 216 | .352 | 129 | .500 | 130 | .504 | 42.8 | 7.0 | 6.54 | 6.56 |
| Mike Koplove | Col | mr | 31 | .517 | 12 | .167 | 5 | .333 | 5 | .333 | 1.1 | 2.6 | 2.18 | 1.51 |
| Hong-Chih Kuo* | Sea | sp | 26 | .523 | 30 | .200 | 12 | .333 | 12 | .333 | 1.9 | 1.8 | 1.59 | 1.46 |
| John Lackey | Hou | sp | 29 | .718 | 708 | .319 | 418 | .420 | 435 | .437 | 114.7 | 4.3 | 3.89 | 3.79 |
| Aaron Laffey* | ChW | sp | 23 | .664 | 218 | .284 | 107 | .388 | 110 | .399 | 22.8 | 2.9 | 2.64 | 3.04 |
| John Lannan* | Mil | sp | 23 | .932 | 133 | .353 | 85 | .535 | 86 | .541 | 30.1 | 8.6 | 7.79 | 8.85 |
| Brian Lawrence | Phi | sp | 32 | 1.114 | 107 | .439 | 98 | .667 | 98 | .667 | 41.1 | 14.2 | 13.33 | 13.71 |
| Cliff Lee* | Cle | sp | 29 | .951 | 306 | .343 | 256 | .584 | 261 | .596 | 88.7 | 8.8 | 7.78 | 7.35 |
| Jon Lester* | Sea | sp | 24 | .619 | 258 | .236 | 135 | .382 | 137 | .388 | 30.5 | 3.2 | 2.89 | 3.01 |
| Jensen Lewis | Min | mr | 24 | .595 | 107 | .280 | 60 | .359 | 62 | .371 | 14.0 | 3.1 | 2.88 | 2.77 |
| Brad Lidge | Atl | cl | 31 | .661 | 220 | .286 | 166 | .414 | 173 | .431 | 39.7 | 3.6 | 3.29 | 2.93 |
| Jon Lieber | Phi | sp | 38 | .881 | 264 | .383 | 188 | .521 | 191 | .529 | 60.6 | 6.9 | 6.38 | 6.00 |
| Ted Lilly* | Hou | sp | 32 | .689 | 640 | .270 | 394 | .431 | 398 | .435 | 95.9 | 3.8 | 3.45 | 3.13 |
| Tim Lincecum | Tor | sp | 24 | .751 | 417 | .312 | 321 | .476 | 325 | .482 | 87.6 | 5.1 | 4.61 | 4.24 |
| Matt Lindstrom | Bos | mr | 28 | .690 | 284 | .349 | 169 | .396 | 173 | .405 | 45.9 | 4.3 | 3.87 | 4.26 |
| Scott Linebrink | Mil | mr | 31 | .778 | 243 | .284 | 178 | .490 | 179 | .493 | 48.5 | 5.1 | 4.56 | 4.27 |
| Jesse Litsch | Cin | sp | 23 | .677 | 343 | .248 | 180 | .410 | 185 | .421 | 41.6 | 3.5 | 3.16 | 3.45 |
| Wes Littleton | Cin | mr | 25 | .699 | 201 | .209 | 115 | .442 | 119 | .458 | 26.4 | 3.7 | 3.32 | 3.34 |
| Bobby Livingston* | Col | sp | 25 | .918 | 608 | .372 | 403 | .541 | 407 | .546 | 139.5 | 7.8 | 6.98 | 6.52 |
| Radhames Liz | Bal | mr | 25 | .862 | 111 | .270 | 110 | .558 | 111 | .563 | 32.9 | 7.5 | 6.89 | 7.96 |
| Esteban Loaiza | Flo | sp | 36 | 1.344 | 93 | .333 | 130 | .850 | 131 | .856 | 50.5 | 15.9 | 14.62 | 15.72 |
| Kameron Loe | Bos | sp | 26 | .872 | 493 | .345 | 364 | .532 | 371 | .542 | 112.6 | 6.7 | 6.08 | 6.01 |
| Adam Loewen* | LAA | sp | 24 | .566 | 44 | .205 | 29 | .387 | 29 | .387 | 5.7 | 2.8 | 2.57 | 2.21 |
| Boone Logan* | Cle | mr | 23 | .767 | 55 | .291 | 32 | .444 | 33 | .458 | 9.2 | 5.4 | 4.96 | 5.82 |
| Kyle Lohse | Bal | sp | 29 | .763 | 618 | .312 | 391 | .463 | 395 | .468 | 112.2 | 5.3 | 4.84 | 4.68 |
| Braden Looper | Cle | sp | 33 | .686 | 685 | .261 | 382 | .420 | 391 | .430 | 92.1 | 3.7 | 3.36 | 3.34 |
| Aquilino Lopez | Sea | mr | 33 | 1.000 | 4 | .000 | 4 | .800 | 4 | .800 | 0.8 | 5.4 | 4.86 | 4.25 |
| Javier Lopez* | Col | mr | 30 | .752 | 198 | .253 | 131 | .468 | 135 | .482 | 34.6 | 4.9 | 4.41 | 4.70 |
| Rodrigo Lopez | StL | sp | 32 | .773 | 374 | .302 | 222 | .463 | 223 | .465 | 64.6 | 5.2 | 4.79 | 4.44 |
| Derek Lowe | ChW | sp | 35 | .708 | 631 | .281 | 397 | .441 | 399 | .443 | 101.7 | 4.3 | 3.91 | 4.01 |
| Mark Lowe | StL | mr | 25 | 1.367 | 12 | .500 | 15 | .833 | 15 | .833 | 7.0 | 21.1 | 18.95 | 16.51 |
| Noah Lowry* | Mil | sp | 27 | .889 | 495 | .305 | 402 | .552 | 408 | .560 | 118.2 | 6.7 | 6.12 | 6.64 |
| Ruddy Lugo | KC | mr | 28 | .801 | 314 | .290 | 240 | .513 | 243 | .519 | 66.7 | 5.8 | 5.21 | 4.88 |
| Brandon Lyon | Tam | mr | 28 | .622 | 326 | .261 | 162 | .376 | 165 | .383 | 38.5 | 3.3 | 2.97 | 2.57 |
| Mike MacDougal | Bal | mr | 31 | .894 | 81 | .370 | 71 | .559 | 72 | .567 | 24.1 | 8.2 | 7.61 | 6.34 |
| Greg Maddux | ChC | sp | 42 | .751 | 717 | .312 | 411 | .452 | 418 | .460 | 116.4 | 4.8 | 4.41 | 3.90 |
| Ryan Madson | NYM | mr | 27 | .580 | 271 | .266 | 128 | .342 | 130 | .348 | 28.0 | 2.7 | 2.42 | 2.44 |
| Ron Mahay* | Det | mr | 37 | .667 | 204 | .304 | 135 | .413 | 137 | .419 | 33.4 | 4.1 | 3.72 | 3.87 |
| Paul Maholm* | LAA | sp | 26 | .747 | 475 | .278 | 295 | .468 | 297 | .471 | 76.6 | 4.6 | 4.12 | 4.08 |
| John Maine | Oak | sp | 27 | .656 | 574 | .261 | 369 | .415 | 375 | .422 | 87.3 | 3.7 | 3.31 | 3.08 |
| Gary Majewski | Tex | mr | 28 | .934 | 59 | .356 | 43 | .589 | 43 | .589 | 14.1 | 7.7 | 7.12 | 6.12 |
| Shaun Marcum | Tam | sp | 26 | .693 | 566 | .246 | 367 | .449 | 368 | .450 | 82.3 | 3.6 | 3.31 | 3.25 |
| Carlos Marmol | Tam | mr | 25 | .487 | 172 | .256 | 100 | .309 | 102 | .315 | 18.6 | 2.1 | 1.84 | 1.70 |
| Jason Marquis | StL | sp | 29 | .777 | 624 | .300 | 386 | .458 | 399 | .474 | 111.8 | 5.2 | 4.72 | 4.73 |
| Jay Marshall* | Det | mr | 25 | .871 | 65 | .369 | 41 | .461 | 46 | .517 | 14.6 | 7.5 | 6.84 | 8.13 |
| Sean Marshall* | Flo | sp | 25 | .733 | 470 | .270 | 287 | .460 | 289 | .463 | 73.5 | 4.4 | 4.05 | 3.72 |
| Damaso Marte* | Ari | mr | 33 | .614 | 169 | .296 | 107 | .384 | 108 | .387 | 24.8 | 3.3 | 3.03 | 2.65 |
| Tom Martin* | Atl | mr | 38 | .947 | 367 | .332 | 260 | .566 | 264 | .575 | 93.0 | 8.9 | 7.95 | 8.04 |
| Carlos Martinez | Cin | mr | 26 | 1.561 | 13 | .231 | 22 | 1.048 | 22 | 1.048 | 9.0 | 20.3 | 18.26 | 17.48 |
| Pedro Martinez | Bos | sp | 36 | .683 | 90 | .367 | 60 | .403 | 62 | .416 | 16.6 | 4.3 | 3.95 | 3.67 |
| Nick Masset | Oak | mr | 26 | 1.132 | 27 | .370 | 27 | .692 | 27 | .692 | 10.9 | 14.7 | 14.69 | 15.67 |
| Tom Mastny | KC | mr | 27 | .771 | 357 | .328 | 267 | .481 | 270 | .486 | 73.9 | 5.2 | 4.69 | 4.44 |
| Julio Mateo | Cin | mr | 30 | .752 | 45 | .311 | 24 | .453 | 24 | .453 | 7.0 | 5.1 | 4.62 | 4.06 |
| Daisuke Matsuzaka | Cle | sp | 27 | .680 | 578 | .273 | 397 | .429 | 406 | .439 | 97.3 | 4.0 | 3.59 | 3.54 |
| Marcus McBeth | Bos | mr | 27 | 1.238 | 6 | .500 | 5 | .714 | 5 | .714 | 2.4 | 21.9 | 19.72 | 19.55 |
| Macay McBride* | Ari | mr | 25 | .529 | 62 | .258 | 30 | .306 | 32 | .327 | 6.2 | 2.3 | 2.11 | 2.43 |
| Brandon McCarthy | Ari | sp | 24 | .791 | 154 | .318 | 98 | .478 | 99 | .483 | 28.8 | 5.6 | 5.03 | 4.45 |
| Seth McClung | Mil | mr | 27 | .817 | 51 | .333 | 40 | .513 | 40 | .513 | 11.8 | 6.6 | 6.23 | 5.44 |
| Dustin McGowan | Sea | sp | 26 | .575 | 570 | .254 | 289 | .353 | 294 | .359 | 60.1 | 2.6 | 2.40 | 2.29 |
| Marty McLeary | NYM | mr | 33 | .250 | 3 | .000 | 1 | .250 | 1 | .250 | 0.1 | 0.6 | 0.53 | 0.94 |
| Mark McLemore* | NYY | mr | 27 | .969 | 49 | .388 | 52 | .612 | 52 | .612 | 17.9 | 9.7 | 8.87 | 8.33 |
| Gil Meche | Sea | sp | 29 | .643 | 726 | .263 | 381 | .393 | 384 | .396 | 84.6 | 3.1 | 2.83 | 2.84 |
| Brandon Medders | NYY | mr | 28 | .784 | 62 | .242 | 52 | .515 | 52 | .515 | 13.3 | 5.0 | 4.47 | 4.47 |
| Luis Mendoza | Mil | sp | 24 | .606 | 34 | .235 | 15 | .333 | 17 | .378 | 3.7 | 3.1 | 2.68 | 2.82 |
| Cla Meredith | Col | mr | 25 | .805 | 309 | .385 | 190 | .459 | 192 | .464 | 56.3 | 5.3 | 4.83 | 5.55 |
| Jose Mesa | NYM | mr | 42 | .752 | 111 | .261 | 71 | .467 | 72 | .474 | 18.9 | 4.9 | 4.45 | 4.43 |
| Randy Messenger | Phi | mr | 26 | .933 | 301 | .382 | 220 | .553 | 223 | .560 | 76.1 | 8.2 | 7.49 | 7.86 |
| Dan Meyer* | Oak | sp | 26 | 1.103 | 118 | .364 | 113 | .689 | 113 | .689 | 43.0 | 12.5 | 11.00 | 10.68 |
| Andrew Miller* | Mil | sp | 23 | 1.086 | 181 | .403 | 193 | .666 | 195 | .672 | 70.9 | 11.7 | 10.76 | 11.20 |
| Justin Miller | LAD | mr | 30 | .687 | 159 | .327 | 109 | .421 | 111 | .429 | 27.3 | 4.1 | 3.65 | 3.41 |
| Trever Miller* | Phi | mr | 35 | .944 | 127 | .378 | 104 | .565 | 106 | .576 | 36.5 | 8.8 | 7.85 | 7.83 |
| Kevin Millwood | StL | sp | 33 | .722 | 494 | .318 | 270 | .409 | 280 | .424 | 79.5 | 4.7 | 4.33 | 4.19 |
| Zach Miner | Pit | mr | 26 | .789 | 206 | .340 | 116 | .451 | 118 | .459 | 36.2 | 5.7 | 5.23 | 5.50 |
| Patrick Misch* | NYM | mr | 26 | .851 | 57 | .386 | 31 | .477 | 31 | .477 | 10.6 | 6.7 | 6.13 | 6.25 |
| Sergio Mitre | Cin | sp | 27 | .769 | 504 | .329 | 284 | .435 | 296 | .453 | 85.2 | 5.2 | 4.69 | 4.96 |
| Brian Moehler | Tor | mr | 36 | .750 | 408 | .311 | 252 | .457 | 254 | .461 | 64.0 | 4.4 | 3.96 | 4.05 |
| Franklin Morales* | Flo | sp | 22 | .659 | 200 | .255 | 111 | .410 | 112 | .413 | 27.2 | 3.7 | 3.37 | 3.17 |
| Juan Morillo | Bos | mr | 24 | .000 | 1 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Matt Morris | Oak | sp | 33 | .784 | 751 | .300 | 464 | .475 | 477 | .489 | 131.0 | 5.2 | 4.77 | 4.65 |
| Brandon Morrow | LAA | mr | 23 | .433 | 9 | .111 | 5 | .333 | 5 | .333 | 0.7 | 1.8 | 1.64 | 1.37 |
| Dustin Moseley | Was | mr | 26 | .650 | 343 | .251 | 168 | .398 | 169 | .400 | 38.3 | 3.3 | 2.95 | 2.57 |
| Guillermo Mota | Bal | mr | 34 | .708 | 227 | .313 | 137 | .425 | 140 | .435 | 39.0 | 4.7 | 4.23 | 3.64 |
| Jamie Moyer* | Phi | sp | 45 | .892 | 754 | .328 | 566 | .557 | 573 | .563 | 179.6 | 7.2 | 6.55 | 5.94 |
| Peter Moylan | Cin | mr | 29 | .683 | 326 | .267 | 189 | .415 | 195 | .429 | 47.4 | 3.8 | 3.43 | 3.01 |
| Arnie Munoz* | Phi | mr | 26 | 1.178 | 45 | .400 | 50 | .704 | 50 | .704 | 18.8 | 13.7 | 12.33 | 14.55 |
| A.J. Murray* | Det | mr | 26 | .853 | 85 | .282 | 69 | .543 | 70 | .551 | 19.9 | 6.4 | 5.55 | 5.34 |
| Mike Mussina | SD | sp | 39 | .927 | 534 | .371 | 389 | .560 | 391 | .563 | 130.0 | 7.8 | 7.01 | 6.68 |
| Brett Myers | LAA | cl | 27 | .633 | 198 | .278 | 141 | .403 | 144 | .411 | 33.5 | 3.7 | 3.36 | 3.29 |
| Mike Myers* | Tex | mr | 39 | .675 | 247 | .223 | 129 | .416 | 134 | .432 | 32.4 | 3.9 | 3.61 | 3.32 |
| Joe Nathan | ChW | cl | 33 | .492 | 171 | .275 | 79 | .297 | 79 | .297 | 14.2 | 1.8 | 1.61 | 1.37 |
| Pat Neshek | Ari | mr | 27 | .532 | 220 | .214 | 116 | .333 | 121 | .348 | 22.9 | 2.3 | 2.11 | 1.67 |
| Dustin Nippert | ChW | mr | 27 | .860 | 94 | .340 | 77 | .542 | 77 | .542 | 22.6 | 6.3 | 5.67 | 5.75 |
| Ricky Nolasco | Cin | sp | 25 | .886 | 96 | .365 | 65 | .528 | 66 | .537 | 22.6 | 7.8 | 6.94 | 6.99 |
| Leo Nunez | NYM | mr | 24 | .686 | 127 | .213 | 86 | .462 | 86 | .462 | 18.6 | 3.5 | 3.16 | 2.73 |
| Eric O'Flaherty* | NYM | mr | 23 | .750 | 269 | .335 | 162 | .423 | 173 | .452 | 49.0 | 5.3 | 4.84 | 4.92 |
| Tomo Ohka | Mil | sp | 32 | .645 | 241 | .257 | 118 | .381 | 119 | .384 | 27.8 | 3.3 | 3.08 | 3.25 |
| Ross Ohlendorf | NYM | mr | 25 | .700 | 9 | .333 | 6 | .400 | 6 | .400 | 1.8 | 4.8 | 4.33 | 4.87 |
| Will Ohman* | StL | mr | 30 | .757 | 133 | .316 | 84 | .454 | 85 | .459 | 23.1 | 4.8 | 4.29 | 3.86 |
| Hideki Okajima* | SD | mr | 32 | .423 | 237 | .207 | 82 | .252 | 82 | .252 | 14.2 | 1.5 | 1.36 | 1.29 |
| Darren Oliver* | Cle | mr | 37 | .782 | 140 | .350 | 101 | .468 | 104 | .481 | 32.0 | 6.3 | 5.68 | 5.58 |
| Scott Olsen* | Hou | sp | 24 | .860 | 59 | .373 | 44 | .518 | 44 | .518 | 13.4 | 6.6 | 6.24 | 6.62 |
| Garrett Olson* | Was | sp | 24 | 1.070 | 45 | .356 | 41 | .612 | 44 | .657 | 15.5 | 11.3 | 10.19 | 11.73 |
| Ramon Ortiz | Pit | mr | 35 | .808 | 459 | .281 | 287 | .491 | 297 | .508 | 83.4 | 5.5 | 4.92 | 4.58 |
| Russ Ortiz | StL | sp | 34 | 1.319 | 24 | .375 | 27 | .871 | 27 | .871 | 11.5 | 17.3 | 15.58 | 14.72 |
| Chad Orvella | Col | mr | 27 | 1.700 | 7 | .571 | 10 | .909 | 10 | .909 | 5.8 | 38.8 | 27.96 | 30.88 |
| Franquelis Osoria | Tex | mr | 26 | .725 | 49 | .265 | 29 | .439 | 30 | .455 | 7.9 | 4.6 | 4.09 | 4.01 |
| Roy Oswalt | Ari | sp | 30 | .789 | 630 | .319 | 409 | .466 | 425 | .485 | 119.5 | 5.4 | 4.77 | 4.41 |
| Akinori Otsuka | Tex | mr | 36 | .609 | 125 | .264 | 62 | .369 | 62 | .369 | 14.0 | 3.0 | 2.77 | 2.72 |
| Henry Owens | NYY | mr | 29 | .701 | 63 | .222 | 43 | .462 | 43 | .462 | 10.3 | 4.2 | 3.84 | 3.22 |
| Micah Owings | LAA | sp | 25 | .671 | 501 | .257 | 291 | .410 | 302 | .425 | 71.0 | 3.7 | 3.39 | 3.33 |
| Vicente Padilla | Flo | sp | 30 | .759 | 478 | .333 | 292 | .446 | 297 | .454 | 84.4 | 5.2 | 4.75 | 4.84 |
| Jonathan Papelbon | LAD | cl | 27 | .485 | 156 | .205 | 81 | .290 | 88 | .315 | 16.0 | 2.0 | 1.78 | 1.51 |
| Manny Parra* | Hou | mr | 25 | .882 | 54 | .370 | 39 | .520 | 41 | .547 | 12.4 | 7.1 | 6.83 | 6.53 |
| John Parrish* | Min | mr | 30 | .919 | 89 | .427 | 77 | .554 | 77 | .554 | 26.1 | 9.0 | 8.13 | 9.06 |
| Troy Patton* | Cle | sp | 22 | 1.362 | 43 | .395 | 64 | .877 | 65 | .890 | 26.8 | 19.0 | 18.08 | 17.96 |
| Felipe Paulino | Mil | sp | 24 | 1.129 | 48 | .292 | 45 | .738 | 45 | .738 | 14.8 | 10.0 | 9.24 | 8.75 |
| Carl Pavano | NYY | sp | 32 | .636 | 72 | .278 | 33 | .375 | 33 | .375 | 8.1 | 3.4 | 3.14 | 2.62 |
| Jake Peavy | SD | sp | 27 | .624 | 623 | .294 | 369 | .380 | 376 | .387 | 85.7 | 3.2 | 2.89 | 2.47 |
| Mike Pelfrey | NYM | sp | 24 | .905 | 250 | .364 | 174 | .510 | 181 | .531 | 60.3 | 7.8 | 6.95 | 7.38 |
| Tony Pena | SF | mr | 26 | .622 | 288 | .250 | 165 | .380 | 170 | .392 | 38.1 | 3.2 | 2.94 | 2.90 |
| Brad Penny | Tam | sp | 30 | .773 | 564 | .312 | 372 | .469 | 379 | .477 | 105.4 | 5.3 | 4.80 | 4.90 |
| Joel Peralta | Tam | mr | 32 | .827 | 394 | .312 | 270 | .516 | 271 | .518 | 76.5 | 5.6 | 5.12 | 4.92 |
| Troy Percival | SD | mr | 38 | .561 | 189 | .249 | 95 | .344 | 96 | .348 | 20.8 | 2.7 | 2.44 | 2.01 |
| Odalis Perez* | Cin | sp | 31 | .781 | 578 | .303 | 349 | .468 | 355 | .476 | 99.7 | 5.3 | 4.78 | 4.79 |
| Oliver Perez* | Min | sp | 26 | .731 | 555 | .292 | 385 | .453 | 392 | .461 | 104.7 | 4.9 | 4.51 | 4.43 |
| Rafael Perez* | NYY | mr | 26 | .437 | 148 | .196 | 62 | .270 | 64 | .278 | 9.9 | 1.4 | 1.29 | 1.14 |
| Glen Perkins* | Pit | mr | 25 | .572 | 72 | .250 | 37 | .346 | 39 | .364 | 8.3 | 3.1 | 2.77 | 2.96 |
| Yusmeiro Petit | Tam | sp | 23 | .815 | 193 | .311 | 146 | .523 | 146 | .523 | 39.6 | 5.6 | 4.99 | 4.71 |
| Billy Petrick | Min | mr | 24 | .250 | 3 | .000 | 1 | .250 | 1 | .250 | 0.1 | 0.6 | 0.53 | 0.94 |
| Andy Pettitte* | Tex | sp | 36 | .806 | 766 | .360 | 482 | .474 | 485 | .477 | 147.7 | 5.9 | 5.33 | 5.58 |
| Joel Pineiro | Bal | mr | 29 | .864 | 296 | .297 | 221 | .544 | 222 | .547 | 66.0 | 6.5 | 5.90 | 5.65 |
| Renyel Pinto* | Bos | mr | 25 | .837 | 150 | .313 | 161 | .530 | 167 | .549 | 45.1 | 6.6 | 5.92 | 6.91 |
| Sidney Ponson | Flo | sp | 31 | 1.647 | 18 | .556 | 31 | 1.107 | 31 | 1.107 | 16.2 | 33.7 | 30.30 | 28.33 |
| Scott Proctor | LAA | mr | 31 | .805 | 119 | .261 | 94 | .492 | 100 | .524 | 27.6 | 5.8 | 5.08 | 4.97 |
| J.J. Putz | SD | cl | 31 | .353 | 187 | .155 | 63 | .225 | 63 | .225 | 7.0 | 0.8 | 0.71 | 0.77 |
| Chad Qualls | LAD | mr | 29 | .720 | 217 | .359 | 131 | .397 | 138 | .418 | 39.7 | 4.7 | 4.29 | 4.50 |
| Edwar Ramirez | NYY | mr | 27 | .867 | 19 | .579 | 22 | .478 | 24 | .522 | 8.2 | 8.5 | 7.66 | 8.36 |
| Elizardo Ramirez | Phi | sp | 25 | .801 | 76 | .276 | 54 | .495 | 54 | .495 | 16.4 | 6.1 | 5.61 | 5.33 |
| Horacio Ramirez* | KC | sp | 28 | .895 | 596 | .329 | 404 | .539 | 407 | .543 | 127.2 | 7.1 | 6.42 | 6.97 |
| Ramon Ramirez | Col | mr | 26 | .757 | 96 | .302 | 54 | .450 | 56 | .467 | 14.3 | 4.4 | 3.89 | 3.61 |
| Darrell Rasner | Tex | sp | 27 | 1.002 | 144 | .306 | 118 | .611 | 124 | .642 | 41.8 | 9.3 | 8.45 | 7.72 |
| Jon Rauch | ChW | mr | 29 | .591 | 271 | .288 | 127 | .346 | 128 | .349 | 30.9 | 3.1 | 2.78 | 2.47 |
| Chris Ray | Flo | cl | 26 | .699 | 138 | .275 | 97 | .435 | 100 | .448 | 24.7 | 4.1 | 3.70 | 3.20 |
| Tim Redding | SF | sp | 30 | .745 | 355 | .285 | 214 | .436 | 222 | .452 | 61.3 | 5.0 | 4.49 | 4.57 |
| Mark Redman* | ChC | sp | 34 | 1.227 | 21 | .476 | 20 | .741 | 20 | .741 | 8.4 | 16.3 | 15.77 | 16.51 |
| Al Reyes | Flo | cl | 38 | .685 | 140 | .243 | 115 | .455 | 115 | .455 | 27.1 | 3.9 | 3.46 | 2.94 |
| Anthony Reyes | Hou | sp | 26 | .789 | 405 | .272 | 276 | .491 | 284 | .505 | 78.1 | 5.4 | 4.89 | 4.66 |
| Dennys Reyes* | Bal | mr | 31 | .969 | 114 | .395 | 107 | .582 | 110 | .598 | 33.9 | 8.5 | 7.63 | 9.51 |
| Jo-Jo Reyes* | Ari | sp | 23 | .778 | 167 | .251 | 124 | .498 | 125 | .502 | 33.4 | 5.4 | 4.89 | 5.37 |
| John Rheinecker* | StL | mr | 29 | .700 | 16 | .313 | 11 | .440 | 11 | .440 | 2.9 | 5.3 | 5.46 | 6.41 |
| Juan Rincon | Tex | mr | 29 | .810 | 260 | .285 | 202 | .511 | 205 | .519 | 54.6 | 5.5 | 4.97 | 5.20 |
| David Riske | Bal | mr | 31 | .635 | 233 | .253 | 134 | .405 | 134 | .405 | 29.1 | 3.2 | 2.88 | 2.71 |
| Mariano Rivera | Flo | cl | 38 | .753 | 218 | .330 | 141 | .450 | 148 | .473 | 37.5 | 4.5 | 4.08 | 3.86 |
| Saul Rivera | Cin | mr | 30 | .793 | 345 | .330 | 219 | .474 | 220 | .476 | 63.3 | 5.5 | 4.96 | 4.81 |
| Nate Robertson* | Was | sp | 30 | .727 | 636 | .280 | 365 | .432 | 372 | .440 | 96.4 | 4.4 | 4.05 | 4.03 |
| Fernando Rodney | KC | mr | 31 | .799 | 172 | .314 | 141 | .504 | 144 | .514 | 39.4 | 5.6 | 5.01 | 5.08 |
| Francisco Rodriguez | Col | cl | 26 | .605 | 149 | .309 | 112 | .378 | 116 | .392 | 25.2 | 3.1 | 2.84 | 2.64 |
| Wandy Rodriguez* | Min | sp | 29 | .771 | 559 | .322 | 361 | .468 | 366 | .475 | 102.3 | 5.3 | 4.77 | 4.52 |
| Kenny Rogers* | NYM | sp | 43 | .789 | 279 | .290 | 172 | .473 | 175 | .481 | 49.4 | 5.4 | 4.84 | 4.77 |
