UsagePosition -- 2021 San Diego Padres
Regular season -- as of 9/26/2021
| Batter Status |
| S | Name | P | G | FLG |
| | Jo Adell | rf | 103 | 19 |
| f | Yordan Alvarez | dh | 5 | 0 |
| f | Anthony Bemboom | c | 57 | 52 |
| | Jon Berti | 2b | 105 | 96 |
| | Lewis Brinson | rf | 127 | 62 |
| f | Willie Calhoun | dh | 78 | 15 |
| | Jeimer Candelario | 1b | 145 | 145 |
| f | Jazz Chisholm | 2b | 57 | 40 |
| | Carlos Correa | ss | 157 | 155 |
| | Hunter Dozier | 1b | 119 | 131 |
| f | Estevan Florial | cf | 3 | 0 |
| f | Grayson Greiner | c | 50 | 27 |
| f | Oscar Hernandez | c | 11 | 0 |
| | Scott Kingery | 2b | 97 | 55 |
| | Jordan Luplow | lf | 78 | 42 |
| | Yoan Moncada | 3b | 140 | 140 |
| f | Logan Morrison | dh | 24 | 12 |
| | Cedric Mullins | cf | 130 | 130 |
| | John Ryan Murphy | c | 68 | 2 |
| | Joseph Odom | c | 49 | 83 |
| | Marcell Ozuna | dh | 162 | 162 |
| | Joc Pederson | lf | 116 | 113 |
| | Total | | 1881 | 1481 |
| Pitcher Status |
| S | Name | P | G | FLG | GS | FLGS |
| | Martin Perez | sp | 32 | 33 | 32 | 33 |
| | Lucas Giolito | sp | 32 | 33 | 32 | 33 |
| | Dylan Cease | sp | 32 | 15 | 32 | 15 |
| | Mike Fiers | sp | 30 | 32 | 30 | 32 |
| | Kevin Gausman | sp | 32 | 30 | 27 | 30 |
| | Sandy Alcantara | sp | 19 | 18 | 19 | 18 |
| f | Adrian Morejon | mr | 24 | 14 | 11 | 1 |
| | Josh James | mr | 35 | 13 | 5 | 0 |
| | Mychal Givens | mr | 59 | 21 | 0 | 0 |
| | Carson Fulmer | mr | 27 | 7 | 0 | 0 |
| | Josh Hader | cl | 57 | 60 | 0 | 0 |
| | Nick Anderson | cl | 51 | 57 | 0 | 0 |
| | James Karinchak | mr | 73 | 64 | 0 | 0 |
| | Luis Cessa | mr | 43 | 35 | 0 | 0 |
| f | Hansel Robles | mr | 49 | 57 | 0 | 0 |
| f | Michael Kopech | rp | 0 | 0 | 0 | 0 |
| | Franklyn Kilome | mr | 11 | 8 | 0 | 0 |
| | Total | | 188 | 162 | 188 | 162 |