League team vs team - 2016 American League
Regular season
| American League |
| Tor | Bal | TB | Bos | NYY | Cle | KC | Det | Min | ChW | LAA | Hou | Oak | Sea | Tex |
| Tor | x | 9-9 | 6-12 | 4-14 | 10-8 | 3-3 | 2-4 | 1-5 | 5-1 | 4-2 | 2-4 | 3-3 | 4-2 | 3-3 | 5-1 |
| Bal | 9-9 | x | 10-8 | 6-12 | 9-9 | 2-4 | 1-5 | 2-4 | 2-4 | 0-6 | 2-4 | 2-4 | 2-4 | 3-3 | 4-2 |
| TB | 12-6 | 8-10 | x | 9-9 | 9-9 | 4-2 | 2-4 | 0-6 | 5-1 | 3-3 | 3-3 | 1-5 | 2-4 | 2-4 | 3-3 |
| Bos | 14-4 | 12-6 | 9-9 | x | 14-4 | 3-3 | 5-1 | 3-3 | 5-1 | 2-4 | 4-2 | 4-2 | 3-3 | 5-1 | 4-2 |
| NYY | 8-10 | 9-9 | 9-9 | 4-14 | x | 1-5 | 3-3 | 2-4 | 3-3 | 5-1 | 4-2 | 5-1 | 2-4 | 5-1 | 4-2 |
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| Cle | 3-3 | 4-2 | 2-4 | 3-3 | 5-1 | x | 11-7 | 7-11 | 11-7 | 4-14 | 2-4 | 5-1 | 4-2 | 3-3 | 4-2 |
| KC | 4-2 | 5-1 | 4-2 | 1-5 | 3-3 | 7-11 | x | 6-12 | 12-6 | 12-6 | 5-1 | 1-5 | 4-2 | 4-2 | 4-2 |
| Det | 5-1 | 4-2 | 6-0 | 3-3 | 4-2 | 11-7 | 12-6 | x | 11-7 | 11-7 | 2-4 | 5-1 | 2-4 | 2-4 | 4-2 |
| Min | 1-5 | 4-2 | 1-5 | 1-5 | 3-3 | 7-11 | 6-12 | 7-11 | x | 4-14 | 2-4 | 3-3 | 2-4 | 4-2 | 4-2 |
| ChW | 2-4 | 6-0 | 3-3 | 4-2 | 1-5 | 14-4 | 6-12 | 7-11 | 14-4 | x | 5-1 | 5-1 | 3-3 | 4-2 | 5-1 |
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| LAA | 4-2 | 4-2 | 3-3 | 2-4 | 2-4 | 4-2 | 1-5 | 4-2 | 4-2 | 1-5 | x | 9-9 | 10-8 | 8-10 | 12-6 |
| Hou | 3-3 | 4-2 | 5-1 | 2-4 | 1-5 | 1-5 | 5-1 | 1-5 | 3-3 | 1-5 | 9-9 | x | 7-11 | 7-11 | 7-11 |
| Oak | 2-4 | 4-2 | 4-2 | 3-3 | 4-2 | 2-4 | 2-4 | 4-2 | 4-2 | 3-3 | 8-10 | 11-7 | x | 8-10 | 13-5 |
| Sea | 3-3 | 3-3 | 4-2 | 1-5 | 1-5 | 3-3 | 2-4 | 4-2 | 2-4 | 2-4 | 10-8 | 11-7 | 10-8 | x | 8-10 |
| Tex | 1-5 | 2-4 | 3-3 | 2-4 | 2-4 | 2-4 | 2-4 | 2-4 | 2-4 | 1-5 | 6-12 | 11-7 | 5-13 | 10-8 | x |
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