| J.C. Romero* | Was | mr | 32 | .594 | 132 | .220 | 77 | .379 | 79 | .389 | 13.9 | 2.6 | 2.31 | 2.72 |
| Ryan Rowland-Smith* | SF | mr | 25 | .890 | 76 | .382 | 71 | .555 | 71 | .555 | 22.0 | 7.1 | 6.36 | 6.65 |
| Jae Kuk Ryu | Sea | mr | 25 | 1.105 | 11 | .545 | 14 | .667 | 14 | .667 | 5.0 | 13.5 | 12.17 | 14.96 |
| Kirk Saarloos | Phi | mr | 29 | 1.123 | 160 | .331 | 172 | .702 | 176 | .718 | 62.3 | 11.5 | 10.30 | 10.32 |
| C.C. Sabathia* | ChW | sp | 27 | .758 | 688 | .333 | 426 | .460 | 431 | .465 | 117.1 | 4.8 | 4.30 | 3.97 |
| Takashi Saito | SD | cl | 38 | .348 | 200 | .190 | 74 | .214 | 77 | .223 | 9.5 | 0.9 | 0.78 | 0.72 |
| Juan Salas | NYY | mr | 29 | .736 | 120 | .242 | 85 | .452 | 90 | .479 | 23.3 | 4.9 | 4.50 | 4.64 |
| Brad Salmon | Bal | mr | 28 | .871 | 89 | .382 | 74 | .532 | 74 | .532 | 23.1 | 6.8 | 6.11 | 6.37 |
| Chris Sampson | Min | sp | 30 | .829 | 429 | .289 | 278 | .507 | 284 | .518 | 81.7 | 5.9 | 5.34 | 5.50 |
| Anibal Sanchez | Bos | sp | 24 | .952 | 23 | .391 | 16 | .552 | 16 | .552 | 6.2 | 9.9 | 7.96 | 8.10 |
| Jonathan Sanchez* | KC | mr | 25 | .502 | 25 | .280 | 13 | .310 | 13 | .310 | 2.7 | 2.4 | 2.15 | 2.17 |
| Romulo Sanchez | Col | mr | 24 | .817 | 24 | .292 | 23 | .535 | 23 | .535 | 6.4 | 6.2 | 5.76 | 6.46 |
| Ervin Santana | Bos | sp | 25 | .888 | 447 | .329 | 386 | .561 | 393 | .571 | 121.1 | 7.2 | 6.59 | 6.31 |
| Johan Santana* | Mil | sp | 29 | .738 | 506 | .291 | 375 | .471 | 381 | .479 | 94.0 | 4.3 | 3.94 | 3.67 |
| Victor Santos | NYY | mr | 31 | 1.088 | 134 | .396 | 140 | .683 | 141 | .688 | 49.1 | 10.5 | 9.24 | 9.16 |
| Dennis Sarfate | Sea | mr | 27 | .692 | 8 | .500 | 5 | .385 | 5 | .385 | 1.5 | 4.6 | 4.15 | 3.56 |
| Joe Saunders* | SF | sp | 27 | .721 | 438 | .331 | 250 | .425 | 253 | .430 | 71.2 | 4.7 | 4.35 | 3.98 |
| Curt Schilling | Mil | sp | 41 | .732 | 561 | .308 | 317 | .439 | 319 | .442 | 88.5 | 4.6 | 4.20 | 3.71 |
| Jason Schmidt | Phi | sp | 35 | .965 | 127 | .346 | 112 | .599 | 114 | .610 | 36.6 | 8.2 | 7.53 | 7.53 |
| Scott Schoeneweis* | NYM | mr | 34 | .882 | 233 | .296 | 192 | .555 | 195 | .564 | 55.0 | 6.4 | 5.81 | 6.18 |
| Chris Schroder | Tor | mr | 29 | .661 | 221 | .258 | 134 | .409 | 138 | .421 | 33.2 | 3.8 | 3.46 | 3.00 |
| Rudy Seanez | Tor | mr | 39 | .882 | 169 | .379 | 139 | .527 | 144 | .545 | 46.0 | 7.6 | 6.82 | 7.39 |
| Bobby Seay* | NYY | mr | 30 | .511 | 84 | .238 | 35 | .297 | 36 | .305 | 6.4 | 1.9 | 1.72 | 1.77 |
| Chris Seddon* | Cin | sp | 24 | 1.156 | 45 | .422 | 46 | .676 | 47 | .691 | 18.3 | 13.7 | 12.02 | 12.51 |
| Zack Segovia | Tor | sp | 25 | 1.100 | 7 | .571 | 5 | .500 | 6 | .600 | 2.7 | 18.3 | 16.48 | 22.07 |
| Aaron Sele | NYY | mr | 38 | .985 | 185 | .405 | 144 | .581 | 148 | .597 | 50.9 | 9.2 | 8.42 | 8.00 |
| Jae Seo | LAD | sp | 31 | 1.079 | 47 | .340 | 44 | .667 | 45 | .682 | 14.7 | 9.4 | 8.69 | 10.50 |
| Tom Shearn | Flo | sp | 30 | .779 | 175 | .263 | 117 | .492 | 118 | .496 | 31.3 | 5.1 | 4.67 | 4.93 |
| Ben Sheets | Tex | sp | 29 | .708 | 532 | .263 | 334 | .442 | 341 | .451 | 86.2 | 4.3 | 3.88 | 3.63 |
| George Sherrill* | Min | mr | 31 | .595 | 204 | .260 | 129 | .372 | 132 | .380 | 29.1 | 3.1 | 2.84 | 2.44 |
| James Shields | LAD | sp | 26 | .674 | 646 | .272 | 379 | .404 | 398 | .424 | 93.8 | 3.6 | 3.32 | 3.01 |
| Scot Shields | SF | mr | 32 | .580 | 218 | .252 | 123 | .351 | 127 | .363 | 26.3 | 2.7 | 2.42 | 2.37 |
| Brian Shouse* | Sea | mr | 39 | .556 | 138 | .312 | 57 | .300 | 59 | .311 | 13.1 | 2.4 | 2.19 | 2.13 |
| Carlos Silva | Det | sp | 29 | .761 | 719 | .289 | 413 | .462 | 417 | .467 | 113.0 | 4.8 | 4.40 | 4.43 |
| Jason Simontacchi | NYM | sp | 34 | .921 | 267 | .356 | 214 | .568 | 216 | .573 | 68.9 | 7.4 | 6.81 | 6.19 |
| Andrew Sisco* | LAD | mr | 25 | .995 | 56 | .321 | 50 | .617 | 50 | .617 | 17.6 | 9.9 | 8.72 | 8.41 |
| Doug Slaten* | ChW | mr | 28 | .821 | 135 | .341 | 88 | .489 | 89 | .494 | 27.0 | 6.2 | 5.51 | 5.53 |
| Kevin Slowey | NYY | sp | 24 | .888 | 230 | .322 | 187 | .574 | 188 | .577 | 56.1 | 6.7 | 6.08 | 5.54 |
| Joe Smith | ChW | mr | 24 | .930 | 77 | .390 | 66 | .559 | 68 | .576 | 21.6 | 7.9 | 7.29 | 8.18 |
| John Smoltz | ChW | sp | 41 | .702 | 627 | .330 | 388 | .424 | 391 | .427 | 104.9 | 4.4 | 3.96 | 3.71 |
| Ian Snell | Was | sp | 26 | .631 | 645 | .265 | 352 | .381 | 364 | .394 | 82.6 | 3.2 | 2.94 | 2.70 |
| Kyle Snyder | Bos | mr | 30 | .604 | 232 | .203 | 128 | .375 | 135 | .396 | 30.6 | 3.4 | 3.09 | 3.02 |
| Andy Sonnanstine | Bos | sp | 25 | .746 | 484 | .308 | 283 | .448 | 289 | .457 | 75.2 | 4.5 | 4.11 | 4.06 |
| Joakim Soria | StL | cl | 24 | .502 | 177 | .271 | 78 | .285 | 81 | .296 | 17.3 | 2.2 | 2.05 | 1.62 |
| Rafael Soriano | Atl | mr | 28 | .602 | 298 | .228 | 167 | .380 | 170 | .387 | 34.8 | 2.7 | 2.51 | 2.25 |
| Jorge Sosa | Tor | mr | 31 | .844 | 466 | .309 | 350 | .530 | 354 | .536 | 102.7 | 6.3 | 5.70 | 5.55 |
| Jeremy Sowers* | Pit | sp | 25 | .789 | 238 | .273 | 143 | .470 | 148 | .487 | 43.2 | 5.6 | 5.05 | 4.26 |
| Justin Speier | Phi | mr | 34 | .735 | 150 | .253 | 113 | .440 | 125 | .486 | 29.6 | 4.3 | 3.83 | 3.57 |
| Ryan Speier | Min | mr | 28 | .595 | 90 | .256 | 42 | .356 | 44 | .373 | 9.8 | 3.0 | 2.63 | 1.94 |
| Russ Springer | Hou | mr | 39 | .652 | 276 | .283 | 169 | .397 | 175 | .411 | 39.2 | 3.4 | 3.03 | 2.73 |
| Chris Spurling | NYY | mr | 31 | .753 | 209 | .321 | 116 | .434 | 120 | .449 | 32.8 | 4.8 | 4.40 | 4.69 |
| Jason Stanford* | Was | mr | 31 | .776 | 33 | .394 | 17 | .405 | 18 | .429 | 5.8 | 5.8 | 5.24 | 5.61 |
| Mike Stanton* | Tor | mr | 41 | .884 | 224 | .371 | 162 | .528 | 164 | .534 | 53.6 | 7.5 | 6.82 | 6.98 |
| Tim Stauffer | KC | sp | 26 | 1.473 | 21 | .476 | 28 | .824 | 30 | .882 | 14.2 | 25.5 | 24.58 | 28.67 |
| Mitch Stetter* | Bos | mr | 27 | 1.750 | 1 | 1.000 | 3 | .750 | 4 | 1.000 | 1.9 | 51.0 | 45.93 | 44.74 |
| Huston Street | Det | cl | 24 | .505 | 166 | .247 | 89 | .314 | 90 | .318 | 16.4 | 2.0 | 1.80 | 1.49 |
| Jeff Suppan | Tex | sp | 33 | .881 | 787 | .358 | 527 | .523 | 540 | .536 | 172.8 | 7.2 | 6.39 | 6.20 |
| Jon Switzer* | Was | mr | 28 | .489 | 14 | .071 | 6 | .353 | 6 | .353 | 0.9 | 1.8 | 1.61 | 1.34 |
| Brian Tallet* | SF | mr | 30 | .538 | 215 | .265 | 91 | .307 | 94 | .318 | 20.6 | 2.5 | 2.28 | 2.18 |
| Taylor Tankersley* | Bal | mr | 25 | .795 | 157 | .395 | 116 | .450 | 122 | .473 | 36.2 | 6.1 | 5.49 | 6.67 |
| Jack Taschner* | Cin | mr | 30 | .804 | 192 | .292 | 169 | .518 | 172 | .528 | 46.2 | 5.9 | 5.28 | 5.29 |
| Jordan Tata | Cle | sp | 26 | .975 | 14 | .286 | 16 | .667 | 16 | .667 | 4.9 | 8.8 | 7.43 | 5.94 |
| Ty Taubenheim | Min | sp | 25 | 1.533 | 4 | .750 | 8 | .800 | 9 | .900 | 4.2 | 38.1 | 34.25 | 34.66 |
| Julian Tavarez | Phi | sp | 35 | .830 | 579 | .318 | 392 | .503 | 401 | .514 | 114.1 | 5.8 | 5.16 | 5.24 |
| Robinson Tejeda | Tex | sp | 26 | .882 | 277 | .300 | 248 | .555 | 255 | .570 | 77.8 | 7.4 | 6.65 | 6.59 |
| Joe Thatcher* | LAD | mr | 26 | .559 | 59 | .203 | 32 | .352 | 34 | .374 | 6.7 | 2.6 | 2.38 | 1.79 |
| Brad Thompson | LAD | mr | 26 | .895 | 109 | .294 | 77 | .538 | 79 | .552 | 23.8 | 6.8 | 6.22 | 7.01 |
| John Thomson | Col | sp | 34 | .859 | 74 | .365 | 48 | .522 | 48 | .522 | 14.9 | 6.5 | 6.03 | 4.85 |
| Matt Thornton* | Mil | mr | 31 | .724 | 268 | .321 | 168 | .432 | 172 | .442 | 44.8 | 4.4 | 3.99 | 3.43 |
| Erick Threets* | SF | mr | 26 | .788 | 5 | .400 | 7 | .538 | 7 | .538 | 1.8 | 8.0 | 6.17 | 9.90 |
| Mike Timlin | Mil | mr | 42 | .641 | 192 | .208 | 100 | .392 | 105 | .412 | 22.7 | 3.1 | 2.83 | 2.62 |
| Brett Tomko | Was | mr | 35 | .807 | 288 | .340 | 209 | .491 | 212 | .498 | 60.6 | 5.8 | 5.20 | 5.42 |
| Salomon Torres | Bos | mr | 36 | .690 | 193 | .264 | 121 | .419 | 125 | .433 | 29.9 | 3.9 | 3.67 | 3.77 |
| Josh Towers | Oak | sp | 31 | .761 | 391 | .302 | 253 | .475 | 256 | .480 | 66.3 | 4.7 | 4.19 | 4.02 |
| Billy Traber* | Tor | mr | 28 | 1.066 | 93 | .419 | 87 | .635 | 88 | .642 | 32.1 | 11.4 | 10.25 | 11.54 |
| Steve Trachsel | Phi | sp | 37 | .872 | 654 | .309 | 447 | .532 | 451 | .537 | 143.1 | 7.1 | 6.51 | 6.47 |
| Chin-hui Tsao | Pit | mr | 27 | .574 | 117 | .265 | 53 | .335 | 54 | .342 | 12.4 | 2.9 | 2.59 | 2.28 |
| Derrick Turnbow | ChC | mr | 30 | .602 | 173 | .260 | 137 | .399 | 138 | .402 | 28.2 | 3.2 | 2.86 | 3.28 |
| Jose Valverde | LAD | cl | 28 | .662 | 218 | .280 | 150 | .412 | 154 | .423 | 36.1 | 3.6 | 3.24 | 3.11 |
| John Van Benschoten | Pit | sp | 28 | .684 | 75 | .240 | 49 | .412 | 52 | .437 | 12.4 | 4.3 | 3.92 | 4.64 |
| Rick VandenHurk | ChW | sp | 23 | .951 | 11 | .364 | 11 | .611 | 11 | .611 | 3.9 | 9.6 | 9.49 | 9.05 |
| Claudio Vargas | Oak | sp | 30 | .832 | 496 | .325 | 362 | .509 | 369 | .519 | 109.9 | 6.4 | 5.82 | 5.86 |
| Javier Vazquez | Cle | sp | 31 | .663 | 582 | .254 | 385 | .421 | 393 | .430 | 90.3 | 3.6 | 3.23 | 2.93 |
| Jose Veras | Det | mr | 27 | .657 | 56 | .268 | 36 | .419 | 36 | .419 | 8.4 | 4.1 | 3.76 | 4.59 |
| Justin Verlander | Tor | sp | 25 | .714 | 677 | .256 | 453 | .443 | 473 | .462 | 120.4 | 4.5 | 4.14 | 3.99 |
| Carlos Villanueva | LAD | mr | 24 | .751 | 239 | .251 | 172 | .475 | 174 | .481 | 44.4 | 4.8 | 4.26 | 4.19 |
| Oscar Villarreal | Oak | mr | 26 | .685 | 402 | .286 | 232 | .417 | 236 | .424 | 62.3 | 4.4 | 3.96 | 3.57 |
| Ron Villone* | StL | mr | 38 | .497 | 124 | .210 | 49 | .290 | 52 | .308 | 9.7 | 1.9 | 1.79 | 1.54 |
| Luis Vizcaino | Hou | mr | 33 | .675 | 300 | .243 | 186 | .434 | 188 | .438 | 45.4 | 4.0 | 3.61 | 3.05 |
| Edinson Volquez | Ari | sp | 24 | .819 | 138 | .268 | 110 | .505 | 116 | .532 | 29.0 | 5.1 | 4.69 | 5.06 |
| Billy Wagner* | ChW | cl | 36 | .599 | 160 | .294 | 110 | .370 | 113 | .380 | 24.4 | 3.0 | 2.70 | 2.55 |
| Adam Wainwright | ChC | sp | 26 | .652 | 645 | .281 | 335 | .379 | 351 | .397 | 83.5 | 3.5 | 3.21 | 3.12 |
| Tim Wakefield | Det | sp | 41 | .775 | 580 | .288 | 391 | .485 | 395 | .490 | 108.0 | 5.2 | 4.69 | 4.57 |
| Jamie Walker* | Atl | mr | 36 | .597 | 239 | .264 | 116 | .354 | 119 | .363 | 27.9 | 3.1 | 2.78 | 2.45 |
| Tyler Walker | Pit | mr | 32 | .802 | 29 | .379 | 15 | .429 | 15 | .429 | 5.3 | 6.3 | 5.65 | 5.29 |
| Chien-Ming Wang | SD | sp | 28 | .579 | 709 | .244 | 296 | .338 | 307 | .350 | 64.7 | 2.6 | 2.37 | 2.14 |
| Jarrod Washburn* | NYM | sp | 33 | .782 | 660 | .300 | 415 | .476 | 420 | .482 | 116.3 | 5.3 | 4.73 | 4.70 |
| Ehren Wassermann | Col | mr | 27 | .844 | 142 | .338 | 94 | .487 | 101 | .523 | 30.2 | 6.4 | 5.83 | 5.15 |
| David Weathers | Cle | cl | 38 | .608 | 213 | .207 | 112 | .371 | 118 | .391 | 23.2 | 2.8 | 2.53 | 2.83 |
| Jeff Weaver | Col | sp | 31 | .871 | 672 | .317 | 459 | .531 | 469 | .543 | 141.8 | 6.5 | 5.86 | 5.51 |
| Jered Weaver | Cin | sp | 25 | .762 | 615 | .302 | 406 | .474 | 408 | .476 | 112.1 | 5.0 | 4.50 | 4.29 |
| Brandon Webb | Sea | sp | 29 | .610 | 660 | .285 | 344 | .364 | 350 | .371 | 82.1 | 3.2 | 2.93 | 2.76 |
| Todd Wellemeyer | Det | mr | 29 | .772 | 292 | .291 | 217 | .487 | 219 | .491 | 59.6 | 5.3 | 4.91 | 5.07 |
| David Wells* | NYY | sp | 45 | .881 | 605 | .370 | 416 | .525 | 421 | .531 | 134.4 | 7.1 | 6.36 | 6.36 |
| Kip Wells | Tex | sp | 31 | .850 | 548 | .336 | 414 | .519 | 425 | .533 | 131.6 | 7.0 | 6.42 | 6.25 |
| Jake Westbrook | Was | sp | 30 | .713 | 574 | .277 | 325 | .435 | 328 | .439 | 85.5 | 4.4 | 3.91 | 3.63 |
| Dan Wheeler | Cle | mr | 30 | .930 | 158 | .342 | 152 | .594 | 155 | .605 | 47.4 | 7.4 | 6.94 | 7.01 |
| Bob Wickman | Tex | cl | 39 | .893 | 93 | .355 | 72 | .522 | 74 | .536 | 23.0 | 7.0 | 6.36 | 6.49 |
| Todd Williams | Mil | mr | 37 | .885 | 96 | .396 | 64 | .492 | 67 | .515 | 22.0 | 7.3 | 6.37 | 6.99 |
| Woody Williams | KC | sp | 41 | .759 | 718 | .266 | 449 | .464 | 466 | .482 | 124.5 | 5.0 | 4.49 | 4.25 |
| Scott Williamson | Tam | mr | 32 | .802 | 16 | .250 | 15 | .517 | 15 | .517 | 4.0 | 5.7 | 5.12 | 5.58 |
| Dontrelle Willis* | SF | sp | 26 | .863 | 629 | .328 | 490 | .528 | 499 | .538 | 149.3 | 6.7 | 6.09 | 6.20 |
| Brian Wilson | Was | cl | 26 | .408 | 53 | .208 | 17 | .233 | 18 | .247 | 2.6 | 1.1 | 1.02 | 0.99 |
| C.J. Wilson* | Pit | mr | 27 | .687 | 272 | .287 | 163 | .414 | 166 | .421 | 38.2 | 3.6 | 3.29 | 3.65 |
| Matt Wise | SF | mr | 32 | .737 | 178 | .343 | 107 | .425 | 108 | .429 | 29.6 | 4.6 | 4.20 | 4.35 |
| Randy Wolf* | Bos | sp | 31 | .832 | 300 | .383 | 222 | .503 | 224 | .508 | 68.0 | 6.2 | 5.60 | 5.64 |
| Brian Wolfe | StL | mr | 27 | .555 | 197 | .228 | 87 | .340 | 88 | .344 | 18.2 | 2.6 | 2.34 | 1.99 |
| Kerry Wood | Mil | mr | 31 | .479 | 59 | .237 | 29 | .305 | 29 | .305 | 4.8 | 1.8 | 1.65 | 1.86 |
| Jamey Wright | ChC | mr | 33 | .698 | 232 | .241 | 126 | .413 | 134 | .439 | 31.3 | 3.8 | 3.48 | 3.73 |
| Michael Wuertz | NYY | mr | 29 | .778 | 171 | .333 | 142 | .493 | 142 | .493 | 39.0 | 5.3 | 4.74 | 4.50 |
| Tyler Yates | NYM | mr | 30 | .806 | 279 | .326 | 223 | .497 | 230 | .512 | 63.7 | 5.7 | 5.13 | 4.77 |
| Shane Youman* | StL | sp | 28 | .667 | 9 | .222 | 4 | .444 | 4 | .444 | 0.9 | 3.4 | 3.09 | 1.44 |
| Chris Young | Sea | sp | 29 | .675 | 492 | .266 | 332 | .427 | 339 | .436 | 83.6 | 4.1 | 3.74 | 3.56 |
| Carlos Zambrano | Det | sp | 27 | .725 | 621 | .274 | 447 | .456 | 457 | .466 | 112.6 | 4.5 | 4.07 | 4.16 |
| Victor Zambrano | Atl | mr | 32 | 1.169 | 8 | .250 | 11 | .733 | 12 | .800 | 4.2 | 12.6 | 11.36 | 12.01 |
| Barry Zito* | Ari | sp | 30 | .771 | 588 | .257 | 415 | .497 | 417 | .499 | 108.1 | 5.0 | 4.45 | 4.19 |
| Joel Zumaya | SD | mr | 23 | .802 | 15 | .400 | 10 | .476 | 10 | .476 | 2.7 | 5.1 | 4.63 | 4.36 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | PCH/G | STR% |
| David Aardsma | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.0 | .636 |
| Jeremy Accardo | Ari | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 19.8 | .645 |
| Manny Acosta | StL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.8 | .565 |
| Jeremy Affeldt* | Tam | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 13 | .317 | 22.7 | .578 |
| Jonathan Albaladejo | StL | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 22.8 | .630 |
| Matt Albers | Tam | sp | 25 | 26 | 0 | .000 | 0 | 7 | .269 | 120 | 4.6 | 34 | 10 | .294 | 78.1 | .600 |
| Greg Aquino | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 26.8 | .645 |
| Tony Armas | Col | mr | 30 | 21 | 1 | .048 | 1 | 6 | .286 | 83 | 4.0 | 18 | 6 | .333 | 101.5 | .608 |
| Bronson Arroyo | Atl | sp | 31 | 40 | 2 | .050 | 1 | 19 | .475 | 159 | 4.0 | 18 | 8 | .444 | 92.8 | .647 |
| Jose Ascanio | Ari | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 23.2 | .647 |
| Luis Ayala | LAD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 | 20.5 | .637 |
| Brandon Backe | NYY | sp | 30 | 6 | 0 | .000 | 0 | 5 | .833 | 31 | 5.2 | 6 | 4 | .667 | 108.0 | .585 |
| Mike Bacsik* | Atl | sp | 30 | 22 | 0 | .000 | 0 | 12 | .545 | 89 | 4.0 | 12 | 2 | .167 | 83.0 | .647 |
| Cha Seung Baek | StL | sp | 28 | 14 | 1 | .071 | 1 | 7 | .500 | 77 | 5.5 | 9 | 1 | .111 | 103.1 | .660 |
| Danys Baez | Pit | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 9 | .333 | 25.5 | .599 |
| Homer Bailey | LAD | sp | 22 | 10 | 0 | .000 | 0 | 4 | .400 | 33 | 3.3 | 9 | 5 | .556 | 93.5 | .529 |
| Scott Baker | NYM | sp | 26 | 23 | 3 | .130 | 2 | 15 | .652 | 72 | 3.1 | 10 | 5 | .500 | 81.1 | .671 |
| John Bale* | LAD | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 32.5 | .615 |
| Josh Banks | SF | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 18.0 | .667 |
| Brian Bannister | ChW | sp | 27 | 28 | 2 | .071 | 0 | 14 | .500 | 157 | 5.6 | 15 | 4 | .267 | 91.0 | .631 |
| Daniel Barone | Ari | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.0 | .711 |
| Miguel Batista | Was | sp | 37 | 31 | 2 | .065 | 2 | 14 | .452 | 136 | 4.4 | 25 | 7 | .280 | 92.8 | .607 |
| Yorman Bazardo | LAA | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 25.0 | .593 |
| Josh Beckett | Flo | sp | 28 | 31 | 5 | .161 | 2 | 18 | .581 | 124 | 4.0 | 9 | 4 | .444 | 101.6 | .673 |
| Erik Bedard* | Tor | sp | 29 | 36 | 8 | .222 | 3 | 25 | .694 | 171 | 4.8 | 16 | 4 | .250 | 113.5 | .638 |
| Joe Beimel* | ChC | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 18.4 | .628 |
| Matt Belisle | NYY | sp | 28 | 29 | 1 | .034 | 0 | 9 | .310 | 111 | 3.8 | 14 | 5 | .357 | 96.1 | .643 |
| Heath Bell | Ari | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 19.7 | .627 |
| Armando Benitez | Tam | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 24.5 | .615 |
| Jeff Bennett | Oak | sp | 28 | 3 | 0 | .000 | 0 | 1 | .333 | 11 | 3.7 | 2 | 1 | .500 | 92.0 | .641 |
| Joaquin Benoit | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 3 | .136 | 29.4 | .633 |
| Jason Bergmann | Cin | sp | 26 | 24 | 1 | .042 | 0 | 12 | .500 | 90 | 3.8 | 12 | 4 | .333 | 98.5 | .607 |
| Rafael Betancourt | ChW | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 20.3 | .724 |
