UsagePosition -- 2021 Houston Astros
Regular season -- as of 9/26/2021
| Batter Status |
| S | Name | P | G | FLG |
| | Tucker Barnhart | c | 103 | 113 |
| f | Seth Brown | dh | 19 | 24 |
| | Kris Bryant | 3b | 92 | 99 |
| | Matt Davidson | dh | 54 | 46 |
| | Jaylin Davis | rf | 11 | 10 |
| f | Brandon Drury | 3b | 57 | 62 |
| | Mauricio Dubon | cf | 146 | 143 |
| f | Thairo Estrada | 2b | 70 | 100 |
| f | Luis Gonzalez | cf | 8 | 0 |
| | Bryce Harper | rf | 157 | 157 |
| | Daniel Murphy | 1b | 108 | 113 |
| | Jake Noll | 1b | 19 | 21 |
| | Jared Oliva | lf | 16 | 97 |
| | Danny Santana | 1b | 41 | 27 |
| | Max Stassi | c | 84 | 93 |
| | Trevor Story | ss | 159 | 159 |
| f | Andy Young | dh | 32 | 23 |
| | Total | | 1176 | 1287 |
| Pitcher Status |
| S | Name | P | G | FLG | GS | FLGS |
| f | Taijuan Walker | sp | 30 | 33 | 30 | 33 |
| | Justin Dunn | sp | 27 | 30 | 27 | 30 |
| f | Jon Gray | sp | 22 | 25 | 22 | 25 |
| f | Rich Hill | sp | 22 | 25 | 22 | 25 |
| | Daniel Ponce de Leon | sp | 25 | 22 | 22 | 22 |
| f | Drew Smyly | sp | 19 | 17 | 14 | 17 |
| | Mike Kickham | mr | 16 | 3 | 5 | 2 |
| | Cole Hamels | sp | 3 | 4 | 3 | 4 |
| | Justin Verlander | sp | 3 | 4 | 3 | 4 |
| | Brad Hand | cl | 62 | 53 | 0 | 0 |
| | Giovanny Gallegos | mr | 45 | 41 | 0 | 0 |
| | Junior Guerra | mr | 68 | 64 | 0 | 0 |
| | Dennis Santana | mr | 32 | 25 | 0 | 0 |
| f | Clay Holmes | mr | 3 | 1 | 0 | 0 |
| | Ian Gibaut | mr | 38 | 22 | 0 | 0 |
| | Craig Stammen | mr | 65 | 55 | 0 | 0 |
| f | Bryan Abreu | mr | 11 | 2 | 0 | 0 |
| | Tyler Matzek | mr | 57 | 51 | 0 | 0 |
| | Ben Heller | mr | 16 | 46 | 0 | 0 |
| | Matt Magill | mr | 30 | 19 | 0 | 0 |
| f | Ashton Goudeau | mr | 11 | 2 | 0 | 0 |
| f | Carlos Sanabria | mr | 5 | 0 | 0 | 0 |
| | Chad Sobotka | mr | 11 | 2 | 0 | 0 |
| | Glenn Sparkman | mr | 11 | 5 | 0 | 0 |
| | Total | | 148 | 162 | 148 | 162 |