UsagePosition -- 2021 Pittsburgh Pirates
Regular season -- as of 9/26/2021
| Batter Status |
| S | Name | P | G | FLG |
| | Garrett Cooper | dh | 92 | 90 |
| | David Dahl | cf | 65 | 135 |
| | Tyler Flowers | c | 59 | 21 |
| | Freddy Galvis | ss | 127 | 135 |
| | Ben Gamel | rf | 108 | 120 |
| f | Jose Garcia | ss | 65 | 0 |
| | Dee Gordon | lf | 89 | 82 |
| | Luis Guillorme | 2b | 78 | 71 |
| f | Michael Hermosillo | lf | 19 | 0 |
| | Keston Hiura | 2b | 159 | 156 |
| f | Jace Peterson | rf | 70 | 73 |
| | Stephen Piscotty | rf | 122 | 118 |
| | Josh Reddick | rf | 151 | 128 |
| | Pedro Severino | c | 130 | 128 |
| | Mallex Smith | rf | 38 | 2 |
| | Donovan Solano | 2b | 146 | 143 |
| f | Tyrone Taylor | rf | 59 | 56 |
| f | Meibrys Viloria | c | 41 | 0 |
| | Total | | 1618 | 1458 |
| Pitcher Status |
| S | Name | P | G | FLG | GS | FLGS |
| | Zach Davies | sp | 32 | 33 | 32 | 33 |
| | Antonio Senzatela | sp | 32 | 32 | 32 | 32 |
| | Lance McCullers | sp | 30 | 32 | 30 | 32 |
| | Jordan Montgomery | sp | 27 | 24 | 27 | 24 |
| | Casey Mize | sp | 20 | 18 | 20 | 18 |
| f | Patrick Sandoval | sp | 24 | 10 | 16 | 10 |
| f | Jeff Samardzija | sp | 11 | 9 | 11 | 9 |
| f | Jordan Yamamoto | sp | 11 | 0 | 8 | 0 |
| f | Eric Lauer | sp | 11 | 0 | 5 | 0 |
| | Josh Osich | mr | 46 | 31 | 3 | 0 |
| f | Luis Garcia | mr | 14 | 9 | 3 | 4 |
| | Jake Woodford | mr | 34 | 15 | 3 | 0 |
| f | Jose Leclerc | cl | 5 | 5 | 0 | 0 |
| | Luke Jackson | mr | 51 | 48 | 0 | 0 |
| | Jose Alvarado | mr | 24 | 12 | 0 | 0 |
| | Ryan Helsley | mr | 34 | 24 | 0 | 0 |
| | Dillon Tate | mr | 32 | 28 | 0 | 0 |
| | Brooks Raley | mr | 57 | 41 | 0 | 0 |
| | David Phelps | mr | 59 | 40 | 0 | 0 |
| | John Schreiber | mr | 42 | 35 | 0 | 0 |
| | Connor Brogdon | mr | 24 | 24 | 0 | 0 |
| f | Humberto Castellanos | mr | 22 | 6 | 0 | 0 |
| | Total | | 190 | 162 | 190 | 162 |