| Chad Billingsley | Ari | mr | 23 | 27 | 0 | .000 | 0 | 12 | .444 | 130 | 4.8 | 14 | 1 | .071 | 90.9 | .601 |
| Kurt Birkins* | LAA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.0 | .583 |
| Travis Blackley* | Cin | sp | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 13 | 4.3 | 5 | 1 | .200 | 85.7 | .553 |
| Joe Blanton | NYY | sp | 27 | 32 | 0 | .000 | 0 | 17 | .531 | 109 | 3.4 | 19 | 10 | .526 | 101.6 | .671 |
| Jeremy Bonderman | LAD | sp | 25 | 31 | 1 | .032 | 0 | 15 | .484 | 136 | 4.4 | 17 | 9 | .529 | 97.5 | .663 |
| Boof Bonser | LAA | sp | 26 | 12 | 0 | .000 | 0 | 8 | .667 | 45 | 3.8 | 7 | 2 | .286 | 98.1 | .615 |
| Chris Booker | Phi | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 | 48.7 | .521 |
| Chris Bootcheck | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 23.5 | .636 |
| Dave Borkowski | Oak | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 24.7 | .592 |
| Joe Borowski | Sea | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 23.9 | .670 |
| Micah Bowie* | SD | mr | 33 | 9 | 0 | .000 | 0 | 5 | .556 | 58 | 6.4 | 11 | 2 | .182 | 81.3 | .605 |
| Blaine Boyer | Oak | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.7 | .610 |
| Dallas Braden* | Atl | sp | 24 | 12 | 0 | .000 | 0 | 5 | .417 | 64 | 5.3 | 10 | 3 | .300 | 77.6 | .636 |
| Chad Bradford | Ari | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 21.1 | .641 |
| Ryan Braun | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 37.9 | .594 |
| Chris Britton | Cin | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 20.2 | .597 |
| Lance Broadway | Flo | mr | 24 | 2 | 1 | .500 | 0 | 1 | .500 | 21 | 10.5 | 3 | 1 | .333 | 114.0 | .610 |
| Doug Brocail | Was | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 18.5 | .639 |
| Andrew Brown | Tam | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 31.1 | .616 |
| Jonathan Broxton | Flo | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 19.7 | .648 |
| Brian Bruney | Sea | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 23.8 | .571 |
| Clay Buchholz | Det | sp | 23 | 4 | 0 | .000 | 0 | 2 | .500 | 23 | 5.8 | 0 | 0 | .000 | 94.6 | .590 |
| Taylor Buchholz | Min | mr | 26 | 9 | 1 | .111 | 0 | 5 | .556 | 45 | 5.0 | 28 | 12 | .429 | 44.7 | .647 |
| Billy Buckner | Tex | sp | 24 | 6 | 1 | .167 | 0 | 1 | .167 | 27 | 4.5 | 2 | 0 | .000 | 102.8 | .595 |
| Mark Buehrle* | LAA | sp | 29 | 29 | 5 | .172 | 1 | 12 | .414 | 141 | 4.9 | 11 | 3 | .273 | 99.8 | .658 |
| Jason Bulger | ChC | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 34.4 | .581 |
| Bryan Bullington | Pit | sp | 27 | 6 | 0 | .000 | 0 | 2 | .333 | 19 | 3.2 | 9 | 1 | .111 | 60.0 | .614 |
| Ambiorix Burgos | Bos | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 | 23.8 | .578 |
| A.J. Burnett | Col | sp | 31 | 28 | 2 | .071 | 1 | 17 | .607 | 157 | 5.6 | 8 | 2 | .250 | 106.0 | .632 |
| Brian Burres* | Was | mr | 27 | 16 | 1 | .063 | 1 | 4 | .250 | 77 | 4.8 | 27 | 10 | .370 | 60.8 | .583 |
| Jared Burton | Bos | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 28.4 | .590 |
| Dave Bush | KC | sp | 28 | 35 | 1 | .029 | 0 | 14 | .400 | 139 | 4.0 | 33 | 16 | .485 | 93.7 | .623 |
| Paul Byrd | Pit | sp | 37 | 28 | 2 | .071 | 0 | 16 | .571 | 143 | 5.1 | 18 | 7 | .389 | 85.6 | .682 |
| Tim Byrdak* | Col | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 27.3 | .617 |
| Daniel Cabrera | Mil | sp | 27 | 33 | 1 | .030 | 0 | 19 | .576 | 133 | 4.0 | 21 | 9 | .429 | 100.4 | .606 |
| Fernando Cabrera | StL | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.0 | .556 |
| Matt Cain | SF | sp | 23 | 32 | 3 | .094 | 1 | 19 | .594 | 145 | 4.5 | 15 | 5 | .333 | 107.3 | .606 |
| Kiko Calero | ChW | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 27.6 | .584 |
| Kevin Cameron | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 16 | .348 | 36.4 | .578 |
| Shawn Camp | Hou | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 13 | .464 | 25.5 | .638 |
| Jose Capellan | Hou | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 21.4 | .631 |
| Matt Capps | Was | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 16.5 | .677 |
| Chris Capuano* | NYY | sp | 29 | 26 | 1 | .038 | 0 | 10 | .385 | 84 | 3.2 | 29 | 6 | .207 | 104.7 | .618 |
| Buddy Carlyle | Atl | sp | 30 | 20 | 0 | .000 | 0 | 10 | .500 | 80 | 4.0 | 11 | 5 | .455 | 91.3 | .628 |
| Fausto Carmona | SD | sp | 27 | 32 | 3 | .094 | 1 | 24 | .750 | 171 | 5.3 | 17 | 3 | .176 | 95.4 | .631 |
| Chris Carpenter | Min | sp | 33 | 2 | 0 | .000 | 0 | 0 | .000 | 10 | 5.0 | 3 | 0 | .000 | 72.0 | .618 |
| Marcos Carvajal | Oak | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 9.0 | .556 |
| Santiago Casilla | Col | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 26.7 | .605 |
| Jack Cassel | Tex | sp | 27 | 5 | 0 | .000 | 0 | 0 | .000 | 28 | 5.6 | 10 | 2 | .200 | 78.7 | .606 |
| Fabio Castro* | ChW | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 10.4 | .423 |
| Gustavo Chacin* | LAD | sp | 27 | 7 | 0 | .000 | 0 | 0 | .000 | 31 | 4.4 | 4 | 1 | .250 | 71.7 | .671 |
| Shawn Chacon | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 4 | .167 | 26.8 | .583 |
| Joba Chamberlain | Oak | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 25.6 | .607 |
| Rocky Cherry | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 18.7 | .604 |
| Matt Chico* | Det | sp | 25 | 32 | 0 | .000 | 0 | 6 | .188 | 209 | 6.5 | 38 | 20 | .526 | 82.2 | .598 |
| Vinnie Chulk | KC | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 3 | .120 | 22.8 | .628 |
| Roger Clemens | SD | sp | 45 | 20 | 0 | .000 | 0 | 14 | .700 | 155 | 7.8 | 8 | 1 | .125 | 96.6 | .637 |
| Tyler Clippard | Ari | sp | 23 | 6 | 0 | .000 | 0 | 2 | .333 | 33 | 5.5 | 8 | 2 | .250 | 85.3 | .586 |
| Todd Coffey | SF | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 23.6 | .615 |
| Jesus Colome | Pit | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 39 | 12 | .308 | 26.0 | .618 |
| Bartolo Colon | Tor | sp | 35 | 31 | 1 | .032 | 1 | 9 | .290 | 147 | 4.7 | 36 | 21 | .583 | 92.1 | .636 |
| Jose Contreras | Bal | sp | 36 | 29 | 3 | .103 | 0 | 10 | .345 | 116 | 4.0 | 24 | 12 | .500 | 96.3 | .618 |
| Aaron Cook | Atl | sp | 29 | 30 | 4 | .133 | 0 | 19 | .633 | 137 | 4.6 | 24 | 10 | .417 | 103.2 | .632 |
| Chad Cordero | SF | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 5 | .833 | 22.6 | .619 |
| Francisco Cordero | Oak | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 19.9 | .619 |
| Bryan Corey | Tam | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 32.9 | .565 |
| Lance Cormier | Flo | sp | 27 | 12 | 0 | .000 | 0 | 1 | .083 | 53 | 4.4 | 7 | 2 | .286 | 76.5 | .595 |
| Manny Corpas | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 16.4 | .677 |
| Kevin Correia | LAA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 23.1 | .624 |
| Neal Cotts* | Tam | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 25.4 | .578 |
| Jon Coutlangus* | Det | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 5 | .156 | 21.0 | .564 |
| Juan Cruz | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 7 | .212 | 25.5 | .594 |
| John Danks* | Col | sp | 23 | 29 | 1 | .034 | 0 | 9 | .310 | 152 | 5.2 | 20 | 8 | .400 | 97.4 | .625 |
| Kyle Davies | Cin | sp | 24 | 24 | 0 | .000 | 0 | 7 | .292 | 91 | 3.8 | 18 | 3 | .167 | 85.9 | .601 |
| Doug Davis* | StL | sp | 32 | 32 | 1 | .031 | 0 | 18 | .563 | 165 | 5.2 | 25 | 5 | .200 | 102.1 | .598 |
| Jorge De La Rosa* | Bos | sp | 27 | 27 | 0 | .000 | 0 | 3 | .111 | 119 | 4.4 | 31 | 11 | .355 | 67.6 | .632 |
| Manny Delcarmen | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 2 | .133 | 24.1 | .615 |
| Ryan Dempster | Min | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 20.1 | .597 |
| Julio DePaula | NYY | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 32.0 | .631 |
| Matt DeSalvo | Phi | sp | 27 | 7 | 1 | .143 | 0 | 1 | .143 | 23 | 3.3 | 10 | 6 | .600 | 96.4 | .566 |
| Ross Detwiler* | Tex | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 27.0 | .667 |
| Joey Devine | Hou | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 22.0 | .507 |
| Lenny DiNardo* | Tam | sp | 28 | 28 | 1 | .036 | 1 | 14 | .500 | 135 | 4.8 | 20 | 8 | .400 | 91.3 | .603 |
| Scott Dohmann | KC | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 25.4 | .588 |
| Brendan Donnelly | Tor | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 25.7 | .618 |
| Octavio Dotel | Ari | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.8 | .693 |
| Scott Downs* | LAA | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 4 | .167 | 19.1 | .610 |
| Brandon Duckworth | Was | mr | 32 | 2 | 0 | .000 | 0 | 0 | .000 | 14 | 7.0 | 20 | 4 | .200 | 31.8 | .590 |
| Zach Duke* | Oak | sp | 25 | 21 | 0 | .000 | 0 | 8 | .381 | 79 | 3.8 | 20 | 8 | .400 | 90.0 | .625 |
| Phil Dumatrait* | NYM | sp | 26 | 3 | 0 | .000 | 0 | 0 | .000 | 6 | 2.0 | 6 | 1 | .167 | 66.0 | .510 |
| Chad Durbin | Bos | sp | 30 | 27 | 0 | .000 | 0 | 9 | .333 | 110 | 4.1 | 33 | 12 | .364 | 90.1 | .611 |
| J.D. Durbin | SF | sp | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 33 | 5.5 | 5 | 2 | .400 | 79.9 | .562 |
| Adam Eaton | Bal | sp | 30 | 22 | 0 | .000 | 0 | 5 | .227 | 86 | 3.9 | 26 | 13 | .500 | 84.0 | .565 |
| Scott Elarton | Mil | sp | 32 | 8 | 0 | .000 | 0 | 0 | .000 | 19 | 2.4 | 4 | 1 | .250 | 60.9 | .567 |
| Alan Embree* | Bos | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 14 | .350 | 17.7 | .672 |
| Kelvim Escobar | Bal | sp | 32 | 33 | 7 | .212 | 2 | 28 | .848 | 115 | 3.5 | 12 | 3 | .250 | 103.9 | .621 |
| Dana Eveland* | KC | mr | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 5 | 2.5 | 2 | 0 | .000 | 70.5 | .539 |
| Scott Eyre* | Was | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 20.8 | .547 |
| Kyle Farnsworth | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 | 24.3 | .629 |
| Scott Feldman | Tex | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 15 | .600 | 33.2 | .536 |
| Pedro Feliciano* | Oak | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 | 25.6 | .602 |
| Randy Flores* | Ari | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 16.8 | .654 |
| Ron Flores* | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 26.0 | .731 |
| Gavin Floyd | LAA | sp | 25 | 4 | 0 | .000 | 0 | 2 | .500 | 21 | 5.3 | 0 | 0 | .000 | 84.3 | .629 |
| Josh Fogg | Ari | sp | 31 | 19 | 0 | .000 | 0 | 5 | .263 | 82 | 4.3 | 20 | 5 | .250 | 79.4 | .623 |
| Casey Fossum* | Pit | mr | 30 | 20 | 0 | .000 | 0 | 3 | .150 | 108 | 5.4 | 26 | 14 | .538 | 70.8 | .653 |
| Jeff Francis* | LAD | sp | 27 | 34 | 4 | .118 | 2 | 21 | .618 | 159 | 4.7 | 22 | 6 | .273 | 98.9 | .632 |
| Frank Francisco | Min | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 19.6 | .571 |
| Ryan Franklin | ChC | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 18.4 | .669 |
| Jason Frasor | StL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 20.8 | .650 |
| Brian Fuentes* | Tor | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 22.7 | .590 |
| Aaron Fultz* | Tex | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 13 | .302 | 25.1 | .595 |
| Kason Gabbard* | LAD | sp | 26 | 18 | 2 | .111 | 0 | 11 | .611 | 69 | 3.8 | 10 | 1 | .100 | 95.8 | .596 |
| Eric Gagne | NYM | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 | 20.0 | .624 |
| Armando Galarraga | KC | mr | 26 | 19 | 0 | .000 | 0 | 5 | .263 | 57 | 3.0 | 9 | 3 | .333 | 89.2 | .553 |
| Sean Gallagher | Tex | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 | 40.0 | .488 |
| Yovani Gallardo | StL | sp | 22 | 20 | 3 | .150 | 1 | 13 | .650 | 88 | 4.4 | 12 | 6 | .500 | 108.4 | .623 |
| Freddy Garcia | Det | sp | 32 | 3 | 0 | .000 | 0 | 1 | .333 | 18 | 6.0 | 3 | 1 | .333 | 82.0 | .634 |
| Harvey Garcia | SF | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 10.0 | .700 |
| Lee Gardner | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 20.7 | .660 |
| Jon Garland | Pit | sp | 28 | 32 | 5 | .156 | 0 | 24 | .750 | 171 | 5.3 | 16 | 7 | .438 | 94.1 | .644 |
| Matt Garza | Oak | sp | 24 | 17 | 2 | .118 | 0 | 8 | .471 | 78 | 4.6 | 12 | 6 | .500 | 102.7 | .627 |
| Chad Gaudin | NYM | sp | 25 | 34 | 1 | .029 | 1 | 18 | .529 | 126 | 3.7 | 25 | 5 | .200 | 94.9 | .595 |
| Geoff Geary | Flo | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 7 | .241 | 28.6 | .619 |
| Justin Germano | StL | sp | 25 | 25 | 0 | .000 | 0 | 16 | .640 | 90 | 3.6 | 19 | 6 | .316 | 94.0 | .627 |
| Tom Glavine* | ChC | sp | 42 | 27 | 2 | .074 | 1 | 9 | .333 | 199 | 7.4 | 27 | 14 | .519 | 86.8 | .623 |
| Gary Glover | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 8 | .276 | 22.7 | .632 |
| Jimmy Gobble* | Flo | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 7 | .500 | 20.0 | .620 |
| Edgar Gonzalez | Col | mr | 25 | 18 | 3 | .167 | 0 | 10 | .556 | 77 | 4.3 | 16 | 10 | .625 | 101.9 | .634 |
| Mike Gonzalez* | Atl | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 24.6 | .561 |
| Tom Gordon | Phi | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 7 | .467 | 28.0 | .594 |
| Tom Gorzelanny* | Pit | sp | 25 | 33 | 0 | .000 | 0 | 16 | .485 | 136 | 4.1 | 27 | 8 | .296 | 94.2 | .614 |
| John Grabow* | Bal | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 21 | .618 | 27.0 | .604 |
| Sean Green | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 4 | .154 | 20.0 | .601 |
| Kevin Gregg | Det | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 10 | .323 | 24.6 | .584 |
| Zack Greinke | LAA | mr | 24 | 31 | 2 | .065 | 2 | 17 | .548 | 175 | 5.6 | 16 | 6 | .375 | 96.5 | .649 |
| Jason Grilli | Phi | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 9 | .290 | 22.0 | .617 |
| Eddie Guardado* | Mil | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 20.8 | .602 |
| Matt Guerrier | Sea | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 1 | .056 | 21.8 | .653 |
| Jeremy Guthrie | Min | sp | 29 | 29 | 4 | .138 | 2 | 21 | .724 | 138 | 4.8 | 17 | 3 | .176 | 94.9 | .641 |
| Juan Gutierrez | SD | mr | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 21 | 7.0 | 0 | 0 | .000 | 70.3 | .701 |
| Roy Halladay | Hou | sp | 31 | 32 | 11 | .344 | 2 | 21 | .656 | 170 | 5.3 | 16 | 6 | .375 | 105.4 | .673 |
| Cole Hamels* | Flo | sp | 24 | 29 | 0 | .000 | 0 | 21 | .724 | 116 | 4.0 | 14 | 1 | .071 | 97.7 | .656 |
| Jason Hammel | Sea | sp | 25 | 1 | 0 | .000 | 0 | 1 | 1.000 | 7 | 7.0 | 4 | 1 | .250 | 28.9 | .644 |
| Justin Hampson* | SD | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 2 | .118 | 18.7 | .649 |
| Joel Hanrahan | NYM | sp | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 6 | 1.5 | 1 | 0 | .000 | 55.8 | .556 |
| Aaron Harang | Cle | sp | 30 | 34 | 3 | .088 | 2 | 18 | .529 | 195 | 5.7 | 24 | 8 | .333 | 111.2 | .646 |
| Rich Harden | Col | sp | 26 | 4 | 0 | .000 | 0 | 2 | .500 | 7 | 1.8 | 2 | 1 | .500 | 99.3 | .657 |
| Dan Haren | LAA | sp | 27 | 33 | 3 | .091 | 1 | 23 | .697 | 138 | 4.2 | 17 | 7 | .412 | 103.7 | .657 |
| Kevin Hart | LAA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 28.9 | .589 |
| LaTroy Hawkins | Tex | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 20.8 | .631 |
| Aaron Heilman | Hou | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 23.4 | .651 |
| Mark Hendrickson* | Sea | mr | 34 | 18 | 0 | .000 | 0 | 6 | .333 | 116 | 6.4 | 17 | 7 | .412 | 55.7 | .645 |
| Sean Henn* | Flo | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 16.0 | .625 |
| Brad Hennessey | Flo | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 7 | .350 | 26.0 | .602 |
| Clay Hensley | Ari | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 32.5 | .581 |
| Matt Herges | Pit | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 20.1 | .645 |
| Felix Hernandez | Bal | sp | 22 | 34 | 1 | .029 | 0 | 18 | .529 | 173 | 5.1 | 24 | 6 | .250 | 101.5 | .644 |
| Livan Hernandez | Atl | sp | 33 | 38 | 3 | .079 | 0 | 18 | .474 | 175 | 4.6 | 21 | 8 | .381 | 90.6 | .586 |
| Orlando Hernandez | ChC | sp | 38 | 26 | 2 | .077 | 0 | 17 | .654 | 168 | 6.5 | 13 | 3 | .231 | 95.9 | .597 |
| Roberto Hernandez | Atl | mr | 43 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 22.6 | .618 |
| Rich Hill* | ChC | sp | 28 | 31 | 1 | .032 | 0 | 19 | .613 | 143 | 4.6 | 17 | 3 | .176 | 99.4 | .608 |
| Shawn Hill | Tam | sp | 27 | 21 | 1 | .048 | 1 | 10 | .476 | 90 | 4.3 | 14 | 7 | .500 | 101.8 | .632 |
| Jason Hirsh | Ari | sp | 26 | 18 | 0 | .000 | 0 | 6 | .333 | 99 | 5.5 | 7 | 4 | .571 | 92.0 | .612 |
| Luke Hochevar | Mil | mr | 24 | 1 | 0 | .000 | 0 | 1 | 1.000 | 9 | 9.0 | 0 | 0 | .000 | 47.7 | .594 |
| Jim Hoey | NYM | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 | 22.9 | .523 |
| Trevor Hoffman | SD | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 | 20.1 | .663 |
| D.J. Houlton | Flo | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 5 | 1.000 | 31.0 | .661 |
