UsagePosition -- 2021 St. Louis Cardinals
Regular season -- as of 9/26/2021
| Batter Status |
| S | Name | P | G | FLG |
| | Jesus Aguilar | 1b | 138 | 140 |
| | Tim Anderson | ss | 132 | 140 |
| | Nolan Arenado | 3b | 130 | 138 |
| | Alec Bohm | 3b | 119 | 131 |
| f | Starlin Castro | 2b | 43 | 47 |
| f | Austin Dean | lf | 8 | 4 |
| | Randal Grichuk | cf | 149 | 149 |
| | Jonah Heim | c | 35 | 13 |
| | Sam Hilliard | lf | 97 | 106 |
| f | Brock Holt | 3b | 97 | 42 |
| f | Erik Kratz | c | 43 | 24 |
| | Nick Markakis | rf | 100 | 65 |
| | Starling Marte | cf | 165 | 162 |
| | Sean Murphy | c | 116 | 123 |
| f | Sheldon Neuse | 2b | 0 | 0 |
| f | Tomas Nido | c | 19 | 9 |
| | Ryan O'Hearn | 1b | 113 | 39 |
| | Andrew Velazquez | ss | 108 | 125 |
| | Bradley Zimmer | cf | 54 | 41 |
| | Total | | 1666 | 1498 |
| Pitcher Status |
| S | Name | P | G | FLG | GS | FLGS |
| | Carlos Carrasco | sp | 32 | 32 | 32 | 32 |
| | Andrew Heaney | sp | 32 | 33 | 32 | 33 |
| | Robbie Ray | sp | 32 | 33 | 30 | 33 |
| | James Paxton | sp | 14 | 20 | 14 | 20 |
| f | Johan Oviedo | sp | 14 | 15 | 14 | 15 |
| | Matt Harvey | sp | 19 | 14 | 11 | 14 |
| f | Ljay Newsome | sp | 14 | 13 | 11 | 12 |
| | Ryan Brasier | mr | 68 | 48 | 3 | 0 |
| f | Bruce Zimmermann | sp | 5 | 6 | 3 | 3 |
| | Joakim Soria | mr | 59 | 49 | 0 | 0 |
| | Matt Strahm | mr | 51 | 42 | 0 | 0 |
| | Chris Stratton | mr | 73 | 45 | 0 | 0 |
| | Emilio Pagan | mr | 59 | 54 | 0 | 0 |
| | Joe Jimenez | mr | 70 | 44 | 0 | 0 |
| f | Tanner Rainey | mr | 54 | 13 | 0 | 0 |
| | Gregory Soto | mr | 75 | 60 | 0 | 0 |
| | Sam Selman | mr | 65 | 51 | 0 | 0 |
| f | Conner Menez | mr | 19 | 7 | 0 | 0 |
| f | Keone Kela | mr | 8 | 0 | 0 | 0 |
| f | Emmanuel Clase | mr | 0 | 0 | 0 | 0 |
| f | Garrett Crochet | mr | 14 | 1 | 0 | 0 |
| | Total | | 150 | 162 | 150 | 162 |