| J.P. Howell* | Flo | sp | 25 | 8 | 0 | .000 | 0 | 0 | .000 | 53 | 6.6 | 10 | 4 | .400 | 76.3 | .623 |
| Bob Howry | ChC | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 24.4 | .643 |
| Tim Hudson | Min | sp | 32 | 34 | 5 | .147 | 2 | 21 | .618 | 161 | 4.7 | 21 | 13 | .619 | 103.4 | .644 |
| Phil Hughes | SF | sp | 22 | 16 | 2 | .125 | 1 | 10 | .625 | 60 | 3.8 | 10 | 3 | .300 | 101.2 | .611 |
| Philip Humber | LAA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 16.0 | .563 |
| Kei Igawa* | KC | sp | 28 | 33 | 0 | .000 | 0 | 10 | .303 | 145 | 4.4 | 33 | 18 | .545 | 90.3 | .582 |
| Jason Isringhausen | LAA | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 18.6 | .607 |
| Edwin Jackson | Hou | sp | 24 | 33 | 0 | .000 | 0 | 15 | .455 | 165 | 5.0 | 25 | 11 | .440 | 87.3 | .604 |
| Chuck James* | ChW | sp | 26 | 25 | 0 | .000 | 0 | 11 | .440 | 144 | 5.8 | 15 | 6 | .400 | 85.1 | .603 |
| Casey Janssen | LAA | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 13 | .419 | 22.8 | .620 |
| Bobby Jenks | Pit | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 18.5 | .696 |
| Jason Jennings | Cle | sp | 29 | 9 | 1 | .111 | 1 | 4 | .444 | 50 | 5.6 | 9 | 3 | .333 | 89.9 | .625 |
| Ubaldo Jimenez | NYY | sp | 24 | 15 | 0 | .000 | 0 | 4 | .267 | 47 | 3.1 | 11 | 6 | .545 | 100.5 | .601 |
| Josh Johnson | NYY | sp | 24 | 5 | 0 | .000 | 0 | 0 | .000 | 25 | 5.0 | 5 | 5 | 1.000 | 65.0 | .560 |
| Randy Johnson* | NYM | sp | 44 | 13 | 1 | .077 | 0 | 9 | .692 | 32 | 2.5 | 7 | 3 | .429 | 98.5 | .648 |
| Tyler Johnson* | Cle | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 18.6 | .625 |
| Todd Jones | ChC | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 24.3 | .635 |
| Jorge Julio | Phi | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 31.3 | .595 |
| Jair Jurrjens | Mil | sp | 22 | 5 | 0 | .000 | 0 | 4 | .800 | 8 | 1.6 | 1 | 0 | .000 | 67.9 | .638 |
| Jeff Karstens | Cin | mr | 25 | 4 | 0 | .000 | 0 | 0 | .000 | 29 | 7.3 | 5 | 3 | .600 | 53.0 | .506 |
| Scott Kazmir* | SF | sp | 24 | 34 | 1 | .029 | 0 | 21 | .618 | 148 | 4.4 | 17 | 3 | .176 | 103.2 | .614 |
| Kyle Kendrick | LAD | sp | 23 | 21 | 2 | .095 | 0 | 8 | .381 | 105 | 5.0 | 14 | 2 | .143 | 87.1 | .647 |
| Ian Kennedy | Phi | sp | 23 | 4 | 0 | .000 | 0 | 2 | .500 | 12 | 3.0 | 5 | 3 | .600 | 111.8 | .611 |
| Joe Kennedy* | Phi | mr | 29 | 25 | 0 | .000 | 0 | 5 | .200 | 145 | 5.8 | 33 | 14 | .424 | 89.2 | .602 |
| Logan Kensing | Mil | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.8 | .626 |
| Byung-Hyun Kim | Tam | sp | 29 | 14 | 0 | .000 | 0 | 2 | .143 | 65 | 4.6 | 16 | 3 | .188 | 63.8 | .568 |
| Ray King* | KC | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 17 | .395 | 21.3 | .545 |
| Steve Kline* | StL | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 21.1 | .621 |
| Mike Koplove | Col | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 12.3 | .531 |
| Hong-Chih Kuo* | Sea | sp | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 1 | 0 | .000 | 31.8 | .567 |
| John Lackey | Hou | sp | 29 | 34 | 3 | .088 | 0 | 22 | .647 | 167 | 4.9 | 23 | 12 | .522 | 107.2 | .654 |
| Aaron Laffey* | ChW | sp | 23 | 10 | 2 | .200 | 2 | 5 | .500 | 63 | 6.3 | 5 | 3 | .600 | 90.6 | .655 |
| John Lannan* | Mil | sp | 23 | 6 | 0 | .000 | 0 | 1 | .167 | 34 | 5.7 | 8 | 1 | .125 | 97.7 | .558 |
| Brian Lawrence | Phi | sp | 32 | 6 | 0 | .000 | 0 | 0 | .000 | 29 | 4.8 | 6 | 4 | .667 | 98.5 | .570 |
| Cliff Lee* | Cle | sp | 29 | 19 | 0 | .000 | 0 | 4 | .211 | 115 | 6.1 | 19 | 8 | .421 | 86.3 | .602 |
| Jon Lester* | Sea | sp | 24 | 15 | 1 | .067 | 0 | 6 | .400 | 87 | 5.8 | 14 | 3 | .214 | 91.4 | .596 |
| Jensen Lewis | Min | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 21.3 | .611 |
| Brad Lidge | Atl | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 20.3 | .632 |
| Jon Lieber | Phi | sp | 38 | 13 | 2 | .154 | 0 | 4 | .308 | 70 | 5.4 | 12 | 6 | .500 | 97.2 | .641 |
| Ted Lilly* | Hou | sp | 32 | 33 | 4 | .121 | 3 | 23 | .697 | 165 | 5.0 | 14 | 7 | .500 | 98.8 | .647 |
| Tim Lincecum | Tor | sp | 24 | 27 | 1 | .037 | 0 | 13 | .481 | 91 | 3.4 | 27 | 5 | .185 | 99.3 | .613 |
| Matt Lindstrom | Bos | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 23.1 | .614 |
| Scott Linebrink | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 11 | .393 | 20.4 | .628 |
| Jesse Litsch | Cin | sp | 23 | 16 | 0 | .000 | 0 | 12 | .750 | 91 | 5.7 | 13 | 5 | .385 | 96.3 | .631 |
| Wes Littleton | Cin | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 19.0 | .619 |
| Bobby Livingston* | Col | sp | 25 | 28 | 2 | .071 | 0 | 9 | .321 | 151 | 5.4 | 19 | 6 | .316 | 89.1 | .687 |
| Radhames Liz | Bal | mr | 25 | 6 | 0 | .000 | 0 | 1 | .167 | 19 | 3.2 | 11 | 0 | .000 | 64.2 | .509 |
| Esteban Loaiza | Flo | sp | 36 | 8 | 0 | .000 | 0 | 0 | .000 | 46 | 5.8 | 4 | 2 | .500 | 71.5 | .549 |
| Kameron Loe | Bos | sp | 26 | 28 | 0 | .000 | 0 | 6 | .214 | 129 | 4.6 | 34 | 12 | .353 | 77.2 | .616 |
| Adam Loewen* | LAA | sp | 24 | 3 | 0 | .000 | 0 | 1 | .333 | 9 | 3.0 | 1 | 0 | .000 | 101.7 | .554 |
| Boone Logan* | Cle | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 24.1 | .585 |
| Kyle Lohse | Bal | sp | 29 | 31 | 3 | .097 | 0 | 17 | .548 | 126 | 4.1 | 23 | 6 | .261 | 100.3 | .608 |
| Braden Looper | Cle | sp | 33 | 32 | 6 | .188 | 1 | 15 | .469 | 241 | 7.5 | 24 | 10 | .417 | 102.1 | .640 |
| Aquilino Lopez | Sea | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 8.5 | .824 |
| Javier Lopez* | Col | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 | 19.7 | .592 |
| Rodrigo Lopez | StL | sp | 32 | 17 | 1 | .059 | 0 | 12 | .706 | 64 | 3.8 | 9 | 0 | .000 | 100.2 | .649 |
| Derek Lowe | ChW | sp | 35 | 32 | 4 | .125 | 1 | 19 | .594 | 150 | 4.7 | 24 | 7 | .292 | 104.2 | .622 |
| Mark Lowe | StL | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 25.3 | .526 |
| Noah Lowry* | Mil | sp | 27 | 28 | 0 | .000 | 0 | 14 | .500 | 102 | 3.6 | 31 | 8 | .258 | 99.4 | .575 |
| Ruddy Lugo | KC | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 8 | .348 | 33.4 | .586 |
| Brandon Lyon | Tam | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 6 | .154 | 21.8 | .613 |
| Mike MacDougal | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 1 | .067 | 23.6 | .575 |
| Greg Maddux | ChC | sp | 42 | 35 | 1 | .029 | 1 | 20 | .571 | 203 | 5.8 | 17 | 7 | .412 | 88.6 | .679 |
| Ryan Madson | NYM | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 27.0 | .635 |
| Ron Mahay* | Det | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 50 | 11 | .220 | 21.2 | .563 |
| Paul Maholm* | LAA | sp | 26 | 24 | 1 | .042 | 0 | 13 | .542 | 94 | 3.9 | 16 | 5 | .313 | 92.6 | .636 |
| John Maine | Oak | sp | 27 | 33 | 3 | .091 | 0 | 22 | .667 | 154 | 4.7 | 14 | 6 | .429 | 96.3 | .617 |
| Gary Majewski | Tex | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 29.7 | .678 |
| Shaun Marcum | Tam | sp | 26 | 30 | 2 | .067 | 2 | 22 | .733 | 137 | 4.6 | 18 | 1 | .056 | 100.4 | .640 |
| Carlos Marmol | Tam | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 23.4 | .584 |
| Jason Marquis | StL | sp | 29 | 30 | 1 | .033 | 0 | 16 | .533 | 137 | 4.6 | 18 | 3 | .167 | 102.7 | .607 |
| Jay Marshall* | Det | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 22.3 | .569 |
| Sean Marshall* | Flo | sp | 25 | 24 | 1 | .042 | 0 | 12 | .500 | 106 | 4.4 | 13 | 4 | .308 | 95.0 | .625 |
| Damaso Marte* | Ari | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 10 | .323 | 17.6 | .605 |
| Tom Martin* | Atl | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 15 | .417 | 25.0 | .600 |
| Carlos Martinez | Cin | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.0 | .553 |
| Pedro Martinez | Bos | sp | 36 | 6 | 0 | .000 | 0 | 3 | .500 | 32 | 5.3 | 3 | 1 | .333 | 95.5 | .639 |
| Nick Masset | Oak | mr | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 25 | 12.5 | 2 | 0 | .000 | 77.5 | .555 |
| Tom Mastny | KC | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 34.5 | .604 |
| Julio Mateo | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 24.0 | .625 |
| Daisuke Matsuzaka | Cle | sp | 27 | 32 | 1 | .031 | 1 | 20 | .625 | 193 | 6.0 | 34 | 12 | .353 | 113.4 | .611 |
| Marcus McBeth | Bos | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 15.5 | .516 |
| Macay McBride* | Ari | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 15.1 | .578 |
| Brandon McCarthy | Ari | sp | 24 | 8 | 0 | .000 | 0 | 4 | .500 | 25 | 3.1 | 8 | 2 | .250 | 93.4 | .614 |
| Seth McClung | Mil | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 | 28.1 | .553 |
| Dustin McGowan | Sea | sp | 26 | 30 | 2 | .067 | 1 | 21 | .700 | 229 | 7.6 | 27 | 11 | .407 | 104.7 | .619 |
| Marty McLeary | NYM | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 18.0 | .611 |
| Mark McLemore* | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 31.8 | .580 |
| Gil Meche | Sea | sp | 29 | 34 | 4 | .118 | 1 | 23 | .676 | 185 | 5.4 | 18 | 10 | .556 | 100.8 | .645 |
| Brandon Medders | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 23.4 | .615 |
| Luis Mendoza | Mil | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 28.3 | .665 |
| Cla Meredith | Col | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 8 | .308 | 18.9 | .674 |
| Jose Mesa | NYM | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 25.0 | .568 |
| Randy Messenger | Phi | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 7 | .241 | 25.3 | .635 |
| Dan Meyer* | Oak | sp | 26 | 6 | 0 | .000 | 0 | 0 | .000 | 38 | 6.3 | 11 | 1 | .091 | 86.4 | .557 |
| Andrew Miller* | Mil | sp | 23 | 13 | 0 | .000 | 0 | 0 | .000 | 54 | 4.2 | 14 | 7 | .500 | 87.7 | .557 |
| Justin Miller | LAD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 24.8 | .615 |
| Trever Miller* | Phi | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 30.0 | .569 |
| Kevin Millwood | StL | sp | 33 | 23 | 0 | .000 | 0 | 14 | .609 | 104 | 4.5 | 12 | 6 | .500 | 102.7 | .647 |
| Zach Miner | Pit | mr | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 6 | 4 | .667 | 30.4 | .624 |
| Patrick Misch* | NYM | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 3 | 2 | .667 | 28.0 | .629 |
| Sergio Mitre | Cin | sp | 27 | 26 | 1 | .038 | 1 | 15 | .577 | 100 | 3.8 | 21 | 4 | .190 | 87.0 | .625 |
| Brian Moehler | Tor | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 7 | .250 | 32.8 | .646 |
| Franklin Morales* | Flo | sp | 22 | 11 | 0 | .000 | 0 | 5 | .455 | 49 | 4.5 | 4 | 0 | .000 | 92.2 | .619 |
| Juan Morillo | Bos | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 2.0 | 1.000 |
| Matt Morris | Oak | sp | 33 | 34 | 2 | .059 | 0 | 18 | .529 | 145 | 4.3 | 25 | 6 | .240 | 102.5 | .630 |
| Brandon Morrow | LAA | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 18.3 | .562 |
| Dustin Moseley | Was | mr | 26 | 7 | 1 | .143 | 1 | 6 | .857 | 25 | 3.6 | 5 | 0 | .000 | 39.1 | .634 |
| Guillermo Mota | Bal | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 1 | .056 | 27.5 | .615 |
| Jamie Moyer* | Phi | sp | 45 | 34 | 6 | .176 | 1 | 13 | .382 | 164 | 4.8 | 21 | 9 | .429 | 104.2 | .643 |
| Peter Moylan | Cin | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 21.2 | .643 |
| Arnie Munoz* | Phi | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 36.4 | .495 |
| A.J. Murray* | Det | mr | 26 | 3 | 0 | .000 | 0 | 1 | .333 | 20 | 6.7 | 8 | 2 | .250 | 31.4 | .565 |
| Mike Mussina | SD | sp | 39 | 30 | 0 | .000 | 0 | 9 | .300 | 180 | 6.0 | 21 | 7 | .333 | 81.9 | .647 |
| Brett Myers | LAA | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 12 | .429 | 24.6 | .588 |
| Mike Myers* | Tex | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 24.0 | .607 |
| Joe Nathan | ChW | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 14.4 | .686 |
| Pat Neshek | Ari | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 19.5 | .619 |
| Dustin Nippert | ChW | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 5 | .833 | 43.9 | .617 |
| Ricky Nolasco | Cin | sp | 25 | 4 | 0 | .000 | 0 | 2 | .500 | 15 | 3.8 | 3 | 0 | .000 | 101.8 | .624 |
| Leo Nunez | NYM | mr | 24 | 7 | 0 | .000 | 0 | 4 | .571 | 15 | 2.1 | 4 | 1 | .250 | 59.2 | .664 |
| Eric O'Flaherty* | NYM | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 12 | .400 | 22.5 | .612 |
| Tomo Ohka | Mil | sp | 32 | 11 | 0 | .000 | 0 | 9 | .818 | 49 | 4.5 | 10 | 4 | .400 | 89.4 | .630 |
| Ross Ohlendorf | NYM | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 16.3 | .585 |
| Will Ohman* | StL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 16.0 | .622 |
| Hideki Okajima* | SD | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 19.3 | .636 |
| Darren Oliver* | Cle | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 22.8 | .597 |
| Scott Olsen* | Hou | sp | 24 | 4 | 0 | .000 | 0 | 0 | .000 | 26 | 6.5 | 9 | 5 | .556 | 79.3 | .612 |
| Garrett Olson* | Was | sp | 24 | 4 | 0 | .000 | 0 | 1 | .250 | 15 | 3.8 | 7 | 5 | .714 | 68.3 | .535 |
| Ramon Ortiz | Pit | mr | 35 | 23 | 1 | .043 | 0 | 12 | .522 | 122 | 5.3 | 15 | 5 | .333 | 81.6 | .673 |
| Russ Ortiz | StL | sp | 34 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 0 | 0 | .000 | 60.0 | .600 |
| Chad Orvella | Col | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.0 | .526 |
| Franquelis Osoria | Tex | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 27.6 | .606 |
| Roy Oswalt | Ari | sp | 30 | 32 | 2 | .063 | 1 | 15 | .469 | 134 | 4.2 | 25 | 11 | .440 | 98.4 | .628 |
| Akinori Otsuka | Tex | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 19.1 | .638 |
| Henry Owens | NYY | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 19.1 | .624 |
| Micah Owings | LAA | sp | 25 | 26 | 0 | .000 | 0 | 15 | .577 | 131 | 5.0 | 17 | 2 | .118 | 97.9 | .613 |
| Vicente Padilla | Flo | sp | 30 | 26 | 0 | .000 | 0 | 13 | .500 | 123 | 4.7 | 26 | 5 | .192 | 91.9 | .620 |
| Jonathan Papelbon | LAD | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.8 | .645 |
| Manny Parra* | Hou | mr | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 9 | 3.0 | 4 | 0 | .000 | 91.0 | .604 |
| John Parrish* | Min | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 14 | .326 | 14.3 | .547 |
| Troy Patton* | Cle | sp | 22 | 3 | 0 | .000 | 0 | 0 | .000 | 22 | 7.3 | 3 | 3 | 1.000 | 97.0 | .608 |
| Felipe Paulino | Mil | sp | 24 | 3 | 0 | .000 | 0 | 0 | .000 | 3 | 1.0 | 1 | 1 | 1.000 | 77.3 | .621 |
| Carl Pavano | NYY | sp | 32 | 3 | 0 | .000 | 0 | 2 | .667 | 4 | 1.3 | 3 | 2 | .667 | 95.7 | .610 |
| Jake Peavy | SD | sp | 27 | 34 | 3 | .088 | 3 | 27 | .794 | 206 | 6.1 | 19 | 8 | .421 | 108.8 | .638 |
| Mike Pelfrey | NYM | sp | 24 | 15 | 1 | .067 | 0 | 6 | .400 | 38 | 2.5 | 21 | 8 | .381 | 76.2 | .567 |
| Tony Pena | SF | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 8 | .444 | 23.1 | .612 |
| Brad Penny | Tam | sp | 30 | 30 | 1 | .033 | 0 | 14 | .467 | 141 | 4.7 | 35 | 14 | .400 | 97.3 | .612 |
| Joel Peralta | Tam | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 30.7 | .679 |
| Troy Percival | SD | mr | 38 | 2 | 0 | .000 | 0 | 2 | 1.000 | 14 | 7.0 | 12 | 0 | .000 | 27.9 | .618 |
| Odalis Perez* | Cin | sp | 31 | 29 | 1 | .034 | 0 | 19 | .655 | 99 | 3.4 | 23 | 11 | .478 | 91.8 | .623 |
| Oliver Perez* | Min | sp | 26 | 32 | 0 | .000 | 0 | 13 | .406 | 160 | 5.0 | 28 | 10 | .357 | 103.7 | .588 |
| Rafael Perez* | NYY | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 21.1 | .687 |
| Glen Perkins* | Pit | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 24.4 | .598 |
| Yusmeiro Petit | Tam | sp | 23 | 13 | 0 | .000 | 0 | 3 | .231 | 72 | 5.5 | 17 | 3 | .176 | 79.2 | .640 |
| Billy Petrick | Min | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 8.0 | .500 |
| Andy Pettitte* | Tex | sp | 36 | 35 | 4 | .114 | 1 | 15 | .429 | 153 | 4.4 | 27 | 11 | .407 | 107.3 | .620 |
| Joel Pineiro | Bal | mr | 29 | 7 | 0 | .000 | 0 | 3 | .429 | 28 | 4.0 | 16 | 6 | .375 | 32.4 | .626 |
| Renyel Pinto* | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 48 | 6 | .125 | 23.8 | .548 |
| Sidney Ponson | Flo | sp | 31 | 2 | 0 | .000 | 0 | 0 | .000 | 18 | 9.0 | 2 | 2 | 1.000 | 51.5 | .660 |
| Scott Proctor | LAA | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 24.0 | .589 |
| J.J. Putz | SD | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 14.4 | .669 |
| Chad Qualls | LAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 23.4 | .639 |
| Edwar Ramirez | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 23.1 | .611 |
| Elizardo Ramirez | Phi | sp | 25 | 4 | 1 | .250 | 0 | 1 | .250 | 11 | 2.8 | 5 | 1 | .200 | 106.8 | .597 |
| Horacio Ramirez* | KC | sp | 28 | 33 | 0 | .000 | 0 | 11 | .333 | 128 | 3.9 | 29 | 6 | .207 | 77.9 | .595 |
| Ramon Ramirez | Col | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 21.8 | .635 |
| Darrell Rasner | Tex | sp | 27 | 7 | 0 | .000 | 0 | 0 | .000 | 36 | 5.1 | 4 | 3 | .750 | 91.1 | .603 |
| Jon Rauch | ChW | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 10 | .455 | 23.4 | .651 |
| Chris Ray | Flo | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 19.0 | .650 |
| Tim Redding | SF | sp | 30 | 18 | 0 | .000 | 0 | 9 | .500 | 67 | 3.7 | 20 | 6 | .300 | 102.3 | .590 |
| Mark Redman* | ChC | sp | 34 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 3 | 1 | .333 | 48.5 | .619 |
| Al Reyes | Flo | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 21.7 | .624 |
| Anthony Reyes | Hou | sp | 26 | 23 | 0 | .000 | 0 | 9 | .391 | 112 | 4.9 | 16 | 1 | .063 | 87.5 | .614 |
| Dennys Reyes* | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 24.1 | .511 |
| Jo-Jo Reyes* | Ari | sp | 23 | 10 | 0 | .000 | 0 | 5 | .500 | 62 | 6.2 | 10 | 8 | .800 | 93.7 | .565 |
| John Rheinecker* | StL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 14.1 | .515 |
| Juan Rincon | Tex | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 25.8 | .593 |
| David Riske | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 19.5 | .619 |
| Mariano Rivera | Flo | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 17.1 | .669 |
| Saul Rivera | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 6 | .188 | 21.4 | .580 |
| Nate Robertson* | Was | sp | 30 | 32 | 0 | .000 | 0 | 23 | .719 | 175 | 5.5 | 16 | 9 | .563 | 92.2 | .623 |
| Fernando Rodney | KC | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 19.2 | .617 |
| Francisco Rodriguez | Col | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 20.6 | .609 |
| Wandy Rodriguez* | Min | sp | 29 | 32 | 3 | .094 | 2 | 17 | .531 | 182 | 5.7 | 35 | 8 | .229 | 89.4 | .610 |
| Kenny Rogers* | NYM | sp | 43 | 14 | 0 | .000 | 0 | 7 | .500 | 32 | 2.3 | 13 | 7 | .538 | 92.3 | .615 |
| J.C. Romero* | Was | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 11 | .393 | 19.7 | .543 |
| Ryan Rowland-Smith* | SF | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 19.3 | .608 |
| Jae Kuk Ryu | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 16.6 | .482 |
| Kirk Saarloos | Phi | mr | 29 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 18 | 7 | .389 | 36.4 | .570 |
| C.C. Sabathia* | ChW | sp | 27 | 34 | 3 | .088 | 1 | 20 | .588 | 148 | 4.4 | 20 | 5 | .250 | 96.1 | .687 |
| Takashi Saito | SD | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 20.7 | .651 |
| Juan Salas | NYY | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 24.6 | .597 |
| Brad Salmon | Bal | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 23.7 | .616 |
| Chris Sampson | Min | sp | 30 | 22 | 1 | .045 | 0 | 9 | .409 | 132 | 6.0 | 19 | 6 | .316 | 76.6 | .630 |
| Anibal Sanchez | Bos | sp | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 0 | 0 | .000 | 51.5 | .573 |
| Jonathan Sanchez* | KC | mr | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 0 | 0.0 | 0 | 0 | .000 | 88.0 | .585 |
| Romulo Sanchez | Col | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 24.9 | .598 |
| Ervin Santana | Bos | sp | 25 | 29 | 0 | .000 | 0 | 9 | .310 | 112 | 3.9 | 25 | 10 | .400 | 90.8 | .619 |
| Johan Santana* | Mil | sp | 29 | 29 | 0 | .000 | 0 | 16 | .552 | 129 | 4.4 | 10 | 3 | .300 | 99.6 | .670 |
| Victor Santos | NYY | mr | 31 | 2 | 0 | .000 | 0 | 0 | .000 | 14 | 7.0 | 13 | 5 | .385 | 38.9 | .593 |
| Dennis Sarfate | Sea | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 22.0 | .705 |
| Joe Saunders* | SF | sp | 27 | 21 | 2 | .095 | 0 | 12 | .571 | 101 | 4.8 | 16 | 5 | .313 | 97.5 | .648 |
| Curt Schilling | Mil | sp | 41 | 25 | 2 | .080 | 0 | 19 | .760 | 115 | 4.6 | 13 | 4 | .308 | 97.4 | .677 |
| Jason Schmidt | Phi | sp | 35 | 6 | 0 | .000 | 0 | 1 | .167 | 32 | 5.3 | 13 | 7 | .538 | 124.7 | .588 |
| Scott Schoeneweis* | NYM | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 8 | .308 | 21.5 | .594 |
| Chris Schroder | Tor | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 21.6 | .618 |
| Rudy Seanez | Tor | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 9 | .290 | 22.3 | .594 |
| Bobby Seay* | NYY | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 15.8 | .657 |
| Chris Seddon* | Cin | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 28.7 | .554 |
| Zack Segovia | Tor | sp | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 1 | 0 | .000 | 42.0 | .595 |
| Aaron Sele | NYY | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 27.6 | .607 |
| Jae Seo | LAD | sp | 31 | 3 | 0 | .000 | 0 | 1 | .333 | 10 | 3.3 | 0 | 0 | .000 | 77.3 | .599 |
| Tom Shearn | Flo | sp | 30 | 9 | 0 | .000 | 0 | 6 | .667 | 74 | 8.2 | 6 | 5 | .833 | 92.6 | .612 |
| Ben Sheets | Tex | sp | 29 | 27 | 2 | .074 | 0 | 18 | .667 | 122 | 4.5 | 23 | 10 | .435 | 104.5 | .631 |
| George Sherrill* | Min | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 2 | .087 | 19.5 | .609 |
| James Shields | LAD | sp | 26 | 32 | 4 | .125 | 2 | 22 | .688 | 152 | 4.8 | 11 | 1 | .091 | 104.9 | .671 |
| Scot Shields | SF | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 23.3 | .606 |
| Brian Shouse* | Sea | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 3 | .136 | 12.7 | .642 |
| Carlos Silva | Det | sp | 29 | 32 | 2 | .063 | 0 | 16 | .500 | 140 | 4.4 | 21 | 10 | .476 | 93.7 | .666 |
| Jason Simontacchi | NYM | sp | 34 | 16 | 0 | .000 | 0 | 7 | .438 | 69 | 4.3 | 10 | 5 | .500 | 84.7 | .652 |
| Andrew Sisco* | LAD | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 23.8 | .560 |
| Doug Slaten* | ChW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 3 | .143 | 16.6 | .598 |
| Kevin Slowey | NYY | sp | 24 | 12 | 0 | .000 | 0 | 3 | .250 | 31 | 2.6 | 3 | 3 | 1.000 | 99.4 | .681 |
| Joe Smith | ChW | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 22.6 | .623 |
| John Smoltz | ChW | sp | 41 | 32 | 5 | .156 | 1 | 17 | .531 | 144 | 4.5 | 20 | 5 | .250 | 104.0 | .655 |
| Ian Snell | Was | sp | 26 | 32 | 3 | .094 | 2 | 21 | .656 | 139 | 4.3 | 14 | 1 | .071 | 104.3 | .645 |
| Kyle Snyder | Bos | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 29.5 | .574 |
| Andy Sonnanstine | Bos | sp | 25 | 25 | 0 | .000 | 0 | 15 | .600 | 122 | 4.9 | 14 | 6 | .429 | 86.1 | .659 |
| Joakim Soria | StL | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 18.9 | .652 |
| Rafael Soriano | Atl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 2 | .080 | 18.7 | .679 |
| Jorge Sosa | Tor | mr | 31 | 26 | 1 | .038 | 1 | 11 | .423 | 135 | 5.2 | 30 | 9 | .300 | 91.6 | .605 |
| Jeremy Sowers* | Pit | sp | 25 | 12 | 0 | .000 | 0 | 8 | .667 | 70 | 5.8 | 3 | 0 | .000 | 90.3 | .638 |
| Justin Speier | Phi | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 18.7 | .671 |
| Ryan Speier | Min | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 30.4 | .607 |
| Russ Springer | Hou | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 | 21.3 | .629 |
| Chris Spurling | NYY | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 27.4 | .635 |
| Jason Stanford* | Was | mr | 31 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 1 | 1 | 1.000 | 50.3 | .629 |
| Mike Stanton* | Tor | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 | 30.6 | .640 |
| Tim Stauffer | KC | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 1 | 0 | .000 | 63.5 | .504 |
| Mitch Stetter* | Bos | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 8.5 | .529 |
| Huston Street | Det | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 20.3 | .670 |
| Jeff Suppan | Tex | sp | 33 | 34 | 2 | .059 | 1 | 14 | .412 | 145 | 4.3 | 32 | 13 | .406 | 103.6 | .616 |
| Jon Switzer* | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 9.4 | .702 |
| Brian Tallet* | SF | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 21.4 | .628 |
| Taylor Tankersley* | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 9 | .310 | 21.6 | .581 |
| Jack Taschner* | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 7 | .259 | 22.5 | .559 |
| Jordan Tata | Cle | sp | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 2 | 0 | .000 | 98.0 | .592 |
| Ty Taubenheim | Min | sp | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 10 | 5.0 | 4 | 3 | .750 | 18.5 | .432 |
| Julian Tavarez | Phi | sp | 35 | 27 | 6 | .222 | 0 | 14 | .519 | 126 | 4.7 | 11 | 5 | .455 | 101.9 | .622 |
| Robinson Tejeda | Tex | sp | 26 | 18 | 0 | .000 | 0 | 5 | .278 | 94 | 5.2 | 12 | 3 | .250 | 101.9 | .581 |
| Joe Thatcher* | LAD | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 23.6 | .682 |
| Brad Thompson | LAD | mr | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 25 | 4.2 | 1 | 0 | .000 | 87.0 | .607 |
| John Thomson | Col | sp | 34 | 3 | 1 | .333 | 0 | 0 | .000 | 17 | 5.7 | 3 | 3 | 1.000 | 99.0 | .636 |
| Matt Thornton* | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 6 | .194 | 20.4 | .637 |
| Erick Threets* | SF | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 31.0 | .500 |
| Mike Timlin | Mil | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 16.6 | .651 |
| Brett Tomko | Was | mr | 35 | 9 | 0 | .000 | 0 | 3 | .333 | 51 | 5.7 | 12 | 6 | .500 | 49.7 | .604 |
| Salomon Torres | Bos | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 | 21.8 | .597 |
| Josh Towers | Oak | sp | 31 | 18 | 3 | .167 | 0 | 11 | .611 | 90 | 5.0 | 7 | 3 | .429 | 98.2 | .653 |
| Billy Traber* | Tor | mr | 28 | 6 | 0 | .000 | 0 | 0 | .000 | 7 | 1.2 | 15 | 7 | .467 | 52.1 | .583 |
| Steve Trachsel | Phi | sp | 37 | 32 | 4 | .125 | 1 | 9 | .281 | 191 | 6.0 | 23 | 11 | .478 | 92.4 | .603 |
| Chin-hui Tsao | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 24.0 | .612 |
| Derrick Turnbow | ChC | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 19.9 | .559 |
| Jose Valverde | LAD | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 8 | .471 | 20.6 | .633 |
| John Van Benschoten | Pit | sp | 28 | 5 | 0 | .000 | 0 | 1 | .200 | 23 | 4.6 | 6 | 1 | .167 | 76.0 | .513 |
| Rick VandenHurk | ChW | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 1 | 0 | .000 | 67.0 | .567 |
| Claudio Vargas | Oak | sp | 30 | 28 | 1 | .036 | 0 | 7 | .250 | 144 | 5.1 | 32 | 17 | .531 | 92.4 | .594 |
| Javier Vazquez | Cle | sp | 31 | 32 | 4 | .125 | 1 | 20 | .625 | 190 | 5.9 | 14 | 4 | .286 | 106.1 | .664 |
| Jose Veras | Det | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 24.2 | .541 |
| Justin Verlander | Tor | sp | 25 | 35 | 5 | .143 | 2 | 17 | .486 | 120 | 3.4 | 23 | 7 | .304 | 110.5 | .618 |
| Carlos Villanueva | LAD | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 27.9 | .578 |
| Oscar Villarreal | Oak | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 9 | .290 | 34.9 | .609 |
| Ron Villone* | StL | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 15.6 | .652 |
| Luis Vizcaino | Hou | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 28.5 | .602 |
| Edinson Volquez | Ari | sp | 24 | 9 | 0 | .000 | 0 | 3 | .333 | 47 | 5.2 | 10 | 6 | .600 | 92.8 | .599 |
| Billy Wagner* | ChW | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 20.0 | .630 |
| Adam Wainwright | ChC | sp | 26 | 32 | 3 | .094 | 3 | 26 | .813 | 156 | 4.9 | 27 | 7 | .259 | 103.5 | .626 |
| Tim Wakefield | Det | sp | 41 | 32 | 3 | .094 | 1 | 18 | .563 | 220 | 6.9 | 19 | 11 | .579 | 91.1 | .620 |
| Jamie Walker* | Atl | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 16.7 | .656 |
| Tyler Walker | Pit | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 24.8 | .605 |
| Chien-Ming Wang | SD | sp | 28 | 32 | 5 | .156 | 4 | 25 | .781 | 183 | 5.7 | 16 | 3 | .188 | 92.7 | .638 |
| Jarrod Washburn* | NYM | sp | 33 | 32 | 4 | .125 | 2 | 15 | .469 | 120 | 3.8 | 25 | 10 | .400 | 96.9 | .619 |
| Ehren Wassermann | Col | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 21.7 | .635 |
| David Weathers | Cle | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 | 16.7 | .596 |
| Jeff Weaver | Col | sp | 31 | 31 | 3 | .097 | 0 | 9 | .290 | 142 | 4.6 | 24 | 5 | .208 | 96.1 | .663 |
| Jered Weaver | Cin | sp | 25 | 32 | 1 | .031 | 0 | 15 | .469 | 146 | 4.6 | 20 | 12 | .600 | 96.8 | .643 |
| Brandon Webb | Sea | sp | 29 | 32 | 7 | .219 | 3 | 23 | .719 | 175 | 5.5 | 17 | 5 | .294 | 111.2 | .641 |
| Todd Wellemeyer | Det | mr | 29 | 21 | 0 | .000 | 0 | 4 | .190 | 128 | 6.1 | 27 | 6 | .222 | 83.9 | .589 |
| David Wells* | NYY | sp | 45 | 32 | 0 | .000 | 0 | 11 | .344 | 108 | 3.4 | 25 | 5 | .200 | 89.6 | .641 |
| Kip Wells | Tex | sp | 31 | 30 | 2 | .067 | 0 | 9 | .300 | 162 | 5.4 | 36 | 20 | .556 | 99.6 | .596 |
| Jake Westbrook | Was | sp | 30 | 27 | 3 | .111 | 1 | 15 | .556 | 103 | 3.8 | 20 | 9 | .450 | 95.0 | .629 |
| Dan Wheeler | Cle | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 25.5 | .652 |
| Bob Wickman | Tex | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 19.9 | .598 |
| Todd Williams | Mil | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 23.3 | .622 |
| Woody Williams | KC | sp | 41 | 36 | 2 | .056 | 0 | 19 | .528 | 149 | 4.1 | 30 | 12 | .400 | 95.4 | .626 |
| Scott Williamson | Tam | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 20.3 | .525 |
| Dontrelle Willis* | SF | sp | 26 | 35 | 0 | .000 | 0 | 15 | .429 | 195 | 5.6 | 25 | 6 | .240 | 101.3 | .593 |
| Brian Wilson | Was | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 12.7 | .702 |
| C.J. Wilson* | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 21.2 | .587 |
| Matt Wise | SF | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 28.9 | .617 |
| Randy Wolf* | Bos | sp | 31 | 18 | 0 | .000 | 0 | 8 | .444 | 75 | 4.2 | 15 | 6 | .400 | 91.1 | .629 |
| Brian Wolfe | StL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 20.8 | .637 |
| Kerry Wood | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 23.8 | .596 |
| Jamey Wright | ChC | mr | 33 | 10 | 0 | .000 | 0 | 4 | .400 | 49 | 4.9 | 2 | 1 | .500 | 73.6 | .599 |
| Michael Wuertz | NYY | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 22.4 | .606 |
| Tyler Yates | NYM | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 13 | .351 | 22.7 | .607 |
| Shane Youman* | StL | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 14.5 | .621 |
| Chris Young | Sea | sp | 29 | 31 | 0 | .000 | 0 | 14 | .452 | 202 | 6.5 | 18 | 7 | .389 | 100.8 | .592 |
| Carlos Zambrano | Det | sp | 27 | 35 | 1 | .029 | 0 | 16 | .457 | 231 | 6.6 | 23 | 13 | .565 | 108.4 | .584 |
| Victor Zambrano | Atl | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 16.7 | .700 |
| Barry Zito* | Ari | sp | 30 | 33 | 1 | .030 | 0 | 17 | .515 | 180 | 5.5 | 9 | 6 | .667 | 93.8 | .610 |
| Joel Zumaya | SD | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 16.3 | .662 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | PCH/G | STR% |
| David Aardsma | Min | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 22.0 | .636 |
| Jeremy Accardo | Ari | cl | 26 | 37 | 33 | .892 | 4 | .108 | 1 | 15 | 6 | .400 | 68 | 68 | 59 | 19.8 | .645 |
| Manny Acosta | StL | mr | 27 | 4 | 2 | .500 | 2 | .500 | 2 | 17 | 2 | .118 | 21 | 21 | 12 | 19.8 | .565 |
| Jeremy Affeldt* | Tam | mr | 29 | 5 | 3 | .600 | 2 | .400 | 19 | 61 | 11 | .180 | 73 | 73 | 22 | 22.7 | .578 |
| Jonathan Albaladejo | StL | mr | 25 | 2 | 1 | .500 | 1 | .500 | 3 | 12 | 6 | .500 | 18 | 18 | 8 | 22.8 | .630 |
| Matt Albers | Tam | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 78.1 | .600 |
| Greg Aquino | Cin | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 0 | .000 | 8 | 8 | 4 | 26.8 | .645 |
| Tony Armas | Col | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 101.5 | .608 |
| Bronson Arroyo | Atl | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 40 | 0 | 0 | 92.8 | .647 |
| Jose Ascanio | Ari | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 6 | 6 | 2 | 23.2 | .647 |
| Luis Ayala | LAD | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 3 | 12 | 5 | .417 | 23 | 23 | 8 | 20.5 | .637 |
| Brandon Backe | NYY | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 108.0 | .585 |
| Mike Bacsik* | Atl | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 1 | 0 | 83.0 | .647 |
| Cha Seung Baek | StL | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 103.1 | .660 |
| Danys Baez | Pit | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 1 | 46 | 17 | .370 | 59 | 59 | 19 | 25.5 | .599 |
| Homer Bailey | LAD | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 93.5 | .529 |
| Scott Baker | NYM | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 27 | 4 | 2 | 81.1 | .671 |
| John Bale* | LAD | mr | 34 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 2 | 32.5 | .615 |
| Josh Banks | SF | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 1 | 1 | 0 | 18.0 | .667 |
| Brian Bannister | ChW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 91.0 | .631 |
| Daniel Barone | Ari | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 0 | 19.0 | .711 |
| Miguel Batista | Was | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.8 | .607 |
| Yorman Bazardo | LAA | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 2 | 11 | 0 | .000 | 12 | 12 | 4 | 25.0 | .593 |
| Josh Beckett | Flo | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 101.6 | .673 |
| Erik Bedard* | Tor | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 113.5 | .638 |
| Joe Beimel* | ChC | mr | 31 | 8 | 2 | .250 | 4 | .500 | 19 | 37 | 8 | .216 | 70 | 70 | 22 | 18.4 | .628 |
| Matt Belisle | NYY | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 96.1 | .643 |
| Heath Bell | Ari | mr | 30 | 10 | 3 | .300 | 5 | .500 | 21 | 43 | 17 | .395 | 80 | 80 | 21 | 19.7 | .627 |
| Armando Benitez | Tam | mr | 35 | 0 | 0 | .000 | 0 | .000 | 1 | 12 | 3 | .250 | 11 | 11 | 7 | 24.5 | .615 |
| Jeff Bennett | Oak | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 92.0 | .641 |
| Joaquin Benoit | Oak | mr | 30 | 4 | 1 | .250 | 3 | .750 | 6 | 80 | 31 | .387 | 57 | 57 | 24 | 29.4 | .633 |
| Jason Bergmann | Cin | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 98.5 | .607 |
| Rafael Betancourt | ChW | mr | 33 | 7 | 6 | .857 | 1 | .143 | 18 | 41 | 9 | .220 | 64 | 64 | 23 | 20.3 | .724 |
| Chad Billingsley | Ari | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 34 | 7 | 3 | 90.9 | .601 |
| Kurt Birkins* | LAA | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 18.0 | .583 |
| Travis Blackley* | Cin | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 85.7 | .553 |
| Joe Blanton | NYY | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 101.6 | .671 |
| Jeremy Bonderman | LAD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.5 | .663 |
| Boof Bonser | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 98.1 | .615 |
| Chris Booker | Phi | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 3 | 3 | 0 | 48.7 | .521 |
| Chris Bootcheck | Min | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 2 | 15 | 5 | .333 | 24 | 24 | 12 | 23.5 | .636 |
| Dave Borkowski | Oak | mr | 31 | 2 | 2 | 1.000 | 0 | .000 | 2 | 20 | 6 | .300 | 27 | 27 | 15 | 24.7 | .592 |
| Joe Borowski | Sea | cl | 37 | 3 | 2 | .667 | 0 | .000 | 6 | 46 | 17 | .370 | 54 | 54 | 22 | 23.9 | .670 |
| Micah Bowie* | SD | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 1 | 0 | 81.3 | .605 |
| Blaine Boyer | Oak | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 3 | 3 | 3 | 19.7 | .610 |
| Dallas Braden* | Atl | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 14 | 2 | 2 | 77.6 | .636 |
| Chad Bradford | Ari | mr | 33 | 2 | 0 | .000 | 1 | .500 | 6 | 34 | 17 | .500 | 52 | 52 | 6 | 21.1 | .641 |
| Ryan Braun | NYY | mr | 27 | 0 | 0 | .000 | 0 | .000 | 3 | 15 | 5 | .333 | 24 | 24 | 14 | 37.9 | .594 |
| Chris Britton | Cin | mr | 25 | 2 | 1 | .500 | 1 | .500 | 4 | 9 | 4 | .444 | 15 | 15 | 7 | 20.2 | .597 |
| Lance Broadway | Flo | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 114.0 | .610 |
| Doug Brocail | Was | mr | 41 | 14 | 9 | .643 | 5 | .357 | 13 | 48 | 12 | .250 | 67 | 67 | 27 | 18.5 | .639 |
| Andrew Brown | Tam | mr | 27 | 7 | 4 | .571 | 2 | .286 | 1 | 28 | 9 | .321 | 36 | 36 | 18 | 31.1 | .616 |
| Jonathan Broxton | Flo | mr | 24 | 10 | 6 | .600 | 3 | .300 | 24 | 31 | 5 | .161 | 72 | 72 | 24 | 19.7 | .648 |
| Brian Bruney | Sea | mr | 26 | 3 | 1 | .333 | 2 | .667 | 4 | 31 | 12 | .387 | 42 | 42 | 17 | 23.8 | .571 |
| Clay Buchholz | Det | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 1 | 0 | 94.6 | .590 |
| Taylor Buchholz | Min | mr | 26 | 3 | 2 | .667 | 0 | .000 | 6 | 39 | 11 | .282 | 43 | 34 | 11 | 44.7 | .647 |
| Billy Buckner | Tex | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 102.8 | .595 |
| Mark Buehrle* | LAA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 99.8 | .658 |
| Jason Bulger | ChC | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 0 | 0 | .000 | 7 | 7 | 2 | 34.4 | .581 |
| Bryan Bullington | Pit | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 1 | 60.0 | .614 |
| Ambiorix Burgos | Bos | mr | 24 | 2 | 1 | .500 | 1 | .500 | 2 | 29 | 6 | .207 | 23 | 23 | 7 | 23.8 | .578 |
| A.J. Burnett | Col | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 106.0 | .632 |
| Brian Burres* | Was | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 20 | 9 | .450 | 37 | 21 | 10 | 60.8 | .583 |
| Jared Burton | Bos | mr | 27 | 7 | 2 | .286 | 4 | .571 | 4 | 54 | 23 | .426 | 52 | 52 | 9 | 28.4 | .590 |
| Dave Bush | KC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 93.7 | .623 |
| Paul Byrd | Pit | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 1 | 0 | 85.6 | .682 |
| Tim Byrdak* | Col | mr | 34 | 5 | 0 | .000 | 5 | 1.000 | 4 | 36 | 13 | .361 | 45 | 45 | 3 | 27.3 | .617 |
| Daniel Cabrera | Mil | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 35 | 2 | 1 | 100.4 | .606 |
| Fernando Cabrera | StL | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 4 | 4 | 1 | 18.0 | .556 |
| Matt Cain | SF | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 107.3 | .606 |
| Kiko Calero | ChW | mr | 33 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 8 | 8 | 2 | 27.6 | .584 |
| Kevin Cameron | Det | mr | 28 | 5 | 2 | .400 | 1 | .200 | 6 | 40 | 23 | .575 | 47 | 47 | 14 | 36.4 | .578 |
| Shawn Camp | Hou | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 21 | 6 | .286 | 42 | 42 | 19 | 25.5 | .638 |
| Jose Capellan | Hou | mr | 27 | 3 | 3 | 1.000 | 0 | .000 | 0 | 17 | 0 | .000 | 22 | 22 | 15 | 21.4 | .631 |
| Matt Capps | Was | mr | 24 | 39 | 33 | .846 | 6 | .154 | 0 | 23 | 6 | .261 | 51 | 51 | 42 | 16.5 | .677 |
| Chris Capuano* | NYY | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 104.7 | .618 |
| Buddy Carlyle | Atl | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 91.3 | .628 |
| Fausto Carmona | SD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 1 | 1 | 95.4 | .631 |
| Chris Carpenter | Min | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 72.0 | .618 |
| Marcos Carvajal | Oak | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 1 | 9.0 | .556 |
| Santiago Casilla | Col | mr | 27 | 4 | 1 | .250 | 3 | .750 | 3 | 23 | 7 | .304 | 42 | 42 | 11 | 26.7 | .605 |
| Jack Cassel | Tex | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 1 | 0 | 78.7 | .606 |
| Fabio Castro* | ChW | mr | 23 | 2 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 10 | 10 | 1 | 10.4 | .423 |
| Gustavo Chacin* | LAD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 71.7 | .671 |
| Shawn Chacon | Cin | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 2 | 44 | 15 | .341 | 67 | 67 | 19 | 26.8 | .583 |
| Joba Chamberlain | Oak | mr | 22 | 6 | 5 | .833 | 1 | .167 | 3 | 18 | 6 | .333 | 21 | 21 | 14 | 25.6 | .607 |
| Rocky Cherry | Was | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 6 | 6 | 3 | .500 | 18 | 18 | 7 | 18.7 | .604 |
| Matt Chico* | Det | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 82.2 | .598 |
| Vinnie Chulk | KC | mr | 29 | 8 | 1 | .125 | 7 | .875 | 11 | 55 | 20 | .364 | 76 | 76 | 26 | 22.8 | .628 |
| Roger Clemens | SD | sp | 45 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 96.6 | .637 |
| Tyler Clippard | Ari | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 85.3 | .586 |
| Todd Coffey | SF | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 2 | 30 | 13 | .433 | 31 | 31 | 12 | 23.6 | .615 |
| Jesus Colome | Pit | mr | 30 | 5 | 2 | .400 | 3 | .600 | 6 | 62 | 26 | .419 | 71 | 70 | 10 | 26.0 | .618 |
| Bartolo Colon | Tor | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.1 | .636 |
| Jose Contreras | Bal | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 96.3 | .618 |
| Aaron Cook | Atl | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 31 | 1 | 1 | 103.2 | .632 |
| Chad Cordero | SF | cl | 26 | 21 | 14 | .667 | 7 | .333 | 2 | 20 | 8 | .400 | 52 | 52 | 34 | 22.6 | .619 |
| Francisco Cordero | Oak | cl | 33 | 30 | 25 | .833 | 5 | .167 | 0 | 27 | 8 | .296 | 54 | 54 | 43 | 19.9 | .619 |
| Bryan Corey | Tam | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 3 | .273 | 7 | 7 | 1 | 32.9 | .565 |
| Lance Cormier | Flo | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 76.5 | .595 |
| Manny Corpas | Sea | mr | 25 | 32 | 31 | .969 | 1 | .031 | 1 | 37 | 6 | .162 | 62 | 62 | 55 | 16.4 | .677 |
| Kevin Correia | LAA | mr | 27 | 2 | 1 | .500 | 1 | .500 | 2 | 32 | 9 | .281 | 41 | 41 | 22 | 23.1 | .624 |
| Neal Cotts* | Tam | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 13 | 1 | .077 | 20 | 20 | 8 | 25.4 | .578 |
| Jon Coutlangus* | Det | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 7 | 43 | 21 | .488 | 51 | 51 | 18 | 21.0 | .564 |
| Juan Cruz | Det | mr | 29 | 8 | 5 | .625 | 2 | .250 | 19 | 65 | 22 | .338 | 58 | 58 | 15 | 25.5 | .594 |
| John Danks* | Col | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 97.4 | .625 |
| Kyle Davies | Cin | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 1 | 1 | 85.9 | .601 |
| Doug Davis* | StL | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 102.1 | .598 |
| Jorge De La Rosa* | Bos | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 28 | 1 | 0 | 67.6 | .632 |
| Manny Delcarmen | Cle | mr | 26 | 9 | 3 | .333 | 5 | .556 | 12 | 38 | 13 | .342 | 47 | 47 | 19 | 24.1 | .615 |
| Ryan Dempster | Min | cl | 31 | 13 | 9 | .692 | 4 | .308 | 21 | 54 | 14 | .259 | 65 | 65 | 26 | 20.1 | .597 |
| Julio DePaula | NYY | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 1 | .100 | 11 | 11 | 6 | 32.0 | .631 |
| Matt DeSalvo | Phi | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 96.4 | .566 |
| Ross Detwiler* | Tex | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 27.0 | .667 |
| Joey Devine | Hou | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 2 | 8 | 3 | .375 | 13 | 13 | 2 | 22.0 | .507 |
| Lenny DiNardo* | Tam | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 91.3 | .603 |
| Scott Dohmann | KC | mr | 30 | 4 | 2 | .500 | 2 | .500 | 3 | 27 | 10 | .370 | 42 | 42 | 27 | 25.4 | .588 |
| Brendan Donnelly | Tor | mr | 36 | 7 | 2 | .286 | 3 | .429 | 1 | 41 | 14 | .341 | 37 | 37 | 17 | 25.7 | .618 |
| Octavio Dotel | Ari | cl | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 4 | 4 | 1 | 18.8 | .693 |
| Scott Downs* | LAA | mr | 32 | 6 | 3 | .500 | 3 | .500 | 14 | 30 | 10 | .333 | 53 | 53 | 20 | 19.1 | .610 |
| Brandon Duckworth | Was | mr | 32 | 1 | 1 | 1.000 | 0 | .000 | 2 | 26 | 6 | .231 | 26 | 24 | 9 | 31.8 | .590 |
| Zach Duke* | Oak | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 1 | 0 | 90.0 | .625 |
| Phil Dumatrait* | NYM | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 66.0 | .510 |
| Chad Durbin | Bos | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 28 | 1 | 1 | 90.1 | .611 |
| J.D. Durbin | SF | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 0 | 79.9 | .562 |
| Adam Eaton | Bal | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 23 | 1 | 0 | 84.0 | .565 |
| Scott Elarton | Mil | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 10 | 2 | 1 | 60.9 | .567 |
| Alan Embree* | Bos | cl | 38 | 8 | 3 | .375 | 3 | .375 | 11 | 61 | 10 | .164 | 78 | 78 | 25 | 17.7 | .672 |
| Kelvim Escobar | Bal | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 103.9 | .621 |
| Dana Eveland* | KC | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 70.5 | .539 |
| Scott Eyre* | Was | mr | 36 | 2 | 1 | .500 | 0 | .000 | 6 | 25 | 9 | .360 | 39 | 39 | 11 | 20.8 | .547 |
| Kyle Farnsworth | Cle | mr | 32 | 2 | 2 | 1.000 | 0 | .000 | 5 | 54 | 18 | .333 | 54 | 54 | 21 | 24.3 | .629 |
| Scott Feldman | Tex | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 25 | 11 | .440 | 37 | 37 | 18 | 33.2 | .536 |
| Pedro Feliciano* | Oak | mr | 31 | 7 | 1 | .143 | 5 | .714 | 13 | 39 | 12 | .308 | 61 | 61 | 22 | 25.6 | .602 |
| Randy Flores* | Ari | mr | 32 | 2 | 1 | .500 | 0 | .000 | 2 | 33 | 9 | .273 | 32 | 32 | 12 | 16.8 | .654 |
| Ron Flores* | NYY | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 26.0 | .731 |
| Gavin Floyd | LAA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 84.3 | .629 |
| Josh Fogg | Ari | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 79.4 | .623 |
| Casey Fossum* | Pit | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 70.8 | .653 |
| Jeff Francis* | LAD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 98.9 | .632 |
| Frank Francisco | Min | mr | 28 | 5 | 1 | .200 | 1 | .200 | 3 | 41 | 13 | .317 | 45 | 45 | 20 | 19.6 | .571 |
| Ryan Franklin | ChC | mr | 35 | 13 | 8 | .615 | 3 | .231 | 16 | 22 | 5 | .227 | 56 | 56 | 16 | 18.4 | .669 |
| Jason Frasor | StL | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 11 | 22 | 7 | .318 | 52 | 52 | 16 | 20.8 | .650 |
| Brian Fuentes* | Tor | cl | 32 | 35 | 27 | .771 | 8 | .229 | 3 | 45 | 14 | .311 | 50 | 50 | 43 | 22.7 | .590 |
| Aaron Fultz* | Tex | mr | 34 | 12 | 4 | .333 | 6 | .500 | 9 | 55 | 18 | .327 | 54 | 54 | 18 | 25.1 | .595 |
| Kason Gabbard* | LAD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 95.8 | .596 |
| Eric Gagne | NYM | cl | 32 | 21 | 15 | .714 | 6 | .286 | 2 | 33 | 10 | .303 | 62 | 62 | 47 | 20.0 | .624 |
| Armando Galarraga | KC | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 89.2 | .553 |
| Sean Gallagher | Tex | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 1 | 40.0 | .488 |
| Yovani Gallardo | StL | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 108.4 | .623 |
| Freddy Garcia | Det | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 82.0 | .634 |
| Harvey Garcia | SF | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 2 | 2 | 1 | 10.0 | .700 |
| Lee Gardner | Bos | mr | 33 | 12 | 7 | .583 | 5 | .417 | 20 | 53 | 18 | .340 | 69 | 69 | 25 | 20.7 | .660 |
| Jon Garland | Pit | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 94.1 | .644 |
| Matt Garza | Oak | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 102.7 | .627 |
| Chad Gaudin | NYM | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 94.9 | .595 |
| Geoff Geary | Flo | mr | 31 | 2 | 1 | .500 | 1 | .500 | 5 | 49 | 19 | .388 | 58 | 58 | 15 | 28.6 | .619 |
| Justin Germano | StL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 94.0 | .627 |
| Tom Glavine* | ChC | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 1 | 1 | 86.8 | .623 |
| Gary Glover | Mil | mr | 31 | 4 | 2 | .500 | 1 | .250 | 2 | 58 | 22 | .379 | 65 | 65 | 22 | 22.7 | .632 |
| Jimmy Gobble* | Flo | mr | 26 | 3 | 1 | .333 | 2 | .667 | 9 | 19 | 4 | .211 | 34 | 34 | 11 | 20.0 | .620 |
| Edgar Gonzalez | Col | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 101.9 | .634 |
| Mike Gonzalez* | Atl | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 9 | 9 | 5 | 24.6 | .561 |
| Tom Gordon | Phi | mr | 40 | 2 | 1 | .500 | 1 | .500 | 0 | 45 | 19 | .422 | 47 | 47 | 16 | 28.0 | .594 |
| Tom Gorzelanny* | Pit | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.2 | .614 |
| John Grabow* | Bal | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 2 | 56 | 22 | .393 | 60 | 60 | 12 | 27.0 | .604 |
| Sean Green | Min | mr | 29 | 5 | 2 | .400 | 2 | .400 | 5 | 33 | 10 | .303 | 39 | 39 | 15 | 20.0 | .601 |
| Kevin Gregg | Det | cl | 30 | 18 | 14 | .778 | 4 | .222 | 14 | 86 | 22 | .256 | 72 | 72 | 36 | 24.6 | .584 |
| Zack Greinke | LAA | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 96.5 | .649 |
| Jason Grilli | Phi | mr | 31 | 10 | 3 | .300 | 5 | .500 | 10 | 36 | 11 | .306 | 56 | 56 | 13 | 22.0 | .617 |
| Eddie Guardado* | Mil | mr | 37 | 3 | 2 | .667 | 1 | .333 | 0 | 18 | 9 | .500 | 18 | 18 | 9 | 20.8 | .602 |
| Matt Guerrier | Sea | mr | 29 | 9 | 5 | .556 | 4 | .444 | 17 | 35 | 14 | .400 | 53 | 53 | 19 | 21.8 | .653 |
| Jeremy Guthrie | Min | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 2 | .286 | 34 | 5 | 0 | 94.9 | .641 |
| Juan Gutierrez | SD | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 70.3 | .701 |
| Roy Halladay | Hou | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 105.4 | .673 |
| Cole Hamels* | Flo | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 97.7 | .656 |
| Jason Hammel | Sea | sp | 25 | 1 | 0 | .000 | 0 | .000 | 1 | 9 | 5 | .556 | 13 | 12 | 8 | 28.9 | .644 |
| Justin Hampson* | SD | mr | 28 | 0 | 0 | .000 | 0 | .000 | 9 | 21 | 6 | .286 | 43 | 43 | 12 | 18.7 | .649 |
| Joel Hanrahan | NYM | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 1 | 1 | 55.8 | .556 |
| Aaron Harang | Cle | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 111.2 | .646 |
| Rich Harden | Col | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 99.3 | .657 |
| Dan Haren | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 103.7 | .657 |
| Kevin Hart | LAA | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 5 | 1 | .200 | 8 | 8 | 4 | 28.9 | .589 |
| LaTroy Hawkins | Tex | mr | 35 | 16 | 11 | .688 | 3 | .188 | 7 | 51 | 18 | .353 | 50 | 50 | 27 | 20.8 | .631 |
| Aaron Heilman | Hou | mr | 29 | 7 | 4 | .571 | 3 | .429 | 14 | 55 | 23 | .418 | 72 | 72 | 23 | 23.4 | .651 |
| Mark Hendrickson* | Sea | mr | 34 | 2 | 2 | 1.000 | 0 | .000 | 2 | 19 | 2 | .105 | 41 | 23 | 10 | 55.7 | .645 |
| Sean Henn* | Flo | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 1 | 16.0 | .625 |
| Brad Hennessey | Flo | cl | 28 | 5 | 1 | .200 | 4 | .800 | 7 | 27 | 10 | .370 | 45 | 45 | 14 | 26.0 | .602 |
| Clay Hensley | Ari | sp | 28 | 2 | 0 | .000 | 1 | .500 | 0 | 10 | 5 | .500 | 8 | 8 | 1 | 32.5 | .581 |
| Matt Herges | Pit | mr | 38 | 4 | 2 | .500 | 1 | .250 | 4 | 11 | 4 | .364 | 34 | 34 | 11 | 20.1 | .645 |
| Felix Hernandez | Bal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 101.5 | .644 |
| Livan Hernandez | Atl | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 38 | 0 | 0 | 90.6 | .586 |
| Orlando Hernandez | ChC | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 28 | 2 | 0 | 95.9 | .597 |
| Roberto Hernandez | Atl | mr | 43 | 3 | 2 | .667 | 1 | .333 | 2 | 26 | 12 | .462 | 43 | 43 | 16 | 22.6 | .618 |
| Rich Hill* | ChC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 99.4 | .608 |
| Shawn Hill | Tam | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 101.8 | .632 |
| Jason Hirsh | Ari | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 92.0 | .612 |
| Luke Hochevar | Mil | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 3 | 2 | 1 | 47.7 | .594 |
| Jim Hoey | NYM | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 18 | 8 | .444 | 15 | 15 | 5 | 22.9 | .523 |
| Trevor Hoffman | SD | cl | 40 | 3 | 0 | .000 | 3 | 1.000 | 5 | 20 | 1 | .050 | 52 | 52 | 26 | 20.1 | .663 |
| D.J. Houlton | Flo | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 3 | .600 | 8 | 8 | 4 | 31.0 | .661 |
| J.P. Howell* | Flo | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 76.3 | .623 |
| Bob Howry | ChC | mr | 34 | 3 | 1 | .333 | 2 | .667 | 16 | 25 | 12 | .480 | 61 | 61 | 23 | 24.4 | .643 |
| Tim Hudson | Min | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 103.4 | .644 |
| Phil Hughes | SF | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 101.2 | .611 |
| Philip Humber | LAA | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 1 | 1 | 0 | 16.0 | .563 |
| Kei Igawa* | KC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 90.3 | .582 |
| Jason Isringhausen | LAA | cl | 35 | 19 | 13 | .684 | 5 | .263 | 0 | 30 | 7 | .233 | 37 | 37 | 36 | 18.6 | .607 |
| Edwin Jackson | Hou | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 87.3 | .604 |
| Chuck James* | ChW | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 85.1 | .603 |
| Casey Janssen | LAA | mr | 26 | 8 | 3 | .375 | 4 | .500 | 7 | 27 | 8 | .296 | 45 | 45 | 18 | 22.8 | .620 |
| Bobby Jenks | Pit | cl | 27 | 37 | 30 | .811 | 7 | .189 | 0 | 34 | 7 | .206 | 66 | 66 | 50 | 18.5 | .696 |
| Jason Jennings | Cle | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 89.9 | .625 |
| Ubaldo Jimenez | NYY | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 100.5 | .601 |
| Josh Johnson | NYY | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 65.0 | .560 |
| Randy Johnson* | NYM | sp | 44 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 98.5 | .648 |
| Tyler Johnson* | Cle | mr | 27 | 6 | 4 | .667 | 2 | .333 | 10 | 30 | 9 | .300 | 36 | 36 | 13 | 18.6 | .625 |
| Todd Jones | ChC | cl | 40 | 5 | 4 | .800 | 1 | .200 | 7 | 47 | 19 | .404 | 60 | 60 | 21 | 24.3 | .635 |
| Jorge Julio | Phi | mr | 29 | 3 | 1 | .333 | 2 | .667 | 2 | 42 | 21 | .500 | 47 | 47 | 18 | 31.3 | .595 |
| Jair Jurrjens | Mil | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 2 | 1 | 67.9 | .638 |
| Jeff Karstens | Cin | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 1 | 0 | 53.0 | .506 |
| Scott Kazmir* | SF | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 103.2 | .614 |
| Kyle Kendrick | LAD | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 87.1 | .647 |
| Ian Kennedy | Phi | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 111.8 | .611 |
| Joe Kennedy* | Phi | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 89.2 | .602 |
| Logan Kensing | Mil | mr | 25 | 1 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 9 | 9 | 6 | 20.8 | .626 |
| Byung-Hyun Kim | Tam | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 63.8 | .568 |
| Ray King* | KC | mr | 34 | 5 | 1 | .200 | 3 | .600 | 11 | 57 | 19 | .333 | 68 | 68 | 16 | 21.3 | .545 |
| Steve Kline* | StL | mr | 35 | 3 | 3 | 1.000 | 0 | .000 | 2 | 25 | 7 | .280 | 40 | 40 | 24 | 21.1 | .621 |
| Mike Koplove | Col | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 4 | 4 | 1 | 12.3 | .531 |
| Hong-Chih Kuo* | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 4 | 3 | 1 | 31.8 | .567 |
| John Lackey | Hou | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 107.2 | .654 |
| Aaron Laffey* | ChW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 90.6 | .655 |
| John Lannan* | Mil | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 97.7 | .558 |
| Brian Lawrence | Phi | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 98.5 | .570 |
| Cliff Lee* | Cle | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 86.3 | .602 |
| Jon Lester* | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 91.4 | .596 |
| Jensen Lewis | Min | mr | 24 | 17 | 14 | .824 | 3 | .176 | 3 | 27 | 6 | .222 | 31 | 31 | 21 | 21.3 | .611 |
| Brad Lidge | Atl | cl | 31 | 39 | 32 | .821 | 7 | .179 | 1 | 38 | 9 | .237 | 79 | 79 | 66 | 20.3 | .632 |
| Jon Lieber | Phi | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 97.2 | .641 |
| Ted Lilly* | Hou | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 98.8 | .647 |
| Tim Lincecum | Tor | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 99.3 | .613 |
| Matt Lindstrom | Bos | mr | 28 | 28 | 20 | .714 | 8 | .286 | 9 | 49 | 18 | .367 | 72 | 72 | 45 | 23.1 | .614 |
| Scott Linebrink | Mil | mr | 31 | 4 | 3 | .750 | 1 | .250 | 5 | 34 | 5 | .147 | 66 | 66 | 23 | 20.4 | .628 |
| Jesse Litsch | Cin | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 96.3 | .631 |
| Wes Littleton | Cin | mr | 25 | 5 | 4 | .800 | 1 | .200 | 1 | 27 | 9 | .333 | 46 | 46 | 29 | 19.0 | .619 |
| Bobby Livingston* | Col | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 89.1 | .687 |
| Radhames Liz | Bal | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 1 | .333 | 12 | 6 | 3 | 64.2 | .509 |
| Esteban Loaiza | Flo | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 71.5 | .549 |
| Kameron Loe | Bos | sp | 26 | 2 | 2 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 33 | 5 | 3 | 77.2 | .616 |
| Adam Loewen* | LAA | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 101.7 | .554 |
| Boone Logan* | Cle | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 1 | 15 | 6 | .400 | 10 | 10 | 4 | 24.1 | .585 |
| Kyle Lohse | Bal | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 100.3 | .608 |
| Braden Looper | Cle | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 102.1 | .640 |
| Aquilino Lopez | Sea | mr | 33 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 2 | 2 | 1 | 8.5 | .824 |
| Javier Lopez* | Col | mr | 30 | 5 | 2 | .400 | 3 | .600 | 8 | 31 | 8 | .258 | 51 | 51 | 22 | 19.7 | .592 |
| Rodrigo Lopez | StL | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 100.2 | .649 |
| Derek Lowe | ChW | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 104.2 | .622 |
| Mark Lowe | StL | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 3 | 3 | 1 | 25.3 | .526 |
| Noah Lowry* | Mil | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 99.4 | .575 |
| Ruddy Lugo | KC | mr | 28 | 3 | 1 | .333 | 2 | .667 | 0 | 49 | 18 | .367 | 54 | 54 | 23 | 33.4 | .586 |
| Brandon Lyon | Tam | mr | 28 | 8 | 3 | .375 | 5 | .625 | 20 | 60 | 19 | .317 | 72 | 72 | 22 | 21.8 | .613 |
| Mike MacDougal | Bal | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 13 | 7 | .538 | 22 | 22 | 10 | 23.6 | .575 |
| Greg Maddux | ChC | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 88.6 | .679 |
| Ryan Madson | NYM | mr | 27 | 0 | 0 | .000 | 0 | .000 | 3 | 47 | 10 | .213 | 52 | 52 | 16 | 27.0 | .635 |
| Ron Mahay* | Det | mr | 37 | 9 | 4 | .444 | 2 | .222 | 22 | 53 | 13 | .245 | 62 | 62 | 14 | 21.2 | .563 |
| Paul Maholm* | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 92.6 | .636 |
| John Maine | Oak | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 34 | 1 | 0 | 96.3 | .617 |
| Gary Majewski | Tex | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 4 | .667 | 7 | 7 | 3 | 29.7 | .678 |
| Shaun Marcum | Tam | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 100.4 | .640 |
| Carlos Marmol | Tam | mr | 25 | 39 | 34 | .872 | 5 | .128 | 1 | 54 | 17 | .315 | 59 | 59 | 51 | 23.4 | .584 |
| Jason Marquis | StL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 102.7 | .607 |
| Jay Marshall* | Det | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 13 | 2 | .154 | 15 | 15 | 7 | 22.3 | .569 |
| Sean Marshall* | Flo | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 95.0 | .625 |
| Damaso Marte* | Ari | mr | 33 | 10 | 5 | .500 | 3 | .300 | 11 | 23 | 7 | .304 | 64 | 64 | 18 | 17.6 | .605 |
| Tom Martin* | Atl | mr | 38 | 3 | 2 | .667 | 1 | .333 | 1 | 40 | 20 | .500 | 65 | 65 | 13 | 25.0 | .600 |
| Carlos Martinez | Cin | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 3 | .750 | 4 | 4 | 2 | 19.0 | .553 |
| Pedro Martinez | Bos | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 95.5 | .639 |
| Nick Masset | Oak | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 77.5 | .555 |
| Tom Mastny | KC | mr | 27 | 2 | 2 | 1.000 | 0 | .000 | 4 | 56 | 22 | .393 | 64 | 64 | 20 | 34.5 | .604 |
| Julio Mateo | Cin | mr | 30 | 3 | 2 | .667 | 1 | .333 | 0 | 3 | 1 | .333 | 7 | 7 | 5 | 24.0 | .625 |
| Daisuke Matsuzaka | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 113.4 | .611 |
| Marcus McBeth | Bos | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 1 | 15.5 | .516 |
| Macay McBride* | Ari | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 6 | 17 | 4 | .235 | 26 | 26 | 8 | 15.1 | .578 |
| Brandon McCarthy | Ari | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 93.4 | .614 |
| Seth McClung | Mil | mr | 27 | 2 | 1 | .500 | 1 | .500 | 0 | 3 | 1 | .333 | 11 | 11 | 6 | 28.1 | .553 |
| Dustin McGowan | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 104.7 | .619 |
| Marty McLeary | NYM | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 0 | 18.0 | .611 |
| Mark McLemore* | NYY | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 14 | 6 | .429 | 12 | 12 | 4 | 31.8 | .580 |
| Gil Meche | Sea | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 100.8 | .645 |
| Brandon Medders | NYY | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 12 | 3 | .250 | 17 | 17 | 8 | 23.4 | .615 |
| Luis Mendoza | Mil | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 3 | 1 | .333 | 6 | 6 | 2 | 28.3 | .665 |
| Cla Meredith | Col | mr | 25 | 5 | 2 | .400 | 3 | .600 | 17 | 47 | 21 | .447 | 75 | 75 | 26 | 18.9 | .674 |
| Jose Mesa | NYM | mr | 42 | 1 | 0 | .000 | 1 | 1.000 | 1 | 17 | 7 | .412 | 24 | 24 | 9 | 25.0 | .568 |
| Randy Messenger | Phi | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 4 | 37 | 15 | .405 | 54 | 54 | 23 | 25.3 | .635 |
| Dan Meyer* | Oak | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 0 | 86.4 | .557 |
| Andrew Miller* | Mil | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 87.7 | .557 |
| Justin Miller | LAD | mr | 30 | 4 | 2 | .500 | 2 | .500 | 3 | 24 | 18 | .750 | 41 | 41 | 20 | 24.8 | .615 |
| Trever Miller* | Phi | mr | 35 | 3 | 2 | .667 | 1 | .333 | 2 | 24 | 13 | .542 | 23 | 23 | 16 | 30.0 | .569 |
| Kevin Millwood | StL | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 102.7 | .647 |
| Zach Miner | Pit | mr | 26 | 2 | 1 | .500 | 0 | .000 | 0 | 20 | 7 | .350 | 29 | 27 | 11 | 30.4 | .624 |
| Patrick Misch* | NYM | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 5 | .833 | 8 | 7 | 4 | 28.0 | .629 |
| Sergio Mitre | Cin | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 87.0 | .625 |
| Brian Moehler | Tor | mr | 36 | 4 | 4 | 1.000 | 0 | .000 | 1 | 67 | 20 | .299 | 60 | 60 | 27 | 32.8 | .646 |
| Franklin Morales* | Flo | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 92.2 | .619 |
| Juan Morillo | Bos | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 1 | 1 | 1 | 2.0 | 1.000 |
| Matt Morris | Oak | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 102.5 | .630 |
| Brandon Morrow | LAA | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 4 | 4 | 2 | 18.3 | .562 |
| Dustin Moseley | Was | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 4 | 14 | 7 | .500 | 37 | 30 | 18 | 39.1 | .634 |
| Guillermo Mota | Bal | mr | 34 | 2 | 0 | .000 | 0 | .000 | 3 | 38 | 11 | .289 | 44 | 44 | 16 | 27.5 | .615 |
| Jamie Moyer* | Phi | sp | 45 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 104.2 | .643 |
| Peter Moylan | Cin | mr | 29 | 26 | 19 | .731 | 7 | .269 | 5 | 39 | 7 | .179 | 79 | 79 | 53 | 21.2 | .643 |
| Arnie Munoz* | Phi | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 4 | .400 | 8 | 8 | 3 | 36.4 | .495 |
| A.J. Murray* | Det | mr | 26 | 1 | 0 | .000 | 0 | .000 | 1 | 16 | 10 | .625 | 15 | 12 | 4 | 31.4 | .565 |
| Mike Mussina | SD | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 81.9 | .647 |
| Brett Myers | LAA | cl | 27 | 13 | 12 | .923 | 1 | .077 | 6 | 45 | 15 | .333 | 58 | 58 | 28 | 24.6 | .588 |
| Mike Myers* | Tex | mr | 39 | 0 | 0 | .000 | 0 | .000 | 8 | 56 | 24 | .429 | 46 | 46 | 15 | 24.0 | .607 |
| Joe Nathan | ChW | cl | 33 | 33 | 30 | .909 | 3 | .091 | 2 | 28 | 8 | .286 | 67 | 67 | 56 | 14.4 | .686 |
| Pat Neshek | Ari | mr | 27 | 9 | 3 | .333 | 3 | .333 | 12 | 48 | 15 | .313 | 70 | 70 | 28 | 19.5 | .619 |
| Dustin Nippert | ChW | mr | 27 | 2 | 1 | .500 | 1 | .500 | 0 | 7 | 2 | .286 | 12 | 12 | 5 | 43.9 | .617 |
| Ricky Nolasco | Cin | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 101.8 | .624 |
| Leo Nunez | NYM | mr | 24 | 2 | 1 | .500 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 4 | 3 | 59.2 | .664 |
| Eric O'Flaherty* | NYM | mr | 23 | 5 | 1 | .200 | 4 | .800 | 7 | 29 | 10 | .345 | 63 | 63 | 27 | 22.5 | .612 |
| Tomo Ohka | Mil | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 1 | 1 | 89.4 | .630 |
| Ross Ohlendorf | NYM | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 3 | .500 | 4 | 4 | 0 | 16.3 | .585 |
| Will Ohman* | StL | mr | 30 | 3 | 2 | .667 | 1 | .333 | 8 | 27 | 9 | .333 | 42 | 42 | 20 | 16.0 | .622 |
| Hideki Okajima* | SD | mr | 32 | 3 | 2 | .667 | 0 | .000 | 19 | 39 | 8 | .205 | 63 | 63 | 18 | 19.3 | .636 |
| Darren Oliver* | Cle | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 5 | 30 | 12 | .400 | 37 | 37 | 15 | 22.8 | .597 |
| Scott Olsen* | Hou | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 79.3 | .612 |
| Garrett Olson* | Was | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 68.3 | .535 |
| Ramon Ortiz | Pit | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 1 | 1 | 81.6 | .673 |
| Russ Ortiz | StL | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 1 | 0 | 60.0 | .600 |
| Chad Orvella | Col | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 19.0 | .526 |
| Franquelis Osoria | Tex | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 11 | 3 | .273 | 8 | 8 | 3 | 27.6 | .606 |
| Roy Oswalt | Ari | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 98.4 | .628 |
| Akinori Otsuka | Tex | mr | 36 | 14 | 11 | .786 | 2 | .143 | 1 | 27 | 8 | .296 | 32 | 32 | 22 | 19.1 | .638 |
| Henry Owens | NYY | mr | 29 | 2 | 1 | .500 | 1 | .500 | 5 | 17 | 4 | .235 | 18 | 18 | 8 | 19.1 | .624 |
| Micah Owings | LAA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 97.9 | .613 |
| Vicente Padilla | Flo | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 91.9 | .620 |
| Jonathan Papelbon | LAD | cl | 27 | 36 | 32 | .889 | 3 | .083 | 0 | 26 | 6 | .231 | 59 | 59 | 49 | 18.8 | .645 |
| Manny Parra* | Hou | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 91.0 | .604 |
| John Parrish* | Min | mr | 30 | 1 | 0 | .000 | 0 | .000 | 6 | 25 | 8 | .320 | 37 | 37 | 6 | 14.3 | .547 |
| Troy Patton* | Cle | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 97.0 | .608 |
| Felipe Paulino | Mil | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 77.3 | .621 |
| Carl Pavano | NYY | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 95.7 | .610 |
| Jake Peavy | SD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 108.8 | .638 |
| Mike Pelfrey | NYM | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 16 | 1 | 1 | 76.2 | .567 |
| Tony Pena | SF | mr | 26 | 23 | 17 | .739 | 6 | .261 | 4 | 54 | 12 | .222 | 70 | 70 | 35 | 23.1 | .612 |
| Brad Penny | Tam | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 97.3 | .612 |
| Joel Peralta | Tam | mr | 32 | 3 | 0 | .000 | 2 | .667 | 5 | 55 | 16 | .291 | 57 | 57 | 26 | 30.7 | .679 |
| Troy Percival | SD | mr | 38 | 5 | 3 | .600 | 2 | .400 | 10 | 11 | 6 | .545 | 38 | 36 | 9 | 27.9 | .618 |
| Odalis Perez* | Cin | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 91.8 | .623 |
| Oliver Perez* | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.7 | .588 |
| Rafael Perez* | NYY | mr | 26 | 29 | 25 | .862 | 4 | .138 | 1 | 8 | 1 | .125 | 43 | 43 | 36 | 21.1 | .687 |
| Glen Perkins* | Pit | mr | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 1 | .091 | 17 | 17 | 7 | 24.4 | .598 |
| Yusmeiro Petit | Tam | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 79.2 | .640 |
| Billy Petrick | Min | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 2 | 2 | 1 | 8.0 | .500 |
| Andy Pettitte* | Tex | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 107.3 | .620 |
| Joel Pineiro | Bal | mr | 29 | 3 | 2 | .667 | 0 | .000 | 2 | 31 | 11 | .355 | 44 | 37 | 22 | 32.4 | .626 |
| Renyel Pinto* | Bos | mr | 25 | 5 | 0 | .000 | 2 | .400 | 8 | 38 | 11 | .289 | 55 | 55 | 16 | 23.8 | .548 |
| Sidney Ponson | Flo | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 51.5 | .660 |
| Scott Proctor | LAA | mr | 31 | 4 | 2 | .500 | 2 | .500 | 1 | 15 | 9 | .600 | 31 | 31 | 16 | 24.0 | .589 |
| J.J. Putz | SD | cl | 31 | 55 | 54 | .982 | 1 | .018 | 0 | 27 | 4 | .148 | 72 | 72 | 63 | 14.4 | .669 |
| Chad Qualls | LAD | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 4 | 25 | 11 | .440 | 52 | 52 | 18 | 23.4 | .639 |
| Edwar Ramirez | NYY | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 12 | 5 | .417 | 9 | 9 | 3 | 23.1 | .611 |
| Elizardo Ramirez | Phi | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 106.8 | .597 |
| Horacio Ramirez* | KC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 77.9 | .595 |
| Ramon Ramirez | Col | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 1 | 9 | 4 | .444 | 19 | 19 | 11 | 21.8 | .635 |
| Darrell Rasner | Tex | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 91.1 | .603 |
| Jon Rauch | ChW | mr | 29 | 3 | 1 | .333 | 1 | .333 | 5 | 40 | 12 | .300 | 56 | 56 | 19 | 23.4 | .651 |
| Chris Ray | Flo | cl | 26 | 4 | 2 | .500 | 2 | .500 | 8 | 14 | 0 | .000 | 45 | 45 | 15 | 19.0 | .650 |
| Tim Redding | SF | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 102.3 | .590 |
| Mark Redman* | ChC | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 1 | 1 | 48.5 | .619 |
| Al Reyes | Flo | cl | 38 | 2 | 1 | .500 | 1 | .500 | 10 | 31 | 11 | .355 | 46 | 46 | 13 | 21.7 | .624 |
| Anthony Reyes | Hou | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 87.5 | .614 |
| Dennys Reyes* | Bal | mr | 31 | 1 | 0 | .000 | 0 | .000 | 2 | 23 | 8 | .348 | 30 | 30 | 9 | 24.1 | .511 |
| Jo-Jo Reyes* | Ari | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 93.7 | .565 |
| John Rheinecker* | StL | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 3 | .750 | 7 | 7 | 2 | 14.1 | .515 |
| Juan Rincon | Tex | mr | 29 | 8 | 5 | .625 | 3 | .375 | 5 | 54 | 27 | .500 | 57 | 57 | 24 | 25.8 | .593 |
| David Riske | Bal | mr | 31 | 33 | 26 | .788 | 7 | .212 | 0 | 38 | 7 | .184 | 66 | 66 | 56 | 19.5 | .619 |
| Mariano Rivera | Flo | cl | 38 | 47 | 40 | .851 | 7 | .149 | 1 | 31 | 12 | .387 | 67 | 67 | 58 | 17.1 | .669 |
| Saul Rivera | Cin | mr | 30 | 11 | 1 | .091 | 8 | .727 | 17 | 51 | 12 | .235 | 79 | 79 | 16 | 21.4 | .580 |
| Nate Robertson* | Was | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 92.2 | .623 |
| Fernando Rodney | KC | mr | 31 | 34 | 25 | .735 | 9 | .265 | 2 | 30 | 7 | .233 | 56 | 56 | 47 | 19.2 | .617 |
| Francisco Rodriguez | Col | cl | 26 | 36 | 30 | .833 | 6 | .167 | 0 | 20 | 7 | .350 | 60 | 60 | 52 | 20.6 | .609 |
| Wandy Rodriguez* | Min | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.4 | .610 |
| Kenny Rogers* | NYM | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 92.3 | .615 |
| J.C. Romero* | Was | mr | 32 | 2 | 1 | .500 | 1 | .500 | 15 | 21 | 5 | .238 | 42 | 42 | 9 | 19.7 | .543 |
| Ryan Rowland-Smith* | SF | mr | 25 | 5 | 3 | .600 | 2 | .400 | 7 | 17 | 9 | .529 | 25 | 25 | 10 | 19.3 | .608 |
| Jae Kuk Ryu | Sea | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 5 | 5 | 1 | 16.6 | .482 |
| Kirk Saarloos | Phi | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 21 | 12 | .571 | 26 | 22 | 7 | 36.4 | .570 |
| C.C. Sabathia* | ChW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 96.1 | .687 |
| Takashi Saito | SD | cl | 38 | 4 | 2 | .500 | 2 | .500 | 24 | 31 | 5 | .161 | 66 | 66 | 20 | 20.7 | .651 |
| Juan Salas | NYY | mr | 29 | 3 | 1 | .333 | 1 | .333 | 2 | 16 | 7 | .438 | 28 | 28 | 12 | 24.6 | .597 |
| Brad Salmon | Bal | mr | 28 | 4 | 1 | .250 | 2 | .500 | 2 | 27 | 12 | .444 | 23 | 23 | 8 | 23.7 | .616 |
| Chris Sampson | Min | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 25 | 3 | 2 | 76.6 | .630 |
| Anibal Sanchez | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 51.5 | .573 |
| Jonathan Sanchez* | KC | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 88.0 | .585 |
| Romulo Sanchez | Col | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 7 | 7 | 4 | 24.9 | .598 |
| Ervin Santana | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 90.8 | .619 |
| Johan Santana* | Mil | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 99.6 | .670 |
| Victor Santos | NYY | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 4 | .400 | 20 | 18 | 7 | 38.9 | .593 |
| Dennis Sarfate | Sea | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 2 | 2 | 1 | 22.0 | .705 |
| Joe Saunders* | SF | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 97.5 | .648 |
| Curt Schilling | Mil | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 97.4 | .677 |
| Jason Schmidt | Phi | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 124.7 | .588 |
| Scott Schoeneweis* | NYM | mr | 34 | 9 | 2 | .222 | 5 | .556 | 1 | 55 | 23 | .418 | 62 | 62 | 20 | 21.5 | .594 |
| Chris Schroder | Tor | mr | 29 | 3 | 2 | .667 | 1 | .333 | 3 | 48 | 17 | .354 | 56 | 56 | 39 | 21.6 | .618 |
| Rudy Seanez | Tor | mr | 39 | 5 | 0 | .000 | 3 | .600 | 9 | 35 | 14 | .400 | 44 | 44 | 15 | 22.3 | .594 |
| Bobby Seay* | NYY | mr | 30 | 3 | 1 | .333 | 2 | .667 | 10 | 19 | 4 | .211 | 28 | 28 | 7 | 15.8 | .657 |
| Chris Seddon* | Cin | sp | 24 | 3 | 1 | .333 | 0 | .000 | 0 | 4 | 0 | .000 | 9 | 9 | 5 | 28.7 | .554 |
| Zack Segovia | Tor | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 42.0 | .595 |
| Aaron Sele | NYY | mr | 38 | 1 | 0 | .000 | 0 | .000 | 2 | 32 | 18 | .563 | 31 | 31 | 15 | 27.6 | .607 |
| Jae Seo | LAD | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 77.3 | .599 |
| Tom Shearn | Flo | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 92.6 | .612 |
| Ben Sheets | Tex | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 104.5 | .631 |
| George Sherrill* | Min | mr | 31 | 19 | 11 | .579 | 8 | .421 | 17 | 63 | 24 | .381 | 69 | 69 | 28 | 19.5 | .609 |
| James Shields | LAD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 104.9 | .671 |
| Scot Shields | SF | mr | 32 | 5 | 3 | .600 | 2 | .400 | 14 | 29 | 4 | .138 | 58 | 58 | 20 | 23.3 | .606 |
| Brian Shouse* | Sea | mr | 39 | 4 | 3 | .750 | 1 | .250 | 18 | 30 | 7 | .233 | 52 | 52 | 13 | 12.7 | .642 |
| Carlos Silva | Det | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 93.7 | .666 |
| Jason Simontacchi | NYM | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 84.7 | .652 |
| Andrew Sisco* | LAD | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 13 | 13 | 2 | 23.8 | .560 |
| Doug Slaten* | ChW | mr | 28 | 2 | 1 | .500 | 1 | .500 | 8 | 34 | 9 | .265 | 39 | 39 | 6 | 16.6 | .598 |
| Kevin Slowey | NYY | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 99.4 | .681 |
| Joe Smith | ChW | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 17 | 10 | .588 | 19 | 19 | 5 | 22.6 | .623 |
| John Smoltz | ChW | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 104.0 | .655 |
| Ian Snell | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 104.3 | .645 |
| Kyle Snyder | Bos | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 1 | 38 | 16 | .421 | 46 | 46 | 14 | 29.5 | .574 |
| Andy Sonnanstine | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 86.1 | .659 |
| Joakim Soria | StL | cl | 24 | 38 | 33 | .868 | 5 | .132 | 0 | 20 | 3 | .150 | 55 | 55 | 48 | 18.9 | .652 |
| Rafael Soriano | Atl | mr | 28 | 6 | 1 | .167 | 2 | .333 | 19 | 47 | 13 | .277 | 88 | 88 | 25 | 18.7 | .679 |
| Jorge Sosa | Tor | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 91.6 | .605 |
| Jeremy Sowers* | Pit | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 90.3 | .638 |
| Justin Speier | Phi | mr | 34 | 26 | 22 | .846 | 4 | .154 | 0 | 47 | 12 | .255 | 51 | 51 | 46 | 18.7 | .671 |
| Ryan Speier | Min | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 16 | 4 | .250 | 15 | 15 | 5 | 30.4 | .607 |
| Russ Springer | Hou | mr | 39 | 48 | 38 | .792 | 10 | .208 | 0 | 39 | 16 | .410 | 79 | 79 | 68 | 21.3 | .629 |
| Chris Spurling | NYY | mr | 31 | 0 | 0 | .000 | 0 | .000 | 3 | 24 | 9 | .375 | 34 | 34 | 10 | 27.4 | .635 |
| Jason Stanford* | Was | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 1 | 50.3 | .629 |
| Mike Stanton* | Tor | mr | 41 | 2 | 0 | .000 | 1 | .500 | 2 | 32 | 10 | .313 | 37 | 37 | 4 | 30.6 | .640 |
| Tim Stauffer | KC | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 63.5 | .504 |
| Mitch Stetter* | Bos | mr | 27 | 1 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 0 | 8.5 | .529 |
| Huston Street | Det | cl | 24 | 39 | 32 | .821 | 7 | .179 | 3 | 36 | 6 | .167 | 53 | 53 | 44 | 20.3 | .670 |
| Jeff Suppan | Tex | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 103.6 | .616 |
| Jon Switzer* | Was | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 5 | 5 | 2 | 9.4 | .702 |
| Brian Tallet* | SF | mr | 30 | 12 | 9 | .750 | 2 | .167 | 8 | 25 | 7 | .280 | 52 | 52 | 26 | 21.4 | .628 |
| Taylor Tankersley* | Bal | mr | 25 | 3 | 0 | .000 | 2 | .667 | 9 | 34 | 10 | .294 | 48 | 48 | 12 | 21.6 | .581 |
| Jack Taschner* | Cin | mr | 30 | 5 | 2 | .400 | 3 | .600 | 4 | 43 | 20 | .465 | 57 | 57 | 17 | 22.5 | .559 |
| Jordan Tata | Cle | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 98.0 | .592 |
| Ty Taubenheim | Min | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 18.5 | .432 |
| Julian Tavarez | Phi | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 101.9 | .622 |
| Robinson Tejeda | Tex | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 101.9 | .581 |
| Joe Thatcher* | LAD | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 0 | 12 | 5 | .417 | 14 | 14 | 8 | 23.6 | .682 |
| Brad Thompson | LAD | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 87.0 | .607 |
| John Thomson | Col | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 99.0 | .636 |
| Matt Thornton* | Mil | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 7 | 40 | 19 | .475 | 69 | 69 | 22 | 20.4 | .637 |
| Erick Threets* | SF | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 31.0 | .500 |
| Mike Timlin | Mil | mr | 42 | 17 | 14 | .824 | 3 | .176 | 1 | 35 | 6 | .171 | 51 | 51 | 42 | 16.6 | .651 |
| Brett Tomko | Was | mr | 35 | 1 | 1 | 1.000 | 0 | .000 | 3 | 24 | 14 | .583 | 33 | 24 | 13 | 49.7 | .604 |
| Salomon Torres | Bos | mr | 36 | 4 | 1 | .250 | 1 | .250 | 5 | 42 | 15 | .357 | 49 | 49 | 15 | 21.8 | .597 |
| Josh Towers | Oak | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 1 | 1 | 98.2 | .653 |
| Billy Traber* | Tor | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 1 | .167 | 10 | 4 | 1 | 52.1 | .583 |
| Steve Trachsel | Phi | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 92.4 | .603 |
| Chin-hui Tsao | Pit | mr | 27 | 3 | 1 | .333 | 2 | .667 | 4 | 13 | 5 | .385 | 25 | 25 | 7 | 24.0 | .612 |
| Derrick Turnbow | ChC | mr | 30 | 58 | 50 | .862 | 7 | .121 | 1 | 23 | 5 | .217 | 72 | 72 | 67 | 19.9 | .559 |
| Jose Valverde | LAD | cl | 28 | 13 | 8 | .615 | 4 | .308 | 17 | 24 | 6 | .250 | 67 | 67 | 26 | 20.6 | .633 |
| John Van Benschoten | Pit | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 1 | 1 | 76.0 | .513 |
| Rick VandenHurk | ChW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 67.0 | .567 |
| Claudio Vargas | Oak | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 1 | 1 | 92.4 | .594 |
| Javier Vazquez | Cle | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 106.1 | .664 |
| Jose Veras | Det | mr | 27 | 2 | 0 | .000 | 1 | .500 | 2 | 12 | 3 | .250 | 13 | 13 | 4 | 24.2 | .541 |
| Justin Verlander | Tor | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 110.5 | .618 |
| Carlos Villanueva | LAD | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 39 | 9 | .231 | 50 | 50 | 16 | 27.9 | .578 |
| Oscar Villarreal | Oak | mr | 26 | 3 | 1 | .333 | 2 | .667 | 6 | 44 | 12 | .273 | 59 | 59 | 27 | 34.9 | .609 |
| Ron Villone* | StL | mr | 38 | 3 | 1 | .333 | 0 | .000 | 8 | 17 | 3 | .176 | 38 | 38 | 8 | 15.6 | .652 |
| Luis Vizcaino | Hou | mr | 33 | 5 | 2 | .400 | 3 | .600 | 8 | 50 | 20 | .400 | 56 | 56 | 17 | 28.5 | .602 |
| Edinson Volquez | Ari | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 92.8 | .599 |
| Billy Wagner* | ChW | cl | 36 | 16 | 9 | .563 | 3 | .188 | 13 | 32 | 10 | .313 | 60 | 60 | 29 | 20.0 | .630 |
| Adam Wainwright | ChC | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.5 | .626 |
| Tim Wakefield | Det | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 91.1 | .620 |
| Jamie Walker* | Atl | mr | 36 | 5 | 3 | .600 | 2 | .400 | 11 | 28 | 5 | .179 | 67 | 67 | 23 | 16.7 | .656 |
| Tyler Walker | Pit | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 5 | 5 | 3 | 24.8 | .605 |
| Chien-Ming Wang | SD | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 92.7 | .638 |
| Jarrod Washburn* | NYM | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.9 | .619 |
| Ehren Wassermann | Col | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 20 | 7 | .350 | 33 | 33 | 18 | 21.7 | .635 |
| David Weathers | Cle | cl | 38 | 45 | 41 | .911 | 4 | .089 | 2 | 46 | 11 | .239 | 64 | 64 | 56 | 16.7 | .596 |
| Jeff Weaver | Col | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 96.1 | .663 |
| Jered Weaver | Cin | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.8 | .643 |
| Brandon Webb | Sea | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 111.2 | .641 |
| Todd Wellemeyer | Det | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 83.9 | .589 |
| David Wells* | NYY | sp | 45 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.6 | .641 |
| Kip Wells | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 99.6 | .596 |
| Jake Westbrook | Was | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 95.0 | .629 |
| Dan Wheeler | Cle | mr | 30 | 5 | 4 | .800 | 1 | .200 | 2 | 20 | 9 | .450 | 38 | 38 | 19 | 25.5 | .652 |
| Bob Wickman | Tex | cl | 39 | 7 | 3 | .429 | 4 | .571 | 1 | 23 | 8 | .348 | 27 | 27 | 20 | 19.9 | .598 |
| Todd Williams | Mil | mr | 37 | 2 | 0 | .000 | 2 | 1.000 | 0 | 16 | 5 | .313 | 20 | 20 | 11 | 23.3 | .622 |
| Woody Williams | KC | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 95.4 | .626 |
| Scott Williamson | Tam | mr | 32 | 1 | 0 | .000 | 0 | .000 | 1 | 6 | 4 | .667 | 6 | 6 | 2 | 20.3 | .525 |
| Dontrelle Willis* | SF | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 101.3 | .593 |
| Brian Wilson | Was | cl | 26 | 2 | 0 | .000 | 1 | .500 | 9 | 11 | 4 | .364 | 19 | 19 | 3 | 12.7 | .702 |
| C.J. Wilson* | Pit | mr | 27 | 7 | 4 | .571 | 3 | .429 | 14 | 31 | 10 | .323 | 70 | 70 | 33 | 21.2 | .587 |
| Matt Wise | SF | mr | 32 | 0 | 0 | .000 | 0 | .000 | 2 | 17 | 9 | .529 | 33 | 33 | 15 | 28.9 | .617 |
| Randy Wolf* | Bos | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 91.1 | .629 |
| Brian Wolfe | StL | mr | 27 | 4 | 3 | .750 | 0 | .000 | 5 | 25 | 4 | .160 | 41 | 41 | 14 | 20.8 | .637 |
| Kerry Wood | Mil | mr | 31 | 4 | 4 | 1.000 | 0 | .000 | 1 | 11 | 2 | .182 | 16 | 16 | 11 | 23.8 | .596 |
| Jamey Wright | ChC | mr | 33 | 0 | 0 | .000 | 0 | .000 | 2 | 1 | 0 | .000 | 15 | 5 | 0 | 73.6 | .599 |
| Michael Wuertz | NYY | mr | 29 | 4 | 1 | .250 | 3 | .750 | 12 | 27 | 10 | .370 | 52 | 52 | 30 | 22.4 | .606 |
| Tyler Yates | NYM | mr | 30 | 5 | 2 | .400 | 3 | .600 | 7 | 40 | 18 | .450 | 75 | 75 | 17 | 22.7 | .607 |
| Shane Youman* | StL | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 1 | 14.5 | .621 |
| Chris Young | Sea | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 100.8 | .592 |
| Carlos Zambrano | Det | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 108.4 | .584 |
| Victor Zambrano | Atl | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 3 | 2 | 16.7 | .700 |
| Barry Zito* | Ari | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.8 | .610 |
| Joel Zumaya | SD | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 4 | 2 | 16.3 | .662 |